lactic acid has been researched along with Acute Lung Injury in 17 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Acute Lung Injury: A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our target was to show the role of high mobility group box-1/receptor for (HMGB1/RAGE) interaction in feces intraperitoneal injection procedure (FIP)-induced acute lung injury (ALI) pathophysiology, to investigate the effect of papaverine on RAGE associated NF-κB pathway by determining the level of soluble RAGE (sRAGE) and HMGB1, and to support this hypothesis by evaluating inflammatory biochemical, oxidative stress markers, Hounsfield unit (HU) value in computed tomography (CT), and histo-pathological results." | 8.31 | Demonstration of ameliorating effect of papaverine in sepsis-induced acute lung injury on rat model through radiology and histology. ( Elgörmüş, ÇS; Erbaş, O; Gür, SG; Özkul, B; Sever, İH; Yiğittürk, G, 2023) |
| "Our target was to show the role of high mobility group box-1/receptor for (HMGB1/RAGE) interaction in feces intraperitoneal injection procedure (FIP)-induced acute lung injury (ALI) pathophysiology, to investigate the effect of papaverine on RAGE associated NF-κB pathway by determining the level of soluble RAGE (sRAGE) and HMGB1, and to support this hypothesis by evaluating inflammatory biochemical, oxidative stress markers, Hounsfield unit (HU) value in computed tomography (CT), and histo-pathological results." | 4.31 | Demonstration of ameliorating effect of papaverine in sepsis-induced acute lung injury on rat model through radiology and histology. ( Elgörmüş, ÇS; Erbaş, O; Gür, SG; Özkul, B; Sever, İH; Yiğittürk, G, 2023) |
| "Alveolar inflammation is a hallmark of acute lung injury (ALI), and its clinical correlate is acute respiratory distress syndrome-and it is as a result of interactions between alveolar type II cells (ATII) and alveolar macrophages (AM)." | 1.91 | Lactate produced by alveolar type II cells suppresses inflammatory alveolar macrophages in acute lung injury. ( Allawzi, A; Burns, N; Graham, J; Nozik, ES; Roy, RM; Rubio, V; Stenmark, K; Sul, C; Tuder, RM; Vohwinkel, CU, 2023) |
| "Lactic acid and ATP were also tested." | 1.72 | WIN55212-2 alleviates acute lung injury by inhibiting macrophage glycolysis through the miR-29b-3p/FOXO3/PFKFB3 axis. ( Guo, H; He, Q; Yin, J; Zou, B, 2022) |
| "Hypoxemia is one of the most common pathological processes in various clinical diseases." | 1.48 | High-performance reoxygenation from PLGA-PEG/PFOB emulsions: a feedback relationship between ROS and HIF-1α. ( He, D; Huang, G; Li, N; Shen, X; Wang, J; Wang, R; Zhu, J, 2018) |
| "This experimental protocol of hemorrhagic shock and fluid resuscitation in Landrace-Large White swine may be useful for future study of hemorrhagic shock and acute lung injury." | 1.37 | A model of hemorrhagic shock and acute lung injury in Landrace-Large White Swine. ( Agrogiannis, GD; Balkamou, XA; Demestiha, TD; Pantazopoulos, IN; Rokas, GI; Skandalakis, PN; Stroumpoulis, KI; Troupis, GT; Xanthos, TT, 2011) |
| "Heatstroke was induced by putting the animals in a folded heating pad of 42°C for 68 minutes controlled by circulating hot water." | 1.36 | Inhibition of acute lung inflammation and injury is a target of brain cooling after heatstroke injury. ( Ching-Ping, C; Hsi-Hsing, Y; Juei-Tang, C; Lin, MT, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 10 (58.82) | 24.3611 |
| 2020's | 6 (35.29) | 2.80 |
| Authors | Studies |
|---|---|
| He, Q | 1 |
| Yin, J | 1 |
| Zou, B | 1 |
| Guo, H | 1 |
| Du, N | 1 |
| Lin, H | 1 |
| Zhang, A | 1 |
| Cao, C | 1 |
| Hu, X | 1 |
| Zhang, J | 1 |
| Wang, L | 1 |
| Pan, X | 1 |
| Zhu, Y | 1 |
| Qian, F | 1 |
| Wang, Y | 1 |
| Zhao, D | 1 |
| Liu, M | 1 |
| Huang, Y | 1 |
| Özkul, B | 1 |
| Sever, İH | 1 |
| Yiğittürk, G | 1 |
| Elgörmüş, ÇS | 1 |
| Gür, SG | 1 |
| Erbaş, O | 1 |
| Roy, RM | 1 |
| Allawzi, A | 1 |
| Burns, N | 1 |
| Sul, C | 1 |
| Rubio, V | 1 |
| Graham, J | 1 |
| Stenmark, K | 1 |
| Nozik, ES | 1 |
| Tuder, RM | 1 |
| Vohwinkel, CU | 1 |
| Wang, J | 2 |
| Applefeld, WN | 1 |
| Sun, J | 1 |
| Solomon, SB | 1 |
| Feng, J | 1 |
| Couse, ZG | 1 |
| Risoleo, TF | 1 |
| Danner, RL | 1 |
| Tejero, J | 1 |
| Lertora, J | 1 |
| Alipour, E | 1 |
| Basu, S | 1 |
| Sachdev, V | 1 |
| Kim-Shapiro, DB | 1 |
| Gladwin, MT | 1 |
| Klein, HG | 1 |
| Natanson, C | 1 |
| Gong, Y | 1 |
| Lan, H | 1 |
| Yu, Z | 1 |
| Wang, M | 1 |
| Wang, S | 1 |
| Chen, Y | 1 |
| Rao, H | 1 |
| Li, J | 2 |
| Sheng, Z | 1 |
| Shao, J | 1 |
| Pourfathi, M | 2 |
| Cereda, M | 1 |
| Chatterjee, S | 1 |
| Xin, Y | 2 |
| Kadlecek, S | 1 |
| Duncan, I | 1 |
| Hamedani, H | 2 |
| Siddiqui, S | 1 |
| Profka, H | 2 |
| Ehrich, J | 1 |
| Ruppert, K | 2 |
| Rizi, RR | 2 |
| Wang, R | 1 |
| Li, N | 1 |
| Shen, X | 1 |
| Huang, G | 1 |
| Zhu, J | 1 |
| He, D | 1 |
| Li, M | 1 |
| Li, G | 1 |
| Yu, B | 1 |
| Luo, Y | 1 |
| Li, Q | 1 |
| Yu, TC | 1 |
| Yang, FL | 1 |
| Hsu, BG | 1 |
| Wu, WT | 1 |
| Chen, SC | 1 |
| Lee, RP | 1 |
| Subeq, YM | 1 |
| Li, Y | 1 |
| Liu, XY | 1 |
| Ma, MM | 1 |
| Qi, ZJ | 1 |
| Zhang, XQ | 1 |
| Li, Z | 1 |
| Cao, GH | 1 |
| Zhu, WW | 1 |
| Wang, XZ | 1 |
| Kadlecek, SJ | 1 |
| Cereda, MF | 1 |
| Siddiqui, SM | 1 |
| Drachman, NA | 1 |
| Rajaei, JN | 1 |
| Hsu, JT | 1 |
| Kan, WH | 1 |
| Hsieh, CH | 1 |
| Choudhry, MA | 1 |
| Bland, KI | 1 |
| Chaudry, IH | 1 |
| Hsi-Hsing, Y | 1 |
| Ching-Ping, C | 1 |
| Juei-Tang, C | 1 |
| Lin, MT | 1 |
| Gryth, D | 1 |
| Rocksén, D | 1 |
| Drobin, D | 1 |
| Druid, H | 1 |
| Weitzberg, E | 1 |
| Bursell, J | 1 |
| Olsson, LG | 1 |
| Arborelius, UP | 1 |
| Jesmin, S | 1 |
| Yamaguchi, N | 1 |
| Zaedi, S | 1 |
| Nusrat Sultana, S | 1 |
| Iwashima, Y | 1 |
| Sawamura, A | 1 |
| Gando, S | 1 |
| Xanthos, TT | 1 |
| Balkamou, XA | 1 |
| Stroumpoulis, KI | 1 |
| Pantazopoulos, IN | 1 |
| Rokas, GI | 1 |
| Agrogiannis, GD | 1 |
| Troupis, GT | 1 |
| Demestiha, TD | 1 |
| Skandalakis, PN | 1 |
17 other studies available for lactic acid and Acute Lung Injury
| Article | Year |
|---|---|
WIN55212-2 alleviates acute lung injury by inhibiting macrophage glycolysis through the miR-29b-3p/FOXO3/PFKFB3 axis.
Topics: Acute Lung Injury; Animals; Benzoxazines; Glycolysis; Lactic Acid; Lipopolysaccharides; Macrophages; | 2022 |
N-phenethyl-5-phenylpicolinamide alleviates inflammation in acute lung injury by inhibiting HIF-1α/glycolysis/ASIC1a pathway.
Topics: Acute Lung Injury; Animals; Cytokines; Glucose Transporter Type 1; Glycolysis; Granulocyte-Macrophag | 2022 |
Demonstration of ameliorating effect of papaverine in sepsis-induced acute lung injury on rat model through radiology and histology.
Topics: Acute Lung Injury; Animals; C-Reactive Protein; HMGB1 Protein; Lactic Acid; Papaverine; Radiology; R | 2023 |
Lactate produced by alveolar type II cells suppresses inflammatory alveolar macrophages in acute lung injury.
Topics: Acute Lung Injury; Alveolar Epithelial Cells; Animals; Anti-Inflammatory Agents; Cytokines; Humans; | 2023 |
Mechanistic insights into cell-free hemoglobin-induced injury during septic shock.
Topics: Acidosis; Acute Lung Injury; Animals; Blood Pressure; Dogs; Heart Ventricles; Hemoglobins; Iron; Lac | 2021 |
Blockage of glycolysis by targeting PFKFB3 alleviates sepsis-related acute lung injury via suppressing inflammation and apoptosis of alveolar epithelial cells.
Topics: A549 Cells; Acute Lung Injury; Alveolar Epithelial Cells; Animals; Anti-Inflammatory Agents, Non-Ste | 2017 |
Lung Metabolism and Inflammation during Mechanical Ventilation; An Imaging Approach.
Topics: Acute Lung Injury; Animals; Biomarkers; Carbon Isotopes; Disease Models, Animal; Gene Expression; Hu | 2018 |
High-performance reoxygenation from PLGA-PEG/PFOB emulsions: a feedback relationship between ROS and HIF-1α.
Topics: A549 Cells; Acute Lung Injury; Animals; Cell Hypoxia; Cell Survival; Drug Delivery Systems; Emulsion | 2018 |
Activation of Hypoxia-Inducible Factor-1α Via Succinate Dehydrogenase Pathway During Acute Lung Injury Induced by Trauma/Hemorrhagic Shock.
Topics: A549 Cells; Acute Lung Injury; Animals; Blood Gas Analysis; Blotting, Western; Humans; Hypoxia-Induc | 2020 |
Deleterious effects of aggressive rapid crystalloid resuscitation on treatment of hyperinflammatory response and lung injury induced by hemorrhage in aging rats.
Topics: Acute Lung Injury; Aging; Animals; Blood Glucose; Blood Pressure; Body Temperature; Bronchoalveolar | 2014 |
Changes in intestinal microflora in rats with acute respiratory distress syndrome.
Topics: Acute Lung Injury; Amine Oxidase (Copper-Containing); Animals; Biodiversity; Disease Models, Animal; | 2014 |
In vivo imaging of the progression of acute lung injury using hyperpolarized [1-
Topics: Acute Lung Injury; Animals; Carbon Isotopes; Disease Progression; Hydrochloric Acid; Image Processin | 2017 |
Role of extracellular signal-regulated protein kinase (ERK) in 17beta-estradiol-mediated attenuation of lung injury after trauma-hemorrhage.
Topics: Acute Lung Injury; Animals; Biomarkers; Chemokine CXCL1; Chemokine CXCL2; Down-Regulation; Estradiol | 2009 |
Inhibition of acute lung inflammation and injury is a target of brain cooling after heatstroke injury.
Topics: Acute Lung Injury; Animals; Body Temperature Regulation; Brain; Bronchoalveolar Lavage Fluid; Cytoki | 2010 |
Effects of fluid resuscitation with hypertonic saline dextrane or Ringer's acetate after nonhemorrhagic shock caused by pulmonary contusion.
Topics: Acute Lung Injury; Animals; Blood Pressure; Contusions; Dextrans; Disease Models, Animal; Extravascu | 2010 |
Time-dependent expression of endothelin-1 in lungs and the effects of TNF-α blocking peptide on acute lung injury in an endotoxemic rat model.
Topics: Acute Lung Injury; Animals; Blood Gas Analysis; Blood Pressure; Endothelin-1; Endotoxemia; Lactic Ac | 2011 |
A model of hemorrhagic shock and acute lung injury in Landrace-Large White Swine.
Topics: Acute Lung Injury; Animals; Disease Models, Animal; Heart Rate; Hemoglobins; Hydrogen-Ion Concentrat | 2011 |