lactic acid has been researched along with Acquired Metabolic Diseases, Brain in 40 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "D-Lactic acidosis is an unique complication of jejunoileal bypass occurring because of alteration of colonic bacterial flora with selective proliferation of D-lactate-producing bacteria." | 7.69 | D-lactic acidosis in a patient with jejunoileal bypass. ( Kadakia, SC, 1995) |
| "D-Lactic acidosis associated with encephalopathy is a clinical condition that occurs in patients with short bowel syndrome." | 7.69 | Abnormal fecal flora in a patient with short bowel syndrome. An in vitro study on effect of pH on D-lactic acid production. ( Ascione, A; Bustos, D; Caldarini, MI; D'Agostino, D; DePaula, JA; Greco, G; Negri, G; Pons, S, 1996) |
| "An enzymatic study of cultured skin fibroblasts was made in 28 patients with lactic acidosis." | 7.67 | Biochemical study in 28 children with lactic acidosis, in relation to Leigh's encephalomyelopathy. ( Iinuma, K; Ito, T; Miyabayashi, S; Narisawa, K; Tada, K, 1985) |
| "Profound and prolonged hypoglycemia, normal or higher body temperature, and a low lactic acid level during hypoglycemia may be predictors of a poor outcome in patients with hypoglycemic encephalopathy." | 3.79 | Predictors of outcome in hypoglycemic encephalopathy. ( Fujita, N; Igarashi, S; Ikeda, T; Kanazawa, M; Kuwabara, T; Nishizawa, M; Sato, A; Shimohata, T; Takahashi, T; Tanaka, H, 2013) |
| "D-Lactic acidosis is an unique complication of jejunoileal bypass occurring because of alteration of colonic bacterial flora with selective proliferation of D-lactate-producing bacteria." | 3.69 | D-lactic acidosis in a patient with jejunoileal bypass. ( Kadakia, SC, 1995) |
| "D-Lactic acidosis associated with encephalopathy is a clinical condition that occurs in patients with short bowel syndrome." | 3.69 | Abnormal fecal flora in a patient with short bowel syndrome. An in vitro study on effect of pH on D-lactic acid production. ( Ascione, A; Bustos, D; Caldarini, MI; D'Agostino, D; DePaula, JA; Greco, G; Negri, G; Pons, S, 1996) |
| "An enzymatic study of cultured skin fibroblasts was made in 28 patients with lactic acidosis." | 3.67 | Biochemical study in 28 children with lactic acidosis, in relation to Leigh's encephalomyelopathy. ( Iinuma, K; Ito, T; Miyabayashi, S; Narisawa, K; Tada, K, 1985) |
| "In a population based cohort study 134 type 2 diabetes patients were examined at baseline and 3-year follow-up." | 2.75 | Low plasma lactate concentration as a biomarker of an incompetent brain-pull: a risk factor for weight gain in type 2 diabetes patients. ( Hitze, B; Hubold, C; Lehnert, H; Marxsen, A; Meier, S; Oltmanns, KM; Pellerin, L; Peters, A; Schweiger, U; van Dyken, R, 2010) |
| "The disorders causing myoclonus have been compared to those in which myoclonus has been reported." | 2.37 | Myoclonus and mitochondrial myopathy. ( Hopkins, LC; Rosing, HS, 1986) |
| "Some children with mitochondrial disorders manifest only mild or intermittent elevation of lactate levels." | 1.37 | Elevated CSF-lactate is a reliable marker of mitochondrial disorders in children even after brief seizures. ( Honzík, T; Ješina, P; Magner, M; Svandová, I; Szentiványi, K; Tesařová, M; Zeman, J, 2011) |
| "Biotinidase deficiency is a metabolic disorder characterized by inability to recycle biotin with resultant delayed myelination." | 1.35 | Biotinidase deficiency: a reversible metabolic encephalopathy. Neuroimaging and MR spectroscopic findings in a series of four patients. ( Desai, S; Ganesan, K; Hegde, A, 2008) |
| "Both patients had PDH deficiency caused by a new mutation (G585C) in the PDHA1 gene, which is predicted to replace a highly conserved glycine at codon 195 by alanine." | 1.35 | Pyruvate dehydrogenase deficiency presenting as intermittent isolated acute ataxia. ( Debray, FG; Gagne, R; Laframboise, R; Lambert, M; MacKay, N; Maranda, B; Mitchell, GA; Robinson, BH, 2008) |
| "Glutaric acidemia type I is an inherited metabolic disorder caused by a severe deficiency of the mitochondrial glutaryl-CoA dehydrogenase activity leading to accumulation of predominantly glutaric and 3-hydroxyglutaric acids in the brain tissue of the affected patients." | 1.34 | Evidence for a synergistic action of glutaric and 3-hydroxyglutaric acids disturbing rat brain energy metabolism. ( Ceolato, PC; Dutra-Filho, CS; Ferreira, GC; Latini, A; Perry, ML; Schuck, PF; Tonin, A; Vargas, CR; Viegas, CM; Wajner, M; Wannmacher, CM; Wyse, AT, 2007) |
| "After subarachnoid hemorrhage (SAH) cerebral metabolism is significantly impaired." | 1.34 | Cerebral energy failure after subarachnoid hemorrhage: the role of relative hyperglycolysis. ( Böker, DK; Oertel, MF; Scharbrodt, W; Schmidinger, A; Schwedler, M; Stein, M; Wachter, D, 2007) |
| "Aicardi-Goutières syndrome is a rare progressive encephalopathy characterized by acquired microcephaly, basal ganglia calcification, and chronic CSF lymphocytosis, raised levels of interferon alpha in CSF and plasma and chill-blain type lesions." | 1.32 | Brain lactic alkalosis in Aicardi-Goutières syndrome. ( Battini, R; Bianchi, MC; Cheong, J; Cioni, G; Cowan, FM; Cox, IJ; Robertson, NJ; Stafler, P; Tosetti, M, 2004) |
| "Recurrent episodes of confusion are most commonly due to transient brain dysfunction related to vascular, epileptic or metabolic abnormalities." | 1.31 | [Recurrent encephalopathy after small bowel resection. Implication of D-lactate]. ( Burkhard, PR; Hadengue, A; Lalive, PH; Mensi, N, 2001) |
| "The majority of patients with PDHC deficiency have abnormalities in the major catalytic and regulatory subunit, E1 alpha, which is encoded on the X chromosome." | 1.29 | Cerebral dysgenesis and lactic acidemia: an MRI/MRS phenotype associated with pyruvate dehydrogenase deficiency. ( Arnold, DL; Brown, GK; Brown, RM; Legris, M; Matthews, PM; Otero, LJ; Scriver, CR; Shevell, MI, 1994) |
| "Despite regional variability of demyelination, proton magnetic resonance spectroscopy revealed a specific metabolic pattern in all patients, with only moderate reduction of N-acetylaspartate, normal or reduced choline-containing compounds, normal or enhanced myo-inositol and no detectable lactate, which differs from findings in progressive cerebral adrenoleukodystrophy which usually exhibits a severe reduction of N-acetylaspartate and marked increases of choline-containing compounds, myo-inositol, and lactate." | 1.29 | Arrested cerebral adrenoleukodystrophy: a clinical and proton magnetic resonance spectroscopy study in three patients. ( Frahm, J; Hanefeld, F; Hunneman, DH; Jost, W; Korenke, GC; Krasemann, E; Pouwels, PJ; Stoeckler, S, 1996) |
| "The CT scan showed multiple intracerebral infarcts, basal ganglia calcifications, and cerebral atrophy." | 1.28 | [Mitochondrial encephalomyopathy. Report of a case]. ( Chen, Q, 1990) |
| "We studied a 17-year-old girl with subacute necrotizing encephalomyelopathy (Leigh syndrome)." | 1.27 | Subacute necrotizing encephalomyelopathy (Leigh syndrome) associated with disturbed oxidation of pyruvate, malate and 2-oxoglutarate in muscle and liver. ( Den Hartog, MR; Fischer, JC; Gabreëls, FJ; Janssen, AJ; Renier, WO; Ruitenbeek, W; Slooff, JL; Trijbels, JM; Van Erven, PM, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (22.50) | 18.7374 |
| 1990's | 11 (27.50) | 18.2507 |
| 2000's | 12 (30.00) | 29.6817 |
| 2010's | 8 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ikeda, T | 1 |
| Takahashi, T | 1 |
| Sato, A | 1 |
| Tanaka, H | 1 |
| Igarashi, S | 1 |
| Fujita, N | 1 |
| Kuwabara, T | 1 |
| Kanazawa, M | 1 |
| Nishizawa, M | 1 |
| Shimohata, T | 1 |
| Amaral, AU | 1 |
| Cecatto, C | 1 |
| Seminotti, B | 1 |
| Ribeiro, CA | 1 |
| Lagranha, VL | 1 |
| Pereira, CC | 1 |
| de Oliveira, FH | 1 |
| de Souza, DG | 1 |
| Goodman, S | 1 |
| Woontner, M | 1 |
| Wajner, M | 2 |
| Liguori, C | 1 |
| Chiaravalloti, A | 1 |
| Sancesario, G | 1 |
| Stefani, A | 1 |
| Sancesario, GM | 1 |
| Mercuri, NB | 1 |
| Schillaci, O | 1 |
| Pierantozzi, M | 1 |
| Desai, S | 1 |
| Ganesan, K | 1 |
| Hegde, A | 1 |
| Tachikawa, M | 1 |
| Hosoya, K | 1 |
| Ohtsuki, S | 1 |
| Terasaki, T | 1 |
| Liddell, JR | 1 |
| Zwingmann, C | 2 |
| Schmidt, MM | 1 |
| Thiessen, A | 1 |
| Leibfritz, D | 1 |
| Robinson, SR | 1 |
| Dringen, R | 1 |
| van Dyken, R | 1 |
| Hubold, C | 1 |
| Meier, S | 1 |
| Hitze, B | 1 |
| Marxsen, A | 1 |
| Oltmanns, KM | 1 |
| Schweiger, U | 1 |
| Lehnert, H | 1 |
| Pellerin, L | 1 |
| Peters, A | 1 |
| Girard, N | 1 |
| Magner, M | 1 |
| Szentiványi, K | 1 |
| Svandová, I | 1 |
| Ješina, P | 1 |
| Tesařová, M | 1 |
| Honzík, T | 1 |
| Zeman, J | 1 |
| Stein, NR | 1 |
| McArthur, DL | 1 |
| Etchepare, M | 1 |
| Vespa, PM | 1 |
| Mayeur, C | 1 |
| Gratadoux, JJ | 1 |
| Bridonneau, C | 1 |
| Chegdani, F | 1 |
| Larroque, B | 1 |
| Kapel, N | 1 |
| Corcos, O | 1 |
| Thomas, M | 1 |
| Joly, F | 1 |
| Robertson, NJ | 1 |
| Stafler, P | 1 |
| Battini, R | 1 |
| Cheong, J | 1 |
| Tosetti, M | 1 |
| Bianchi, MC | 1 |
| Cox, IJ | 1 |
| Cowan, FM | 1 |
| Cioni, G | 1 |
| Shiihara, T | 1 |
| Kato, M | 1 |
| Hayasaka, K | 1 |
| Alexander, JJ | 1 |
| Quigg, R | 1 |
| Alves, OL | 1 |
| Bullock, R | 1 |
| Clausen, T | 1 |
| Reinert, M | 1 |
| Reeves, TM | 1 |
| Ferreira, GC | 1 |
| Tonin, A | 1 |
| Schuck, PF | 1 |
| Viegas, CM | 1 |
| Ceolato, PC | 1 |
| Latini, A | 1 |
| Perry, ML | 1 |
| Wyse, AT | 1 |
| Dutra-Filho, CS | 1 |
| Wannmacher, CM | 1 |
| Vargas, CR | 1 |
| Oertel, MF | 1 |
| Schwedler, M | 1 |
| Stein, M | 1 |
| Wachter, D | 1 |
| Scharbrodt, W | 1 |
| Schmidinger, A | 1 |
| Böker, DK | 1 |
| Halim, ND | 1 |
| Lipska, BK | 1 |
| Hyde, TM | 1 |
| Deep-Soboslay, A | 1 |
| Saylor, EM | 1 |
| Herman, MM | 1 |
| Thakar, J | 1 |
| Verma, A | 1 |
| Kleinman, JE | 1 |
| Debray, FG | 1 |
| Lambert, M | 1 |
| Gagne, R | 1 |
| Maranda, B | 1 |
| Laframboise, R | 1 |
| MacKay, N | 1 |
| Robinson, BH | 1 |
| Mitchell, GA | 1 |
| Narisawa, K | 2 |
| Miyabayashi, S | 2 |
| Tada, K | 2 |
| Kadakia, SC | 1 |
| Shevell, MI | 1 |
| Matthews, PM | 1 |
| Scriver, CR | 1 |
| Brown, RM | 1 |
| Otero, LJ | 1 |
| Legris, M | 1 |
| Brown, GK | 1 |
| Arnold, DL | 1 |
| Hanefeld, F | 3 |
| Holzbach, U | 1 |
| Kruse, B | 1 |
| Wilichowski, E | 1 |
| Christen, HJ | 2 |
| Frahm, J | 3 |
| Gurevitch, J | 1 |
| Sela, B | 1 |
| Jonas, A | 1 |
| Golan, H | 1 |
| Yahav, Y | 1 |
| Passwell, JH | 1 |
| Caldarini, MI | 1 |
| Pons, S | 1 |
| D'Agostino, D | 1 |
| DePaula, JA | 1 |
| Greco, G | 1 |
| Negri, G | 1 |
| Ascione, A | 1 |
| Bustos, D | 1 |
| Korenke, GC | 1 |
| Pouwels, PJ | 2 |
| Hunneman, DH | 1 |
| Stoeckler, S | 1 |
| Krasemann, E | 1 |
| Jost, W | 1 |
| Brockmann, K | 1 |
| Cady, EB | 1 |
| Amess, P | 1 |
| Penrice, J | 1 |
| Wylezinska, M | 1 |
| Sams, V | 1 |
| Wyatt, JS | 1 |
| Kugel, H | 1 |
| Heindel, W | 1 |
| Roth, B | 1 |
| Ernst, S | 1 |
| Lackner, K | 1 |
| Lalive, PH | 1 |
| Hadengue, A | 1 |
| Mensi, N | 1 |
| Burkhard, PR | 1 |
| Marks, HG | 1 |
| Caro, PA | 1 |
| Wang, ZY | 1 |
| Detre, JA | 1 |
| Bogdan, AR | 1 |
| Gusnard, DA | 1 |
| Zimmerman, RA | 1 |
| Chen, Q | 1 |
| Ogier, H | 1 |
| Lombes, A | 1 |
| Scholte, HR | 1 |
| Poll-The, BT | 1 |
| Fardeau, M | 1 |
| Alcardi, J | 1 |
| Vignes, B | 1 |
| Niaudet, P | 1 |
| Saudubray, JM | 1 |
| Harigaya, Y | 1 |
| Shoji, M | 1 |
| Okamoto, K | 1 |
| Hirai, S | 1 |
| Sato, T | 1 |
| Ito, T | 1 |
| Iinuma, K | 1 |
| Hopkins, LC | 1 |
| Rosing, HS | 1 |
| Ohama, E | 1 |
| Ikuta, F | 1 |
| Nakamura, N | 1 |
| Siemes, H | 1 |
| Van Erven, PM | 1 |
| Gabreëls, FJ | 1 |
| Ruitenbeek, W | 1 |
| Den Hartog, MR | 1 |
| Fischer, JC | 1 |
| Renier, WO | 1 |
| Trijbels, JM | 1 |
| Slooff, JL | 1 |
| Janssen, AJ | 1 |
| Kluitmann, G | 1 |
| Braumann, HG | 1 |
| Kratz, HW | 1 |
| Liersch, R | 1 |
| Langes, K | 1 |
| Seitz, RJ | 1 |
| Frenzel, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Multi-center Clinical Research About Standard Diagnosis and Treatment of Neonate Severe Digestive System Malformation[NCT02699320] | 33 participants (Actual) | Observational | 2015-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for lactic acid and Acquired Metabolic Diseases, Brain
| Article | Year |
|---|---|
A novel relationship between creatine transport at the blood-brain and blood-retinal barriers, creatine biosynthesis, and its use for brain and retinal energy homeostasis.
Topics: Animals; Biological Transport; Blood-Brain Barrier; Blood-Retinal Barrier; Brain Diseases, Metabolic | 2007 |
[Magnetic resonance spectroscopy for cerebral imaging].
Topics: Apoptosis; Aspartic Acid; Asphyxia Neonatorum; Biomarkers, Tumor; Brain; Brain Diseases; Brain Disea | 2010 |
Myoclonus and mitochondrial myopathy.
Topics: Adolescent; Brain Diseases, Metabolic; Central Nervous System Diseases; Electroencephalography; Epil | 1986 |
Mitochondrial abnormalities in choroid plexus of Leigh disease.
Topics: Brain Diseases, Metabolic; Child; Child, Preschool; Choroid Plexus; Female; Humans; Infant; Lactates | 1988 |
1 trial available for lactic acid and Acquired Metabolic Diseases, Brain
| Article | Year |
|---|---|
Low plasma lactate concentration as a biomarker of an incompetent brain-pull: a risk factor for weight gain in type 2 diabetes patients.
Topics: Adult; Biomarkers; Brain Diseases, Metabolic; Cohort Studies; Diabetes Mellitus, Type 2; Energy Meta | 2010 |
35 other studies available for lactic acid and Acquired Metabolic Diseases, Brain
| Article | Year |
|---|---|
Predictors of outcome in hypoglycemic encephalopathy.
Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Body Temperature; Brain Diseases, Metabolic; Female; | 2013 |
Experimental evidence that bioenergetics disruption is not mainly involved in the brain injury of glutaryl-CoA dehydrogenase deficient mice submitted to lysine overload.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases; Brain Diseases, Metabolic; Cerebral C | 2015 |
Cerebrospinal fluid lactate levels and brain [18F]FDG PET hypometabolism within the default mode network in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Brain; Brain Diseases, Metabolic; Fluorodeoxyglucose F18; Glucose; Humans; | 2016 |
Biotinidase deficiency: a reversible metabolic encephalopathy. Neuroimaging and MR spectroscopic findings in a series of four patients.
Topics: Biomarkers; Biotinidase Deficiency; Brain; Brain Diseases, Metabolic; Female; Humans; Infant; Lactic | 2008 |
Sustained hydrogen peroxide stress decreases lactate production by cultured astrocytes.
Topics: Animals; Astrocytes; Brain; Brain Diseases, Metabolic; Cells, Cultured; Energy Metabolism; Glucose; | 2009 |
Elevated CSF-lactate is a reliable marker of mitochondrial disorders in children even after brief seizures.
Topics: Adolescent; Biomarkers; Brain Diseases, Metabolic; Child, Preschool; Epilepsy; Female; Humans; Infan | 2011 |
Early cerebral metabolic crisis after TBI influences outcome despite adequate hemodynamic resuscitation.
Topics: Adult; Blood Pressure; Brain; Brain Diseases, Metabolic; Brain Injuries; Cardiopulmonary Resuscitati | 2012 |
Faecal D/L lactate ratio is a metabolic signature of microbiota imbalance in patients with short bowel syndrome.
Topics: Adult; Aged; Bacteroides; Bicarbonates; Brain Diseases, Metabolic; Clostridium; Feces; Female; Human | 2013 |
Brain lactic alkalosis in Aicardi-Goutières syndrome.
Topics: Alkalosis; Aspartic Acid; Basal Ganglia; Brain; Brain Diseases, Metabolic; Calcinosis; Creatinine; E | 2004 |
Clinically mild encephalitis/encephalopathy with a reversible splenial lesion.
Topics: Adolescent; Brain Diseases, Metabolic; Corpus Callosum; Diagnosis, Differential; DNA, Mitochondrial; | 2005 |
MRL/lpr mice have alterations in brain metabolism as shown with [1H-13C] NMR spectroscopy.
Topics: Alanine; Amino Acids; Animals; Brain; Brain Diseases, Metabolic; Brain Edema; Carbon Radioisotopes; | 2005 |
Concurrent monitoring of cerebral electrophysiology and metabolism after traumatic brain injury: an experimental and clinical study.
Topics: Action Potentials; Adult; Animals; Brain Diseases, Metabolic; Brain Injuries; Cerebral Cortex; Disea | 2005 |
Evidence for a synergistic action of glutaric and 3-hydroxyglutaric acids disturbing rat brain energy metabolism.
Topics: Animals; Antioxidants; Brain; Brain Chemistry; Brain Diseases, Metabolic; Creatine Kinase; Drug Syne | 2007 |
Cerebral energy failure after subarachnoid hemorrhage: the role of relative hyperglycolysis.
Topics: Adult; Blood Pressure; Brain Diseases, Metabolic; Brain Ischemia; Cerebral Arteries; Cerebrovascular | 2007 |
Increased lactate levels and reduced pH in postmortem brains of schizophrenics: medication confounds.
Topics: Animals; Antipsychotic Agents; Artifacts; Brain; Brain Chemistry; Brain Diseases, Metabolic; Cerebel | 2008 |
Pyruvate dehydrogenase deficiency presenting as intermittent isolated acute ataxia.
Topics: Ataxia; Basal Ganglia Diseases; Binding Sites; Brain Diseases, Metabolic; Child; Child, Preschool; D | 2008 |
[Congenital lactic acidemia].
Topics: Acidosis; Brain Diseases, Metabolic; Child; Cytochrome-c Oxidase Deficiency; Humans; Infant; Lactate | 1983 |
D-lactic acidosis in a patient with jejunoileal bypass.
Topics: Acidosis, Lactic; Brain Diseases, Metabolic; Colon; Female; Humans; Jejunoileal Bypass; Lactates; La | 1995 |
Cerebral dysgenesis and lactic acidemia: an MRI/MRS phenotype associated with pyruvate dehydrogenase deficiency.
Topics: Acidosis, Lactic; Agenesis of Corpus Callosum; Brain; Brain Damage, Chronic; Brain Diseases, Metabol | 1994 |
Diffuse white matter disease in three children: an encephalopathy with unique features on magnetic resonance imaging and proton magnetic resonance spectroscopy.
Topics: Aspartic Acid; Blood Glucose; Brain; Brain Diseases, Metabolic; Child; Child, Preschool; Choline; Ch | 1993 |
D-lactic acidosis: a treatable encephalopathy in pediatric patients.
Topics: Acidosis, Lactic; Brain Diseases, Metabolic; Enteral Nutrition; Humans; Infant; Lactates; Lactic Aci | 1993 |
Abnormal fecal flora in a patient with short bowel syndrome. An in vitro study on effect of pH on D-lactic acid production.
Topics: Bacteria, Anaerobic; Brain Diseases, Metabolic; Child; Fatty Acids, Volatile; Feces; Humans; Hydroge | 1996 |
Arrested cerebral adrenoleukodystrophy: a clinical and proton magnetic resonance spectroscopy study in three patients.
Topics: Aspartic Acid; Brain; Brain Diseases, Metabolic; Child; Choline; Demyelinating Diseases; Female; Hum | 1996 |
Localized proton magnetic resonance spectroscopy of cerebral metabolic disturbances in children with neuronal ceroid lipofuscinosis.
Topics: Aspartic Acid; Brain; Brain Diseases, Metabolic; Brain Mapping; Child; Child, Preschool; Choline; Cr | 1996 |
Early cerebral-metabolite quantification in perinatal hypoxic-ischaemic encephalopathy by proton and phosphorus magnetic resonance spectroscopy.
Topics: Adenosine Triphosphate; Aspartic Acid; Brain Diseases, Metabolic; Brain Ischemia; Humans; Infant, Ne | 1997 |
Proton MR spectroscopy in infants with cerebral energy deficiency due to hypoxia and metabolic disorders.
Topics: Aspartic Acid; Basal Ganglia; Brain; Brain Diseases, Metabolic; Child, Preschool; Follow-Up Studies; | 1998 |
[Recurrent encephalopathy after small bowel resection. Implication of D-lactate].
Topics: Acidosis, Lactic; Brain Diseases, Metabolic; Confusion; Humans; Intestine, Small; Ischemia; Lactic A | 2001 |
Use of computed tomography, magnetic resonance imaging, and localized 1H magnetic resonance spectroscopy in Canavan's disease: a case report.
Topics: Amidohydrolases; Amino Acid Metabolism, Inborn Errors; Aspartic Acid; Brain Diseases, Metabolic; Chi | 1991 |
[Mitochondrial encephalomyopathy. Report of a case].
Topics: Adult; Brain Diseases, Metabolic; Cerebral Infarction; Humans; Lactates; Lactic Acid; Male; Mitochon | 1990 |
de Toni-Fanconi-Debré syndrome with Leigh syndrome revealing severe muscle cytochrome c oxidase deficiency.
Topics: Brain Diseases, Metabolic; Child, Preschool; Cytochrome-c Oxidase Deficiency; Fanconi Syndrome; Fema | 1988 |
[A case of mitochondrial encephalomyopathy with myoclonic attacks, hyper-lactic-pyruvic acidemia, and decreased activities of complex II and cytochrome c oxidase].
Topics: Adult; Brain Diseases, Metabolic; Electron Transport Complex II; Electron Transport Complex IV; Huma | 1988 |
Biochemical study in 28 children with lactic acidosis, in relation to Leigh's encephalomyelopathy.
Topics: Acidosis; Adolescent; Brain Diseases, Metabolic; Carboxy-Lyases; Cells, Cultured; Child; Child, Pres | 1985 |
[Mitochondrial myopathies and encephalomyopathies. Neuromuscular and central nervous system diseases caused by defects in mitochondrial oxidative metabolism].
Topics: Brain; Brain Diseases, Metabolic; Carnitine O-Acetyltransferase; Child; Citric Acid Cycle; Cytochrom | 1985 |
Subacute necrotizing encephalomyelopathy (Leigh syndrome) associated with disturbed oxidation of pyruvate, malate and 2-oxoglutarate in muscle and liver.
Topics: Adolescent; Brain; Brain Diseases, Metabolic; Enzymes; Female; Humans; Ketoglutaric Acids; Lactates; | 1985 |
[Acute course of Leigh syndrome with hypertrophic cardiomyopathy in a female infant].
Topics: Acidosis; Amino Acids; Brain Diseases, Metabolic; Cardiac Tamponade; Cardiomyopathy, Hypertrophic; D | 1985 |