lactic acid has been researched along with Alpers Diffuse Degeneration of Cerebral Gray Matter with Hepatic Cirrhosis in 4 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors describe a case of Alpers syndrome due to POLG1 mutations, including serial neuroimaging and pathological investigations, to illustrate two main points: (1) Unique characteristics evident on serial diffusion-weighted imaging can be a valuable indicator of Alpers syndrome; and (2) abnormal lipid metabolism can be present in Alpers syndrome, which may need to be considered when using a ketogenic diet." | 1.38 | Alpers syndrome: the natural history of a case highlighting neuroimaging, neuropathology, and fat metabolism. ( Khan, A; Kirton, A; Payne, E; Sarnat, HB; Trevenen, C; Wei, XC, 2012) |
| "Alpers syndrome is a progressive encephalopathy of early onset, characterized by rapid and severe developmental delay, intractable seizures and liver involvement in a previously healthy child." | 1.31 | Respiratory chain deficiency in Alpers syndrome. ( Chrétien, D; Cormier-Daire, V; de Lonlay, P; Gauthier-Villars, M; Jacquemin, E; Landrieu, P; Munnich, A; Rötig, A; Rustin, P, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khan, A | 1 |
| Trevenen, C | 1 |
| Wei, XC | 1 |
| Sarnat, HB | 1 |
| Payne, E | 1 |
| Kirton, A | 1 |
| Flemming, K | 1 |
| Ulmer, S | 1 |
| Duisberg, B | 1 |
| Hahn, A | 1 |
| Jansen, O | 1 |
| Morris, AA | 1 |
| Gauthier-Villars, M | 1 |
| Landrieu, P | 1 |
| Cormier-Daire, V | 1 |
| Jacquemin, E | 1 |
| Chrétien, D | 1 |
| Rötig, A | 1 |
| Rustin, P | 1 |
| Munnich, A | 1 |
| de Lonlay, P | 1 |
1 review available for lactic acid and Alpers Diffuse Degeneration of Cerebral Gray Matter with Hepatic Cirrhosis
| Article | Year |
|---|---|
Mitochondrial respiratory chain disorders and the liver.
Topics: Diffuse Cerebral Sclerosis of Schilder; DNA, Mitochondrial; Electron Transport; Humans; Hypoglycemia | 1999 |
3 other studies available for lactic acid and Alpers Diffuse Degeneration of Cerebral Gray Matter with Hepatic Cirrhosis
| Article | Year |
|---|---|
Alpers syndrome: the natural history of a case highlighting neuroimaging, neuropathology, and fat metabolism.
Topics: Biopsy; Diffuse Cerebral Sclerosis of Schilder; DNA Polymerase gamma; DNA-Directed DNA Polymerase; F | 2012 |
MR spectroscopic findings in a case of Alpers-Huttenlocher syndrome.
Topics: Aspartic Acid; Brain; Child; Creatine; Diffuse Cerebral Sclerosis of Schilder; Humans; Lactic Acid; | 2002 |
Respiratory chain deficiency in Alpers syndrome.
Topics: Atrophy; Biopsy, Needle; Cerebral Cortex; Child, Preschool; Consanguinity; Diagnosis, Differential; | 2001 |