lactic acid has been researched along with Acute Kidney Injury in 131 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin-associated lactic acidosis (MALA) is a rare adverse effect that has significant morbidity and mortality." | 9.05 | Osmolar-gap in the setting of metformin-associated lactic acidosis: Case report and a literature review highlighting an apparently unusual association. ( Alamin, M; Elshafei, MN; Mohamed, MFH, 2020) |
| "The current practice concerning timing, mode, and dose of renal replacement therapy (RRT) in patients with metformin-associated lactic acidosis (MALA) with renal failure remains unknown." | 8.95 | Serum lactate level and mortality in metformin-associated lactic acidosis requiring renal replacement therapy: a systematic review of case reports and case series. ( Kuo, CC; Ting, IW; Tsai, CW; Wu, JY; Yeh, HC, 2017) |
| "In our data, preadmission metformin use is associated with a significantly larger decrease in lactate after admission with sepsis or septic shock and with reduced mortality in septic shock." | 8.31 | New potential for an old kid on the block: Impact of premorbid metformin use on lactate kinetics, kidney injury and mortality in sepsis and septic shock, an observational study. ( De Decker, K; De Neve, N; Tackaert, T; Van Moorter, N; Van Vlem, B, 2023) |
| " The present study aims to evaluate the factors that may contribute to the decision whether to start RRT or not and the potential impact of the start of RRT on the outcome in patients with severe lactic acidosis (SLA) (lactate ≥5 mmol/L)." | 8.12 | Patients with Severe Lactic Acidosis in the Intensive Care Unit: A Retrospective Study of Contributing Factors and Impact of Renal Replacement Therapy. ( Hoste, EAJ; Kruse, JM; Van Biesen, W; Van De Ginste, L; Vanommeslaeghe, F; Verbeke, F, 2022) |
| "Metformin-associated lactic acidosis (MALA) carries a high mortality rate." | 7.96 | Metformin-associated lactic acidosis: reinforcing learning points. ( Creagh, F; Goonoo, MS; Morris, R; Raithatha, A, 2020) |
| " BJ rats showed markedly reduced glomerular filtration rate (GFR, inulin clearance) associated with intense renal vasoconstriction, hemolysis, hemoglobinuria, reduced glutathione and increased systemic and renal markers of nitro-oxidative stress (Nitrotyrosine)." | 7.85 | Allopurinol attenuates acute kidney injury following Bothrops jararaca envenomation. ( Canale, D; Crajoinas, R; Ferreira, D; Girardi, ACC; Gois, PHF; Malaque, C; Martines, MS; Massola Shimizu, MH; Seguro, AC; Volpini, R, 2017) |
| "Metformin is renally excreted and has been associated with the development of lactic acidosis." | 7.85 | Acute kidney injury, plasma lactate concentrations and lactic acidosis in metformin users: A GoDarts study. ( Connelly, PJ; Donnelly, L; Lonergan, M; Pearson, ER; Soto-Pedre, E; Zhou, K, 2017) |
| "To evaluate the strength of association between lactic acidosis (LA) and well-recognized risk factors for LA, particularly the weight of metformin." | 7.83 | Lactic Acidosis in Diabetic Population: Is Metformin Implicated? Results of a Matched Case-Control Study Performed on the Type 2 Diabetes Population of Grenoble Hospital University. ( Chanoine, S; Giai, J; Lepelley, M; Villier, C; Yahiaoui, N, 2016) |
| "Metformin-induced lactic acidosis is a rare but severe disease for the individual patients." | 7.81 | [Metformin-induced lactic acidosis : Severe symptoms with difficult diagnostics]. ( Brenner, T; Decker, SO; Hofer, S; Siegler, BH; Ulrich, A; Wortmann, M, 2015) |
| "Severe lactic acidosis was frequent in AKI patients treated with RRT." | 7.80 | Severe lactic acidosis in critically ill patients with acute kidney injury treated with renal replacement therapy. ( De Corte, W; De Waele, JJ; Decruyenaere, J; Dhondt, AW; Hoste, EA; Vanholder, R; Vuylsteke, S, 2014) |
| " All cases of lactic acidosis (pH, ≤ 7." | 7.80 | Metformin accumulation: lactic acidosis and high plasmatic metformin levels in a retrospective case series of 66 patients on chronic therapy. ( Giampreti, A; Locatelli, CA; Lonati, D; Manzo, L; Papa, P; Petrolini, VM; Protti, A; Rocchi, L; Rognoni, C; Rolandi, L; Valli, A; Vecchio, S, 2014) |
| " Metformin-associated lactic acidosis may sometimes be life-threatening." | 7.78 | Metformin-associated lactic acidosis following acute kidney injury. Efficacious treatment with continuous renal replacement therapy. ( Dahan, E; Dichtwald, S; Ekstein, MP; Sorkine, P; Weinbroum, AA, 2012) |
| "Early diagnosis of ethylene glycol poisoning is crucial in order to prevent morbidity and mortality." | 7.75 | Ethylene glycol poisoning presenting with a falsely elevated lactate level. ( Desmet, K; Verelst, S; Vermeersch, P, 2009) |
| "We report 4 cases of lactic acidosis in diabetic patients usually treated with metformin." | 7.72 | [Metformin-associated lactic acidosis remains a serious complication of metformin therapy]. ( Giunti, C; Grimaud, D; Ichai, C; Levraut, J; Orban, JC, 2003) |
| "In type II diabetes treated with metformin, lactic acidosis is a rare but severe complication." | 7.72 | [Metformin-associated lactic acidosis precipitated by acute renal failure]. ( Azoulay, E; Galy-Floc'h, M; Mariot, J; Pertek, JP; Vidal, S, 2003) |
| " We observed a patient with nonmetastatic breast cancer who died because of severe lactic acidosis (plasma lactate concentration = 27 mmol/l) after ingestion of 25 g of elemental germanium over a 2-months period." | 7.68 | Abuse of germanium associated with fatal lactic acidosis. ( Iten, PX; Krapf, R; Schaffner, T, 1992) |
| "Metformin was prescribed to 99 patients (61%) ("M+"group) during the hospitalization, 62 patients were in "M-"group." | 5.91 | [Use of metformin in patients with type 2 diabetes and acute myocardial infarction: safety and impact on glycemic control]. ( Korotina, MA; Pochinka, IG; Strongin, LG, 2023) |
| "High uric acid (UA) has been found to be correlated with renal dysfunction in some experimental and clinical studies; however, the study of the dynamic correlation between AKI and UA in severe burns is still lacking." | 5.42 | Elevated serum uric acid after injury correlates with the early acute kidney in severe burns. ( Hu, X; Liang, J; Zhang, P; Zhi, L, 2015) |
| "Metformin-associated lactic acidosis (MALA) is a rare adverse effect that has significant morbidity and mortality." | 5.05 | Osmolar-gap in the setting of metformin-associated lactic acidosis: Case report and a literature review highlighting an apparently unusual association. ( Alamin, M; Elshafei, MN; Mohamed, MFH, 2020) |
| "The current practice concerning timing, mode, and dose of renal replacement therapy (RRT) in patients with metformin-associated lactic acidosis (MALA) with renal failure remains unknown." | 4.95 | Serum lactate level and mortality in metformin-associated lactic acidosis requiring renal replacement therapy: a systematic review of case reports and case series. ( Kuo, CC; Ting, IW; Tsai, CW; Wu, JY; Yeh, HC, 2017) |
| "In our data, preadmission metformin use is associated with a significantly larger decrease in lactate after admission with sepsis or septic shock and with reduced mortality in septic shock." | 4.31 | New potential for an old kid on the block: Impact of premorbid metformin use on lactate kinetics, kidney injury and mortality in sepsis and septic shock, an observational study. ( De Decker, K; De Neve, N; Tackaert, T; Van Moorter, N; Van Vlem, B, 2023) |
| " Hyperuricemia was defined as a serum uric acid level >7 mg/dL for males and >6 mg/dL for females." | 4.12 | Interaction between Hyperuricemia and Admission Lactate Increases the Risk of Acute Kidney Injury in Patients with ST-Segment Elevation Myocardial Infarction. ( He, Y; Hong, X; Huang, W; Liang, D; Lin, Q; Shan, P; Wang, D; Zhou, X; Zhu, Q, 2022) |
| " The present study aims to evaluate the factors that may contribute to the decision whether to start RRT or not and the potential impact of the start of RRT on the outcome in patients with severe lactic acidosis (SLA) (lactate ≥5 mmol/L)." | 4.12 | Patients with Severe Lactic Acidosis in the Intensive Care Unit: A Retrospective Study of Contributing Factors and Impact of Renal Replacement Therapy. ( Hoste, EAJ; Kruse, JM; Van Biesen, W; Van De Ginste, L; Vanommeslaeghe, F; Verbeke, F, 2022) |
| "Metformin-associated lactic acidosis (MALA) carries a high mortality rate." | 3.96 | Metformin-associated lactic acidosis: reinforcing learning points. ( Creagh, F; Goonoo, MS; Morris, R; Raithatha, A, 2020) |
| "The application of iodinated contrast medium has become a risk factor for metformin-associated lactic acidosis (MALA), which leads to the accumulation of metformin in vivo is one of the principal reasons for MALA." | 3.88 | Involvement of organic cation transporter 2 in the metformin-associated increased lactate levels caused by contrast-induced nephropathy. ( Dai, Y; Huo, X; Liu, K; Liu, Z; Ma, X; Meng, Q; Peng, J; Sun, H; Wang, C; Yang, S, 2018) |
| "Frequent causes of high anion gap metabolic acidosis (HAGMA) are lactic acidosis, ketoacidosis and impaired renal function." | 3.88 | High anion gap metabolic acidosis induced by cumulation of ketones, L- and D-lactate, 5-oxoproline and acute renal failure. ( Heireman, L; Helbert, M; Mahieu, B; Piqueur, M; Stroobants, J; Uyttenbroeck, W, 2018) |
| " BJ rats showed markedly reduced glomerular filtration rate (GFR, inulin clearance) associated with intense renal vasoconstriction, hemolysis, hemoglobinuria, reduced glutathione and increased systemic and renal markers of nitro-oxidative stress (Nitrotyrosine)." | 3.85 | Allopurinol attenuates acute kidney injury following Bothrops jararaca envenomation. ( Canale, D; Crajoinas, R; Ferreira, D; Girardi, ACC; Gois, PHF; Malaque, C; Martines, MS; Massola Shimizu, MH; Seguro, AC; Volpini, R, 2017) |
| "Metformin is renally excreted and has been associated with the development of lactic acidosis." | 3.85 | Acute kidney injury, plasma lactate concentrations and lactic acidosis in metformin users: A GoDarts study. ( Connelly, PJ; Donnelly, L; Lonergan, M; Pearson, ER; Soto-Pedre, E; Zhou, K, 2017) |
| "To evaluate the strength of association between lactic acidosis (LA) and well-recognized risk factors for LA, particularly the weight of metformin." | 3.83 | Lactic Acidosis in Diabetic Population: Is Metformin Implicated? Results of a Matched Case-Control Study Performed on the Type 2 Diabetes Population of Grenoble Hospital University. ( Chanoine, S; Giai, J; Lepelley, M; Villier, C; Yahiaoui, N, 2016) |
| "Metformin-induced lactic acidosis is a rare but severe disease for the individual patients." | 3.81 | [Metformin-induced lactic acidosis : Severe symptoms with difficult diagnostics]. ( Brenner, T; Decker, SO; Hofer, S; Siegler, BH; Ulrich, A; Wortmann, M, 2015) |
| " All cases of lactic acidosis (pH, ≤ 7." | 3.80 | Metformin accumulation: lactic acidosis and high plasmatic metformin levels in a retrospective case series of 66 patients on chronic therapy. ( Giampreti, A; Locatelli, CA; Lonati, D; Manzo, L; Papa, P; Petrolini, VM; Protti, A; Rocchi, L; Rognoni, C; Rolandi, L; Valli, A; Vecchio, S, 2014) |
| "Severe lactic acidosis was frequent in AKI patients treated with RRT." | 3.80 | Severe lactic acidosis in critically ill patients with acute kidney injury treated with renal replacement therapy. ( De Corte, W; De Waele, JJ; Decruyenaere, J; Dhondt, AW; Hoste, EA; Vanholder, R; Vuylsteke, S, 2014) |
| " Metformin-associated lactic acidosis may sometimes be life-threatening." | 3.78 | Metformin-associated lactic acidosis following acute kidney injury. Efficacious treatment with continuous renal replacement therapy. ( Dahan, E; Dichtwald, S; Ekstein, MP; Sorkine, P; Weinbroum, AA, 2012) |
| "Early diagnosis of ethylene glycol poisoning is crucial in order to prevent morbidity and mortality." | 3.75 | Ethylene glycol poisoning presenting with a falsely elevated lactate level. ( Desmet, K; Verelst, S; Vermeersch, P, 2009) |
| " His blood gas analysis showed a metabolic acidosis caused by renal failure and lactic acidosis combined with a hypochloraemic alkalosis." | 3.73 | [A mixed acid-base disorder revealing a cystic dystrophy of aberrant pancreatic tissue]. ( Bedock, B; Dumaine, A; Gauclère, V; Legrand, E; Proust, P; Rozière, A; Tayssir, A, 2006) |
| "We report 4 cases of lactic acidosis in diabetic patients usually treated with metformin." | 3.72 | [Metformin-associated lactic acidosis remains a serious complication of metformin therapy]. ( Giunti, C; Grimaud, D; Ichai, C; Levraut, J; Orban, JC, 2003) |
| "In type II diabetes treated with metformin, lactic acidosis is a rare but severe complication." | 3.72 | [Metformin-associated lactic acidosis precipitated by acute renal failure]. ( Azoulay, E; Galy-Floc'h, M; Mariot, J; Pertek, JP; Vidal, S, 2003) |
| " Lactic acidosis occurred in 8 septic patients irrespective of the substitution fluid." | 3.69 | Comparison of a lactate-versus acetate-based hemofiltration replacement fluid in patients with acute renal failure. ( Grabensee, B; Heering, P; Heintzen, M; Manassa, E; Morgera, S; Passlick-Deetjen, J; Szentandrasi, T; Willers, R, 1997) |
| " We observed a patient with nonmetastatic breast cancer who died because of severe lactic acidosis (plasma lactate concentration = 27 mmol/l) after ingestion of 25 g of elemental germanium over a 2-months period." | 3.68 | Abuse of germanium associated with fatal lactic acidosis. ( Iten, PX; Krapf, R; Schaffner, T, 1992) |
| "Ethylene glycol intoxication produces a severe metabolic acidosis with an increased anion gap." | 3.67 | Organic acids in ethylene glycol intoxication. ( Clay, K; Gabow, PA; Lepoff, R; Sullivan, JB, 1986) |
| "New-onset acute kidney injury was observed in 10 patients (6." | 3.30 | Effect of Saline vs Gluconate/Acetate-Buffered Solution vs Lactate-Buffered Solution on Serum Chloride Among Children in the Pediatric Intensive Care Unit: The SPLYT-P Randomized Clinical Trial. ( Gibbons, KS; Kennedy, M; Le Marsney, R; Mattke, A; Raman, S; Schibler, A; Schlapbach, LJ; Trnka, P, 2023) |
| "Acute kidney injury was evident in 21 of 47 patients (47%) 48 h after enrollment." | 2.80 | Fluid resuscitation and standard drug treatment strategies in heatstroke Chinese patients. ( Feihu, Z; Hongjun, K; Hui, L; Liang, P; Qing, S; Yan, Z, 2015) |
| "Peri-operative acute renal failure requiring renal replacement therapy is common (5-30%) after cardiac surgery and associated with a mortality of approximately 50%." | 2.74 | Risk and outcome analysis of renal replacement therapies in patients after cardiac surgery with pre-operatively normal renal function. ( Beiras-Fernandez, A; Briegel, J; Hauer, D; Kaufmann, I; Kilger, E; Kreth, S; Schelling, G; Schmidt, M; Weis, F, 2009) |
| " A volume therapy with exclusively crystalloids or colloids with the chosen colloid hyperoncotic, hyperchloremic HES solution (10% hydroxyethyl starch: 10% Hemohes) or the crystalloid solution with high lactate content (Sterofundin) is neither acceptable nor practicable, even if only due to exceeding the maximum dosage as recommended by the manufacturer." | 2.73 | [The design of the VISEP trial. Critical appraisal]. ( Boldt, J; Engelmann, L; Mertzlufft, F; Sirtl, C; Stuttmann, R; Zander, R, 2007) |
| "Acute renal failure is one of the most frequent and life-threatening complications after cardiac surgery." | 2.44 | Perioperative renal failure: hypoperfusion during cardiopulmonary bypass? ( Ranucci, M, 2007) |
| "Hyperlactatemia is associated with mortality outcomes in patients undergoing CRRT for acute kidney injury." | 1.91 | Hyperlactatemia is a predictor of mortality in patients undergoing continuous renal replacement therapy for acute kidney injury. ( Han, SS; Joo, KW; Kang, MW; Kim, DK; Kim, SG; Kim, YC; Kim, YS; Lee, J; Oh, KH; Yun, D, 2023) |
| "Metformin was prescribed to 99 patients (61%) ("M+"group) during the hospitalization, 62 patients were in "M-"group." | 1.91 | [Use of metformin in patients with type 2 diabetes and acute myocardial infarction: safety and impact on glycemic control]. ( Korotina, MA; Pochinka, IG; Strongin, LG, 2023) |
| "Sepsis has high incidence and fatality rates in intensive care units, often leading to renal failure." | 1.72 | The association between continuous renal replacement therapy as treatment for sepsis-associated acute kidney injury and trend of lactate trajectory as risk factor of 28-day mortality in intensive care units. ( Han, D; Lyu, J; Wang, Z; Xu, F; Zhang, L, 2022) |
| "Hyperlactatemia is a common complication in critically ill patients with high morbidity and mortality." | 1.72 | Characteristics and predictors of ICU-mortality in critically ill patients with hyperlactatemia requiring CRRT: A retrospective cohort study. ( Bai, M; Li, L; Sun, S; Zhang, Q, 2022) |
| "Sepsis is a host response with life-threatening organ dysfunction caused by an infection." | 1.72 | Risk stratification and prognostic value of serum neutrophil gelatinase-associated lipocalin (sNGAL) in sepsis patients. ( Fan, J; He, ZM; Sun, Y; Wu, Y; Yu, C; Zhang, W; Zhou, Y, 2022) |
| "There were 806 trauma patients recorded in the database." | 1.62 | Prehospital Blood Pressure and Lactate are Early Predictors of Acute Kidney Injury After Trauma. ( Iwasaki, Y; Kato, S; Kawashima, S; Kunitatsu, K; Nasu, T; Okishio, Y; Ueda, K, 2021) |
| "Development of AKI after blunt trauma is very complex and multifactorial." | 1.56 | Physiologic risk factors for early acute kidney injury in severely injured patients. ( Bursa, F; Frelich, M; Maca, J; Neiser, J; Petejova, N; Sevcik, P; Sklienka, P; Svagera, Z; Tomaskova, H; Zahorec, R, 2020) |
| "The application of RAI in children with septic shock has not been reported." | 1.56 | Assessment of early renal angina index for prediction of subsequent severe acute kidney injury during septic shock in children. ( Huang, L; Huang, S; Li, W; Li, X; Li, Y; Liu, X; Quan, W; Shi, T; Zhang, L, 2020) |
| "2,584 septic shock patients were enrolled." | 1.56 | Presentation and outcomes of end stage liver disease patients presenting with septic shock to the emergency department. ( Heffner, AC; Okonkwo, E; Rozario, N, 2020) |
| "Development of hypotensive shock or pulmonary edema within 24 hours after enrollment were not related to the volume of fluid administration." | 1.56 | Associations Between Restrictive Fluid Management and Renal Function and Tissue Perfusion in Adults With Severe Falciparum Malaria: A Prospective Observational Study. ( Alam, S; Charunwatthana, P; Day, NPJ; Dey, C; Dondorp, AM; Faiz, MA; Ghose, A; Herdman, MT; Hossain, MA; Ishioka, H; Kingston, HWF; Leopold, SJ; Mahanta, K; Maude, RJ; Mohanty, A; Mohanty, S; Pattnaik, R; Plewes, K; Srinamon, K; White, NJ, 2020) |
| "All 82 patients with diabetic ketoacidosis survived." | 1.51 | Acute Kidney Injury in Critically Ill Children Admitted to the PICU for Diabetic Ketoacidosis. A Retrospective Study. ( Gendler, Y; Kadmon, G; Kaplan, E; Nahum, E; Weissbach, A; Zur, N, 2019) |
| "High uric acid (UA) has been found to be correlated with renal dysfunction in some experimental and clinical studies; however, the study of the dynamic correlation between AKI and UA in severe burns is still lacking." | 1.42 | Elevated serum uric acid after injury correlates with the early acute kidney in severe burns. ( Hu, X; Liang, J; Zhang, P; Zhi, L, 2015) |
| "Complete clinical data of patients with septic shock admitted to emergency intensive care unit (EICU) of Sichuan Provincial People's Hospital from May 1994 to December 2014 were recorded and analyzed." | 1.42 | [Improvement effect of early goal-directed therapy on the prognosis in patients with septic shock]. ( Li, C; Yun, D, 2015) |
| "We identified 423 patients with severe sepsis and electronically recorded continuous hemodynamic data in the prospective observational FINNAKI study." | 1.39 | Hemodynamic variables and progression of acute kidney injury in critically ill patients with severe sepsis: data from the prospective observational FINNAKI study. ( Hautamäki, R; Hovilehto, S; Inkinen, O; Karlsson, S; Kaukonen, KM; Korhonen, AM; Kuitunen, A; Laru-Sompa, R; Pettilä, V; Poukkanen, M; Uusaro, A; Vaara, ST; Wilkman, E, 2013) |
| "The metabolic disorders related to acute renal failure or associated with it, such as liver failure, may affect lactate metabolism, and therefore they are often regarded as limiting factors for the use of lactate-containing fluids in such patients." | 1.33 | Lactate metabolism in acute uremia. ( Ichai, C; Krouzecky, A; Leverve, X; Matejovic, M; Mustafa, I; Novak, I; Rokyta, R, 2005) |
| "CVVH corrects metabolic acidosis in acute renal failure patients through its effect on unmeasured anions, phosphate and chloride." | 1.32 | Impact of continuous veno-venous hemofiltration on acid-base balance. ( Bellomo, R; Morimatsu, H; Rocktäschel, J; Ronco, C; Uchino, S, 2003) |
| "Ten critically ill patients with acute renal failure and stable blood lactate concentrations." | 1.30 | Effect of continuous venovenous hemofiltration with dialysis on lactate clearance in critically ill patients. ( Ciebiera, JP; Grimaud, D; Ichai, C; Jambou, P; Labib, Y; Levraut, J, 1997) |
| "Twelve children (3 days-6 years) with acute renal failure (ARF), positive fluid balance, and lactate acidosis (> 40 mg/dL) were treated by automated peritoneal dialysis (APD) with frequent exchanges of small fill volumes of a hypertonic solution." | 1.30 | Advantages of HCO3 solution with low sodium concentration over standard lactate solutions for acute peritoneal dialysis. ( Castillo, D; Dejaegher, A; Lutz-Dettinger, N; Raes, A; Vande Walle, J, 1997) |
| "In continuous treatment of acute renal failure, hemofiltrate is always available, but it contains only low protein concentrations and after the filtration process, metabolism is rapidly stopped." | 1.30 | Which organic acids does hemofiltrate contain in the presence of acute renal failure? ( Guth, HJ; Jäger, B; Kraatz, G; Panzig, E; Rudolph, PE; Zschiesche, M, 1999) |
| "Postischemic acute renal failure was induced by 1 hr of clamping of the renal vasculature." | 1.27 | Metabolic studies of postischemic acute renal failure in the rat. ( Cowley, RA; Kahng, MW; Trifillis, AL; Trump, BF, 1984) |
| "Models of post-ischemic acute renal failure were prepared in rats." | 1.27 | [Effect of adenosine triphosphate-magnesium chloride administration for post-ischemic acute renal failure (I)]. ( Arao, S; Asahi, T; Handa, T; Kawazoe, S; Nakazawa, T; Shimizu, K; Shiraishi, M; Tanaka, S, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (3.82) | 18.7374 |
| 1990's | 16 (12.21) | 18.2507 |
| 2000's | 19 (14.50) | 29.6817 |
| 2010's | 53 (40.46) | 24.3611 |
| 2020's | 38 (29.01) | 2.80 |
| Authors | Studies |
|---|---|
| Van De Ginste, L | 1 |
| Vanommeslaeghe, F | 1 |
| Hoste, EAJ | 1 |
| Kruse, JM | 1 |
| Van Biesen, W | 1 |
| Verbeke, F | 1 |
| Hao, X | 1 |
| Guo, D | 1 |
| Yuan, X | 1 |
| Xu, B | 1 |
| Wu, Y | 1 |
| Yu, C | 1 |
| Zhou, Y | 1 |
| He, ZM | 1 |
| Zhang, W | 1 |
| Fan, J | 1 |
| Sun, Y | 1 |
| Wang, Z | 1 |
| Zhang, L | 3 |
| Xu, F | 1 |
| Han, D | 1 |
| Lyu, J | 1 |
| Dereli, N | 1 |
| Babayigit, M | 1 |
| Menteş, O | 1 |
| Koç, F | 1 |
| Ari, O | 1 |
| Doğan, E | 1 |
| Onhan, E | 1 |
| Deng, J | 1 |
| Zhong, Q | 1 |
| He, Y | 2 |
| Wang, D | 1 |
| Zhou, X | 1 |
| Zhu, Q | 1 |
| Lin, Q | 1 |
| Hong, X | 1 |
| Huang, W | 1 |
| Shan, P | 1 |
| Liang, D | 1 |
| Li, L | 2 |
| Bai, M | 1 |
| Zhang, Q | 1 |
| Sun, S | 1 |
| Van Moorter, N | 3 |
| Tackaert, T | 3 |
| De Decker, K | 3 |
| Van Vlem, B | 3 |
| De Neve, N | 3 |
| Raman, S | 1 |
| Gibbons, KS | 1 |
| Mattke, A | 1 |
| Schibler, A | 1 |
| Trnka, P | 1 |
| Kennedy, M | 1 |
| Le Marsney, R | 1 |
| Schlapbach, LJ | 1 |
| Kim, SG | 1 |
| Lee, J | 1 |
| Yun, D | 2 |
| Kang, MW | 1 |
| Kim, YC | 1 |
| Kim, DK | 1 |
| Oh, KH | 1 |
| Joo, KW | 1 |
| Kim, YS | 1 |
| Han, SS | 1 |
| Korotina, MA | 1 |
| Pochinka, IG | 1 |
| Strongin, LG | 1 |
| Wu, M | 1 |
| Cui, M | 1 |
| Jiang, A | 1 |
| Sun, R | 1 |
| Liu, M | 2 |
| Pang, X | 1 |
| Wang, H | 1 |
| Song, B | 1 |
| Cho, H | 1 |
| Jung, JY | 1 |
| Yoon, HK | 1 |
| Yang, SM | 1 |
| Lee, HJ | 1 |
| Kim, WH | 1 |
| Jung, CW | 1 |
| Suh, KS | 1 |
| Ren, E | 1 |
| Xiao, H | 1 |
| Li, J | 2 |
| Yu, H | 1 |
| Liu, B | 1 |
| Wang, G | 1 |
| Sun, X | 1 |
| Duan, M | 1 |
| Hang, C | 1 |
| Zhang, G | 1 |
| Wu, C | 1 |
| Li, F | 1 |
| Zhang, H | 2 |
| Zhang, Y | 2 |
| Guo, W | 1 |
| Qi, W | 1 |
| Yin, Q | 1 |
| Zhao, Y | 1 |
| Xie, M | 1 |
| Li, C | 2 |
| An, S | 1 |
| Yao, Y | 1 |
| Hu, H | 1 |
| Wu, J | 2 |
| Sun, M | 1 |
| Deng, Z | 1 |
| Gong, S | 1 |
| Huang, Q | 1 |
| Chen, Z | 1 |
| Zeng, Z | 1 |
| Zhi, HJ | 1 |
| Cui, J | 1 |
| Yuan, MW | 1 |
| Zhao, YN | 1 |
| Zhao, XW | 1 |
| Zhu, TT | 1 |
| Jia, CM | 1 |
| Li, Y | 2 |
| Ishioka, H | 1 |
| Plewes, K | 1 |
| Pattnaik, R | 1 |
| Kingston, HWF | 1 |
| Leopold, SJ | 1 |
| Herdman, MT | 1 |
| Mahanta, K | 1 |
| Mohanty, A | 2 |
| Dey, C | 1 |
| Alam, S | 1 |
| Srinamon, K | 1 |
| Maude, RJ | 1 |
| White, NJ | 1 |
| Day, NPJ | 1 |
| Hossain, MA | 1 |
| Faiz, MA | 1 |
| Charunwatthana, P | 1 |
| Mohanty, S | 1 |
| Ghose, A | 1 |
| Dondorp, AM | 1 |
| Xu, J | 1 |
| Ma, X | 2 |
| Yu, K | 3 |
| Wang, R | 1 |
| Wang, S | 1 |
| Liu, R | 1 |
| Liu, H | 1 |
| Gao, H | 1 |
| Wang, C | 2 |
| Hendrix, RHJ | 1 |
| Ganushchak, YM | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study of Metformin Overdose in Adult Patients Treated at the University Hospital of Nancy: Single-center Descriptive Retrospective Observational Study[NCT04762966] | 50 participants (Anticipated) | Observational | 2021-03-01 | Recruiting | |||
| Transfusion Requirements After Cardiac Surgery: a Randomized Controlled Clinical Trial (TRACS STUDY)[NCT01021631] | Phase 3 | 500 participants (Anticipated) | Interventional | 2009-02-28 | Recruiting | ||
| Effect of the Administration of Melatonin and Metformin on Glycemic Control, Genotoxicity and Cytotoxicity Markers in Patients With Prediabetes: Pilot Study[NCT03848533] | Phase 2 | 42 participants (Anticipated) | Interventional | 2019-08-22 | Recruiting | ||
| Safety of Fluid Resuscitation With Hydroxyethyl Starch 130/0.4 on Blood Coagulation and Renal Functions in Trauma Patients: Multicenter Clinical Trial[NCT03486600] | 392 participants (Anticipated) | Interventional | 2018-04-01 | Not yet recruiting | |||
| Built-in Calculator Optimizes Continuous Veno-venous Hemofiltration Prescription and Improves Therapeutic Quality in Critically-ill Acute Kidney Injury Patients[NCT05638711] | 1 participants (Actual) | Observational | 2019-01-01 | Completed | |||
| A Multi-center, Randomized Controlled Trial of Goal-directed Perfusion in Cardiac Surgery[NCT02250131] | 350 participants (Actual) | Interventional | 2014-10-31 | Terminated | |||
| [NCT01824771] | 15 participants (Actual) | Observational [Patient Registry] | 2013-03-03 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
12 reviews available for lactic acid and Acute Kidney Injury
| Article | Year |
|---|---|
Serum neutrophil gelatinase-associated lipocalin and lactate level during surgery predict acute kidney injury and early allograft dysfunction after liver transplantation.
Topics: Acute Kidney Injury; Acute-Phase Proteins; Allografts; Biomarkers; Humans; Lactic Acid; Lipocalin-2; | 2023 |
Osmolar-gap in the setting of metformin-associated lactic acidosis: Case report and a literature review highlighting an apparently unusual association.
Topics: Acid-Base Imbalance; Acidosis, Lactic; Acute Kidney Injury; Diabetes Mellitus, Type 2; Humans; Hypog | 2020 |
Sugar or Fat? Renal Tubular Metabolism Reviewed in Health and Disease.
Topics: Acute Kidney Injury; Dietary Sugars; Disease Progression; Fatty Acids; Humans; Kidney Tubules; Kidne | 2021 |
Serum lactate level and mortality in metformin-associated lactic acidosis requiring renal replacement therapy: a systematic review of case reports and case series.
Topics: Acidosis, Lactic; Acute Kidney Injury; Adult; Aged; Biomarkers; Female; Humans; Hypoglycemic Agents; | 2017 |
Volume Resuscitation in Patients With High-Voltage Electrical Injuries.
Topics: Acute Kidney Injury; Adult; Burns, Electric; Critical Care; Hemodynamics; Humans; Lactic Acid; Male; | 2018 |
Beyond Mean Arterial Pressure and Lactate: Perfusion End Points for Managing the Shocked Patient.
Topics: Acute Kidney Injury; Arterial Pressure; Biomarkers; Blood Circulation; Carbon Dioxide; Cardiac Outpu | 2019 |
Bicarbonate versus lactate solutions for acute peritoneal dialysis.
Topics: Acute Kidney Injury; Adult; Bicarbonates; Dialysis Solutions; Humans; Lactic Acid; Peritoneal Dialys | 2014 |
Bicarbonate- versus lactate-buffered solutions for acute continuous haemodiafiltration or haemofiltration.
Topics: Acute Kidney Injury; Adult; Bicarbonates; Blood Pressure; Buffers; Creatinine; Dialysis Solutions; H | 2015 |
Bicarbonate versus lactate solutions for acute peritoneal dialysis.
Topics: Acute Kidney Injury; Adult; Bicarbonates; Dialysis Solutions; Humans; Lactic Acid; Peritoneal Dialys | 2010 |
Perioperative renal failure: hypoperfusion during cardiopulmonary bypass?
Topics: Acute Kidney Injury; Cardiopulmonary Bypass; Hematocrit; Humans; Intraoperative Complications; Kidne | 2007 |
Treatment of acute renal failure in intensive care patients.
Topics: Acidosis; Acute Kidney Injury; Bicarbonates; Hemofiltration; Humans; Intensive Care Units; Lactates; | 1996 |
Acid-base balance and replacement solutions in continuous renal replacement therapies.
Topics: Acid-Base Equilibrium; Acute Kidney Injury; Bicarbonates; Buffers; Critical Care; Dialysis Solutions | 1998 |
11 trials available for lactic acid and Acute Kidney Injury
| Article | Year |
|---|---|
Effect of Saline vs Gluconate/Acetate-Buffered Solution vs Lactate-Buffered Solution on Serum Chloride Among Children in the Pediatric Intensive Care Unit: The SPLYT-P Randomized Clinical Trial.
Topics: Acute Kidney Injury; Adult; Child; Child, Preschool; Chlorides; Critical Illness; Fluid Therapy; Glu | 2023 |
Trauma induced acute kidney injury.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Blood Pressure; Creatinine; Disease | 2019 |
High lactate levels are predictors of major complications after cardiac surgery.
Topics: Acute Kidney Injury; Age Factors; Aged; Biomarkers; Brazil; Cardiac Surgical Procedures; Chi-Square | 2013 |
Fluid resuscitation and standard drug treatment strategies in heatstroke Chinese patients.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; China; Extravascular Lung Water; Female; Fluid Therapy | 2015 |
Risk and outcome analysis of renal replacement therapies in patients after cardiac surgery with pre-operatively normal renal function.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Bilirubin; Biomarkers; Cardiac Surgical Procedu | 2009 |
Resuscitation with hydroxyethyl starch improves renal function and lactate clearance in penetrating trauma in a randomized controlled study: the FIRST trial (Fluids in Resuscitation of Severe Trauma).
Topics: Acute Kidney Injury; Adolescent; Adult; Biomarkers; Double-Blind Method; Female; Fluid Therapy; Foll | 2011 |
Cardiovascular outcome in critically ill patients treated with continuous haemofiltration--beneficial effects of bicarbonate-buffered replacement fluids.
Topics: Acute Kidney Injury; Bicarbonates; Buffers; Cardiovascular Diseases; Creatinine; Critical Illness; D | 2002 |
The acid-base effects of continuous hemofiltration with lactate or bicarbonate buffered replacement fluids.
Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Acute Kidney Injury; Adult; Aged; Bicarbonates; Buffers; | 2003 |
[The design of the VISEP trial. Critical appraisal].
Topics: Acute Kidney Injury; Blood Glucose; Colloids; Critical Care; Crystalloid Solutions; Endpoint Determi | 2007 |
Phase II, randomized, controlled trial of high-dose N-acetylcysteine in high-risk cardiac surgery patients.
Topics: Acetylcysteine; Acute Kidney Injury; Aged; Blood Pressure; Cardiac Surgical Procedures; Cardiopulmon | 2007 |
Lactate or bicarbonate for intermittent hemofiltration?
Topics: Acidosis, Lactic; Acute Kidney Injury; Bicarbonates; Buffers; Female; Hemodialysis Solutions; Hemofi | 1991 |
108 other studies available for lactic acid and Acute Kidney Injury
| Article | Year |
|---|---|
Patients with Severe Lactic Acidosis in the Intensive Care Unit: A Retrospective Study of Contributing Factors and Impact of Renal Replacement Therapy.
Topics: Acidosis, Lactic; Acute Kidney Injury; Humans; Hyperlactatemia; Intensive Care Units; Lactic Acid; R | 2022 |
The predictive value of cystatin C combined with lactic acid and uric acid in the occurrence of acute kidney injury in sepsis.
Topics: Acute Kidney Injury; Biomarkers; Creatinine; Cystatin C; Humans; Lactic Acid; Predictive Value of Te | 2022 |
Risk stratification and prognostic value of serum neutrophil gelatinase-associated lipocalin (sNGAL) in sepsis patients.
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Biomarkers; Female; Humans; Lactic Acid; Lipocalin-2; | 2022 |
The association between continuous renal replacement therapy as treatment for sepsis-associated acute kidney injury and trend of lactate trajectory as risk factor of 28-day mortality in intensive care units.
Topics: Acute Kidney Injury; Continuous Renal Replacement Therapy; Female; Humans; Intensive Care Units; Lac | 2022 |
Are we aware of COVID-19-related acute kidney injury in intensive care units?
Topics: Acute Kidney Injury; Age Factors; Aged; Aged, 80 and over; APACHE; COVID-19; Cross Infection; Female | 2022 |
Analysis of prognostic factors for in-hospital mortality in patients with unplanned re-exploration after cardiovascular surgery.
Topics: Acute Kidney Injury; Creatinine; Female; Hospital Mortality; Humans; Lactic Acid; Male; Prognosis; R | 2022 |
Interaction between Hyperuricemia and Admission Lactate Increases the Risk of Acute Kidney Injury in Patients with ST-Segment Elevation Myocardial Infarction.
Topics: Acute Kidney Injury; Female; Humans; Hyperuricemia; Lactic Acid; Male; Risk Factors; ST Elevation My | 2022 |
Characteristics and predictors of ICU-mortality in critically ill patients with hyperlactatemia requiring CRRT: A retrospective cohort study.
Topics: Acute Kidney Injury; Adult; Aged; Continuous Renal Replacement Therapy; Critical Illness; Humans; Hy | 2022 |
New potential for an old kid on the block: Impact of premorbid metformin use on lactate kinetics, kidney injury and mortality in sepsis and septic shock, an observational study.
Topics: Acute Kidney Injury; Humans; Kidney; Lactic Acid; Metformin; Retrospective Studies; Sepsis; Shock, S | 2023 |
New potential for an old kid on the block: Impact of premorbid metformin use on lactate kinetics, kidney injury and mortality in sepsis and septic shock, an observational study.
Topics: Acute Kidney Injury; Humans; Kidney; Lactic Acid; Metformin; Retrospective Studies; Sepsis; Shock, S | 2023 |
New potential for an old kid on the block: Impact of premorbid metformin use on lactate kinetics, kidney injury and mortality in sepsis and septic shock, an observational study.
Topics: Acute Kidney Injury; Humans; Kidney; Lactic Acid; Metformin; Retrospective Studies; Sepsis; Shock, S | 2023 |
New potential for an old kid on the block: Impact of premorbid metformin use on lactate kinetics, kidney injury and mortality in sepsis and septic shock, an observational study.
Topics: Acute Kidney Injury; Humans; Kidney; Lactic Acid; Metformin; Retrospective Studies; Sepsis; Shock, S | 2023 |
Hyperlactatemia is a predictor of mortality in patients undergoing continuous renal replacement therapy for acute kidney injury.
Topics: Acute Kidney Injury; APACHE; Continuous Renal Replacement Therapy; Critical Illness; Humans; Hyperla | 2023 |
[Use of metformin in patients with type 2 diabetes and acute myocardial infarction: safety and impact on glycemic control].
Topics: Acute Kidney Injury; Diabetes Mellitus, Type 2; Glycemic Control; Humans; Hypoglycemic Agents; Lacti | 2023 |
Supramolecularly Engineered Reporters with Superoxide Anion-Triggered Chemiluminescence for Early Diagnosis and Efficient Amelioration of Acute Kidney Injury.
Topics: Acute Kidney Injury; Early Diagnosis; Humans; Lactic Acid; Luminescence; Superoxide Dismutase; Super | 2023 |
CLINICAL CHARACTERISTICS AND PREDICTORS OF MORTALITY DIFFER BETWEEN PULMONARY AND ABDOMINAL SEPSIS.
Topics: Acute Kidney Injury; Adult; Humans; Intraabdominal Infections; Lactic Acid; Lipopolysaccharide Recep | 2023 |
PDHA1 hyperacetylation-mediated lactate overproduction promotes sepsis-induced acute kidney injury via Fis1 lactylation.
Topics: Acute Kidney Injury; Apoptosis; Humans; Lactic Acid; Mitochondrial Proteins; Sepsis; Sirtuin 3 | 2023 |
Predictive performance of renal resistive index, semiquantitative power Doppler ultrasound score and renal venous Doppler waveform pattern for acute kidney injury in critically ill patients and prediction model establishment: a prospective observational s
Topics: Acute Kidney Injury; Critical Illness; Humans; Lactic Acid; Ultrasonography; Ultrasonography, Dopple | 2023 |
Associations Between Restrictive Fluid Management and Renal Function and Tissue Perfusion in Adults With Severe Falciparum Malaria: A Prospective Observational Study.
Topics: Acute Kidney Injury; Adult; Female; Fluid Therapy; Humans; Kidney Function Tests; Lactic Acid; Malar | 2020 |
Lactate up-regulates the expression of PD-L1 in kidney and causes immunosuppression in septic Acute Renal Injury.
Topics: Acute Kidney Injury; Animals; Apoptosis; B7-H1 Antigen; Disease Models, Animal; Epithelial Cells; Im | 2021 |
Oxygen delivery, oxygen consumption and decreased kidney function after cardiopulmonary bypass.
Topics: Acute Kidney Injury; Aged; Area Under Curve; Cardiopulmonary Bypass; Coronary Artery Disease; Female | 2019 |
Presentation and outcomes of end stage liver disease patients presenting with septic shock to the emergency department.
Topics: Acute Kidney Injury; Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; APACHE; Body Temp | 2020 |
Resuscitation with albumin using BET formula keeps at bay fluid administration in burned patients. An observational study.
Topics: Acute Kidney Injury; Adult; Aged; Albumins; Body Surface Area; Burns; Colloids; Disease Progression; | 2020 |
Acute Kidney Injury in Neonates with Perinatal Asphyxia Receiving Therapeutic Hypothermia.
Topics: Acute Kidney Injury; Asphyxia Neonatorum; Biomarkers; Female; Fetal Blood; Humans; Hydrogen-Ion Conc | 2021 |
When Should Clinicians Act on Non-Statistically Significant Results From Clinical Trials?
Topics: Acute Kidney Injury; Coronary Angiography; Evidence-Based Practice; Fluid Therapy; Humans; Hydroxyet | 2020 |
Methylglyoxal and D-lactate in cisplatin-induced acute kidney injury: Investigation of the potential mechanism via fluorogenic derivatization liquid chromatography-tandem mass spectrometry (FD-LC-MS/MS) proteomic analysis.
Topics: Acute Kidney Injury; Animals; Antineoplastic Agents; Chromatography, Liquid; Cisplatin; Female; Kidn | 2020 |
Altered proximal tubular cell glucose metabolism during acute kidney injury is associated with mortality.
Topics: Acute Kidney Injury; Adult; Aged; Animals; Critical Illness; Female; Gluconeogenesis; Glucose; Human | 2020 |
Assessment of early renal angina index for prediction of subsequent severe acute kidney injury during septic shock in children.
Topics: Acute Kidney Injury; Adolescent; Child; Child, Preschool; Creatinine; Female; Humans; Infant; Intens | 2020 |
Metformin-associated lactic acidosis: reinforcing learning points.
Topics: Acidosis, Lactic; Acute Kidney Injury; Bicarbonates; Continuous Renal Replacement Therapy; Diabetes | 2020 |
Bundled care in acute kidney injury in critically ill patients, a before-after educational intervention study.
Topics: Acute Kidney Injury; Adult; Aged; Arterial Pressure; Critical Illness; Deprescriptions; Disease Prog | 2020 |
Utilization of Deep Learning for Subphenotype Identification in Sepsis-Associated Acute Kidney Injury.
Topics: Acute Kidney Injury; Aged; Alanine Transaminase; Bilirubin; Blood Urea Nitrogen; Comorbidity; Creati | 2020 |
Physiologic risk factors for early acute kidney injury in severely injured patients.
Topics: Acute Kidney Injury; Adult; Biomarkers; Humans; Interleukin-6; Lactic Acid; Lipocalin-2; Myoglobin; | 2020 |
Combination of biomarker with clinical risk factors for prediction of severe acute kidney injury in critically ill patients.
Topics: Acute Kidney Injury; Age Factors; Aged; Aged, 80 and over; Biomarkers; Clinical Decision Rules; Cont | 2020 |
Inhibition of aerobic glycolysis alleviates sepsis‑induced acute kidney injury by promoting lactate/Sirtuin 3/AMPK‑regulated autophagy.
Topics: Acute Kidney Injury; AMP-Activated Protein Kinases; Animals; Autophagy; Deoxyglucose; Glycolysis; La | 2021 |
Impact of left ventricular function on tissue perfusion and renal outcomes in patients with sepsis.
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Female; Glomerular Filtration Rate; Humans; Lactic Aci | 2021 |
Prehospital Blood Pressure and Lactate are Early Predictors of Acute Kidney Injury After Trauma.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Blood Pressure; Female; Humans; Japan; Lactic A | 2021 |
Acute intensive care unit resuscitation of severely injured trauma patients: Do we need a new strategy?
Topics: Abbreviated Injury Scale; Acute Kidney Injury; Adult; Crystalloid Solutions; Duration of Therapy; Fe | 2021 |
Risk factors associated to hospital mortality in patients with acute kidney injury on hemodialysis.
Topics: Acute Kidney Injury; Aged; Arterial Pressure; Cohort Studies; Female; Hospital Mortality; Humans; La | 2017 |
Acute kidney injury, plasma lactate concentrations and lactic acidosis in metformin users: A GoDarts study.
Topics: Acidosis, Lactic; Acute Kidney Injury; Aged; Aged, 80 and over; Case-Control Studies; Diabetes Melli | 2017 |
The effects of acute renal denervation on kidney perfusion and metabolism in experimental septic shock.
Topics: Acute Kidney Injury; Animals; Creatinine; Disease Models, Animal; Female; Kidney Cortex; Lactic Acid | 2017 |
High anion gap metabolic acidosis induced by cumulation of ketones, L- and D-lactate, 5-oxoproline and acute renal failure.
Topics: Acid-Base Equilibrium; Acidosis; Acute Kidney Injury; Aged; Female; Humans; Insulin; Ketones; Lactic | 2018 |
Skin perfusion pressure as an indicator of tissue perfusion in valvular heart surgery: Preliminary results from a prospective, observational study.
Topics: Acute Kidney Injury; Aged; Area Under Curve; Cardiopulmonary Bypass; Female; Heart Valve Diseases; H | 2017 |
The Case | Acid-base diagnoses in the 21st century.
Topics: Acidosis; Acute Kidney Injury; Alcoholic Intoxication; Alcoholism; Antidotes; Creatinine; Ethylene G | 2017 |
Allopurinol attenuates acute kidney injury following Bothrops jararaca envenomation.
Topics: Acute Kidney Injury; Allopurinol; Animals; Antioxidants; Bothrops; Crotalid Venoms; Glomerular Filtr | 2017 |
Septic acute kidney injury patients in emergency department: The risk factors and its correlation to serum lactate.
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Biomarkers; Comorbidity; Emergency Service, Hospital; | 2019 |
Serum lactate level accurately predicts mortality in critically ill patients with cirrhosis with acute kidney injury.
Topics: Acute Kidney Injury; Aged; Biomarkers; Critical Illness; Databases, Factual; Female; Hospital Mortal | 2018 |
Involvement of organic cation transporter 2 in the metformin-associated increased lactate levels caused by contrast-induced nephropathy.
Topics: Acidosis, Lactic; Acute Kidney Injury; Animals; Cell Line; Contrast Media; Disease Models, Animal; H | 2018 |
Analysis of the risk factors of acute kidney injury in patients receiving extracorporeal membrane oxygenation
.
Topics: Acute Kidney Injury; Adult; Cardiotonic Agents; Extracorporeal Membrane Oxygenation; Female; Humans; | 2018 |
The role of minocycline in alleviating aluminum phosphide-induced cardiac hemodynamic and renal toxicity.
Topics: Acute Kidney Injury; Aluminum Compounds; Animals; Apoptosis; Blood Pressure; Cytochromes c; Electroc | 2018 |
Acute Kidney Injury in Critically Ill Children Admitted to the PICU for Diabetic Ketoacidosis. A Retrospective Study.
Topics: Acute Kidney Injury; Adolescent; Blood Glucose; Child; Child, Preschool; Critical Illness; Diabetic | 2019 |
Early Postoperative Acute Kidney Injury Among Pediatric Liver Transplant Recipients.
Topics: Acute Kidney Injury; Adolescent; Child; Female; Humans; Lactic Acid; Liver Transplantation; Male; Po | 2021 |
Diglycolic acid inhibits succinate dehydrogenase activity in human proximal tubule cells leading to mitochondrial dysfunction and cell death.
Topics: Acute Kidney Injury; Cells, Cultured; Glycolates; Humans; Kidney Tubules, Proximal; Lactic Acid; Mic | 2013 |
Changes in plasma kynurenic acid concentration in septic shock patients undergoing continuous veno-venous haemofiltration.
Topics: Acute Kidney Injury; Bacterial Infections; Biomarkers; C-Reactive Protein; Calcitonin; Calcitonin Ge | 2014 |
Metformin accumulation: lactic acidosis and high plasmatic metformin levels in a retrospective case series of 66 patients on chronic therapy.
Topics: Acidosis, Lactic; Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Chronic Disease; Creatinine; | 2014 |
Influence of acute kidney injury on short- and long-term outcomes in patients undergoing cardiac surgery: risk factors and prognostic value of a modified RIFLE classification.
Topics: Acute Kidney Injury; Cardiac Surgical Procedures; Cardiovascular Agents; Follow-Up Studies; Hospital | 2013 |
Hemodynamic variables and progression of acute kidney injury in critically ill patients with severe sepsis: data from the prospective observational FINNAKI study.
Topics: Acute Kidney Injury; Blood Pressure; Disease Progression; Dobutamine; Furosemide; Hemodynamics; Huma | 2013 |
Renal cortical pyruvate depletion during AKI.
Topics: Acute Kidney Injury; Adenosine Triphosphate; Animals; Gluconeogenesis; Glucose; Glycogen; Hydrogen P | 2014 |
[Lactic acid as a prognostic marker in obstetric postpartum hemorrhage].
Topics: Acute Kidney Injury; Adult; Biomarkers; Cesarean Section; Disseminated Intravascular Coagulation; Fe | 2014 |
Severe lactic acidosis in critically ill patients with acute kidney injury treated with renal replacement therapy.
Topics: Acidosis, Lactic; Acute Kidney Injury; Adult; Aged; APACHE; Cohort Studies; Critical Care; Critical | 2014 |
Mesenteric lymph drainage alleviates acute kidney injury induced by hemorrhagic shock without resuscitation.
Topics: 2,3-Diphosphoglycerate; Acute Kidney Injury; Animals; Biomarkers; Disease Models, Animal; Drainage; | 2014 |
The utility of scoring systems in critically ill cirrhotic patients admitted to a general intensive care unit.
Topics: Acute Kidney Injury; Adult; Aged; Analysis of Variance; Area Under Curve; Critical Illness; Female; | 2014 |
Normalized lactate load is associated with development of acute kidney injury in patients who underwent cardiopulmonary bypass surgery.
Topics: Acute Kidney Injury; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Case-Control Studies; Fema | 2015 |
[Metformin-induced lactic acidosis : Severe symptoms with difficult diagnostics].
Topics: Acidosis, Lactic; Acute Kidney Injury; Carbon Dioxide; Diabetes Mellitus, Type 2; Epinephrine; Human | 2015 |
Elevated serum uric acid after injury correlates with the early acute kidney in severe burns.
Topics: Acute Kidney Injury; Adult; APACHE; Body Surface Area; Burns; C-Reactive Protein; Cohort Studies; Cr | 2015 |
Predictors of Acute Renal Failure During Extracorporeal Membrane Oxygenation in Pediatric Patients After Cardiac Surgery.
Topics: Acute Kidney Injury; Cardiac Surgical Procedures; Child, Preschool; Extracorporeal Membrane Oxygenat | 2016 |
Plasma neutrophil gelatinase-associated lipocalin as a predictive biomarker for the detection of acute kidney injury in adult poisoning.
Topics: Acute Kidney Injury; Acute-Phase Proteins; Adult; Aged; Biomarkers; Body Mass Index; Creatinine; Fem | 2016 |
Lactic Acidosis in Diabetic Population: Is Metformin Implicated? Results of a Matched Case-Control Study Performed on the Type 2 Diabetes Population of Grenoble Hospital University.
Topics: Acidosis, Lactic; Acute Kidney Injury; Aged; Aged, 80 and over; Biomarkers; Case-Control Studies; Di | 2016 |
[Improvement effect of early goal-directed therapy on the prognosis in patients with septic shock].
Topics: Acute Kidney Injury; Arterial Pressure; Blood Gas Analysis; Central Venous Pressure; Fluid Therapy; | 2015 |
Urinary Strong Ion Difference as a Marker of Renal Dysfunction. A Retrospective Analysis.
Topics: Acute Kidney Injury; Aged; Biomarkers; Calcium; Chlorides; Creatinine; Critical Illness; Female; Hum | 2016 |
Elevated Intraoperative Serum Lactate During Craniotomy Is Associated With New Neurological Deficit and Longer Length of Stay.
Topics: Acute Kidney Injury; Adult; Aged; Cerebrovascular Circulation; Cohort Studies; Craniotomy; Female; H | 2017 |
Elevated Plasma Angiopoietin-2 Levels Are Associated With Fluid Overload, Organ Dysfunction, and Mortality in Human Septic Shock.
Topics: Acute Kidney Injury; Angiopoietin-2; Australia; Biomarkers; Blood Coagulation Disorders; Canada; Coh | 2016 |
Impact of clinical context on acute kidney injury biomarker performances: differences between neutrophil gelatinase-associated lipocalin and L-type fatty acid-binding protein.
Topics: Acute Kidney Injury; Aged; Area Under Curve; Biomarkers; C-Reactive Protein; Critical Illness; Fatty | 2016 |
In situ lactate dehydrogenase activity: a novel renal cortical imaging biomarker of tubular injury?
Topics: Acute Kidney Injury; Alanine; Animals; Bicarbonates; Biomarkers; Carbon Isotopes; Disease Models, An | 2017 |
Lactate clearance is associated with mortality in septic patients with acute kidney injury requiring continuous renal replacement therapy: A cohort study.
Topics: Acute Kidney Injury; Aged; Biomarkers; Brazil; Critical Illness; Female; Follow-Up Studies; Humans; | 2016 |
Ethylene glycol poisoning presenting with a falsely elevated lactate level.
Topics: Acute Kidney Injury; Blood Gas Analysis; Critical Care; Ethylene Glycol; Gas Chromatography-Mass Spe | 2009 |
Albumin dialysis in liver failure: comparison of molecular adsorbent recirculating system and single pass albumin dialysis--a retrospective analysis.
Topics: Acute Kidney Injury; Adult; Aged; Albumins; Bilirubin; Creatinine; Dialysis; Female; gamma-Glutamylt | 2009 |
A case of a rapid drop in lactate.
Topics: Acute Kidney Injury; Adult; Humans; Lactic Acid; Male; Rhabdomyolysis | 2011 |
Toll-like receptor 4 inhibitor TAK-242 attenuates acute kidney injury in endotoxemic sheep.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Cardiac Output; Creatinine; Disease Models, Anima | 2011 |
Antegrade cerebral perfusion with mild hypothermia for aortic arch replacement: single-center experience in 245 consecutive patients.
Topics: Acute Kidney Injury; Aged; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Brain Ischemia; Cardiopulmona | 2011 |
Metformin-associated lactic acidosis following acute kidney injury. Efficacious treatment with continuous renal replacement therapy.
Topics: Acidosis, Lactic; Acute Kidney Injury; Aged; Aged, 80 and over; Biomarkers; Creatinine; Female; Huma | 2012 |
Lactate levels predict mortality and need for peritoneal dialysis in children undergoing congenital heart surgery.
Topics: Acute Kidney Injury; Child, Preschool; Female; Heart Defects, Congenital; Humans; Infant; Intubation | 2012 |
Quantification of systemic delivery of substrates for intermediate metabolism during citrate anticoagulation of continuous renal replacement therapy.
Topics: Acute Kidney Injury; Anticoagulants; Citric Acid; Equipment Design; Glucose; Heparin; Humans; Lactic | 2012 |
Impact of continuous veno-venous hemofiltration on acid-base balance.
Topics: Acid-Base Equilibrium; Acute Kidney Injury; Adult; Aged; Critical Illness; Female; Hemofiltration; H | 2003 |
[Metformin-associated lactic acidosis precipitated by acute renal failure].
Topics: Acidosis, Lactic; Acute Kidney Injury; Aged; Blood Gas Analysis; Diabetes Mellitus, Type 2; Female; | 2003 |
[Metformin-associated lactic acidosis remains a serious complication of metformin therapy].
Topics: Acidosis, Lactic; Acute Kidney Injury; Adult; Aged; Diabetes Complications; Diabetes Mellitus, Type | 2003 |
Strong ion gap.
Topics: Acid-Base Equilibrium; Acute Kidney Injury; Adult; Blood Vessels; Critical Care; Hospital Mortality; | 2005 |
Lactate metabolism in acute uremia.
Topics: Acute Kidney Injury; Adenosine Triphosphate; Energy Metabolism; Glucose; Hemodynamics; Homeostasis; | 2005 |
[A mixed acid-base disorder revealing a cystic dystrophy of aberrant pancreatic tissue].
Topics: Acid-Base Imbalance; Acidosis; Acute Kidney Injury; Adult; Alkalosis; Blood Chemical Analysis; Blood | 2006 |
Early veno-venous haemodiafiltration for sepsis-related multiple organ failure.
Topics: Acid-Base Imbalance; Acute Kidney Injury; Electrolytes; Female; Hemofiltration; Humans; Lactic Acid; | 2005 |
Plasma concentrations of interleukin-6, organ failure, vasopressor support, and successful coronary revascularization in predicting 30-day mortality of patients with cardiogenic shock complicating acute myocardial infarction.
Topics: Acute Kidney Injury; Aged; Biomarkers; Female; Humans; Intensive Care Units; Interleukin-6; Lactic A | 2006 |
Case 7-2006: a man with altered mental status and acute renal failure.
Topics: Acid-Base Equilibrium; Acidosis; Acute Kidney Injury; Diagnosis, Differential; Ethylene Glycol; Huma | 2006 |
Metabolic studies of HgCl2-induced acute renal failure in the rat.
Topics: Acute Kidney Injury; Adenine Nucleotides; Animals; Creatinine; Disease Models, Animal; Dithiothreito | 1981 |
[Effect of adenosine triphosphate-magnesium chloride administration for post-ischemic acute renal failure (I)].
Topics: Acute Kidney Injury; Adenosine Triphosphate; Animals; Disease Models, Animal; Electrolytes; Energy M | 1983 |
Metabolic studies of postischemic acute renal failure in the rat.
Topics: Acute Kidney Injury; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine | 1984 |
Metabolic studies of glycerol-induced acute renal failure in the rat.
Topics: Acute Kidney Injury; Adenine Nucleotides; Animals; Creatinine; Dihydroxyacetone; Disease Models, Ani | 1981 |
Changes in regulators of circulation in patients undergoing continuous pump-driven veno-venous hemofiltration.
Topics: Acute Kidney Injury; Atrial Natriuretic Factor; Blood Circulation; Blood Pressure; Creatinine; Dopam | 1994 |
Acid-base responses to high-volume haemofiltration in the critically ill.
Topics: Acid-Base Imbalance; Acute Kidney Injury; Aged; Aged, 80 and over; Critical Illness; Female; Hemofil | 1993 |
Uptake of glucose during continuous arteriovenous hemofiltration.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Blood Glucose; Blood Urea Nitrogen; | 1993 |
Effect of continuous venovenous hemofiltration with dialysis on lactate clearance in critically ill patients.
Topics: Acidosis, Lactic; Acute Kidney Injury; Adolescent; Adult; Aged; Critical Illness; Dialysis Solutions | 1997 |
Comparison of a lactate-versus acetate-based hemofiltration replacement fluid in patients with acute renal failure.
Topics: Acetates; Acid-Base Equilibrium; Acidosis, Lactic; Acute Kidney Injury; APACHE; Bicarbonates; Blood | 1997 |
Advantages of HCO3 solution with low sodium concentration over standard lactate solutions for acute peritoneal dialysis.
Topics: Acute Kidney Injury; Bicarbonates; Blood Urea Nitrogen; Child; Child, Preschool; Creatinine; Dialysi | 1997 |
Which organic acids does hemofiltrate contain in the presence of acute renal failure?
Topics: Acetoacetates; Acids; Acute Kidney Injury; Adult; APACHE; Child; Chromatography, Gas; Critical Illne | 1999 |
Splanchnic metabolism of fuel substrates in acute liver failure.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acute Kidney Injury; Adult; Blood Glucose; Female; Hepatic Enc | 2000 |
Noninvasive monitoring of citrate, acetate, lactate, and renal medullary osmolyte excretion in urine as biomarkers of exposure to ischemic reperfusion injury.
Topics: Acetic Acid; Acetylglucosaminidase; Acute Kidney Injury; Adenosine; Allopurinol; Animals; Biomarkers | 2000 |
Abuse of germanium associated with fatal lactic acidosis.
Topics: Acidosis; Acute Kidney Injury; Adult; Chemical and Drug Induced Liver Injury; Female; Germanium; Hum | 1992 |
Renal cortical intermediary metabolism in the recovery phase of postischemic acute renal failure in the dog.
Topics: Acute Kidney Injury; Adenosine Triphosphate; Animals; Dogs; Glomerular Filtration Rate; Ischemia; Ki | 1992 |
Fat elimination in acute renal failure: long-chain vs medium-chain triglycerides.
Topics: Acute Kidney Injury; Adult; Blood Glucose; Drug Combinations; Fat Emulsions, Intravenous; Fats; Fatt | 1992 |
Hyperlactataemia and metabolic acidosis during haemofiltration using lactate-buffered fluids.
Topics: Acidosis, Lactic; Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Buffers; Female; Hemofiltrati | 1991 |
[Acute renal failure in patients with multiple organ failure].
Topics: Acute Kidney Injury; Hemofiltration; Humans; Ketone Bodies; Lactates; Lactic Acid; Multiple Organ Fa | 1991 |
[Bicarbonate instead of lactate buffered substitution solution for continuous hemofiltration in intensive care].
Topics: Acid-Base Equilibrium; Acute Kidney Injury; Adult; Aged; Bicarbonates; Critical Care; Electrolytes; | 1990 |
Organic acids in ethylene glycol intoxication.
Topics: Acidosis; Acute Kidney Injury; Adult; Carboxylic Acids; Ethanol; Ethylene Glycol; Ethylene Glycols; | 1986 |