lactic acid has been researched along with Aging in 264 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Poly-L-lactic acid (PLLA) is an injectable filler used for the treatment of facial fat loss secondary to HIV and aging." | 9.12 | Safety and efficacy of poly-L-lactic acid in HIV lipoatrophy and lipoatrophy of aging. ( Hanke, CW; Redbord, KP, 2007) |
| "To gain insight into the mechanism of sarcopenia and the protective effect of melatonin, the gastrocnemius muscles of young (3-4 months), early-aged (12 months), and old-aged (24 months) wild-type C57BL/6J female mice were examined by magnetic resonance and microscopy." | 7.88 | The Protective Effect of Melatonin Against Age-Associated, Sarcopenia-Dependent Tubular Aggregate Formation, Lactate Depletion, and Mitochondrial Changes. ( Acuña-Castroviejo, D; Diaz-Casado, ME; Escames, G; Fernández-Ortiz, M; López, LC; Mokhtar, DM; Rahim, I; Rusanova, I; Sayed, RKA, 2018) |
| "In this study, we report protective effects of dietary L-arginine (L-Arg) supplementation against oxidative stress and inflammation in aging rats during exhaustive exercise." | 7.74 | Potential ergogenic effects of L-arginine against oxidative and inflammatory stress induced by acute exercise in aging rats. ( Huang, CC; Lin, WT; Tsai, SC, 2008) |
| "The correlation between seizure-induced hypermetabolism and subsequent neuronal damage was studied in 10-day-old (P10), 21-day-old (P21), and adult rats subjected to lithium-pilocarpine status epilepticus (SE)." | 7.70 | Correlation between hypermetabolism and neuronal damage during status epilepticus induced by lithium and pilocarpine in immature and adult rats. ( Boyet, S; Dubé, C; Fernandes, MJ; Marescaux, C; Nehlig, A, 1999) |
| " Chronic administration of D-galactose has been reported to cause deterioration of cognitive and motor skills that are similar to symptoms of aging and, therefore, is regarded as a model of accelerated aging." | 5.36 | D-galactose effectiveness in modeling aging and therapeutic antioxidant treatment in mice. ( Irwin, MH; Parameshwaran, K; Pinkert, CA; Steliou, K, 2010) |
| "Poly-L-lactic acid (PLLA) is an injectable filler used for the treatment of facial fat loss secondary to HIV and aging." | 5.12 | Safety and efficacy of poly-L-lactic acid in HIV lipoatrophy and lipoatrophy of aging. ( Hanke, CW; Redbord, KP, 2007) |
| "To gain insight into the mechanism of sarcopenia and the protective effect of melatonin, the gastrocnemius muscles of young (3-4 months), early-aged (12 months), and old-aged (24 months) wild-type C57BL/6J female mice were examined by magnetic resonance and microscopy." | 3.88 | The Protective Effect of Melatonin Against Age-Associated, Sarcopenia-Dependent Tubular Aggregate Formation, Lactate Depletion, and Mitochondrial Changes. ( Acuña-Castroviejo, D; Diaz-Casado, ME; Escames, G; Fernández-Ortiz, M; López, LC; Mokhtar, DM; Rahim, I; Rusanova, I; Sayed, RKA, 2018) |
| " Lactic acid, EGCG, resveratrol, and retinol that can inhibit collagen synthesis effectively in a dose-dependent manner may be used for anti-fibrosis treatment purposes." | 3.74 | A rapid and sensitive screening system for human type I collagen with the aim of discovering potent anti-aging or anti-fibrotic compounds. ( Choo, HY; Hashem, MA; Jun, KY; Kwon, Y; Lee, E; Lim, S, 2008) |
| "In this study, we report protective effects of dietary L-arginine (L-Arg) supplementation against oxidative stress and inflammation in aging rats during exhaustive exercise." | 3.74 | Potential ergogenic effects of L-arginine against oxidative and inflammatory stress induced by acute exercise in aging rats. ( Huang, CC; Lin, WT; Tsai, SC, 2008) |
| " This is largely due to the historical experience of lactic acidosis with phenformin, despite the fact that metformin does not predispose to this when compared with other therapies." | 3.73 | Contraindications can damage your health--is metformin a case in point? ( Holstein, A; Stumvoll, M, 2005) |
| " Significant lactate signals were found in seven patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) during sleep periods, and none during periods of arousal." | 3.72 | Age-related changes in cerebral lactate metabolism in sleep-disordered breathing. ( Higami, S; Inoue, Y; Kamba, M; Suto, Y, 2003) |
| "Numerous studies using adult animal models suggest that dichloroacetate (DCA) may have neuroprotective properties by virtue of its ability to increase rates of metabolism and, therefore, clearance of brain lactic acidosis, which may accumulate during cerebral ischemia." | 3.70 | Age-related differences in the effect of dichloroacetate on postischemic lactate and acid clearance measured in vivo using magnetic resonance spectroscopy and microdialysis. ( Corbett, R; Garcia, D; Gee, J; Laptook, A; Silmon, S; Tollefsbol, G, 1998) |
| "The correlation between seizure-induced hypermetabolism and subsequent neuronal damage was studied in 10-day-old (P10), 21-day-old (P21), and adult rats subjected to lithium-pilocarpine status epilepticus (SE)." | 3.70 | Correlation between hypermetabolism and neuronal damage during status epilepticus induced by lithium and pilocarpine in immature and adult rats. ( Boyet, S; Dubé, C; Fernandes, MJ; Marescaux, C; Nehlig, A, 1999) |
| " No additional statistically significant improvements were observed during months 4-9, although effect sizes for the change in CE and GE at higher workloads indicated a dose-response pattern in men (CE at 75W: M1 g=0." | 2.84 | Effects of resistance training frequency on cardiorespiratory fitness in older men and women during intervention and follow-up. ( Fernández-Lezaun, E; Kyröläinen, H; Mäkinen, T; Schumann, M; Walker, S, 2017) |
| "Metformin was clinically well-tolerated." | 2.68 | Is metformin safe enough for ageing type 2 diabetic patients? ( Ambrosi, F; Filipponi, P; Gregorio, F; Manfrini, S; Testa, I, 1996) |
| "Prenatal overnutrition predisposed for hyperglycaemia and hyperlactataemia, whereas undernutrition predisposed for hypercholesterolaemia upon exposure to an obesogenic diet." | 1.42 | Late gestation under- and overnutrition have differential impacts when combined with a post-natal obesogenic diet on glucose-lactate-insulin adaptations during metabolic challenges in adolescent sheep. ( Axel, AM; Birtwistle, M; Husted, SV; Johnsen, L; Kadarmideen, HN; Khanal, P; Kongsted, AH; Markussen, B; Nielsen, MO; Pandey, D; Pedersen, KL, 2015) |
| " A questionnaire was used to evaluate patient satisfaction and the incidence of adverse reactions." | 1.40 | The safety and efficacy of poly-L-lactic acid on sunken cheeks in Asians. ( Kim, HS; Kim, SM; Lee, JD; Lee, SJ; Suh, DH, 2014) |
| " Chronic administration of D-galactose has been reported to cause deterioration of cognitive and motor skills that are similar to symptoms of aging and, therefore, is regarded as a model of accelerated aging." | 1.36 | D-galactose effectiveness in modeling aging and therapeutic antioxidant treatment in mice. ( Irwin, MH; Parameshwaran, K; Pinkert, CA; Steliou, K, 2010) |
| "The canine counterpart of senile dementia of the Alzheimer type (ccSDAT) is considered a promising model for examining behavioral, cellular and molecular processes involved in early phases of human brain aging and Alzheimer disease (AD)." | 1.33 | Severe cognitive impairment correlates with higher cerebrospinal fluid levels of lactate and pyruvate in a canine model of senile dementia. ( Andrade, C; Carrasco, JL; Mahy, N; Mas, E; Mascort, J; Pugliese, M, 2005) |
| "With hypoxemia, time had a significant effect on V(O2) and body temperature in an age-dependent fashion: that is, whereas the 1 week group and the 4-5 week group showed both variables decreasing over time, the 2-3 week group showed no drop in V(O2) and a small increase in body temperature over time." | 1.31 | Age-dependent metabolic effects of repeated hypoxemia in piglets. ( Barter, J; Côté, A; Meehan, B, 2000) |
| "Many enzyme activities in Alzheimer's disease (AD) are changed." | 1.30 | Affected enzyme activities in Alzheimer's disease are sensitive to antemortem hypoxia. ( Bothmer, J; Jolles, J; Meng, F; Terwel, D; Wolf, E, 1998) |
| "Urea levels were highest in controls, and lowest in cafeteria rats fed from day 30, a consequence of the different setting of nitrogen sparing induced by the timing of initiation of cafeteria feeding." | 1.29 | Long-term effects of cafeteria diet feeding on young Wistar rats. ( Alemany, M; Arola, L; Salvadó, J; Segués, T, 1994) |
| " The dose was derived after assessment of LD50 i." | 1.28 | [Acute changes in the body of laboratory rats during development after the parenteral administration of the herbicide Zeazin S-40. I. Determination of LD50 and other biochemical findings]. ( Mourek, J; Trojanová, M, 1990) |
| " At the same time there was a progressive shift of the insulin dose-response curve to the right, indicating diminished insulin sensitivity and a marked decrease in maximum insulin responsiveness." | 1.27 | Glucose uptake and insulin sensitivity in rat muscle: changes during 3-96 weeks of age. ( Belur, E; Dluz, SM; Goodman, MN; McElaney, MA; Ruderman, NB, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 40 (15.15) | 18.7374 |
| 1990's | 67 (25.38) | 18.2507 |
| 2000's | 84 (31.82) | 29.6817 |
| 2010's | 65 (24.62) | 24.3611 |
| 2020's | 8 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Bastian, C | 2 |
| Zerimech, S | 1 |
| Nguyen, H | 1 |
| Doherty, C | 2 |
| Franke, C | 2 |
| Faris, A | 2 |
| Quinn, J | 2 |
| Baltan, S | 2 |
| Wei, L | 1 |
| Yang, X | 1 |
| Wang, J | 1 |
| Wang, Z | 1 |
| Wang, Q | 1 |
| Ding, Y | 1 |
| Yu, A | 1 |
| Lepers, R | 1 |
| Bontemps, B | 1 |
| Louis, J | 1 |
| Brunet, S | 1 |
| Gizak, A | 1 |
| McCubrey, JA | 1 |
| Rakus, D | 1 |
| Diry, A | 1 |
| Ratel, S | 5 |
| Bardin, J | 1 |
| Armstrong, N | 2 |
| De Larochelambert, Q | 1 |
| Thomas, C | 1 |
| Maciejewski, H | 1 |
| Nagata, S | 1 |
| Tatematsu, K | 1 |
| Kansaku, K | 1 |
| Inoue, Y | 2 |
| Kobayashi, M | 1 |
| Shirasuna, K | 1 |
| Iwata, H | 1 |
| Cai, XT | 1 |
| Li, H | 1 |
| Borch Jensen, M | 1 |
| Maksoud, E | 1 |
| Borneo, J | 1 |
| Liang, Y | 1 |
| Quake, SR | 1 |
| Luo, L | 1 |
| Haghighi, P | 1 |
| Jasper, H | 1 |
| Fernández-Lezaun, E | 1 |
| Schumann, M | 1 |
| Mäkinen, T | 1 |
| Kyröläinen, H | 1 |
| Walker, S | 1 |
| Nakano, F | 1 |
| Sakushima, K | 1 |
| Umeki, R | 1 |
| Yabe, I | 1 |
| Endoh, A | 1 |
| Sasaki, H | 1 |
| Son, MJ | 1 |
| Ryu, JS | 1 |
| Kim, JY | 1 |
| Kwon, Y | 2 |
| Chung, KS | 1 |
| Mun, SJ | 1 |
| Cho, YS | 1 |
| Paunksnis, MR | 1 |
| Evangelista, AL | 1 |
| La Scala Teixeira, CV | 1 |
| Alegretti João, G | 1 |
| Pitta, RM | 1 |
| Alonso, AC | 1 |
| Figueira, A | 1 |
| Serra, AJ | 1 |
| Baker, JS | 1 |
| Schoenfeld, BJ | 1 |
| Bocalini, DS | 1 |
| Redlberger, S | 1 |
| Fischer, S | 1 |
| Köhler, H | 1 |
| Diller, R | 1 |
| Reinhold, P | 1 |
| Sayed, RKA | 1 |
| Fernández-Ortiz, M | 1 |
| Diaz-Casado, ME | 1 |
| Rusanova, I | 1 |
| Rahim, I | 1 |
| Escames, G | 1 |
| López, LC | 1 |
| Mokhtar, DM | 1 |
| Acuña-Castroviejo, D | 1 |
| Datta, S | 1 |
| Chakrabarti, N | 1 |
| Fimognari, N | 1 |
| Hollings, A | 1 |
| Lam, V | 1 |
| Tidy, RJ | 1 |
| Kewish, CM | 1 |
| Albrecht, MA | 1 |
| Takechi, R | 1 |
| Mamo, JCL | 1 |
| Hackett, MJ | 1 |
| Rinnerthaler, M | 1 |
| Richter, K | 1 |
| Vestergaard, MB | 1 |
| Jensen, ML | 1 |
| Arngrim, N | 1 |
| Lindberg, U | 1 |
| Larsson, HB | 1 |
| Arakelian, VM | 1 |
| Goulart, CDL | 1 |
| Mendes, RG | 2 |
| Sousa, NM | 1 |
| Trimer, R | 1 |
| Guizilini, S | 1 |
| Sampaio, LMM | 1 |
| Baldissera, V | 1 |
| Arena, R | 2 |
| Reis, MS | 1 |
| Borghi-Silva, A | 2 |
| Yanase, S | 1 |
| Ishii, T | 2 |
| Yasuda, K | 1 |
| Ishii, N | 2 |
| Akaishi, T | 1 |
| Onishi, E | 1 |
| Abe, M | 1 |
| Toyama, H | 1 |
| Ishizawa, K | 1 |
| Kumagai, M | 1 |
| Kubo, R | 1 |
| Nakashima, I | 1 |
| Aoki, M | 1 |
| Yamauchi, M | 1 |
| Zhang, X | 3 |
| Wu, J | 1 |
| Liu, H | 1 |
| Greaney, JL | 1 |
| Schwartz, CE | 1 |
| Edwards, DG | 1 |
| Fadel, PJ | 1 |
| Farquhar, WB | 1 |
| Simões, RP | 1 |
| Castello-Simões, V | 1 |
| Archiza, B | 1 |
| Dos Santos, DA | 1 |
| Bonjorno, JC | 1 |
| de Oliveira, CR | 1 |
| Catai, AM | 1 |
| Kavanagh, OV | 1 |
| Adair, BM | 1 |
| Welsh, M | 1 |
| Earley, B | 1 |
| Ding, F | 1 |
| Yao, J | 1 |
| Rettberg, JR | 1 |
| Chen, S | 1 |
| Brinton, RD | 1 |
| Luebberding, S | 1 |
| Alexiades-Armenakas, M | 1 |
| Watanabe, Y | 1 |
| Madarame, H | 1 |
| Ogasawara, R | 1 |
| Nakazato, K | 1 |
| Yu, TC | 1 |
| Yang, FL | 1 |
| Hsu, BG | 1 |
| Wu, WT | 1 |
| Chen, SC | 1 |
| Lee, RP | 1 |
| Subeq, YM | 1 |
| Ono, K | 1 |
| Kitagawa, M | 1 |
| Ito, D | 1 |
| Tanaka, N | 1 |
| Watari, T | 1 |
| Leontieva, OV | 1 |
| Blagosklonny, MV | 1 |
| Nybo, L | 1 |
| Schmidt, JF | 1 |
| Fritzdorf, S | 1 |
| Nordsborg, NB | 1 |
| Suh, DH | 1 |
| Lee, SJ | 1 |
| Kim, SM | 1 |
| Lee, JD | 1 |
| Kim, HS | 1 |
| Smith, C | 1 |
| Viljoen, JT | 1 |
| McGeachie, L | 1 |
| Khanal, P | 1 |
| Axel, AM | 1 |
| Kongsted, AH | 1 |
| Husted, SV | 1 |
| Johnsen, L | 1 |
| Pandey, D | 1 |
| Pedersen, KL | 1 |
| Birtwistle, M | 1 |
| Markussen, B | 1 |
| Kadarmideen, HN | 1 |
| Nielsen, MO | 1 |
| Galeffi, F | 1 |
| Shetty, PK | 1 |
| Sadgrove, MP | 1 |
| Turner, DA | 1 |
| Santos-Lozano, A | 1 |
| Angulo, AM | 1 |
| Collado, PS | 1 |
| Sanchis-Gomar, F | 1 |
| Pareja-Galeano, H | 1 |
| Fiuza-Luces, C | 1 |
| Lucia, A | 1 |
| Garatachea, N | 1 |
| Massimino, ML | 1 |
| Peggion, C | 1 |
| Loro, F | 1 |
| Stella, R | 1 |
| Megighian, A | 1 |
| Scorzeto, M | 1 |
| Blaauw, B | 1 |
| Toniolo, L | 1 |
| Sorgato, MC | 1 |
| Reggiani, C | 1 |
| Bertoli, A | 1 |
| Zelenka, J | 1 |
| Dvořák, A | 1 |
| Alán, L | 1 |
| Vulevic, J | 1 |
| Juric, A | 1 |
| Walton, GE | 1 |
| Claus, SP | 1 |
| Tzortzis, G | 1 |
| Toward, RE | 1 |
| Gibson, GR | 1 |
| Réus, GZ | 1 |
| Scaini, G | 1 |
| Titus, SE | 1 |
| Furlanetto, CB | 1 |
| Wessler, LB | 1 |
| Ferreira, GK | 1 |
| Gonçalves, CL | 1 |
| Jeremias, GC | 1 |
| Quevedo, J | 1 |
| Streck, EL | 1 |
| Chen, Y | 1 |
| Kim, H | 1 |
| Bok, R | 1 |
| Sukumar, S | 1 |
| Mu, X | 1 |
| Sheldon, RA | 1 |
| Barkovich, AJ | 1 |
| Ferriero, DM | 1 |
| Xu, D | 1 |
| Harris, RA | 2 |
| Tindale, L | 1 |
| Lone, A | 1 |
| Singh, O | 1 |
| Macauley, SL | 1 |
| Stanley, M | 1 |
| Holtzman, DM | 1 |
| Bartha, R | 1 |
| Cumming, RC | 1 |
| Mdaki, KS | 1 |
| Larsen, TD | 1 |
| Weaver, LJ | 1 |
| Baack, ML | 1 |
| Consitt, LA | 1 |
| Saxena, G | 1 |
| Saneda, A | 1 |
| Houmard, JA | 1 |
| Pinto, RR | 1 |
| Karabulut, M | 1 |
| Poton, R | 1 |
| Polito, MD | 1 |
| Niel, R | 1 |
| Ayachi, M | 1 |
| Mille-Hamard, L | 1 |
| Le Moyec, L | 1 |
| Savarin, P | 1 |
| Clement, MJ | 1 |
| Besse, S | 2 |
| Launay, T | 1 |
| Billat, VL | 1 |
| Momken, I | 1 |
| Sobolev, AP | 1 |
| Mannina, L | 1 |
| Costanzo, M | 1 |
| Cisterna, B | 1 |
| Malatesta, M | 1 |
| Zancanaro, C | 1 |
| Hashem, MA | 1 |
| Jun, KY | 1 |
| Lee, E | 1 |
| Lim, S | 1 |
| Choo, HY | 1 |
| Hagopian, K | 2 |
| Ramsey, JJ | 2 |
| Weindruch, R | 2 |
| Levy, RM | 1 |
| Redbord, KP | 2 |
| Hanke, CW | 2 |
| Wray, DW | 1 |
| Nishiyama, SK | 1 |
| Richardson, RS | 2 |
| Masuda, S | 1 |
| Hayashi, T | 1 |
| Egawa, T | 1 |
| Taguchi, S | 1 |
| Zhou, Q | 1 |
| Lam, PY | 1 |
| Han, D | 1 |
| Cadenas, E | 1 |
| Gybina, AA | 1 |
| Tkac, I | 1 |
| Prohaska, JR | 1 |
| Torres, S | 1 |
| Salgado-Ceballos, H | 1 |
| Torres, JL | 1 |
| Orozco-Suarez, S | 1 |
| Díaz-Ruíz, A | 1 |
| Martínez, A | 1 |
| Rivera-Cruz, M | 1 |
| Ríos, C | 1 |
| Lara, A | 1 |
| Collado, C | 1 |
| Guizar-Sahagún, G | 1 |
| Cunha, RR | 1 |
| Cunha, VN | 1 |
| Segundo, PR | 1 |
| Moreira, SR | 1 |
| Kokubun, E | 1 |
| Campbell, CS | 1 |
| de Oliveira, RJ | 1 |
| Simões, HG | 1 |
| Hyder, A | 1 |
| Laue, C | 1 |
| Schrezenmeir, J | 1 |
| Wigren, HK | 1 |
| Rytkönen, KM | 1 |
| Porkka-Heiskanen, T | 2 |
| Mujika, I | 2 |
| Spencer, M | 1 |
| Santisteban, J | 1 |
| Goiriena, JJ | 1 |
| Bishop, D | 1 |
| Schmidt, B | 1 |
| de Assis, AM | 1 |
| Battu, CE | 1 |
| Rieger, DK | 1 |
| Hansen, F | 1 |
| Sordi, F | 1 |
| Longoni, A | 1 |
| Hoefel, AL | 1 |
| Farina, M | 1 |
| Gonçalves, CA | 1 |
| Souza, DO | 1 |
| Perry, ML | 1 |
| Hulmi, JJ | 1 |
| Myllymäki, T | 1 |
| Tenhumäki, M | 1 |
| Mutanen, N | 1 |
| Puurtinen, R | 1 |
| Paulsen, G | 1 |
| Mero, AA | 1 |
| Buchheit, M | 1 |
| Duché, P | 3 |
| Laursen, PB | 1 |
| Holviala, J | 1 |
| Häkkinen, A | 1 |
| Karavirta, L | 1 |
| Nyman, K | 1 |
| Izquierdo, M | 2 |
| Gorostiaga, EM | 2 |
| Avela, J | 1 |
| Korhonen, J | 1 |
| Knuutila, VP | 1 |
| Kraemer, WJ | 2 |
| Häkkinen, K | 3 |
| Contarteze, RV | 1 |
| de Alencar Mota, CS | 1 |
| de Oliveira, CA | 1 |
| de Almeida Leme, JA | 1 |
| Bottcher, LB | 1 |
| de Mello, MA | 1 |
| Luciano, E | 1 |
| Fang, Y | 1 |
| Mo, X | 1 |
| Guo, W | 1 |
| Zhang, M | 1 |
| Zhang, P | 1 |
| Wang, Y | 1 |
| Rong, X | 1 |
| Tian, J | 1 |
| Sun, X | 1 |
| Ross, JM | 1 |
| Öberg, J | 1 |
| Brené, S | 1 |
| Coppotelli, G | 1 |
| Terzioglu, M | 1 |
| Pernold, K | 1 |
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| Sitnikov, R | 1 |
| Kehr, J | 1 |
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| Hoffer, BJ | 1 |
| Olson, L | 1 |
| McKeever, KH | 1 |
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| Leen, WG | 1 |
| Willemsen, MA | 1 |
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| Essén-Gustavsson, B | 2 |
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| Fisher, JP | 1 |
| Hartwich, D | 1 |
| Seifert, T | 1 |
| Olesen, ND | 1 |
| McNulty, CL | 1 |
| Nielsen, HB | 1 |
| van Lieshout, JJ | 1 |
| Secher, NH | 1 |
| Sadick, NS | 2 |
| Manhas-Bhutani, S | 1 |
| Krueger, N | 1 |
| Andrieux, C | 1 |
| Membré, JM | 1 |
| Cayuela, C | 1 |
| Antoine, JM | 1 |
| Bedu, M | 2 |
| Hennegrave, A | 2 |
| Doré, E | 1 |
| Timmons, BW | 2 |
| Bar-Or, O | 2 |
| Riddell, MC | 2 |
| Schteingart, HF | 1 |
| Cigorraga, SB | 1 |
| Calandra, RS | 1 |
| Gonzalez-Calvar, SI | 1 |
| Kates, AM | 2 |
| Herrero, P | 2 |
| Dence, C | 1 |
| Soto, P | 1 |
| Srinivasan, M | 1 |
| Delano, DG | 1 |
| Ehsani, A | 1 |
| Gropler, RJ | 2 |
| Capodaglio, EM | 1 |
| Saibene, F | 1 |
| Markel, TA | 1 |
| Daley, JC | 1 |
| Hogeman, CS | 1 |
| Herr, MD | 1 |
| Khan, MH | 1 |
| Gray, KS | 1 |
| Kunselman, AR | 2 |
| Sinoway, LI | 2 |
| Yamaguchi, M | 1 |
| Uchiyama, S | 1 |
| Tsukamoto, Y | 1 |
| Danis, A | 1 |
| Kyriazis, Y | 1 |
| Klissouras, V | 1 |
| Finsterer, J | 1 |
| Sumida, KD | 3 |
| Arimoto, SM | 1 |
| Catanzaro, MJ | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effects of HOST-DM059 Prebiotic Supplementation on Gut Bacterial Metabolites, and Markers of Systemic Inflammation in Adults With and Without Hyperpnoea-Induced Bronchoconstriction: A Double-Blind, Placebo-Controlled, Crossover Trial.[NCT02872675] | 17 participants (Actual) | Interventional | 2017-11-15 | Completed | |||
| Impact of Breakfast Consumption Timing on Postprandial Glycaemia and Insulinaemia in Adolescent Girls Who Habitually Skip Breakfast[NCT05000944] | 15 participants (Actual) | Interventional | 2021-11-18 | Completed | |||
| Effect of Gastric Bypass-induced Weight Loss on Myocardial Structure, Function and Metabolism[NCT00841009] | 18 participants (Actual) | Observational | 2005-07-31 | Completed | |||
| Sex and Obesity Effects on Myocardial Blood Flow and Metabolism[NCT00776035] | 10 participants (Anticipated) | Observational | 2008-01-31 | Active, not recruiting | |||
| The Effects of Lifelong Endurance and Strength Training on the Central and Peripheral Cardiovascular Responses[NCT04013022] | 48 participants (Anticipated) | Observational | 2019-08-01 | Recruiting | |||
| Exercise Conditioning in Elderly Patients With Heart Failure[NCT01113840] | 201 participants (Actual) | Interventional | 1993-07-31 | Completed | |||
| Insulin and Sarcopenia in the Elderly[NCT00690534] | Phase 1 | 88 participants (Actual) | Interventional | 2005-09-30 | Completed | ||
| Muscle Regrowth During Physical Rehabilitation and Amino Acid Supplementation[NCT00760383] | 60 participants (Actual) | Interventional | 2008-06-30 | Completed | |||
| Nutritional and Contractile Regulation of Muscle Growth (Cycle 2)[NCT00891696] | Phase 1 | 144 participants (Actual) | Interventional | 2009-04-30 | Completed | ||
| Effects of Smartphone Usage Duration on Neck Dysfunction in Young Versus Middle Aged Patients With Chronic Mechanical Neck Pain[NCT03745469] | 80 participants (Actual) | Observational | 2018-11-20 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Analysis was performed using the Analyze 11 software package with semi-automated delineation of quadriceps, hamstrings, and adductors boarders. Using thresholding methods, the software can differentiate operator-delineated parameters set to distinguish muscle from non-muscle (i.e., adipose tissue) using voxel intensity within each border region for quantitative determination of muscle volume. (NCT00760383)
Timeframe: 6 weeks
| Intervention | Volume (cm^3) (Mean) |
|---|---|
| EAA+PT | 109 |
| ALA+PT | 108 |
(NCT00760383)
Timeframe: 6 weeks
| Intervention | Newtons (Mean) |
|---|---|
| EAA+PT | 65 |
| ALA+PT | 81 |
(NCT00760383)
Timeframe: 6 weeks
| Intervention | seconds (Mean) |
|---|---|
| EAA+PT | 7 |
| ALA+PT | 8 |
13 reviews available for lactic acid and Aging
| Article | Year |
|---|---|
Role of Brain Glycogen During Ischemia, Aging and Cell-to-Cell Interactions.
Topics: Aging; Axons; Brain; Brain Ischemia; Cell Communication; Glucose; Glycogen; Lactic Acid; Oligodendro | 2019 |
The Influence of Calcium on the Skin pH and Epidermal Barrier During Aging.
Topics: Aging; Calcium; Epidermis; Fatty Acids, Nonesterified; Humans; Hydrogen-Ion Concentration; Keratinoc | 2018 |
Metabolic Biomarkers in Nematode C. elegans During Aging.
Topics: Aging; Animals; Caenorhabditis elegans; Energy Metabolism; Lactic Acid; Mitochondria; Oxidative Phos | 2019 |
Facial volume augmentation in 2014: overview of different filler options.
Topics: Aging; Cosmetic Techniques; Durapatite; Face; Humans; Hyaluronic Acid; Injections; Lactic Acid; Off- | 2013 |
Volumizing the face with soft tissue fillers.
Topics: Adjuvants, Immunologic; Aging; Biocompatible Materials; Collagen; Cosmetic Techniques; Dimethylpolys | 2011 |
Fillers: from the past to the future.
Topics: Adipose Tissue; Aging; Animals; Biocompatible Materials; Cellulose; Collagen; Durapatite; Forecastin | 2012 |
A novel approach to structural facial volume replacement.
Topics: Aging; Biocompatible Materials; Collagen; Cosmetic Techniques; Esthetics; Face; Female; Humans; Hyal | 2013 |
Poly-L-lactic acid: a perspective from my practice.
Topics: Absorbable Implants; Aging; Biocompatible Materials; Cosmetic Techniques; Face; Hand; HIV-Associated | 2008 |
Dermatological implications of skeletal aging: a focus on supraperiosteal volumization for perioral rejuvenation.
Topics: Adipose Tissue; Adult; Aged; Aging; Cephalometry; Cosmetic Techniques; Face; Facial Bones; Facial Mu | 2008 |
Tissue redox-state potential (E'0)--as regulator of physiological processes.
Topics: Aging; Animals; Biological Transport, Active; Blood Physiological Phenomena; Cell Membrane; Cell Phy | 1983 |
[Cytokines, immunostimulation and lactic enzymes].
Topics: Age Factors; Aging; Animals; Bacillus subtilis; Child; Child, Preschool; Cytokines; Enzymes; Humans; | 1994 |
Effect of glucose on perinatal hypoxic-ischemic brain damage.
Topics: Aging; Animals; Animals, Newborn; Brain; Brain Damage, Chronic; Brain Ischemia; Glucose; Humans; Hyp | 1992 |
Exercise capacity in the elderly.
Topics: Adult; Aged; Aging; Anaerobiosis; Blood Pressure; Cardiac Output; Female; Humans; Lactates; Lactic A | 1986 |
23 trials available for lactic acid and Aging
| Article | Year |
|---|---|
Effects of resistance training frequency on cardiorespiratory fitness in older men and women during intervention and follow-up.
Topics: Absorptiometry, Photon; Age Factors; Aged; Aging; Biomarkers; Body Composition; Cardiorespiratory Fi | 2017 |
Higher physiological vulnerability to hypoxic exposure with advancing age in the human brain.
Topics: Adolescent; Adult; Aging; Cerebrovascular Circulation; Female; Humans; Hypoxia, Brain; Lactic Acid; | 2020 |
Effect of very low-intensity resistance training with slow movement on muscle size and strength in healthy older adults.
Topics: Action Potentials; Age Factors; Aged; Aging; Biomarkers; Blood Pressure; Electromyography; Female; H | 2014 |
Influence of galacto-oligosaccharide mixture (B-GOS) on gut microbiota, immune parameters and metabonomics in elderly persons.
Topics: Aged; Aged, 80 and over; Aging; Bacteria; Bacteroides; Bifidobacterium; Biomarkers; C-Reactive Prote | 2015 |
Acute resistance exercise with blood flow restriction in elderly hypertensive women: haemodynamic, rating of perceived exertion and blood lactate.
Topics: Age Factors; Aged; Aging; Biomarkers; Cross-Over Studies; Female; Hemodynamics; Humans; Hypertension | 2018 |
Treatment of HIV lipoatrophy and lipoatrophy of aging with poly-L-lactic acid: a prospective 3-year follow-up study.
Topics: Aged; Aging; Cellulose; Cohort Studies; Female; Follow-Up Studies; HIV-Associated Lipodystrophy Synd | 2008 |
Growth, training response and health in Standardbred yearlings fed a forage-only diet.
Topics: Aging; Animal Nutritional Physiological Phenomena; Animals; Diet; Eating; Heart Rate; Horses; Lactic | 2013 |
Oxidation rate of exogenous carbohydrate during exercise is higher in boys than in men.
Topics: Adipose Tissue; Adult; Aging; Blood Glucose; Child; Dietary Carbohydrates; Energy Metabolism; Exerci | 2003 |
Aging and the exercise pressor reflex in humans.
Topics: Adult; Age Factors; Aged; Aging; Blood Flow Velocity; Blood Gas Analysis; Blood Pressure; Exercise; | 2003 |
The effect of training in male prepubertal and pubertal monozygotic twins.
Topics: Adaptation, Physiological; Adolescent; Age Factors; Aging; Anaerobic Threshold; Body Mass Index; Chi | 2003 |
Reproducibility of the lactate stress test.
Topics: Adult; Aged; Aged, 80 and over; Aging; Exercise Test; Female; Humans; Lactic Acid; Male; Middle Aged | 2003 |
Modeling the blood lactate kinetics at maximal short-term exercise conditions in children, adolescents, and adults.
Topics: Adolescent; Adult; Aging; Child; Computer Simulation; Humans; Kinetics; Lactic Acid; Male; Metabolic | 2005 |
Safety and efficacy of poly-L-lactic acid in HIV lipoatrophy and lipoatrophy of aging.
Topics: Adult; Aged; Aged, 80 and over; Aging; Case-Control Studies; Drug-Related Side Effects and Adverse R | 2007 |
Influence of age and pubertal status on substrate utilization during exercise with and without carbohydrate intake in healthy boys.
Topics: Adolescent; Aging; Beverages; Bicycling; Blood Glucose; Child; Dietary Carbohydrates; Double-Blind M | 2007 |
Physiological determinants of 10-km performance in highly trained female runners of different ages.
Topics: Adult; Aging; Anaerobic Threshold; Body Composition; Body Weight; Energy Metabolism; Female; Humans; | 1995 |
Is metformin safe enough for ageing type 2 diabetic patients?
Topics: Aged; Aged, 80 and over; Aging; Anthropometry; Blood Glucose; Diabetes Mellitus, Type 2; Drug Therap | 1996 |
Exercise-induced VA/Q inequality in subjects with prior high-altitude pulmonary edema.
Topics: Adult; Aging; Altitude; Altitude Sickness; Blood Gas Analysis; Cardiac Output; Energy Metabolism; Ex | 1996 |
Reduced leg blood flow during dynamic exercise in older endurance-trained men.
Topics: Adult; Aged; Aging; Blood Gas Analysis; Blood Pressure; Catecholamines; Energy Metabolism; Exercise; | 1998 |
Aging alters regional multichemical profile of the human brain: an in vivo 1H-MRS study of young versus middle-aged subjects.
Topics: Adult; Age Factors; Aging; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Female; gamma-A | 2001 |
Aging alters the multichemical networking profile of the human brain: an in vivo (1)H-MRS study of young versus middle-aged subjects.
Topics: Adult; Aging; Analysis of Variance; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Female | 2001 |
Acid-base balance during repeated cycling sprints in boys and men.
Topics: Acid-Base Equilibrium; Adult; Aging; Arteries; Bicarbonates; Bicycling; Blood; Carbon Dioxide; Child | 2002 |
Loss of preconditioning by attenuated activation of myocardial ATP-sensitive potassium channels in elderly patients undergoing coronary angioplasty.
Topics: Adult; Aged; Aging; Angioplasty, Balloon, Coronary; ATP-Binding Cassette Transporters; Chest Pain; C | 2002 |
Hormonal responses to exercise during moderate cold exposure in young vs. middle-age subjects.
Topics: Adult; Aging; Arginine Vasopressin; Atrial Natriuretic Factor; Bicycling; Catecholamines; Cold Tempe | 1992 |
228 other studies available for lactic acid and Aging
| Article | Year |
|---|---|
Aging astrocytes metabolically support aging axon function by proficiently regulating astrocyte-neuron lactate shuttle.
Topics: Aging; Animals; Astrocytes; Axons; Glucose; Glycogen; Lactic Acid; Mice; Neurons | 2022 |
H3K18 lactylation of senescent microglia potentiates brain aging and Alzheimer's disease through the NFκB signaling pathway.
Topics: Aging; Alzheimer Disease; Animals; Brain; Histones; Interleukin-6; Interleukin-8; Lactic Acid; Mice; | 2023 |
Physiological Profile of a 59-Year-Old Male World Record Holder Marathoner.
Topics: Aging; Cardiorespiratory Fitness; Energy Metabolism; Heart Rate; Humans; Lactic Acid; Male; Middle A | 2020 |
Cell-to-cell lactate shuttle operates in heart and is important in age-related heart failure.
Topics: Aging; Animals; Cell Cycle; Cell Line; Fibroblasts; Heart Failure; Lactic Acid; Mice; Myocardium; My | 2020 |
Importance of dimensional changes on glycolytic metabolism during growth.
Topics: Adolescent; Adolescent Development; Aging; Body Weight; Child; Exercise; Glycolysis; Humans; Lactic | 2020 |
Effect of aging on mitochondria and metabolism of bovine granulosa cells.
Topics: Adenosine Triphosphate; Aging; Animals; Cattle; Cell Proliferation; Cell Survival; Culture Media; DN | 2020 |
Gut cytokines modulate olfaction through metabolic reprogramming of glia.
Topics: Aging; Animals; Avoidance Learning; Cytokines; Drosophila melanogaster; Drosophila Proteins; Female; | 2021 |
Effects of age and glucose levels on lactate levels in cerebrospinal fluid examination of neurodegenerative diseases.
Topics: Adult; Aged; Aged, 80 and over; Aging; Cerebrospinal Fluid Proteins; Female; Glucose; Humans; Lactic | 2017 |
Upregulation of mitochondrial NAD
Topics: Aging; Animals; Brain Neoplasms; Cell Differentiation; Cell Line, Tumor; Colony-Forming Units Assay; | 2017 |
Metabolic and hormonal responses to different resistance training systems in elderly men.
Topics: Aged; Aging; Biomarkers; Blood Glucose; Growth Hormone; Humans; Hydrocortisone; Lactic Acid; Male; M | 2018 |
Age-dependent physiological dynamics in acid-base balance, electrolytes, and blood metabolites in growing goats.
Topics: Acid-Base Equilibrium; Aging; Animals; Animals, Newborn; Blood Glucose; Electrolytes; Female; Goats; | 2017 |
The Protective Effect of Melatonin Against Age-Associated, Sarcopenia-Dependent Tubular Aggregate Formation, Lactate Depletion, and Mitochondrial Changes.
Topics: Aging; Animals; Female; Lactic Acid; Magnetic Resonance Imaging; Melatonin; Mice; Mice, Inbred C57BL | 2018 |
Age related rise in lactate and its correlation with lactate dehydrogenase (LDH) status in post-mitochondrial fractions isolated from different regions of brain in mice.
Topics: Aging; Animals; Brain; Enzyme Activation; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase | 2018 |
Biospectroscopic Imaging Provides Evidence of Hippocampal Zn Deficiency and Decreased Lipid Unsaturation in an Accelerated Aging Mouse Model.
Topics: Aging; Animals; CA3 Region, Hippocampal; Corpus Callosum; Dementia; Disease Models, Animal; Fatty Ac | 2018 |
Physiological responses in different intensities of resistance exercise - Critical load and the effects of aging process.
Topics: Adult; Aged; Aging; Exercise; Exercise Test; Heart Rate; Humans; Lactic Acid; Male; Muscle Fatigue; | 2019 |
The human central nervous system discharges carbon dioxide and lactic acid into the cerebrospinal fluid.
Topics: Adult; Aged; Aged, 80 and over; Aging; Blood Gas Analysis; Carbon Dioxide; Central Nervous System; C | 2019 |
Age- and gender-related metabonomic alterations in striatum and cerebellar cortex in rats.
Topics: Aging; Animals; Cerebellar Cortex; Corpus Striatum; Creatine; Female; Glutamic Acid; Inositol; Lacti | 2013 |
The neural interaction between the arterial baroreflex and muscle metaboreflex is preserved in older men.
Topics: Adult; Aging; Baroreflex; Exercise; Hand Strength; Humans; Lactic Acid; Male; Middle Aged; Muscle, S | 2013 |
Identification of anaerobic threshold by analysis of heart rate variability during discontinuous dynamic and resistance exercise protocols in healthy older men.
Topics: Adaptation, Physiological; Age Factors; Aged; Aging; Anaerobic Threshold; Biomarkers; Blood Pressure | 2014 |
Immunogenetic responses in calves to intranasal delivery of bovine respiratory syncytial virus (BRSV) epitopes encapsulated in poly (DL-lactide-co-glycolide) microparticles.
Topics: Administration, Intranasal; Aging; Animals; Antibodies, Viral; Cattle; Epitopes; Female; Immunity, M | 2013 |
Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: implication for bioenergetic intervention.
Topics: Adaptation, Physiological; Aging; Alzheimer Disease; Animals; Astrocytes; Biological Transport, Acti | 2013 |
Deleterious effects of aggressive rapid crystalloid resuscitation on treatment of hyperinflammatory response and lung injury induced by hemorrhage in aging rats.
Topics: Acute Lung Injury; Aging; Animals; Blood Glucose; Blood Pressure; Body Temperature; Bronchoalveolar | 2014 |
Regional variations and age-related changes detected with magnetic resonance spectroscopy in the brain of healthy dogs.
Topics: Aging; Animals; Aspartic Acid; Brain; Choline; Creatine; Dogs; Female; Lactic Acid; Magnetic Resonan | 2014 |
M(o)TOR of pseudo-hypoxic state in aging: rapamycin to the rescue.
Topics: Aging; Animals; Antibiotics, Antineoplastic; Cell Hypoxia; Cell Line; Cell Proliferation; Cellular S | 2014 |
Physiological characteristics of an aging Olympic athlete.
Topics: Adult; Aging; Athletic Performance; Cardiovascular Physiological Phenomena; Echocardiography; Effici | 2014 |
The safety and efficacy of poly-L-lactic acid on sunken cheeks in Asians.
Topics: Adipose Tissue; Adult; Aging; Asian People; Atrophy; Biocompatible Materials; Cheek; Contusions; Cos | 2014 |
African drumming: a holistic approach to reducing stress and improving health?
Topics: Adult; Aging; Anxiety; Blood Pressure; Exercise; Female; Heart Rate; Holistic Health; Humans; Hypert | 2014 |
Late gestation under- and overnutrition have differential impacts when combined with a post-natal obesogenic diet on glucose-lactate-insulin adaptations during metabolic challenges in adolescent sheep.
Topics: Adaptation, Physiological; Aging; Animals; Diet; Fasting; Female; Glucose; Hyperglycemia; Insulin; L | 2015 |
Age-related metabolic fatigue during low glucose conditions in rat hippocampus.
Topics: Aging; Animals; CA1 Region, Hippocampal; Glucose; Glycogen; Hypoglycemia; In Vitro Techniques; Lacti | 2015 |
Aging's effects on marathon performance insights from the New York City race.
Topics: Adult; Aged; Aged, 80 and over; Aging; Competitive Behavior; Female; Humans; Lactic Acid; Male; Midd | 2015 |
Age-dependent neuromuscular impairment in prion protein knockout mice.
Topics: Action Potentials; Adenosine Triphosphatases; Aging; Animals; Citrate (si)-Synthase; Disease Models, | 2016 |
L-Lactate Protects Skin Fibroblasts against Aging-Associated Mitochondrial Dysfunction via Mitohormesis.
Topics: Aging; AMP-Activated Protein Kinases; Animals; Cells, Cultured; DNA, Mitochondrial; Fibroblasts; Glu | 2015 |
Methylphenidate increases glucose uptake in the brain of young and adult rats.
Topics: Aging; Animals; Brain; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Glucose; | 2015 |
Pyruvate to Lactate Metabolic Changes during Neurodevelopment Measured Dynamically Using Hyperpolarized 13C Imaging in Juvenile Murine Brain.
Topics: Adolescent; Aging; Animals; Brain; Humans; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonan | 2016 |
Aerobic Glycolysis in the Frontal Cortex Correlates with Memory Performance in Wild-Type Mice But Not the APP/PS1 Mouse Model of Cerebral Amyloidosis.
Topics: Aerobiosis; Aging; Amyloid beta-Protein Precursor; Amyloidosis; Animals; Astrocytes; Brain Chemistry | 2016 |
Age Related Bioenergetics Profiles in Isolated Rat Cardiomyocytes Using Extracellular Flux Analyses.
Topics: Aging; Animals; Animals, Newborn; Carbon Dioxide; Fatty Acids; Female; Glycolysis; Lactic Acid; Meta | 2016 |
Age-related impairments in skeletal muscle PDH phosphorylation and plasma lactate are indicative of metabolic inflexibility and the effects of exercise training.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aging; Blood Glucose; Exercise; Female; Glucose Clamp T | 2016 |
A new model of short acceleration-based training improves exercise performance in old mice.
Topics: Acceleration; Aging; Animals; Exercise Test; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Mitochondr | 2017 |
Age-related changes in skeletal muscle composition: A pilot nuclear magnetic resonance spectroscopy study in mice.
Topics: Acetates; Aging; Animals; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred BAL | 2017 |
A rapid and sensitive screening system for human type I collagen with the aim of discovering potent anti-aging or anti-fibrotic compounds.
Topics: Aging; Ascorbic Acid; Cell Line; Citric Acid; Collagen Type I; Drug Evaluation, Preclinical; Enzyme- | 2008 |
Caloric restriction counteracts age-related changes in the activities of sorbitol metabolizing enzymes from mouse liver.
Topics: Age Factors; Aging; Aldehyde Reductase; Animals; Caloric Restriction; Fructose; Glucose; L-Iditol 2- | 2009 |
Role of {alpha}1-adrenergic vasoconstriction in the regulation of skeletal muscle blood flow with advancing age.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; | 2009 |
Evidence for differential regulation of lactate metabolic properties in aged and unloaded rat skeletal muscle.
Topics: Aging; Animals; Blotting, Western; Hindlimb; Lactic Acid; Male; Monocarboxylic Acid Transporters; Mu | 2009 |
Activation of c-Jun-N-terminal kinase and decline of mitochondrial pyruvate dehydrogenase activity during brain aging.
Topics: Adenosine Triphosphate; Aging; Anaerobiosis; Animals; Brain; Catalytic Domain; Glycolysis; JNK Mitog | 2009 |
Copper deficiency alters the neurochemical profile of developing rat brain.
Topics: Aging; Animals; Ascorbic Acid; Aspartic Acid; Brain; Brain Chemistry; Cerebellum; Citric Acid; Coppe | 2009 |
Early metabolic reactivation versus antioxidant therapy after a traumatic spinal cord injury in adult rats.
Topics: Acute Disease; Aging; Animals; Antioxidants; Catalase; Creatine Kinase; Female; Lactic Acid; Lipid P | 2010 |
Determination of the lactate threshold and maximal blood lactate steady state intensity in aged rats.
Topics: Aging; Analysis of Variance; Animals; Lactic Acid; Male; Models, Statistical; Physical Conditioning, | 2009 |
Metabolic aspects of neonatal rat islet hypoxia tolerance.
Topics: Adenosine Triphosphate; Aging; Animals; Animals, Newborn; Calcium; Cells, Cultured; Cyclic AMP; Gluc | 2010 |
Basal forebrain lactate release and promotion of cortical arousal during prolonged waking is attenuated in aging.
Topics: Age Factors; Aging; Analysis of Variance; Animals; Arousal; Cerebral Cortex; Chromatography, High Pr | 2009 |
Age-related differences in repeated-sprint ability in highly trained youth football players.
Topics: Adolescent; Aging; Athletes; Athletic Performance; Child; Exercise Test; Football; Humans; Lactic Ac | 2009 |
Effects of glyoxal or methylglyoxal on the metabolism of amino acids, lactate, glucose and acetate in the cerebral cortex of young and adult rats.
Topics: Acetates; Aging; Amino Acids; Animals; Carbon Dioxide; Central Nervous System Agents; Cerebral Corte | 2010 |
Effects of resistance exercise and protein ingestion on blood leukocytes and platelets in young and older men.
Topics: Adult; Aged; Aging; Exercise; Humans; Isometric Contraction; Lactic Acid; Leukocyte Count; Male; Mid | 2010 |
Postexercise heart rate recovery in children: relationship with power output, blood pH, and lactate.
Topics: Acidosis, Lactic; Adolescent; Age Factors; Aging; Bicycling; Biomarkers; Child; Exercise; Glycolysis | 2010 |
Effects of combined strength and endurance training on treadmill load carrying walking performance in aging men.
Topics: Adaptation, Physiological; Aged; Aging; Body Mass Index; Exercise Test; Forearm; Heart Rate; Humans; | 2010 |
Exercise test and glucose homeostasis in rats treated with alloxan during the neonatal period or fed a high calorie diet.
Topics: Age Factors; Aging; Animals; Animals, Newborn; Biomarkers; Blood Glucose; Diabetes Mellitus, Experim | 2009 |
A new type of Schwann cell graft transplantation to promote optic nerve regeneration in adult rats.
Topics: Aging; Animals; Axons; Cell Line; Ciliary Neurotrophic Factor; Fluorescent Antibody Technique; GAP-4 | 2010 |
High brain lactate is a hallmark of aging and caused by a shift in the lactate dehydrogenase A/B ratio.
Topics: Aging; Animals; Brain; DNA, Mitochondrial; Gene Expression Regulation, Enzymologic; Isoenzymes; L-La | 2010 |
Age related decreases in thermoregulation and cardiovascular function in horses.
Topics: Aging; Animals; Blood Proteins; Body Temperature Regulation; Dehydration; Female; Heart Rate; Hemato | 2010 |
D-galactose effectiveness in modeling aging and therapeutic antioxidant treatment in mice.
Topics: Aging; Animals; Antioxidants; Female; Galactose; Lactic Acid; Maze Learning; Memory; Mice; Mice, Inb | 2010 |
High brain lactate is not caused by a shift in the lactate dehydrogenase A/B ratio.
Topics: Aging; Animals; Biomarkers; Brain; Cytosol; Isoenzymes; Kinetics; L-Lactate Dehydrogenase; Lactic Ac | 2011 |
Comparison of metabolic profiling of cyanidin-3-O-galactoside and extracts from blueberry in aged mice.
Topics: Aging; Animals; Anthocyanins; Blueberry Plants; Brain Chemistry; Choline; Fruit; Galactosides; gamma | 2011 |
Relationship between the effect of dietary fat on swimming endurance and energy metabolism in aged mice.
Topics: Aging; Animals; Carnitine O-Palmitoyltransferase; Dietary Fats; Energy Metabolism; Fatigue; Fatty Ac | 2011 |
Aging and factors related to running economy.
Topics: Adolescent; Adult; Age Factors; Aged; Aging; Athletic Performance; Body Composition; Cross-Sectional | 2011 |
Injectable fillers for volume replacement in the aging face.
Topics: Aging; Biocompatible Materials; Cheek; Cosmetic Techniques; Durapatite; Eyelids; Face; Humans; Hyalu | 2012 |
Effects of lactate on the early visual cortex of non-human primates, investigated by pharmaco-MRI and neurochemical analysis.
Topics: Aging; Animals; Brain Chemistry; Cerebrovascular Circulation; Data Interpretation, Statistical; Elec | 2012 |
[Spiroergometric reference values for the sociomedical assessment of performance in adults aged over 60 years].
Topics: Aged; Aging; Ergometry; Female; Germany; Humans; Lactic Acid; Male; Middle Aged; Oxygen Consumption; | 2012 |
The cycling physiology of Miguel Indurain 14 years after retirement.
Topics: Aging; Bicycling; Biomarkers; Body Composition; Exercise Test; Heart Rate; Humans; Lactic Acid; Male | 2012 |
Cerebrospinal fluid glucose and lactate: age-specific reference values and implications for clinical practice.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Blood Glucose; Child; Child, Preschool; Glucose; | 2012 |
Aralar mRNA and protein levels in neurons and astrocytes freshly isolated from young and adult mouse brain and in maturing cultured astrocytes.
Topics: Aging; Animals; Aspartic Acid; Astrocytes; Brain; Cell Separation; Cells, Cultured; Cellular Senesce | 2012 |
Cerebral perfusion, oxygenation and metabolism during exercise in young and elderly individuals.
Topics: Adult; Aged; Aging; Blood Pressure; Brain; Cardiac Output; Cerebral Arteries; Cerebrovascular Circul | 2013 |
Metabolic characteristics of the faecal microflora in humans from three age groups.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Bacteria; Child; Child, Preschool; Enzymes; Fatty | 2002 |
Effects of age and recovery duration on peak power output during repeated cycling sprints.
Topics: Adolescent; Adult; Aging; Bicycling; Child; Fatigue; Humans; Lactic Acid; Male; Oxygen Consumption; | 2002 |
Modulation by polyamines of gamma-glutamyl transpeptidase activity and lactate production in cultured Sertoli cells from immature and adult regressed golden hamster.
Topics: Aging; Animals; Cells, Cultured; Cricetinae; Follicle Stimulating Hormone; gamma-Glutamyltransferase | 2002 |
Impact of aging on substrate metabolism by the human heart.
Topics: Adult; Aged; Aging; Blood Glucose; Fatty Acids; Female; Humans; Insulin; Lactic Acid; Male; Middle A | 2003 |
Impact of aging on substrate metabolism by the human heart.
Topics: Adult; Aged; Aging; Blood Glucose; Fatty Acids; Female; Humans; Insulin; Lactic Acid; Male; Middle A | 2003 |
Impact of aging on substrate metabolism by the human heart.
Topics: Adult; Aged; Aging; Blood Glucose; Fatty Acids; Female; Humans; Insulin; Lactic Acid; Male; Middle A | 2003 |
Impact of aging on substrate metabolism by the human heart.
Topics: Adult; Aged; Aging; Blood Glucose; Fatty Acids; Female; Humans; Insulin; Lactic Acid; Male; Middle A | 2003 |
A test to assess the mechanical power sustainable during everyday activities in older people.
Topics: Activities of Daily Living; Aged; Aging; Exercise Test; Female; Heart Rate; Humans; Lactic Acid; Mal | 2003 |
Influence of age and caloric restriction on liver glycolytic enzyme activities and metabolite concentrations in mice.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Aging; Animals; Caloric Restriction; Fructosediphosphates; Glu | 2003 |
Inhibitory effect of menaquinone-7 (vitamin K2) on the bone-resorbing factors-induced bone resorption in elderly female rat femoral tissues in vitro.
Topics: Aging; Animals; Bone and Bones; Bone Resorption; Calcium; Cells, Cultured; Culture Media; Dinoprosto | 2003 |
Effect of age and endurance training on the capacity for epinephrine-stimulated gluconeogenesis in rat hepatocytes.
Topics: Aging; Animals; Epinephrine; Gluconeogenesis; Hepatocytes; In Vitro Techniques; Kinetics; Lactic Aci | 2003 |
Impact of aging on myocardial metabolic response to dobutamine.
Topics: Adrenergic beta-Agonists; Adult; Aged; Aging; Blood Glucose; Blood Pressure; Coronary Circulation; D | 2003 |
Age-related changes in cerebral lactate metabolism in sleep-disordered breathing.
Topics: Adult; Aged; Aging; Apnea; Body Mass Index; Cerebral Cortex; Female; Humans; Lactic Acid; Magnetic R | 2003 |
[Synaptic utilization of lactate/pyruvate and neural function in the aging].
Topics: Aging; Animals; Brain; Glucose; Guinea Pigs; Hippocampus; Lactic Acid; Neurons; Pyruvic Acid; Synaps | 2003 |
Maximal lactate steady state declines during the aging process.
Topics: Adult; Aged; Aging; Anaerobic Threshold; Body Composition; Citrate (si)-Synthase; Cross-Sectional St | 2003 |
Exercise responses of elderly patients with diastolic versus systolic heart failure.
Topics: Aged; Aging; Anaerobic Threshold; Diastole; Exercise; Exercise Tolerance; Female; Heart Failure; Hum | 2003 |
HEART RATE, ARTERIAL LACTATE CONCENTRATION AND OXYGEN UPTAKE DURING EXERCISE IN OLD MEN COMPARED WITH YOUNG MEN.
Topics: Aging; Blood Chemical Analysis; Dyspnea; Exercise Test; Fatigue; Geriatrics; Heart; Heart Rate; Huma | 1964 |
The effect of oligaemia on the content of glycogen and lactic acid in the brain of the rat during ontogeny.
Topics: Aging; Animals; Brain; Glycogen; Glycogenolysis; Lactates; Lactic Acid; Neurochemistry; Rats | 1962 |
Developmental switch in brain nutrient transporter expression in the rat.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Blood Glucose; Blood-Brain Barrier; Brain; Brain Chemistry; C | 2003 |
Stimulus-induced brain lactate: effects of aging and prolonged wakefulness.
Topics: Adult; Age Factors; Aged; Aging; Brain; Cognition; Female; Humans; Lactic Acid; Magnetic Resonance S | 2004 |
Mitochondrial function in turkey skeletal muscle--impact on meat quality.
Topics: Acidosis; Aging; Animals; Body Composition; Glycolysis; Histocytochemistry; Hydrogen-Ion Concentrati | 2004 |
Dying to see.
Topics: Acquired Immunodeficiency Syndrome; Aged; Aging; Alzheimer Disease; Animals; Apoptosis; Cataract; Ey | 2004 |
Skeletal muscle aging in F344BN F1-hybrid rats: II. Improved contractile economy in senescence helps compensate for reduced ATP-generating capacity.
Topics: Adenosine Triphosphate; Aging; Animals; Hindlimb; Lactic Acid; Male; Muscle Contraction; Muscle, Ske | 2004 |
Improved muscular efficiency displayed as Tour de France champion matures.
Topics: Adaptation, Physiological; Adult; Aging; Bicycling; Body Constitution; Energy Metabolism; France; Hu | 2005 |
Differential effects of alcohol upon gluconeogenesis from lactate in young and old hepatocytes.
Topics: Aging; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Ethanol; Gluconeogenesis; Hepatoc | 2005 |
Severe cognitive impairment correlates with higher cerebrospinal fluid levels of lactate and pyruvate in a canine model of senile dementia.
Topics: Aging; Alzheimer Disease; Animals; Behavior, Animal; Biomarkers; Brain Chemistry; Cerebrospinal Flui | 2005 |
Preparation of gelatin microspheres containing lactic acid--effect of cross-linking on drug release.
Topics: Aging; Cross-Linking Reagents; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Gelatin | 2005 |
Age-dependent reduction of cortical contusion volume by ketones after traumatic brain injury.
Topics: Age Factors; Aging; Animals; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Energy Metabol | 2005 |
Anatomical parameters of cardiopulmonary system in three different lines of chickens: further evidence for involvement in ascites syndrome.
Topics: Aging; Animals; Ascites; Body Weight; Cardiovascular System; Chickens; Genetic Predisposition to Dis | 2005 |
Contraindications can damage your health--is metformin a case in point?
Topics: Acidosis, Lactic; Aging; Contraindications; Diabetes Mellitus, Type 2; Heart Diseases; Humans; Hypog | 2005 |
Age-related effects on fitness performance in elite-level soccer referees.
Topics: Adult; Aging; Exercise Test; Humans; Lactic Acid; Male; Middle Aged; Oxygen Consumption; Physical Fi | 2005 |
Metabolic remodeling in the aging heart.
Topics: Aging; Animals; Citrate (si)-Synthase; Fatty Acids; Glucose; Heart; In Vitro Techniques; L-Lactate D | 2006 |
Effects of age and recovery duration on performance during multiple treadmill sprints.
Topics: Adult; Aging; Analysis of Variance; Child; Fatigue; Humans; Lactic Acid; Male; Oxygen Consumption; P | 2006 |
Age-related differences in myocardial hydrogen ion buffering during ischemia.
Topics: Aging; Animals; Animals, Newborn; Glycolysis; Heart Septum; Heart Ventricles; Histidine; Hydrogenati | 2006 |
C3a levels and occurrence of subdermal vascular thrombosis are age-related in deep second-degree burn wounds.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Blood Glucose; Burns; Complement C3a; Glycerol; H | 2006 |
Performance during consecutive days of laboratory time-trials in young and veteran cyclists.
Topics: Adolescent; Adult; Age Factors; Aging; Analysis of Variance; Bicycling; Biomarkers; Clinical Laborat | 2006 |
Assessment of post-competition peak blood lactate in male and female master swimmers aged 40-79 years and its relationship with swimming performance.
Topics: Adult; Aged; Aging; Algorithms; Anthropometry; Body Composition; Body Height; Body Weight; Bone and | 2007 |
Serial blood lactate concentrations in systemically ill dogs.
Topics: Aging; Animals; Body Weight; Dog Diseases; Dogs; Female; Lactic Acid; Male; Reference Values; Sex Ch | 2007 |
The modified D-max is a valid lactate threshold measurement in veteran cyclists.
Topics: Adult; Aging; Anaerobic Threshold; Bicycling; Biometry; Exercise Test; Female; Heart Rate; Humans; L | 2008 |
O2 uptake kinetics, pyruvate dehydrogenase activity, and muscle deoxygenation in young and older adults during the transition to moderate-intensity exercise.
Topics: Adult; Aged; Aging; Enzyme Activation; Exercise; Hemoglobins; Humans; Kinetics; Lactic Acid; Mitocho | 2008 |
Overexpression of pyruvate dehydrogenase kinase 4 in heart perturbs metabolism and exacerbates calcineurin-induced cardiomyopathy.
Topics: Aging; Animals; Blotting, Western; Calcineurin; Cardiomyopathies; Humans; Lactic Acid; Mice; Mice, T | 2008 |
Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging.
Topics: Absorptiometry, Photon; Adult; Aged; Aging; Algorithms; Amino Acids, Essential; Anabolic Agents; Blo | 2008 |
Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging.
Topics: Absorptiometry, Photon; Adult; Aged; Aging; Algorithms; Amino Acids, Essential; Anabolic Agents; Blo | 2008 |
Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging.
Topics: Absorptiometry, Photon; Adult; Aged; Aging; Algorithms; Amino Acids, Essential; Anabolic Agents; Blo | 2008 |
Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging.
Topics: Absorptiometry, Photon; Adult; Aged; Aging; Algorithms; Amino Acids, Essential; Anabolic Agents; Blo | 2008 |
Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging.
Topics: Absorptiometry, Photon; Adult; Aged; Aging; Algorithms; Amino Acids, Essential; Anabolic Agents; Blo | 2008 |
Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging.
Topics: Absorptiometry, Photon; Adult; Aged; Aging; Algorithms; Amino Acids, Essential; Anabolic Agents; Blo | 2008 |
Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging.
Topics: Absorptiometry, Photon; Adult; Aged; Aging; Algorithms; Amino Acids, Essential; Anabolic Agents; Blo | 2008 |
Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging.
Topics: Absorptiometry, Photon; Adult; Aged; Aging; Algorithms; Amino Acids, Essential; Anabolic Agents; Blo | 2008 |
Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging.
Topics: Absorptiometry, Photon; Adult; Aged; Aging; Algorithms; Amino Acids, Essential; Anabolic Agents; Blo | 2008 |
Muscular metabolism in aged rats under exhaustive exercise: effect of a modified alkaline supplementation.
Topics: Acetylcarnitine; Aging; Animals; Blood Gas Analysis; Creatine Kinase; Dietary Supplements; Glycogen; | 2008 |
Potential ergogenic effects of L-arginine against oxidative and inflammatory stress induced by acute exercise in aging rats.
Topics: Aging; Animals; Arginine; Biomarkers; Dietary Supplements; Inflammation; Kidney; Lactic Acid; Liver; | 2008 |
Early and sustained alterations in cerebral metabolism after traumatic brain injury in immature rats.
Topics: Aging; Alanine; Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Injuries; Cell Respiration; C | 2008 |
Intermittent ischemia but not ischemic preconditioning is effective in restoring bile flow after ischemia reperfusion injury in the livers of aged rats.
Topics: Aging; Animals; Bile; Bilirubin; Hepatocytes; Ischemic Preconditioning; Lactic Acid; Liver; Liver Fu | 2009 |
[Effect of bran diet on organic acids in the gastrointestinal tract and apparent digestibility in weanling piglets].
Topics: Aging; Animals; Cecum; Colon; Dietary Fiber; Digestion; Digestive System; Fatty Acids, Volatile; Gas | 1984 |
Changes in work tolerance associated with metabolic and physiological adjustment to moderate and severe iron deficiency anemia.
Topics: Adaptation, Physiological; Aging; Anemia, Hypochromic; Animals; Bloodletting; Electron Transport Com | 1982 |
Glucose uptake and insulin sensitivity in rat muscle: changes during 3-96 weeks of age.
Topics: Aging; Animals; Biological Transport; Deoxyglucose; Dose-Response Relationship, Drug; Glucose; Glyco | 1983 |
Age-related changes in the metabolism of tendon cells.
Topics: Aging; Alanine; Anaerobiosis; Animals; Carbon Radioisotopes; Glucose; Glycolysis; Lactates; Lactic A | 1981 |
The effect of ageing and exercise on skeletal muscle function.
Topics: Adenosine Triphosphate; Aging; Animals; Calcium; Glycogen; In Vitro Techniques; Lactates; Lactic Aci | 1984 |
Endurance training in older men and women II. Blood lactate response to submaximal exercise.
Topics: Aged; Aging; Body Composition; Female; Heart Rate; Humans; Lactates; Lactic Acid; Male; Middle Aged; | 1984 |
Perinatal changes of fructose 2,6-bisphosphate in the rat liver.
Topics: Aging; Animals; Blood Glucose; Female; Fetus; Fructosediphosphates; Glucose; Hexosediphosphates; Lac | 1983 |
Influence of ageing on glucose homeostasis.
Topics: Adult; Aged; Aging; Blood Glucose; C-Peptide; Fatty Acids, Nonesterified; Glucose; Glucose Tolerance | 1982 |
Influence of age upon the cerebral metabolic changes induced by acute hypoxia on the synaptosomes from dog brain.
Topics: Adenine Nucleotides; Aging; Animals; Dihydroergotoxine; Dogs; Female; Hypoxia; Lactates; Lactic Acid | 1982 |
Brown adipose tissue metabolism in hypothalamic-obese rats.
Topics: Adipose Tissue, Brown; Aging; Animals; Diet; Fatty Acids; Glucose; Hypothalamus; Lactates; Lactic Ac | 1983 |
Development of gluconeogenesis in isolated hepatocytes from the rabbit.
Topics: Aging; Animals; Animals, Newborn; Cytosol; Fatty Acids; Gluconeogenesis; Glycogen; Lactates; Lactic | 1983 |
Age-related changes in rat adipose tissue in response to fasting: protein, lactate and pyruvate levels.
Topics: Adipose Tissue; Aging; Animals; Fasting; Lactates; Lactic Acid; Male; NAD; Proteins; Pyruvates; Pyru | 1983 |
Lactate and pyruvate content of the human cisternal cerebrospinal fluid. Normal values, age and sex dependency, correlations with glucose concentrations.
Topics: Adolescent; Adult; Aged; Aging; Blood Glucose; Cisterna Magna; Female; Humans; Lactates; Lactic Acid | 1983 |
Elevation of cerebrospinal fluid lactate with aging in subjects with normal blood oxygen saturations.
Topics: Adult; Aging; Humans; Lactates; Lactic Acid; Male; Middle Aged; Oximetry; Oxygen | 1982 |
The glyoxalase system in rat blood.
Topics: Aging; Animals; Body Weight; Erythrocytes; Kinetics; Lactates; Lactic Acid; Lactoylglutathione Lyase | 1982 |
Fatty acid synthesis from lactate in growing cattle.
Topics: Acetates; Adipose Tissue; Aging; Animals; ATP Citrate (pro-S)-Lyase; Cattle; Fatty Acids; Glucosepho | 1981 |
Age-related alterations in energy metabolism contribute to the increased vulnerability of the aging brain to anoxic damage.
Topics: Adenosine Triphosphate; Aging; Animals; Brain; Cell Hypoxia; Energy Metabolism; Glucose; Hippocampus | 1995 |
Age-dependent neurotoxicity of striatal lesions produced by aminooxyacetic acid: quantitative in vitro 1H NMR spectroscopic studies.
Topics: Aging; Alanine; Animals; Aspartic Acid; Corpus Striatum; Creatine; Energy Metabolism; gamma-Aminobut | 1995 |
Age-dependent striatal excitotoxic lesions produced by the endogenous mitochondrial inhibitor malonate.
Topics: Adenosine Triphosphate; Aging; Animals; Corpus Striatum; Dizocilpine Maleate; gamma-Aminobutyric Aci | 1993 |
Effect of dietary vitamin E supplementation on macrophage metabolism during ageing. Study in rats fed fat-rich diets during ageing.
Topics: Aging; Animals; Cell Count; Citrate (si)-Synthase; Dietary Fats, Unsaturated; Fatty Acids, Unsaturat | 1994 |
Effect of growth on efficiency and fatigue in extensor digitorum longus muscle of the rat.
Topics: Adenosine Triphosphate; Aging; Animals; Lactates; Lactic Acid; Male; Muscle Contraction; Muscle Deve | 1994 |
Long-term effects of cafeteria diet feeding on young Wistar rats.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Blood Glucose; Body Weight; Diet; Female; Glycerol; Hydroxybu | 1994 |
Role of norepinephrine in hepatic gluconeogenesis: evidence of aging and training effects.
Topics: Aging; Animals; Gluconeogenesis; Glucose; Glycogen; Glycogen Synthase; Lactates; Lactic Acid; Liver; | 1994 |
Glycolysis abnormalities in fibromyalgia.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Adult; Aged; Aged, 80 and over; Aging; Diphosphoglyc | 1994 |
Effects of aerobic exercise conditioning at intensities corresponding to lactate threshold in the elderly.
Topics: Aged; Aging; Anaerobic Threshold; Blood Pressure; Body Composition; Electrocardiography; Exercise; F | 1993 |
Insulin reduces basal release of atrial natriuretic factor by isolated, perfused neonatal pig hearts.
Topics: Aging; Animals; Animals, Newborn; Atrial Natriuretic Factor; Glucose; Heart; Insulin; Lactates; Lact | 1993 |
Exercise conditioning in older coronary patients. Submaximal lactate response and endurance capacity.
Topics: Aged; Aged, 80 and over; Aging; Coronary Disease; Female; Humans; Lactates; Lactic Acid; Male; Middl | 1993 |
Glucose use in neonatal rabbit hearts reperfused after global ischemia.
Topics: Aging; Animals; Animals, Newborn; Coronary Disease; Dichloroacetic Acid; Female; Glucose; Glycolysis | 1993 |
Age-dependent vulnerability of the striatum to the mitochondrial toxin 3-nitropropionic acid.
Topics: Adenosine Triphosphate; Aging; Corpus Striatum; In Vitro Techniques; Lactates; Lactic Acid; Mitochon | 1993 |
Regulation of malate dehydrogenases from neonatal, adolescent, and mature rat brain.
Topics: Aging; Animals; Animals, Newborn; Brain; Citrates; Citric Acid; Cytosol; Homeostasis; Ketoglutaric A | 1993 |
Interaction of exercise and age on substrates of carbohydrate metabolism.
Topics: Aging; Animals; Blood Glucose; Carbohydrate Metabolism; Glycogen; Lactates; Lactic Acid; Male; Physi | 1993 |
Cold acclimation and endurance training in guinea pigs: changes in daily and maximal metabolism.
Topics: Acclimatization; Aging; Animals; Basal Metabolism; Body Weight; Cold Temperature; Guinea Pigs; Lacta | 1995 |
Contribution of oligosaccharide and polysaccharide digestion, and excreta losses of lactic acid and short chain fatty acids, to dietary metabolisable energy values in broiler chickens and adult cockerels.
Topics: Aging; Amino Acids; Animal Feed; Animals; Chickens; Digestion; Energy Metabolism; Fatty Acids, Volat | 1995 |
Non-invasive neurochemical analysis of focal excitotoxic lesions in models of neurodegenerative illness using spectroscopic imaging.
Topics: Aging; Animals; Aspartic Acid; Electron Transport Complex II; Energy Metabolism; Huntington Disease; | 1996 |
Contents of D-lactate and its related metabolites as well as enzyme activities in the liver, muscle and blood plasma of aging rats.
Topics: Aging; Animals; Glutathione; Lactates; Lactic Acid; Lactoylglutathione Lyase; Liver; Male; Muscle, S | 1995 |
Hormonal regulation of hepatic gluconeogenesis: influence of age and training.
Topics: Aging; Animals; Gluconeogenesis; Glucose; Glycogen; Hormones; Lactic Acid; Liver; Male; Phosphoenolp | 1996 |
Age-related responses of right ventricle in swim-trained rats: changes in lactate and pyruvate contents and lactate dehydrogenase activity.
Topics: Aging; Anaerobiosis; Animals; Glycolysis; Hypertrophy, Right Ventricular; Isoenzymes; L-Lactate Dehy | 1996 |
Blood lactate and pyruvate concentrations, and their ratio during exercise in healthy children: developmental perspective.
Topics: Adolescent; Aging; Child; Child Development; Female; Humans; Lactic Acid; Male; Osmolar Concentratio | 1995 |
Evidence for a negative Pasteur effect in articular cartilage.
Topics: Adenosine Triphosphate; Aging; Animals; Antimetabolites; Carbonyl Cyanide m-Chlorophenyl Hydrazone; | 1997 |
Age-related ischemia in the brain following bilateral carotid artery occlusion--collateral blood flow and brain metabolism.
Topics: Adenosine Triphosphate; Aging; Animals; Animals, Suckling; Arterial Occlusive Diseases; Brain; Brain | 1997 |
Influence of endurance training on the age-related decline in hepatic glyconeogenesis.
Topics: Aging; Animals; Blood Glucose; Enzyme Inhibitors; Fructose; Glycogen; Lactic Acid; Liver; Male; Phos | 1994 |
Changes in production of ethanol, acids and H2 from glucose by the fecal flora of a 16- to 158-d-old breast-fed infant.
Topics: Acetates; Aging; Breast Feeding; Carboxylic Acids; Chromatography, High Pressure Liquid; Ethanol; Fe | 1998 |
Peak anaerobic power in elderly men.
Topics: Adult; Aged; Aged, 80 and over; Aging; Anaerobiosis; Ergometry; Female; Heart Rate; Humans; Lactic A | 1998 |
Lactate production from glucose and response to insulin in perifused adipocytes from mesenteric and epididymal regions of lean and obese rats.
Topics: Adipocytes; Aging; Animals; Body Weight; Cell Size; Epididymis; Fasting; Glucose; Insulin; Lactic Ac | 1998 |
Acute hormonal responses to heavy resistance exercise in younger and older men.
Topics: Adrenocorticotropic Hormone; Adult; Aging; Blood Glucose; Hormones; Human Growth Hormone; Humans; Hy | 1998 |
Butyrate and glucose metabolism in isolated colonocytes in the developing rat colon.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Aging; Animals; Animals, Newborn; Butyrates; Butyric Acid; Car | 1998 |
Plasma catecholamine and serum testosterone responses to four units of resistance exercise in young and adult male athletes.
Topics: Adolescent; Adult; Aging; Epinephrine; Exercise; Exercise Test; Heart Rate; Humans; Lactic Acid; Mal | 1998 |
Age-related differences in the effect of dichloroacetate on postischemic lactate and acid clearance measured in vivo using magnetic resonance spectroscopy and microdialysis.
Topics: Acids; Aging; Animals; Animals, Newborn; Body Temperature; Brain; Brain Ischemia; Dichloroacetic Aci | 1998 |
Age effect on in vitro fermentation pattern and methane production in the caeca of chickens.
Topics: Aging; Ammonia; Animals; Cecum; Chickens; Ethanol; Fatty Acids; Female; Fermentation; Hydrogen; Lact | 1998 |
Maintained exercise pressor response in heart failure.
Topics: Adult; Aged; Aged, 80 and over; Aging; Blood Pressure; Exercise; Female; Glycolysis; Heart Failure; | 1998 |
Affected enzyme activities in Alzheimer's disease are sensitive to antemortem hypoxia.
Topics: Adult; Aged; Aged, 80 and over; Aging; Alzheimer Disease; Brain; Cadaver; Female; Humans; Hypoxia; L | 1998 |
Correlation between hypermetabolism and neuronal damage during status epilepticus induced by lithium and pilocarpine in immature and adult rats.
Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Brain; Glucose; Lactic Acid; Lithium; Male; Nerv | 1999 |
Uptake and excretion of sodium taurocholate by the isolated perfused neonatal sheep liver.
Topics: Aging; Algorithms; Animals; Animals, Newborn; Bile; Blood Pressure; Lactic Acid; Liver; Liver Circul | 1999 |
Metabolite changes in neonatal rat brain during and after cerebral hypoxia-ischemia: a magnetic resonance spectroscopic imaging study.
Topics: Aging; Animals; Animals, Newborn; Aspartic Acid; Brain; Brain Ischemia; Cerebral Infarction; Female; | 1999 |
Myocardial lactate metabolism in fetal and newborn lambs.
Topics: Aging; Animals; Animals, Newborn; Arteries; Energy Metabolism; Fatty Acids; Fetal Blood; Fetus; Gluc | 1999 |
Low fertility in aging roosters is related to a high plasma concentration of insulin and low testicular contents of ACTH and lactate.
Topics: Adrenocorticotropic Hormone; Aging; Animals; Chickens; Fertility; Insulin; Lactic Acid; Male; Testis | 1999 |
Blunted growth hormone response to maximal exercise in middle-aged versus young subjects and no effect of endurance training.
Topics: Adult; Aging; Bicycling; Blood Glucose; Exercise; Human Growth Hormone; Humans; Insulin-Like Growth | 1999 |
Beta-adrenergically stimulated fat oxidation is diminished in middle-aged compared to young subjects.
Topics: Adrenergic beta-Agonists; Adult; Aging; Carbohydrate Metabolism; Dose-Response Relationship, Drug; E | 1999 |
Effect of ageing on the ventilatory response and lactate kinetics during incremental exercise in man.
Topics: Adult; Aging; Airway Resistance; Anaerobic Threshold; Exercise; Humans; Kinetics; Lactic Acid; Male; | 2000 |
Ischemic threshold and myocardial stunning in the aging heart.
Topics: Aging; Animals; Creatine Kinase; Heart; In Vitro Techniques; Lactic Acid; Male; Myocardial Stunning; | 1999 |
Ageing alters intrahypothalamic release patterns of vasopressin and oxytocin in rats.
Topics: Adrenocorticotropic Hormone; Aging; Animals; Catheterization; Corticosterone; Hypertonic Solutions; | 2000 |
Age-dependent metabolic effects of repeated hypoxemia in piglets.
Topics: Aging; Animals; Behavior, Animal; Carbon Dioxide; Catecholamines; Hemodynamics; Hypoxia; Lactic Acid | 2000 |
Maximal aerobic power, lactate threshold, and running performance in master athletes.
Topics: Adult; Aged; Aging; Female; Humans; Lactic Acid; Male; Middle Aged; Oxygen Consumption; Physical Fit | 2000 |
Assay of D-lactate in urine of infants and children with reference values taking into account data below detection limit.
Topics: Aging; Austria; Child, Preschool; Chile; Creatinine; Germany; Humans; Infant; Infant, Newborn; Lacti | 2000 |
Effects of fasting and exogenous glucose delivery on cardiac tolerance to low-flow ischemia in adult and senescent rats.
Topics: Aging; Animals; Coronary Circulation; Energy Metabolism; Fasting; Glucose; Glycogen; Glycolysis; In | 2000 |
The effect of age on the power/duration relationship and the intensity-domain limits in sedentary men.
Topics: Adult; Aged; Aging; Exercise Test; Humans; Lactic Acid; Male; Middle Aged; Oxygen Consumption; Physi | 2000 |
Age-dependent changes in glycosaminoglycan content in the skin of fasted rats. A possible mechanism.
Topics: Aging; Animals; Blood Glucose; Fasting; Glycosaminoglycans; Lactic Acid; Male; NAD; Pyruvic Acid; Ra | 2000 |
Differential increase in cerebral cortical glucose oxidative metabolism during rat postnatal development is greater in vivo than in vitro.
Topics: Aging; Animals; Blood Glucose; Carbon Isotopes; Cerebral Cortex; Citric Acid Cycle; Female; Glucose; | 2001 |
Decreased Pasteur effect in platelets of aged individuals.
Topics: Adenosine Triphosphate; Adult; Aged; Aged, 80 and over; Aging; Antimycin A; Blood Platelets; Cells, | 2001 |
Skeletal muscle fibre characteristics in young and old bulls and metabolic response after a bullfight.
Topics: Aging; Animals; Cattle; Glycogen; Hydrogen-Ion Concentration; Lactic Acid; Male; Muscle Fibers, Skel | 2001 |
MR spectroscopy detection of lactate and lipid signals in the brains of healthy elderly people.
Topics: Aged; Aged, 80 and over; Aging; Atrophy; Brain; Brain Chemistry; Female; Humans; Lactic Acid; Lipids | 2001 |
Maximal strength and power, endurance performance, and serum hormones in middle-aged and elderly men.
Topics: Adult; Aged; Aging; Bicycling; Biomechanical Phenomena; Energy Metabolism; Humans; Hydrocortisone; L | 2001 |
Relationship between physiological loss, performance decrement, and age in master athletes.
Topics: Absorptiometry, Photon; Adult; Aged; Aged, 80 and over; Aging; Blood Chemical Analysis; Body Composi | 2001 |
Very low dose of the Na(+)/Ca(2+) exchange inhibitor, KB-R7943, protects ischemic reperfused aged Fischer 344 rat hearts: considerable strain difference in the sensitivity to KB-R7943.
Topics: Adenosine Triphosphate; Aging; Animals; Calcium; Electrocardiography; Immunoblotting; Lactic Acid; M | 2001 |
Oligodendrocytes use lactate as a source of energy and as a precursor of lipids.
Topics: Aging; Animals; Astrocytes; Carbon Radioisotopes; Cell Culture Techniques; Central Nervous System; E | 2001 |
Ubiquinol and a coenzyme Q reducing system protect platelet mitochondrial function of transfusional buffy coats from oxidative stress.
Topics: Aging; Antioxidants; Blood Platelets; Cell Membrane; Cell Respiration; Chromatography, High Pressure | 2002 |
Temperature-induced changes in anaerobic capacity of interventricular septum in trained young and middle-aged rats.
Topics: Aging; Anaerobiosis; Animals; Cardiomegaly; Heart; Heart Septum; Heart Ventricles; Isoenzymes; L-Lac | 2002 |
Hepatic gluconeogenic capacity from various precursors in young versus old rats.
Topics: Aging; Alanine; Animals; Body Weight; Cell Separation; Cell Survival; Dihydroxyacetone; Fasting; Fru | 2002 |
The effect of rumen epithelial development on metabolic activities and ketogenesis by the tissue in vitro.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Aging; Animals; Butyrates; Butyric Acid; Epithelium; Glucose; | 1979 |
[The characteristics of lactate oxidation in the tissue mitochondria of rats of different ages].
Topics: Aging; Animals; Animals, Newborn; In Vitro Techniques; Lactates; Lactic Acid; Mitochondria, Heart; M | 1992 |
Age and training effects on the lactate kinetics of master athletes during maximal exercise.
Topics: Adult; Aged; Aging; Body Weight; Exercise; Humans; Kinetics; Lactates; Lactic Acid; Oxygen Consumpti | 1992 |
Effect of cold on serum substrate and glycogen concentration in young and old Fischer 344 rats.
Topics: Aging; Analysis of Variance; Animals; Blood Glucose; Body Temperature Regulation; Cold Temperature; | 1992 |
Predictive accuracy of criteria used to assess maximal oxygen consumption.
Topics: Aging; Ergometry; Female; Heart Rate; Humans; Lactates; Lactic Acid; Male; Oxygen Consumption; Proba | 1992 |
Hyperglycemia and the rate of lactic acid accumulation during cerebral ischemia in developing animals: in vivo proton MRS study.
Topics: Aging; Animals; Animals, Newborn; Blood Glucose; Brain; Dogs; Hyperglycemia; Ischemic Attack, Transi | 1992 |
Effects of age, photoperiod and follicle-stimulating hormone on lactate production by cultured Sertoli cells from prepubertal Siberian hamsters (Phodopus sungorus).
Topics: Aging; Animals; Cells, Cultured; Cricetinae; Follicle Stimulating Hormone; Lactates; Lactic Acid; Li | 1992 |
The time course in development of hypocalcemia and plasma lactate accumulation in mature and immature hyperthermic domestic fowl (Gallus domesticus).
Topics: Aging; Alkalosis, Respiratory; Animals; Chickens; Female; Fever; Hydrogen-Ion Concentration; Hypocal | 1991 |
Effects of the stress of sampling and of anaesthesia on the metabolic status of suckling rabbits.
Topics: Aging; Anesthesia; Animals; Animals, Suckling; Blood Glucose; Blood Specimen Collection; Glycogen; L | 1991 |
Glycolysis is predominant source of myocardial ATP production immediately after birth.
Topics: Adenosine Triphosphate; Aging; Animals; Animals, Newborn; Female; Glucose; Glycolysis; Heart; Kineti | 1991 |
Influence of aging, training and acute physical exercise on plasma glutathione and lipid peroxides in man.
Topics: Adult; Aging; Exercise; Exercise Test; Female; Glutathione; Humans; Lactates; Lactic Acid; Lipid Per | 1991 |
Metabolic maturation of the brain: a study of local cerebral glucose utilization in the developing cat.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Animals, Newborn; Autoradiography; Blood Glucose; Brain; Cats | 1991 |
Hormonal and metabolic changes during a strenuous tennis match. Effect of ageing.
Topics: Adolescent; Adult; Aging; Analysis of Variance; Arginine Vasopressin; Electrolytes; Epinephrine; Fem | 1991 |
Sepsis in the young rat: maternal milk protects during cecal ligation and puncture sepsis but not during endotoxemia.
Topics: Aging; Animals; Animals, Newborn; Blood Glucose; Cecum; Diet; Endotoxins; Lactates; Lactic Acid; Lig | 1991 |
Increased myocardial adenosine production and reduction of beta-adrenergic contractile response in aged hearts.
Topics: Adenosine; Aging; Animals; Calcium; Coronary Vessels; Guinea Pigs; Inosine; Lactates; Lactic Acid; M | 1990 |
Studies of myocardial protection in the immature heart. II. Evidence for importance of amino acid metabolism in tolerance to ischemia.
Topics: Adenosine Triphosphate; Aging; Amino Acids; Aminooxyacetic Acid; Animals; Aorta; Body Water; Constri | 1990 |
Blood lactate responses in older swimmers during active and passive recovery following maximal sprint swimming.
Topics: Adult; Aging; Exercise; Humans; Kinetics; Lactates; Lactic Acid; Male; Middle Aged; Swimming | 1990 |
[Acute changes in the body of laboratory rats during development after the parenteral administration of the herbicide Zeazin S-40. I. Determination of LD50 and other biochemical findings].
Topics: Aging; Animals; Blood Glucose; Female; Herbicides; Injections, Intraperitoneal; Lactates; Lactic Aci | 1990 |
Dynamic exercise in senescent beagles: oxygen consumption and hemodynamic responses.
Topics: Aging; Animals; Cardiac Output; Dogs; Female; Heart Rate; Hemodynamics; Lactates; Lactic Acid; Male; | 1989 |
The effect of lactic acid and the volatile fatty acids on the aggregation behavior of Periplaneta americana (L.).
Topics: Aging; Animals; Behavior, Animal; Chromatography, Gas; Cockroaches; Fatty Acids, Volatile; Lactates; | 1987 |
Correction to a 1980 article on CSF lactate and age.
Topics: Aging; Humans; Lactates; Lactic Acid; Probenecid | 1989 |
Gluconeogenesis from lactate in the small intestinal mucosa of suckling rats.
Topics: Aging; Animals; Animals, Suckling; Bucladesine; Epoxy Compounds; Fatty Acids; Gluconeogenesis; Glyco | 1986 |
Metabolic responses to exercise in young and older athletes and sedentary men.
Topics: Adult; Aged; Aging; Blood Glucose; Catecholamines; Fatty Acids, Nonesterified; Glycerol; Growth Horm | 1988 |
Increased excretion of propan-1,3-diol and 3-hydroxypropionic acid apparently caused by abnormal bacterial metabolism in the gut.
Topics: Aging; Bacterial Infections; Digestive System; Female; Gas Chromatography-Mass Spectrometry; Humans; | 1987 |
Hemodynamic and biochemical responses during exercise at the intensity equivalent to lactate threshold for middle-aged and elderly women.
Topics: Adult; Aging; Anaerobiosis; Energy Metabolism; Exercise; Female; Hemodynamics; Humans; Lactates; Lac | 1987 |
Increased basal gluconeogenesis in the aged rat.
Topics: Aging; Animals; Blood Glucose; Glucagon; Gluconeogenesis; Glycogen; Insulin; Kinetics; Lactates; Lac | 1986 |
The role of the sarcoplasmic reticulum in the response of ferret and rat heart muscle to acidosis.
Topics: Acidosis; Aequorin; Aging; Ammonium Chloride; Animals; Caffeine; Calcium; Ferrets; Hydrogen-Ion Conc | 1987 |
Why are newborn hearts vulnerable to global ischemia? The lactate hypothesis.
Topics: Aging; Animals; Animals, Newborn; Body Weight; Coronary Circulation; Coronary Disease; Heart; Heart | 1987 |
Relative vulnerability of neonatal and adult hearts to ischemic injury.
Topics: Adenosine Triphosphate; Aging; Animals; Animals, Newborn; Coronary Circulation; Glucose-6-Phosphate; | 1987 |
Ventilatory threshold: measurement and variation with age.
Topics: Adult; Aged; Aged, 80 and over; Aging; Exercise Test; Female; Humans; Lactates; Lactic Acid; Male; M | 1987 |
Training responses of two age groups during treadmill walking.
Topics: Adolescent; Adult; Aging; Blood Pressure; Exercise Test; Heart Rate; Hematocrit; Humans; Lactates; L | 1986 |
Age-associated changes of exercise-induced plasma catecholamine responses.
Topics: Adult; Aged; Aging; Catecholamines; Epinephrine; Exercise Test; Heart Rate; Humans; Lactates; Lactic | 1986 |
The effect of age on energy metabolism and resistance to ischaemic conduction failure in rat peripheral nerve.
Topics: Action Potentials; Adenosine Triphosphate; Aging; Animals; Energy Metabolism; Ischemia; Lactates; La | 1986 |
Influence of hormones and undernutrition on brain development in newborn rats.
Topics: Aging; Animals; Animals, Newborn; Blood Glucose; Body Weight; Brain; Corticosterone; Female; Food De | 1985 |
Some characteristics of circulating erythrocytes in polycythaemia vera: common features with normal young and foetal red blood cells.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Aging; Diphosphoglyceric Acids; Erythrocyte Indices; | 1986 |
The effect of age on glucose and energy metabolism in brain cortex of rats.
Topics: Adenosine Triphosphate; Aging; Animals; Cerebral Cortex; Citrates; Citric Acid; Energy Metabolism; G | 1985 |
Urea synthesis in hepatocytes isolated from young and old rats.
Topics: Aging; Ammonium Chloride; Animals; Epinephrine; Glucagon; Gluconeogenesis; In Vitro Techniques; Lact | 1985 |