lactic acid has been researched along with Adult Spinal Muscular Atrophy in 3 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Proximal Spinal Muscular Atrophy (SMA) is a debilitating neuromuscular disease and a leading inherited genetic cause of infant death." | 1.38 | Prediction of death in the SMNΔ7 mouse model of spinal muscular atrophy: insight into disease stage and progression. ( Beltran, JA; Charney, R; Chomicova, O; Cirillo, K; El-Khodor, BF; Marino, T; Mushlin, R; Ramboz, S; Winberg, ML, 2012) |
| "All patients with spinal muscular atrophy and congenital myopathy and one patient with Duchenne dystrophy, but none of six healthy subjects, developed hypoglycemia." | 1.32 | Patients with severe muscle wasting are prone to develop hypoglycemia during fasting. ( Hebert, A; Laub, M; Vissing, J; Zacho, M; Ørngreen, MC, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| El-Khodor, BF | 1 |
| Cirillo, K | 1 |
| Beltran, JA | 1 |
| Mushlin, R | 1 |
| Winberg, ML | 1 |
| Charney, R | 1 |
| Chomicova, O | 1 |
| Marino, T | 1 |
| Ramboz, S | 1 |
| Ørngreen, MC | 1 |
| Zacho, M | 1 |
| Hebert, A | 1 |
| Laub, M | 1 |
| Vissing, J | 1 |
| Karitzky, J | 1 |
| Block, W | 1 |
| Mellies, JK | 1 |
| Träber, F | 1 |
| Sperfeld, A | 1 |
| Schild, HH | 1 |
| Haller, P | 1 |
| Ludolph, AC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacokinetics and Safety of Treatment With Paracetamol in Children and Adults With Spinal Muscular Atrophy and Cerebral Palsy[NCT03648658] | Phase 4 | 48 participants (Anticipated) | Interventional | 2019-02-18 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for lactic acid and Adult Spinal Muscular Atrophy
| Article | Year |
|---|---|
Prediction of death in the SMNΔ7 mouse model of spinal muscular atrophy: insight into disease stage and progression.
Topics: Age Factors; Animals; Animals, Newborn; Body Weight; Brain; Computer Simulation; Dichloroacetic Acid | 2012 |
Patients with severe muscle wasting are prone to develop hypoglycemia during fasting.
Topics: Adult; Alanine; Blood Glucose; Body Weight; Fasting; Fatty Acids, Nonesterified; Female; Glycerol; H | 2003 |
Proton magnetic resonance spectroscopy in Kennedy syndrome.
Topics: Acetylation; Adult; Brain Stem; Choline; Family Health; Gliosis; Humans; Lactic Acid; Magnetic Reson | 1999 |