lactic acid has been researched along with Altitude Hypoxia in 26 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Altitude Hypoxia: Low ambient oxygen tension associated with ALTITUDE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study demonstrates that acute high altitude hypoxia upregulated the lactic acid/amino acid-pyruvate-TCA pathways and fatty acid oxidation, but downregulated glycolysis in the liver of mice." | 5.91 | Energy metabolic mechanisms for high altitude sickness: Downregulation of glycolysis and upregulation of the lactic acid/amino acid-pyruvate-TCA pathways and fatty acid oxidation. ( Jiang, C; Li, Y; Liao, N; Liu, G; Shang, X; Shao, D; Shi, J; Xu, F; Yin, D, 2023) |
| "1." | 2.68 | The effect of altitude hypoxia on glucose homeostasis in men. ( Dela, F; Galbo, H; Hansen, JM; Larsen, JJ; Olsen, NV, 1997) |
| "Under high-altitude hypoxia environment, the body is more prone to fatigue, which occurs in both peripheral muscles and the central nervous system (CNS)." | 1.91 | Monocarboxylate transporter-dependent mechanism is involved in the adaptability of the body to exercise-induced fatigue under high-altitude hypoxia environment. ( Gao, C; Li, Y; Pei, W; Yang, B, 2023) |
| "This study demonstrates that acute high altitude hypoxia upregulated the lactic acid/amino acid-pyruvate-TCA pathways and fatty acid oxidation, but downregulated glycolysis in the liver of mice." | 1.91 | Energy metabolic mechanisms for high altitude sickness: Downregulation of glycolysis and upregulation of the lactic acid/amino acid-pyruvate-TCA pathways and fatty acid oxidation. ( Jiang, C; Li, Y; Liao, N; Liu, G; Shang, X; Shao, D; Shi, J; Xu, F; Yin, D, 2023) |
| "Acute mountain sickness is caused by sub-acute hypoxia in healthy individuals going rapidly to altitude." | 1.39 | The antioxidative effect of a novel free radical scavenger 4'-hydroxyl-2-substituted phenylnitronyl nitroxide in acute high-altitude hypoxia mice. ( Fan, PC; Jia, ZP; Jing, LL; Li, L; Ma, HP, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.69) | 18.7374 |
| 1990's | 4 (15.38) | 18.2507 |
| 2000's | 6 (23.08) | 29.6817 |
| 2010's | 11 (42.31) | 24.3611 |
| 2020's | 3 (11.54) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, C | 1 |
| Yang, B | 1 |
| Li, Y | 2 |
| Pei, W | 1 |
| Liu, G | 1 |
| Liao, N | 1 |
| Shang, X | 1 |
| Xu, F | 1 |
| Yin, D | 1 |
| Shao, D | 1 |
| Jiang, C | 1 |
| Shi, J | 1 |
| Caris, AV | 1 |
| Thomatieli-Santos, RV | 1 |
| Matu, J | 1 |
| Deighton, K | 1 |
| Ispoglou, T | 1 |
| Shannon, OM | 1 |
| Duckworth, L | 1 |
| Fan, PC | 3 |
| Ma, HP | 3 |
| Jing, LL | 3 |
| Li, L | 2 |
| Jia, ZP | 3 |
| Laustsen, C | 1 |
| Lycke, S | 1 |
| Palm, F | 1 |
| Østergaard, JA | 1 |
| Bibby, BM | 1 |
| Nørregaard, R | 1 |
| Flyvbjerg, A | 1 |
| Pedersen, M | 1 |
| Ardenkjaer-Larsen, JH | 1 |
| Faulhaber, M | 5 |
| Wille, M | 2 |
| Gatterer, H | 3 |
| Heinrich, D | 1 |
| Burtscher, M | 5 |
| Avnstorp, MB | 1 |
| Rasmussen, P | 1 |
| Brassard, P | 1 |
| Seifert, T | 1 |
| Overgaard, M | 1 |
| Krustrup, P | 1 |
| Secher, NH | 1 |
| Nordsborg, NB | 1 |
| Jiang, W | 1 |
| Ren, J | 1 |
| Pocecco, E | 1 |
| Niedermeier, M | 1 |
| Huth, M | 1 |
| Dünnwald, T | 1 |
| Menz, V | 1 |
| Bernardi, L | 1 |
| Schommer, K | 1 |
| Wiesegart, N | 1 |
| Menold, E | 1 |
| Haas, U | 1 |
| Lahr, K | 1 |
| Buhl, H | 1 |
| Bärtsch, P | 1 |
| Dehnert, C | 1 |
| Yao, J | 1 |
| He, XR | 1 |
| Yang, Y | 1 |
| Chen, KM | 1 |
| Mairer, K | 1 |
| Philippe, M | 1 |
| Shen, G | 1 |
| Xie, K | 1 |
| Yan, Y | 1 |
| Jing, D | 1 |
| Tang, C | 1 |
| Wu, X | 1 |
| Liu, J | 1 |
| Sun, T | 1 |
| Zhang, J | 1 |
| Luo, E | 1 |
| Kornexl, E | 1 |
| Nachbauer, W | 1 |
| Szubski, C | 1 |
| Podolsky, A | 1 |
| Eldridge, MW | 1 |
| Richardson, RS | 1 |
| Knight, DR | 1 |
| Johnson, EC | 1 |
| Hopkins, SR | 1 |
| Johnson, DH | 1 |
| Michimata, H | 1 |
| Grassi, B | 1 |
| Feiner, J | 1 |
| Kurdak, SS | 1 |
| Bickler, PE | 1 |
| Severinghaus, JW | 1 |
| Wagner, PD | 1 |
| Basu, CK | 1 |
| Gautam, RK | 1 |
| Sharma, RP | 1 |
| Kumar, H | 1 |
| Tomar, OS | 1 |
| Sawhney, RC | 1 |
| Selvamurthy, W | 1 |
| Larsen, JJ | 1 |
| Hansen, JM | 1 |
| Olsen, NV | 2 |
| Galbo, H | 1 |
| Dela, F | 1 |
| Moore, TR | 1 |
| Casas, M | 1 |
| Casas, H | 1 |
| Pagés, T | 1 |
| Rama, R | 1 |
| Ricart, A | 1 |
| Ventura, JL | 1 |
| Ibáñez, J | 1 |
| Rodríguez, FA | 1 |
| Viscor, G | 1 |
| Robach, P | 1 |
| Déchaux, M | 1 |
| Jarrot, S | 1 |
| Vaysse, J | 1 |
| Schneider, JC | 1 |
| Mason, NP | 1 |
| Herry, JP | 1 |
| Gardette, B | 1 |
| Richalet, JP | 1 |
| Lundby, C | 2 |
| Møller, P | 1 |
| Kanstrup, IL | 1 |
| Araoz, M | 1 |
| van Hall, G | 1 |
| Yoshino, M | 1 |
| Murakami, K | 1 |
| Katsumata, Y | 1 |
| Takabayashi, A | 1 |
| Mori, S | 1 |
| Raynaud, J | 1 |
| Douguet, D | 1 |
| Legros, P | 1 |
| Capderou, A | 1 |
| Raffestin, B | 1 |
| Durand, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Cardiovascular and Metabolic Physiological Adaptations to Intermittent Hypoxia. Physiological Aspects and Expression of Receptors and Cellular Mediators[NCT02058823] | Phase 4 | 12 participants (Actual) | Interventional | 2013-08-07 | Terminated (stopped due to budget constraints) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 trials available for lactic acid and Altitude Hypoxia
| Article | Year |
|---|---|
Carbohydrate and Glutamine Supplementation Attenuates the Increase in Rating of Perceived Exertion during Intense Exercise in Hypoxia Similar to 4200 m.
Topics: Adult; Altitude; Altitude Sickness; Blood Gas Analysis; Dietary Carbohydrates; Dietary Supplements; | 2020 |
Seven Passive 1-h Hypoxia Exposures Do Not Prevent AMS in Susceptible Individuals.
Topics: Acclimatization; Adult; Altitude Sickness; Blood Gas Analysis; Double-Blind Method; Female; Heart Ra | 2016 |
Training in normobaric hypoxia and its effects on acute mountain sickness after rapid ascent to 4559 m.
Topics: Acclimatization; Adult; Altitude Sickness; Blood Gas Analysis; Double-Blind Method; Female; Heart Ra | 2010 |
The role of oxygen-increased respirator in humans ascending to high altitude.
Topics: Altitude; Altitude Sickness; Blood Gas Analysis; Heart Rate; Humans; Lactic Acid; Male; Malondialdeh | 2012 |
Exercise-induced VA/Q inequality in subjects with prior high-altitude pulmonary edema.
Topics: Adult; Aging; Altitude; Altitude Sickness; Blood Gas Analysis; Cardiac Output; Energy Metabolism; Ex | 1996 |
The effect of altitude hypoxia on glucose homeostasis in men.
Topics: Acclimatization; Adult; Altitude Sickness; Catecholamines; Exercise; Glucose; Glucose Clamp Techniqu | 1997 |
Intermittent hypobaric hypoxia induces altitude acclimation and improves the lactate threshold.
Topics: Acclimatization; Adult; Altitude Sickness; Anaerobic Threshold; Erythrocyte Count; Erythrocyte Indic | 2000 |
19 other studies available for lactic acid and Altitude Hypoxia
| Article | Year |
|---|---|
Monocarboxylate transporter-dependent mechanism is involved in the adaptability of the body to exercise-induced fatigue under high-altitude hypoxia environment.
Topics: Altitude; Altitude Sickness; Animals; Fatigue; Hypoxia; Lactic Acid; Rats | 2023 |
Energy metabolic mechanisms for high altitude sickness: Downregulation of glycolysis and upregulation of the lactic acid/amino acid-pyruvate-TCA pathways and fatty acid oxidation.
Topics: Altitude; Altitude Sickness; Amino Acids; Animals; Citric Acid Cycle; Down-Regulation; Fatty Acids; | 2023 |
A high fat breakfast attenuates the suppression of appetite and acylated ghrelin during exercise at simulated altitude.
Topics: Acetylation; Adult; Altitude; Altitude Sickness; Appetite Regulation; Blood Glucose; Breakfast; Diet | 2017 |
The antioxidative effect of a novel free radical scavenger 4'-hydroxyl-2-substituted phenylnitronyl nitroxide in acute high-altitude hypoxia mice.
Topics: Altitude; Altitude Sickness; Animals; Antioxidants; Catalase; Cyclic N-Oxides; Glutathione Peroxidas | 2013 |
High altitude may alter oxygen availability and renal metabolism in diabetics as measured by hyperpolarized [1-(13)C]pyruvate magnetic resonance imaging.
Topics: Alanine; Altitude; Altitude Sickness; Animals; Atmospheric Pressure; Bicarbonates; Blood Glucose; Di | 2014 |
Resting arterial oxygen saturation and breathing frequency as predictors for acute mountain sickness development: a prospective cohort study.
Topics: Acute Disease; Adult; Altitude Sickness; Atmosphere Exposure Chambers; Cohort Studies; Disease Susce | 2014 |
Cerebral water and ion balance remains stable when humans are exposed to acute hypoxic exercise.
Topics: Acid-Base Equilibrium; Adult; Altitude Sickness; Body Water; Brain; Brain Chemistry; Brain Edema; Ex | 2015 |
Anti-hypoxia Activity of the Novel NO Donor Acetyl Ferulic Isosorbide Mononitrate in Acute High-Altitude Hypoxia Mice.
Topics: Adenosine Triphosphate; Altitude Sickness; Animals; Blood Pressure; Catalase; Cerebrum; Glutathione | 2015 |
Anti-hypoxic activity at simulated high altitude was isolated in petroleum ether extract of Saussurea involucrata.
Topics: Adenosine Triphosphate; Alkanes; Altitude Sickness; Animals; Blood Glucose; Brain; Ca(2+) Mg(2+)-ATP | 2011 |
Changes in cardiac autonomic activity during a passive 8 hour acute exposure to 5 500 m normobaric hypoxia are not related to the development of acute mountain sickness.
Topics: Adult; Altitude Sickness; Autonomic Nervous System; Heart Rate; Humans; Hypoxia; Lactic Acid; Male; | 2012 |
[Cardiorespiratory and metabolic responses during mountain hiking and downhill skiing].
Topics: Adult; Aged; Altitude Sickness; Austria; Blood Pressure; Cardiovascular Diseases; Cross-Sectional St | 2005 |
Prediction of the susceptibility to AMS in simulated altitude.
Topics: Acclimatization; Acute Disease; Altitude; Altitude Sickness; Exercise; Humans; Hypercapnia; Hyperven | 2008 |
Metabolic responses during initial days of altitude acclimatization in the eastern Himalayas.
Topics: Acclimatization; Adult; Altitude; Altitude Sickness; Blood Pressure; Heart Rate; Humans; India; Lact | 1996 |
Pregnancy and hypoxia.
Topics: Aerospace Medicine; Altitude Sickness; Animals; Female; Fetus; Humans; Lactic Acid; Oxygen; Pregnanc | 1999 |
Operation Everest III: role of plasma volume expansion on VO(2)(max) during prolonged high-altitude exposure.
Topics: Adult; Altitude; Altitude Sickness; Atmosphere Exposure Chambers; Body Mass Index; Heart Rate; Human | 2000 |
Heart rate response to hypoxic exercise: role of dopamine D2-receptors and effect of oxygen supplementation.
Topics: Adult; Altitude Sickness; Blood Pressure; Epinephrine; Exercise; Female; Heart Rate; Hematocrit; Hum | 2001 |
Peak heart rate decreases with increasing severity of acute hypoxia.
Topics: Adaptation, Physiological; Adult; Altitude Sickness; Catecholamines; Exercise; Heart Rate; Humans; H | 2001 |
Stimulation of anaerobic metabolism in rats at high altitude hypoxia--adrenergic effects dependent on dietary states.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Altitude Sickness; Anaerobiosis; Animals; | 1987 |
Time course of muscular blood metabolites during forearm rhythmic exercise in hypoxia.
Topics: Adult; Altitude Sickness; Hemoglobins; Humans; Hydrogen-Ion Concentration; Hypoxia; Lactates; Lactic | 1986 |