Page last updated: 2024-10-17

lactic acid and Adenocarcinoma of Lung

lactic acid has been researched along with Adenocarcinoma of Lung in 12 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Adenocarcinoma of Lung: A carcinoma originating in the lung and the most common lung cancer type in never-smokers. Malignant cells exhibit distinct features such as glandular epithelial, or tubular morphology. Mutations in KRAS, EGFR, BRAF, and ERBB2 genes are associated with this cancer.

Research Excerpts

ExcerptRelevanceReference
"In the treatment of lung adenocarcinoma, targeting PFKFB3 would be a promising therapeutic strategy."1.48Expression of PFKFB3 and Ki67 in lung adenocarcinomas and targeting PFKFB3 as a therapeutic strategy. ( Ke, H; Li, X; Liu, J; Liu, Y; Qian, L; Tian, W; Yao, C; Zhang, J, 2018)
") Thus, overall results suggest that nano-encapsulation of PD (NPD) increases drug bioavailability and thereby has a better chemo-preventive action against lung cancer in vivo and on A549 cells in vitro than that of PD."1.38Poly (lactide-co-glycolide) encapsulated extract of Phytolacca decandra demonstrates better intervention against induced lung adenocarcinoma in mice and on A549 cells. ( Bhadra, K; Das, J; Das, S; Khuda-Bukhsh, AR; Samadder, A, 2012)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (41.67)24.3611
2020's7 (58.33)2.80

Authors

AuthorsStudies
Zhao, F1
Wang, Z1
Li, Z2
Liu, S1
Li, S4
Shang, S2
Wang, MZ2
Xing, Z2
He, N2
Guo, Z1
Hu, L1
Wang, Q1
Wang, Y2
Liu, XP1
Chen, C1
Hu, W1
Chen, Z1
Song, Y1
Li, P1
Gao, W1
Zhao, M1
Huang, C1
Yang, L1
Pan, B1
Yang, S1
Chang, J1
Jin, Y1
Zhao, G1
Yue, D1
Qie, S1
Ren, L1
Wang, M1
He, T1
Meng, D1
Lv, W1
Ye, J1
Cheng, L1
Hu, J1
Flint, LE1
Hamm, G1
Ready, JD1
Ling, S1
Duckett, CJ1
Cross, NA1
Cole, LM1
Smith, DP1
Goodwin, RJA1
Clench, MR1
Li, X1
Liu, J1
Qian, L1
Ke, H1
Yao, C1
Tian, W1
Liu, Y1
Zhang, J1
Jiang, W1
Wang, H1
Cui, Y1
Lei, Y1
Xu, D1
Jiang, N1
Chen, Y1
Sun, Y1
Zhang, Y1
Cao, J1
Ke, Z1
Liu, N1
Luo, J1
Kuang, D1
Xu, S1
Duan, Y1
Xia, Y1
Wei, Z1
Xie, X1
Yin, B1
Chen, F1
Luo, S1
Liu, H1
Wang, J1
Jiang, K1
Gong, F1
Tang, ZH1
Cheng, X1
Li, H1
Laurence, A1
Wang, G1
Yang, XP1
Makinoshima, H1
Takita, M1
Saruwatari, K1
Umemura, S1
Obata, Y1
Ishii, G1
Matsumoto, S1
Sugiyama, E1
Ochiai, A1
Abe, R1
Goto, K1
Esumi, H1
Tsuchihara, K1
Das, J1
Das, S1
Samadder, A1
Bhadra, K1
Khuda-Bukhsh, AR1

Other Studies

12 other studies available for lactic acid and Adenocarcinoma of Lung

ArticleYear
Identifying a lactic acid metabolism-related gene signature contributes to predicting prognosis, immunotherapy efficacy, and tumor microenvironment of lung adenocarcinoma.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Adenocarcinoma of Lung; Erlotinib Hydrochloride; Etoposide; Gefitinib; Humans; Immunologic Factors;

2022
Lactate regulators contribute to tumor microenvironment and predict prognosis in lung adenocarcinoma.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Adenocarcinoma of Lung; Humans; Lactic Acid; Lung Neoplasms; Programmed Cell Death 1 Receptor; Tumor

2022
Lactate regulators contribute to tumor microenvironment and predict prognosis in lung adenocarcinoma.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Adenocarcinoma of Lung; Humans; Lactic Acid; Lung Neoplasms; Programmed Cell Death 1 Receptor; Tumor

2022
Lactate regulators contribute to tumor microenvironment and predict prognosis in lung adenocarcinoma.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Adenocarcinoma of Lung; Humans; Lactic Acid; Lung Neoplasms; Programmed Cell Death 1 Receptor; Tumor

2022
Lactate regulators contribute to tumor microenvironment and predict prognosis in lung adenocarcinoma.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Adenocarcinoma of Lung; Humans; Lactic Acid; Lung Neoplasms; Programmed Cell Death 1 Receptor; Tumor

2022
Molecular Characterization and Prognosis of Lactate-Related Genes in Lung Adenocarcinoma.
    Current oncology (Toronto, Ont.), 2023, 02-27, Volume: 30, Issue:3

    Topics: Adenocarcinoma of Lung; DNA Copy Number Variations; Humans; Lactic Acid; Lung Neoplasms; Prognosis;

2023
GRIN2D knockdown suppresses the progression of lung adenocarcinoma by regulating the E2F signalling pathway.
    Cellular signalling, 2023, Volume: 107

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Cell Proliferation; Gene Expression Regulation, Neoplastic;

2023
SYVN1-mediated ubiquitylation directs localization of MCT4 in the plasma membrane to promote the progression of lung adenocarcinoma.
    Cell death & disease, 2023, 10-10, Volume: 14, Issue:10

    Topics: Adenocarcinoma of Lung; Animals; Cell Membrane; Humans; Lactic Acid; Mice; Monocarboxylic Acid Trans

2023
BZW2 Modulates Lung Adenocarcinoma Progression through Glycolysis-Mediated IDH3G Lactylation Modification.
    Journal of proteome research, 2023, 12-01, Volume: 22, Issue:12

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Cell Line, Tumor; Cell Proliferation; Gene Expressi

2023
Characterization of an Aggregated Three-Dimensional Cell Culture Model by Multimodal Mass Spectrometry Imaging.
    Analytical chemistry, 2020, 09-15, Volume: 92, Issue:18

    Topics: Adenocarcinoma of Lung; Citric Acid; Glutamine; Humans; Lactic Acid; Lung Neoplasms; Multimodal Imag

2020
Expression of PFKFB3 and Ki67 in lung adenocarcinomas and targeting PFKFB3 as a therapeutic strategy.
    Molecular and cellular biochemistry, 2018, Volume: 445, Issue:1-2

    Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Adult; Aged; Aged, 80 and over; Apoptosis; Bioma

2018
Polymer nanofiber-based microchips for EGFR mutation analysis of circulating tumor cells in lung adenocarcinoma.
    International journal of nanomedicine, 2018, Volume: 13

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Base Sequence; Carcinoma, Non-Small-Cell Lung; Cell Count; C

2018
Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2α-mediated tumor progression.
    The Journal of clinical investigation, 2019, 02-01, Volume: 129, Issue:2

    Topics: Adenocarcinoma of Lung; Animals; Basic Helix-Loop-Helix Transcription Factors; Female; Gene Expressi

2019
Signaling through the Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Axis Is Responsible for Aerobic Glycolysis mediated by Glucose Transporter in Epidermal Growth Factor Receptor (EGFR)-mutated Lung Adenocarcinoma.
    The Journal of biological chemistry, 2015, Jul-10, Volume: 290, Issue:28

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Aerobiosis; Cell Line, Tumor; Cell Proliferation; ErbB Recep

2015
Poly (lactide-co-glycolide) encapsulated extract of Phytolacca decandra demonstrates better intervention against induced lung adenocarcinoma in mice and on A549 cells.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2012, Sep-29, Volume: 47, Issue:2

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antineoplastic Agents; Arsenites; bcl-2-Associated

2012