lactic acid has been researched along with Age-Related Memory Disorders in 16 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "d-Lactic acidosis is associated with memory impairment in humans." | 3.76 | Increased plasma d-lactic acid associated with impaired memory in rats. ( Clayton, EH; Hanstock, TL; Mallet, PE, 2010) |
| "Curcumin is a natural product with several anti-Alzheimer's disease (AD) neuroprotective properties." | 1.51 | Curcumin Ameliorates Memory Deficits by Enhancing Lactate Content and MCT2 Expression in APP/PS1 Transgenic Mouse Model of Alzheimer's Disease. ( Gan, SW; Huang, J; Huang, SQ; Jiang, XL; Li, Y; Lu, WT; Qiu, GP; Sun, SQ; Xu, J; Xu, SY; Zhuo, F, 2019) |
| "The pre-training administration caused memory loss from the earliest time tested whereas memory was maintained for another 20 min when D-lactate was injected 10 min post-training." | 1.35 | Inhibition of astrocytic energy metabolism by D-lactate exposure impairs memory. ( Gibbs, ME; Hertz, L, 2008) |
| "Huperzine A is an anticholinesterase and cognitive enhancer, which is able to alleviate the symptoms of memory dysfunction in the mouse." | 1.34 | Prolonged effects of poly(lactic-co-glycolic acid) microsphere-containing huperzine A on mouse memory dysfunction induced by scopolamine. ( Fu, F; Liu, J; Liu, K; Ma, H; Wang, C; Zhang, T, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 9 (56.25) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Frame, AK | 1 |
| Robinson, JW | 1 |
| Mahmoudzadeh, NH | 1 |
| Tennessen, JM | 1 |
| Simon, AF | 1 |
| Cumming, RC | 1 |
| Akter, M | 1 |
| Hasan, M | 1 |
| Ramkrishnan, AS | 1 |
| Iqbal, Z | 1 |
| Zheng, X | 1 |
| Fu, Z | 1 |
| Lei, Z | 1 |
| Karim, A | 1 |
| Li, Y | 4 |
| Kee, CK | 1 |
| Ngam, PI | 1 |
| Tan, AP | 1 |
| Liguori, C | 1 |
| Mercuri, NB | 1 |
| Izzi, F | 1 |
| Romigi, A | 1 |
| Cordella, A | 1 |
| Sancesario, G | 1 |
| Placidi, F | 1 |
| Jin, C | 1 |
| Gao, L | 1 |
| Wu, S | 1 |
| Lu, X | 1 |
| Yang, J | 1 |
| Cai, Y | 1 |
| Lu, WT | 1 |
| Sun, SQ | 1 |
| Xu, SY | 1 |
| Gan, SW | 1 |
| Xu, J | 1 |
| Qiu, GP | 1 |
| Zhuo, F | 1 |
| Huang, SQ | 1 |
| Jiang, XL | 1 |
| Huang, J | 1 |
| Descalzi, G | 1 |
| Gao, V | 1 |
| Steinman, MQ | 1 |
| Suzuki, A | 1 |
| Alberini, CM | 1 |
| Martikainen, MH | 1 |
| Ellfolk, U | 1 |
| Majamaa, K | 1 |
| Gibbs, ME | 2 |
| Gibbs, Z | 1 |
| Hertz, L | 2 |
| Hanstock, TL | 1 |
| Mallet, PE | 1 |
| Clayton, EH | 1 |
| Aguiar, AS | 1 |
| Boemer, G | 1 |
| Rial, D | 1 |
| Cordova, FM | 1 |
| Mancini, G | 1 |
| Walz, R | 1 |
| de Bem, AF | 1 |
| Latini, A | 1 |
| Leal, RB | 1 |
| Pinho, RA | 1 |
| Prediger, RD | 1 |
| Hazekawa, M | 1 |
| Sakai, Y | 1 |
| Yoshida, M | 1 |
| Haraguchi, T | 1 |
| Uchida, T | 1 |
| Wang, C | 1 |
| Zhang, T | 1 |
| Ma, H | 1 |
| Liu, J | 1 |
| Fu, F | 1 |
| Liu, K | 1 |
| Chu, D | 1 |
| Tian, J | 1 |
| Liu, W | 1 |
| Li, Z | 1 |
| Anezaki, T | 1 |
| Yanagisawa, K | 1 |
| Ibayashi, K | 1 |
| Miyatake, T | 1 |
16 other studies available for lactic acid and Age-Related Memory Disorders
| Article | Year |
|---|---|
Aging and memory are altered by genetically manipulating lactate dehydrogenase in the neurons or glia of flies.
Topics: Animals; Astrocytes; Drosophila melanogaster; L-Lactate Dehydrogenase; Lactic Acid; Lipids; Memory D | 2023 |
Astrocyte and L-lactate in the anterior cingulate cortex modulate schema memory and neuronal mitochondrial biogenesis.
Topics: Animals; Astrocytes; Gyrus Cinguli; Lactic Acid; Memory; Memory Disorders; Organelle Biogenesis; Rat | 2023 |
An Unusual Cause of Stroke-Like Symptoms in an Elderly Patient.
Topics: Aphasia; Cerebral Angiography; Diagnosis, Differential; Electroencephalography; Humans; Lactic Acid; | 2019 |
Obstructive Sleep Apnea is Associated With Early but Possibly Modifiable Alzheimer's Disease Biomarkers Changes.
Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Cognition; Cognitive Dysfunction; Contin | 2017 |
Lanthanum damages learning and memory and suppresses astrocyte-neuron lactate shuttle in rat hippocampus.
Topics: Animals; Astrocytes; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gene Expressi | 2017 |
Curcumin Ameliorates Memory Deficits by Enhancing Lactate Content and MCT2 Expression in APP/PS1 Transgenic Mouse Model of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Anti-Inflammatory Agents, Non-Steroidal; | 2019 |
Lactate from astrocytes fuels learning-induced mRNA translation in excitatory and inhibitory neurons.
Topics: Animals; Astrocytes; Avoidance Learning; Brain; Citric Acid Cycle; Gangliosides; Glycogenolysis; Hip | 2019 |
Impaired information-processing speed and working memory in leukoencephalopathy with brainstem and spinal cord involvement and elevated lactate (LBSL) and DARS2 mutations: a report of three adult patients.
Topics: Adolescent; Age of Onset; Aspartate-tRNA Ligase; Brain Stem; Child; Cognition; Disease Progression; | 2013 |
Rescue of Abeta(1-42)-induced memory impairment in day-old chick by facilitation of astrocytic oxidative metabolism: implications for Alzheimer's disease.
Topics: 3-Hydroxybutyric Acid; Acetates; Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Newborn | 2009 |
Increased plasma d-lactic acid associated with impaired memory in rats.
Topics: Acidosis, Lactic; Analysis of Variance; Animals; Diet; Fermentation; Lactic Acid; Male; Memory Disor | 2010 |
High-intensity physical exercise disrupts implicit memory in mice: involvement of the striatal glutathione antioxidant system and intracellular signaling.
Topics: Adaptation, Physiological; Analysis of Variance; Animals; Corpus Striatum; Disease Models, Animal; E | 2010 |
The effect of treatment with a sustained-release prostacyclin analogue (ONO-1301-loaded PLGA microsphere) on short-term memory impairment in rats with transient global cerebral ischemia.
Topics: Animals; Brain Ischemia; CA1 Region, Hippocampal; Delayed-Action Preparations; Disease Models, Anima | 2012 |
Prolonged effects of poly(lactic-co-glycolic acid) microsphere-containing huperzine A on mouse memory dysfunction induced by scopolamine.
Topics: Acetylcholinesterase; Alkaloids; Animals; Avoidance Learning; Cerebral Cortex; Delayed-Action Prepar | 2007 |
Poly(lactic-co-glycolic acid) microspheres for the controlled release of huperzine A: in vitro and in vivo studies and the application in the treatment of the impaired memory of mice.
Topics: Alkaloids; Animals; Cholinesterase Inhibitors; Lactic Acid; Memory Disorders; Mice; Microspheres; Po | 2007 |
Inhibition of astrocytic energy metabolism by D-lactate exposure impairs memory.
Topics: Acetic Acid; Animals; Astrocytes; Brain; Chickens; Citric Acid Cycle; Energy Metabolism; Glutamic Ac | 2008 |
A patient with severe iron-deficiency anemia and memory disturbance.
Topics: Anemia, Hypochromic; Diet; Female; Humans; Intelligence; Iron; Lactates; Lactic Acid; Memory Disorde | 1992 |