Page last updated: 2024-10-17

lactic acid and Adenocarcinoma

lactic acid has been researched along with Adenocarcinoma in 62 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Adenocarcinoma: A malignant epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
"Resistance to gemcitabine remains a key challenge in the treatment of pancreatic ductal adenocarcinoma (PDAC), necessitating the constant search for effective strategies for a priori prediction of clinical outcome."7.88Metabolomic prediction of treatment outcome in pancreatic ductal adenocarcinoma patients receiving gemcitabine. ( Alkaff, SMF; Chan, CY; Chan, ECY; Goh, S; Kam, JH; Leow, WQ; Lim, TKH; Phua, LC; Tai, DWM, 2018)
" In this work CUR-NPs (curcumin-loaded lipid-polymer-lecithin hybrid nanoparticles) were synthesized and functionalized with ribonucleic acid (RNA) Aptamers (Apts) against epithelial cell adhesion molecule (EpCAM) for targeted delivery to colorectal adenocarcinoma cells."7.80Epithelial cell adhesion molecule aptamer functionalized PLGA-lecithin-curcumin-PEG nanoparticles for targeted drug delivery to human colorectal adenocarcinoma cells. ( Duan, W; Li, L; Li, Q; Lin, J; Liu, K; Shigdar, S; Xiang, D; Yang, W, 2014)
" Mutations in the tyrosine kinase epidermal growth factor receptor (EGFR) induce oncogenic addiction in lung adenocarcinoma (LAD)."7.80Epidermal growth factor receptor (EGFR) signaling regulates global metabolic pathways in EGFR-mutated lung adenocarcinoma. ( Esumi, H; Makinoshima, H; Matsumoto, S; Owada, S; Takita, M; Tsuchihara, K; Yagishita, A, 2014)
" However, due to its minimal water solubility, it is necessary to prepare an optimal nano-sized vehicle to overcome the low bioavailability issue."5.72Design and Development of a New Type of Hybrid PLGA/Lipid Nanoparticle as an Ursolic Acid Delivery System against Pancreatic Ductal Adenocarcinoma Cells. ( Gubernator, J; Jaromin, A; Markowski, A; Migdał, P; Olczak, E; Pawlik, K; Zaremba-Czogalla, M; Zygmunt, A, 2022)
"Metabolic profiles of human colon cancer cells have been extensively studied, but comparison with non-tumour counterparts has been neglected."5.40Validation of NCM460 cell model as control in antitumor strategies targeting colon adenocarcinoma metabolic reprogramming: trichostatin A as a case study. ( Alcarraz-Vizán, G; Cascante, M; Moyer, MP; Sánchez-Tena, S, 2014)
"Resistance to gemcitabine remains a key challenge in the treatment of pancreatic ductal adenocarcinoma (PDAC), necessitating the constant search for effective strategies for a priori prediction of clinical outcome."3.88Metabolomic prediction of treatment outcome in pancreatic ductal adenocarcinoma patients receiving gemcitabine. ( Alkaff, SMF; Chan, CY; Chan, ECY; Goh, S; Kam, JH; Leow, WQ; Lim, TKH; Phua, LC; Tai, DWM, 2018)
" While age was found to be a significant factor driving microbiome composition, bacterial signatures and functions such as enrichment with Gram-negative oral-associated bacteria and microbial lactic acid production were associated with the early stages of the esophageal adenocarcinoma cascade."3.88Signatures within the esophageal microbiome are associated with host genetics, age, and disease. ( Castaño-Rodríguez, N; Deshpande, NP; Kaakoush, NO; Riordan, SM; Wilkins, MR, 2018)
" In this work CUR-NPs (curcumin-loaded lipid-polymer-lecithin hybrid nanoparticles) were synthesized and functionalized with ribonucleic acid (RNA) Aptamers (Apts) against epithelial cell adhesion molecule (EpCAM) for targeted delivery to colorectal adenocarcinoma cells."3.80Epithelial cell adhesion molecule aptamer functionalized PLGA-lecithin-curcumin-PEG nanoparticles for targeted drug delivery to human colorectal adenocarcinoma cells. ( Duan, W; Li, L; Li, Q; Lin, J; Liu, K; Shigdar, S; Xiang, D; Yang, W, 2014)
" Mutations in the tyrosine kinase epidermal growth factor receptor (EGFR) induce oncogenic addiction in lung adenocarcinoma (LAD)."3.80Epidermal growth factor receptor (EGFR) signaling regulates global metabolic pathways in EGFR-mutated lung adenocarcinoma. ( Esumi, H; Makinoshima, H; Matsumoto, S; Owada, S; Takita, M; Tsuchihara, K; Yagishita, A, 2014)
" The present study demonstrates that chitosan (CS)-modified PLGA NSs (CS-PLGA NSs) are preferentially taken up by human lung adenocarcinoma cells (A549)."3.75Improved cellular uptake of chitosan-modified PLGA nanospheres by A549 cells. ( Hirashima, N; Kawashima, Y; Sakai, T; Tahara, K; Takeuchi, H; Yamamoto, H, 2009)
" However, due to its minimal water solubility, it is necessary to prepare an optimal nano-sized vehicle to overcome the low bioavailability issue."1.72Design and Development of a New Type of Hybrid PLGA/Lipid Nanoparticle as an Ursolic Acid Delivery System against Pancreatic Ductal Adenocarcinoma Cells. ( Gubernator, J; Jaromin, A; Markowski, A; Migdał, P; Olczak, E; Pawlik, K; Zaremba-Czogalla, M; Zygmunt, A, 2022)
"Previous studies have shown that cervical cancer cells display markers of aerobic glycolysis, indicating that these tumors are likely to secrete lactate."1.51Lactate secreted by cervical cancer cells modulates macrophage phenotype. ( Alvarez, KLF; Baracat, EC; Boccardo, E; Carvalho, JP; Lepique, AP; Lorenzi, NP; Margarido, PFR; Rossetti, RAM; Stone, SC; Tacla, M; Yokochi, K, 2019)
"In the treatment of lung adenocarcinoma, targeting PFKFB3 would be a promising therapeutic strategy."1.48Expression of PFKFB3 and Ki67 in lung adenocarcinomas and targeting PFKFB3 as a therapeutic strategy. ( Ke, H; Li, X; Liu, J; Liu, Y; Qian, L; Tian, W; Yao, C; Zhang, J, 2018)
"The two main histological variants, squamous cell carcinomas (SCC) and adenocarcinomas (AC), resemble the cell morphology of exocervix and endocervix, respectively."1.43STAT3:FOXM1 and MCT1 drive uterine cervix carcinoma fitness to a lactate-rich microenvironment. ( Dias, S; Domingues, G; Felix, A; Ferreira, J; Goncalves, LG; Lam, EW; Maximo, V; Serpa, J; Silva, F; Silva, LS, 2016)
"Metabolic profiles of human colon cancer cells have been extensively studied, but comparison with non-tumour counterparts has been neglected."1.40Validation of NCM460 cell model as control in antitumor strategies targeting colon adenocarcinoma metabolic reprogramming: trichostatin A as a case study. ( Alcarraz-Vizán, G; Cascante, M; Moyer, MP; Sánchez-Tena, S, 2014)
") Thus, overall results suggest that nano-encapsulation of PD (NPD) increases drug bioavailability and thereby has a better chemo-preventive action against lung cancer in vivo and on A549 cells in vitro than that of PD."1.38Poly (lactide-co-glycolide) encapsulated extract of Phytolacca decandra demonstrates better intervention against induced lung adenocarcinoma in mice and on A549 cells. ( Bhadra, K; Das, J; Das, S; Khuda-Bukhsh, AR; Samadder, A, 2012)
"The purpose of this work was to assess synergistic inhibitory responses of a novel chemopreventive combination regimen of drugs namely, aspirin in combination with calcium and folic acid on two human colon cancer cell lines, HT-29 and SW-480."1.36Nanoparticulate delivery of novel drug combination regimens for the chemoprevention of colon cancer. ( Chaudhary, A; Kanthamneni, N; Prabhu, S; Wang, J, 2010)

Research

Studies (62)

TimeframeStudies, this research(%)All Research%
pre-19904 (6.45)18.7374
1990's4 (6.45)18.2507
2000's12 (19.35)29.6817
2010's33 (53.23)24.3611
2020's9 (14.52)2.80

Authors

AuthorsStudies
Govindarasu, M1
Abirami, P1
Alharthi, SS1
Thiruvengadam, M1
Rajakumar, G1
Vaiyapuri, M1
Mai, S1
Liang, L1
Mai, G1
Liu, X1
Diao, D1
Cai, R1
Liu, L1
Chen, Y3
Hu, L1
Lin, H1
Yu, H1
You, J1
Markowski, A1
Jaromin, A1
Migdał, P1
Olczak, E1
Zygmunt, A1
Zaremba-Czogalla, M1
Pawlik, K1
Gubernator, J1
Chen, Z1
Song, Y1
Li, P2
Gao, W2
Cheng, S1
Li, Z1
Bai, X1
Feng, J1
Su, R1
Song, L1
Yang, H1
Zhan, X1
Xia, X1
Lü, X1
Shi, C1
Wang, M1
He, T1
Meng, D1
Lv, W1
Ye, J1
Cheng, L1
Hu, J1
Donisi, G1
Barbagallo, M1
Capretti, G1
Nappo, G1
Takis, PG1
Zerbi, A1
Marchesi, F1
Cortese, N1
Markovic, S1
Roussel, T1
Agemy, L1
Sasson, K1
Preise, D1
Scherz, A1
Frydman, L1
Phua, LC1
Goh, S1
Tai, DWM1
Leow, WQ1
Alkaff, SMF1
Chan, CY1
Kam, JH1
Lim, TKH1
Chan, ECY1
Li, X1
Liu, J1
Qian, L1
Ke, H1
Yao, C1
Tian, W1
Liu, Y1
Zhang, J1
Sahin, A1
Spiroux, F1
Guedon, I1
Arslan, FB1
Sarcan, ET1
Ozkan, T1
Colak, N1
Yuksel, S1
Ozdemir, S1
Ozdemir, B1
Akbas, S1
Ultav, G1
Aktas, Y1
Capan, Y1
Milshteyn, E1
von Morze, C1
Gordon, JW1
Zhu, Z1
Larson, PEZ1
Vigneron, DB3
Jiang, W1
Wang, H1
Cui, Y1
Lei, Y1
Wang, Y2
Xu, D1
Jiang, N1
Sun, Y1
Zhang, Y1
Cao, J1
Ke, Z1
Deshpande, NP1
Riordan, SM1
Castaño-Rodríguez, N1
Wilkins, MR1
Kaakoush, NO1
Stone, SC1
Rossetti, RAM1
Alvarez, KLF1
Carvalho, JP1
Margarido, PFR1
Baracat, EC1
Tacla, M1
Boccardo, E1
Yokochi, K1
Lorenzi, NP1
Lepique, AP1
Xing, Y1
Reed, GD1
Pauly, JM2
Kerr, AB2
Larson, PE2
He, X1
Mishchuk, DO1
Shah, J1
Weimer, BC1
Slupsky, CM1
Alcarraz-Vizán, G1
Sánchez-Tena, S1
Moyer, MP1
Cascante, M1
Chen, L1
Zeng, F1
Kong, LX1
Li, L1
Xiang, D1
Shigdar, S1
Yang, W1
Li, Q1
Lin, J1
Liu, K1
Duan, W1
An, YJ1
Cho, HR1
Kim, TM1
Keam, B1
Kim, JW1
Wen, H1
Park, CK1
Lee, SH1
Im, SA1
Kim, JE1
Choi, SH1
Park, S1
Makinoshima, H2
Takita, M2
Matsumoto, S2
Yagishita, A1
Owada, S1
Esumi, H2
Tsuchihara, K2
Jiang, L1
Wang, R1
Lu, M1
Zhang, Q1
Zhou, Y1
Wang, Z1
Lu, G1
Liang, P1
Ran, H1
Chen, H1
Zheng, Y1
Tsujimoto, H1
Morimoto, Y1
Takahata, R1
Nomura, S1
Yoshida, K2
Hiraki, S1
Horiguchi, H1
Miyazaki, H1
Ono, S1
Saito, D1
Hara, I1
Ozeki, E1
Yamamoto, J1
Hase, K1
Saruwatari, K1
Umemura, S1
Obata, Y1
Ishii, G1
Sugiyama, E1
Ochiai, A1
Abe, R1
Goto, K1
Essa, S1
Daoud, J1
Lafleur, M1
Martel, S1
Tabrizian, M1
Vlachostergios, PJ1
Oikonomou, KG1
Gibilaro, E1
Apergis, G1
Silva, LS1
Goncalves, LG1
Silva, F1
Domingues, G1
Maximo, V1
Ferreira, J1
Lam, EW1
Dias, S1
Felix, A1
Serpa, J1
Bernacchioni, C1
Ghini, V1
Cencetti, F1
Japtok, L1
Donati, C1
Bruni, P1
Turano, P1
Albers, MJ1
Bok, R1
Chen, AP1
Cunningham, CH1
Zierhut, ML1
Zhang, VY1
Kohler, SJ1
Tropp, J1
Hurd, RE1
Yen, YF1
Nelson, SJ1
Kurhanewicz, J1
Patil, Y1
Sadhukha, T1
Ma, L1
Panyam, J1
Tahara, K2
Sakai, T1
Yamamoto, H2
Takeuchi, H1
Hirashima, N1
Kawashima, Y2
Wartenberg, M1
Richter, M1
Datchev, A1
Günther, S1
Milosevic, N1
Bekhite, MM1
Figulla, HR1
Aran, JM1
Pétriz, J1
Sauer, H1
Kanthamneni, N1
Chaudhary, A1
Wang, J1
Prabhu, S1
Mishra, D1
Kang, HC1
Bae, YH1
Şengel-Türk, CT1
Hasçiçek, C1
Dogan, AL1
Esendagli, G1
Guc, D1
Gönül, N1
Zhang, L1
Webster, TJ1
Dauchy, RT1
Dauchy, EM1
Mao, L1
Belancio, VP1
Hill, SM1
Blask, DE1
Mueller, M1
Reichardt, W1
Koerner, J1
Groettrup, M1
Das, J1
Das, S1
Samadder, A1
Bhadra, K1
Khuda-Bukhsh, AR1
Hur, H1
Xuan, Y1
Kim, YB1
Lee, G1
Shim, W1
Yun, J1
Ham, IH1
Han, SU1
Swisher, CL1
Jiménez, B1
Mirnezami, R1
Kinross, J1
Cloarec, O1
Keun, HC1
Holmes, E1
Goldin, RD1
Ziprin, P1
Darzi, A1
Nicholson, JK1
Zhang, GZ1
Huang, GJ1
Li, WL1
Wu, GM1
Qian, GS1
Walenta, S2
Chau, TV1
Schroeder, T1
Lehr, HA1
Kunz-Schughart, LA1
Fuerst, A1
Mueller-Klieser, W1
RAMKISSOON, RA1
CHAMBERLAIN, NO1
BAKER, EL1
JENNINGS, ER1
Alrefai, WA1
Tyagi, S1
Gill, R1
Saksena, S1
Hadjiagapiou, C1
Mansour, F1
Ramaswamy, K1
Dudeja, PK1
Guo, J1
Higashi, K1
Yokota, H1
Nagao, Y1
Ueda, Y1
Kodama, Y1
Oguchi, M1
Taki, S1
Tonami, H1
Yamamoto, I1
VANNOTTI, A1
NEUKOMM, S1
Koukourakis, MI1
Giatromanolaki, A1
Harris, AL1
Sivridis, E1
Son, HJ1
Kim, JS1
Tamulevicius, P1
Streffer, C1
Waki, A1
Fujibayashi, Y1
Sadato, N1
Tsuchida, T1
Ishii, Y1
Yokoyama, A1
Yonekura, Y1
Wang, F1
Larsson, J1
Adrian, TE1
Gasslander, T1
Permert, J1
Parnaud, G1
Corpet, DE1
Gamet-Payrastre, L1
Sabel, MS1
Hill, H1
Jong, YS1
Mathiowitz, E1
Bankert, RB1
Egilmez, NK1
Morello, E1
Dernell, WS1
Kuntz, CA1
LaRue, SM1
Lafferty, M1
Nelson, A1
Brekke, JH1
Mallinckrodt, CH1
Withrow, SJ1
Manning, MC1
Wiedemann, G1
Müller-Klieser, W1
Schleinkofer, L1
Wood, WG1
Tisdale, MJ1
Brennan, RA1
Takahashi, M1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Hyperpolarized 13-C Pyruvate MRI Surveillance of Multiple Cancers[NCT05697406]Phase 1/Phase 225 participants (Anticipated)Interventional2024-02-01Not yet recruiting
A Phase 1 Ascending-dose Study to Assess the Safety and Tolerability and Imaging Potential of Hyperpolarized Pyruvate (13C) Injection in Subjects With Prostate Cancer[NCT01229618]Phase 131 participants (Actual)Interventional2010-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for lactic acid and Adenocarcinoma

ArticleYear
Elevated lactic acid is a negative prognostic factor in metastatic lung cancer.
    Cancer biomarkers : section A of Disease markers, 2015, Volume: 15, Issue:6

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Large Cell; Carcinoma, Non-Sm

2015

Other Studies

61 other studies available for lactic acid and Adenocarcinoma

ArticleYear
Synthesis, physicochemical characterization, and in vitro evaluation of biodegradable PLGA nanoparticles entrapped to folic acid for targeted delivery of kaempferitrin.
    Biotechnology and applied biochemistry, 2022, Volume: 69, Issue:6

    Topics: Adenocarcinoma; Colonic Neoplasms; Drug Carriers; Folic Acid; Humans; Lactic Acid; Nanoparticles; Pa

2022
Development and Validation of Lactate Metabolism-Related lncRNA Signature as a Prognostic Model for Lung Adenocarcinoma.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Adenocarcinoma; Biomarkers, Tumor; CD8-Positive T-Lymphocytes; Humans; Lactic Acid; Lung; Prognosis;

2022
Serum metabolomic profiling for patients with adenocarcinoma of the esophagogastric junction.
    Metabolomics : Official journal of the Metabolomic Society, 2022, 04-19, Volume: 18, Issue:5

    Topics: Adenocarcinoma; Esophagogastric Junction; Glutamic Acid; Humans; Lactic Acid; Metabolomics; Stomach

2022
Design and Development of a New Type of Hybrid PLGA/Lipid Nanoparticle as an Ursolic Acid Delivery System against Pancreatic Ductal Adenocarcinoma Cells.
    International journal of molecular sciences, 2022, May-16, Volume: 23, Issue:10

    Topics: Adenocarcinoma; Humans; Lactic Acid; Liposomes; Nanoparticles; Pancreatic Neoplasms; Particle Size;

2022
GRIN2D knockdown suppresses the progression of lung adenocarcinoma by regulating the E2F signalling pathway.
    Cellular signalling, 2023, Volume: 107

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Cell Proliferation; Gene Expression Regulation, Neoplastic;

2023
The biochemical characteristics of viable but nonculturable state Yersinia enterocolitica induced by lactic acid stress and its presence in food systems.
    Food research international (Ottawa, Ont.), 2023, Volume: 170

    Topics: Adenocarcinoma; Caco-2 Cells; Caffeine; Humans; Lactic Acid; Yersinia enterocolitica

2023
BZW2 Modulates Lung Adenocarcinoma Progression through Glycolysis-Mediated IDH3G Lactylation Modification.
    Journal of proteome research, 2023, 12-01, Volume: 22, Issue:12

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Cell Line, Tumor; Cell Proliferation; Gene Expressi

2023
Isolation of Proximal Fluids to Investigate the Tumor Microenvironment of Pancreatic Adenocarcinoma.
    Journal of visualized experiments : JoVE, 2020, 11-05, Issue:165

    Topics: Adenocarcinoma; Animals; Biomarkers, Tumor; Cell Line, Tumor; Extracellular Fluid; Glucose; Humans;

2020
Deuterium MRSI characterizations of glucose metabolism in orthotopic pancreatic cancer mouse models.
    NMR in biomedicine, 2021, Volume: 34, Issue:9

    Topics: Adenocarcinoma; Animals; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Deuterium; Disease Models,

2021
Metabolomic prediction of treatment outcome in pancreatic ductal adenocarcinoma patients receiving gemcitabine.
    Cancer chemotherapy and pharmacology, 2018, Volume: 81, Issue:2

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Biomarkers; Carcinoma, Pancreatic Ductal; Deo

2018
Expression of PFKFB3 and Ki67 in lung adenocarcinomas and targeting PFKFB3 as a therapeutic strategy.
    Molecular and cellular biochemistry, 2018, Volume: 445, Issue:1-2

    Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Adult; Aged; Aged, 80 and over; Apoptosis; Bioma

2018
Using PVA and TPGS as combined emulsifier in nanoprecipitation method improves characteristics and anticancer activity of ibuprofen loaded PLGA nanoparticles.
    Die Pharmazie, 2017, Sep-01, Volume: 72, Issue:9

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Breast Neoplasms; Caco-2 Cells; Chemistry, Pharmaceu

2017
High spatiotemporal resolution bSSFP imaging of hyperpolarized [1-
    Magnetic resonance in medicine, 2018, Volume: 80, Issue:3

    Topics: Adenocarcinoma; Alanine; Animals; Carbon Isotopes; Image Processing, Computer-Assisted; Lactic Acid;

2018
Polymer nanofiber-based microchips for EGFR mutation analysis of circulating tumor cells in lung adenocarcinoma.
    International journal of nanomedicine, 2018, Volume: 13

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Base Sequence; Carcinoma, Non-Small-Cell Lung; Cell Count; C

2018
Signatures within the esophageal microbiome are associated with host genetics, age, and disease.
    Microbiome, 2018, 12-17, Volume: 6, Issue:1

    Topics: Adenocarcinoma; Age Factors; Aged; Bacteria; Bacteriophages; DNA, Bacterial; DNA, Ribosomal; Esophag

2018
Lactate secreted by cervical cancer cells modulates macrophage phenotype.
    Journal of leukocyte biology, 2019, Volume: 105, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Cell Line, Tumor; Cocultur

2019
Optimal variable flip angle schemes for dynamic acquisition of exchanging hyperpolarized substrates.
    Journal of magnetic resonance (San Diego, Calif. : 1997), 2013, Volume: 234

    Topics: Adenocarcinoma; Algorithms; Animals; Biotransformation; Carbon Isotopes; Computer Simulation; Image

2013
Cross-talk between E. coli strains and a human colorectal adenocarcinoma-derived cell line.
    Scientific reports, 2013, Dec-04, Volume: 3

    Topics: Adenocarcinoma; Caco-2 Cells; Cell Line, Tumor; Citric Acid Cycle; Coculture Techniques; Colorectal

2013
Validation of NCM460 cell model as control in antitumor strategies targeting colon adenocarcinoma metabolic reprogramming: trichostatin A as a case study.
    Biochimica et biophysica acta, 2014, Volume: 1840, Issue:6

    Topics: Adenocarcinoma; Antineoplastic Agents; Citric Acid Cycle; Colonic Neoplasms; Glucose; Glycolysis; Hi

2014
Targeted delivery of 5-fluorouracil to HT-29 cells using high efficient folic acid-conjugated nanoparticles.
    Drug delivery, 2015, Volume: 22, Issue:2

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Biological Transport; Cell Survival; Colonic Neopla

2015
Epithelial cell adhesion molecule aptamer functionalized PLGA-lecithin-curcumin-PEG nanoparticles for targeted drug delivery to human colorectal adenocarcinoma cells.
    International journal of nanomedicine, 2014, Volume: 9

    Topics: Adenocarcinoma; Animals; Antigens, Neoplasm; Antineoplastic Agents; Aptamers, Nucleotide; Cell Adhes

2014
An NMR metabolomics approach for the diagnosis of leptomeningeal carcinomatosis in lung adenocarcinoma cancer patients.
    International journal of cancer, 2015, Jan-01, Volume: 136, Issue:1

    Topics: Adenocarcinoma; Alanine; Area Under Curve; Biomarkers, Tumor; Case-Control Studies; Citric Acid; Cre

2015
Epidermal growth factor receptor (EGFR) signaling regulates global metabolic pathways in EGFR-mutated lung adenocarcinoma.
    The Journal of biological chemistry, 2014, Jul-25, Volume: 289, Issue:30

    Topics: Adenocarcinoma; Aspartate Carbamoyltransferase; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing)

2014
Injectable smart phase-transformation implants for highly efficient in vivo magnetic-hyperthermia regression of tumors.
    Advanced materials (Deerfield Beach, Fla.), 2014, Nov-26, Volume: 26, Issue:44

    Topics: Ablation Techniques; Adenocarcinoma; Animals; Humans; Hyperthermia, Induced; Lactic Acid; Magnetic F

2014
Theranostic Photosensitive Nanoparticles for Lymph Node Metastasis of Gastric Cancer.
    Annals of surgical oncology, 2015, Volume: 22 Suppl 3

    Topics: Adenocarcinoma; Animals; Apoptosis; Cell Proliferation; Coloring Agents; Drug Delivery Systems; Fluo

2015
Signaling through the Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Axis Is Responsible for Aerobic Glycolysis mediated by Glucose Transporter in Epidermal Growth Factor Receptor (EGFR)-mutated Lung Adenocarcinoma.
    The Journal of biological chemistry, 2015, Jul-10, Volume: 290, Issue:28

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Aerobiosis; Cell Line, Tumor; Cell Proliferation; ErbB Recep

2015
SN-38 active loading in poly(lactic-co-glycolic acid) nanoparticles and assessment of their anticancer properties on COLO-205 human colon adenocarcinoma cells.
    Journal of microencapsulation, 2015, Volume: 32, Issue:8

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Line, Tumor; Cell P

2015
STAT3:FOXM1 and MCT1 drive uterine cervix carcinoma fitness to a lactate-rich microenvironment.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:4

    Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Cell Cycle Proteins; Cervix Uteri; Female; Forkhe

2016
NMR metabolomics highlights sphingosine kinase-1 as a new molecular switch in the orchestration of aberrant metabolic phenotype in cancer cells.
    Molecular oncology, 2017, Volume: 11, Issue:5

    Topics: Adenocarcinoma; Animals; Carbon Dioxide; Cell Cycle Proteins; Cell Line, Tumor; Female; Glucose; Glu

2017
Hyperpolarized 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading.
    Cancer research, 2008, Oct-15, Volume: 68, Issue:20

    Topics: Adenocarcinoma; Alanine; Animals; Biomarkers, Tumor; Carbon Isotopes; Disease Models, Animal; Lactic

2008
Hyperpolarized 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading.
    Cancer research, 2008, Oct-15, Volume: 68, Issue:20

    Topics: Adenocarcinoma; Alanine; Animals; Biomarkers, Tumor; Carbon Isotopes; Disease Models, Animal; Lactic

2008
Hyperpolarized 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading.
    Cancer research, 2008, Oct-15, Volume: 68, Issue:20

    Topics: Adenocarcinoma; Alanine; Animals; Biomarkers, Tumor; Carbon Isotopes; Disease Models, Animal; Lactic

2008
Hyperpolarized 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading.
    Cancer research, 2008, Oct-15, Volume: 68, Issue:20

    Topics: Adenocarcinoma; Alanine; Animals; Biomarkers, Tumor; Carbon Isotopes; Disease Models, Animal; Lactic

2008
Nanoparticle-mediated simultaneous and targeted delivery of paclitaxel and tariquidar overcomes tumor drug resistance.
    Journal of controlled release : official journal of the Controlled Release Society, 2009, May-21, Volume: 136, Issue:1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfam

2009
Improved cellular uptake of chitosan-modified PLGA nanospheres by A549 cells.
    International journal of pharmaceutics, 2009, Dec-01, Volume: 382, Issue:1-2

    Topics: Adenocarcinoma; Biological Transport, Active; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceut

2009
Glycolytic pyruvate regulates P-Glycoprotein expression in multicellular tumor spheroids via modulation of the intracellular redox state.
    Journal of cellular biochemistry, 2010, Feb-01, Volume: 109, Issue:2

    Topics: Adenocarcinoma; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1

2010
Cellular uptake mechanisms and intracellular distributions of polysorbate 80-modified poly (D,L-lactide-co-glycolide) nanospheres for gene delivery.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2010, Volume: 75, Issue:2

    Topics: Adenocarcinoma; Cell Line, Tumor; Clathrin; DNA; Endocytosis; Gene Transfer Techniques; Genetic Vect

2010
Nanoparticulate delivery of novel drug combination regimens for the chemoprevention of colon cancer.
    International journal of oncology, 2010, Volume: 37, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Calcium; Cell Line, Tumor;

2010
Reconstitutable charged polymeric (PLGA)(2)-b-PEI micelles for gene therapeutics delivery.
    Biomaterials, 2011, Volume: 32, Issue:15

    Topics: Adenocarcinoma; Breast Neoplasms; Cell Line, Tumor; DNA; Female; Gene Transfer Techniques; Genetic T

2011
Preparation and in vitro evaluation of meloxicam-loaded PLGA nanoparticles on HT-29 human colon adenocarcinoma cells.
    Drug development and industrial pharmacy, 2012, Volume: 38, Issue:9

    Topics: Adenocarcinoma; Antineoplastic Agents; Biological Transport; Cell Survival; Chemistry, Pharmaceutica

2012
Poly-lactic-glycolic-acid surface nanotopographies selectively decrease breast adenocarcinoma cell functions.
    Nanotechnology, 2012, Apr-20, Volume: 23, Issue:15

    Topics: Adenocarcinoma; Apoptosis; Breast; Breast Neoplasms; Cell Adhesion; Cell Count; Cell Line, Tumor; Ce

2012
A new apparatus and surgical technique for the dual perfusion of human tumor xenografts in situ in nude rats.
    Comparative medicine, 2012, Volume: 62, Issue:2

    Topics: Adenocarcinoma; Animals; Artificial Organs; Blood Glucose; Carbon Dioxide; Cell Proliferation; Colon

2012
Coencapsulation of tumor lysate and CpG-ODN in PLGA-microspheres enables successful immunotherapy of prostate carcinoma in TRAMP mice.
    Journal of controlled release : official journal of the Controlled Release Society, 2012, Aug-20, Volume: 162, Issue:1

    Topics: Adenocarcinoma; Adjuvants, Immunologic; Animals; Cell Line; Drug Carriers; Humans; Immunization; Lac

2012
Poly (lactide-co-glycolide) encapsulated extract of Phytolacca decandra demonstrates better intervention against induced lung adenocarcinoma in mice and on A549 cells.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2012, Sep-29, Volume: 47, Issue:2

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antineoplastic Agents; Arsenites; bcl-2-Associated

2012
Expression of pyruvate dehydrogenase kinase-1 in gastric cancer as a potential therapeutic target.
    International journal of oncology, 2013, Volume: 42, Issue:1

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Blotting, Western;

2013
A rapid method for direct detection of metabolic conversion and magnetization exchange with application to hyperpolarized substrates.
    Journal of magnetic resonance (San Diego, Calif. : 1997), 2012, Volume: 225

    Topics: Adenocarcinoma; Algorithms; Animals; Electromagnetic Fields; Humans; Kinetics; L-Lactate Dehydrogena

2012
1H HR-MAS NMR spectroscopy of tumor-induced local metabolic "field-effects" enables colorectal cancer staging and prognostication.
    Journal of proteome research, 2013, Feb-01, Volume: 12, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Amino Acids; Biomarkers, Tumor; Cell Transformation,

2013
[Effect of co-inhibition of MCT1 gene and NHE1 gene on proliferation and growth of human lung adenocarcinoma cells].
    Ai zheng = Aizheng = Chinese journal of cancer, 2002, Volume: 21, Issue:7

    Topics: Adenocarcinoma; Animals; Cell Cycle; Cell Division; Disease Models, Animal; DNA, Antisense; Humans;

2002
Metabolic classification of human rectal adenocarcinomas: a novel guideline for clinical oncologists?
    Journal of cancer research and clinical oncology, 2003, Volume: 129, Issue:6

    Topics: Adenocarcinoma; Adenosine Triphosphate; Aged; Aged, 80 and over; Biopsy; Female; Humans; Lactic Acid

2003
DIAGNOSTIC SIGNIFICANCE OF URINARY LACTIC ACID DEHYDROGENASE.
    The Journal of urology, 1964, Volume: 91

    Topics: Adenocarcinoma; Albuminuria; Carcinoma, Papillary; Carcinoma, Transitional Cell; Clinical Enzyme Tes

1964
Regulation of butyrate uptake in Caco-2 cells by phorbol 12-myristate 13-acetate.
    American journal of physiology. Gastrointestinal and liver physiology, 2004, Volume: 286, Issue:2

    Topics: Adenocarcinoma; Butyric Acid; Caco-2 Cells; Carcinogens; Colonic Neoplasms; Drug Administration Sche

2004
In vitro proton magnetic resonance spectroscopic lactate and choline measurements, 18F-FDG uptake, and prognosis in patients with lung adenocarcinoma.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2004, Volume: 45, Issue:8

    Topics: Adenocarcinoma; Aged; Choline; Disease-Free Survival; Female; Fluorodeoxyglucose F18; Humans; Japan;

2004
[Action of dehydrase of lactic acid on the growth of mammary adenocarcinoma of mice].
    Bulletin der Schweizerischen Akademie der Medizinischen Wissenschaften, 1950, Volume: 6, Issue:2

    Topics: Adenocarcinoma; Animals; Lactic Acid; Mice; Neoplasms; Physiological Phenomena

1950
Comparison of metabolic pathways between cancer cells and stromal cells in colorectal carcinomas: a metabolic survival role for tumor-associated stroma.
    Cancer research, 2006, Jan-15, Volume: 66, Issue:2

    Topics: Adenocarcinoma; Cell Cycle Proteins; Cell Hypoxia; Cell Proliferation; Cell Survival; Colon; Colorec

2006
Therapeutic efficacy of DNA-loaded PLGA microspheres in tumor-bearing mice.
    Archives of pharmacal research, 2007, Volume: 30, Issue:8

    Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Combined Modality Therap

2007
Metabolic imaging in tumours by means of bioluminescence.
    British journal of cancer, 1995, Volume: 72, Issue:5

    Topics: Adenocarcinoma; Adenosine Triphosphate; Animals; Carcinoma, Squamous Cell; Cell Death; Colorectal Ne

1995
Effects of antitumor agents on 3H-2-deoxyglucose uptake in tumor cells and their relationship with the main targets of the antitumor agents.
    Annals of nuclear medicine, 1997, Volume: 11, Issue:3

    Topics: 2,4-Dinitrophenol; Adenocarcinoma; Adenosine Triphosphate; Antineoplastic Agents; Cisplatin; Deoxygl

1997
In vitro influences between pancreatic adenocarcinoma cells and pancreatic islets.
    The Journal of surgical research, 1998, Volume: 79, Issue:1

    Topics: Adenocarcinoma; Animals; Cell Division; Coculture Techniques; Glucose; Humans; Insulin; Insulin Secr

1998
Cytostatic effect of polyethylene glycol on human colonic adenocarcinoma cells.
    International journal of cancer, 2001, Apr-01, Volume: 92, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Caco-2 Cells; Cell Differentiation; Cell Division;

2001
Neoadjuvant therapy with interleukin-12-loaded polylactic acid microspheres reduces local recurrence and distant metastases.
    Surgery, 2001, Volume: 130, Issue:3

    Topics: Adenocarcinoma; Adjuvants, Immunologic; Animals; Immunity; Injections, Intralesional; Interleukin-12

2001
Evaluation of cisplatin in combination with a biologic response modifier in a murine mammary carcinoma model.
    Cancer investigation, 2002, Volume: 20, Issue:4

    Topics: Adenocarcinoma; Adjuvants, Immunologic; Animals; Antineoplastic Agents; Bile; Cisplatin; Delayed-Act

2002
Low light level in vitro monitoring of cellular and antigen-antibody reactions using a photon detection camera system--new perspectives for clinical diagnosis and research.
    Klinische Wochenschrift, 1990, Jan-04, Volume: 68, Issue:1

    Topics: Adenocarcinoma; Adenosine Triphosphate; Animals; Antigen-Antibody Reactions; Blood Glucose; Cell Lin

1990
Metabolic substrate utilization by a tumour cell line which induces cachexia in vivo.
    British journal of cancer, 1986, Volume: 54, Issue:4

    Topics: Adenocarcinoma; Animals; Cachexia; Cell Line; Colonic Neoplasms; Glucose; Ketone Bodies; Lactates; L

1986
[Administration of mitomycin-C with an inactivator].
    Nihon Gan Chiryo Gakkai shi, 1985, Apr-20, Volume: 20, Issue:3

    Topics: Adenocarcinoma; Animals; Antibiotics, Antineoplastic; Drug Therapy, Combination; Humans; Lactates; L

1985