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lactic acid and Acidosis, Respiratory

lactic acid has been researched along with Acidosis, Respiratory in 30 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Acidosis, Respiratory: Respiratory retention of carbon dioxide. It may be chronic or acute.

Research Excerpts

ExcerptRelevanceReference
" Initial severe acidosis consisted of acute respiratory acidosis from ventilation-perfusion mismatch and acute metabolic acidosis resulting from bronchospasm and hypoxia-related lactic acidosis, respectively."8.02Salbutamol-induced lactic acidosis in status asthmaticus survivor. ( Boonkaya, S; Phoophiboon, V; Singhagowinta, P; Sriprasart, T, 2021)
" Initial severe acidosis consisted of acute respiratory acidosis from ventilation-perfusion mismatch and acute metabolic acidosis resulting from bronchospasm and hypoxia-related lactic acidosis, respectively."4.02Salbutamol-induced lactic acidosis in status asthmaticus survivor. ( Boonkaya, S; Phoophiboon, V; Singhagowinta, P; Sriprasart, T, 2021)
"The present study was designed to determine whether lactate changes the critical pH point at which the recovery of rat population spike is inhibited following glucose-oxygen deprivation and second, which degree of lactic acidosis is similar to the effect of CO2 acidosis."3.69Effect of lactic and CO2 acidosis on neuronal function following glucose-oxygen deprivation in rat hippocampal slices. ( Kemmotsu, O; Morimoto, Y, 1994)
"With the same degree of lactic acidosis (blood lactate concentration of 52 mmol/L), the position of the oxyhemoglobin dissociation curve was the same for blood with PCO2 of 30 torr (4 kPa) and pH of 6."3.69Effect of extreme metabolic acidosis on oxygen delivery capacity of the blood--an in vitro investigation of changes in the oxyhemoglobin dissociation curve in blood with pH values of approximately 6.30. ( Leraand, S; Opdahl, H; Refsum, HE, 1997)
"Respiratory acidosis is associated to high concentrations of S100B protein in umbilical cord blood at birth."1.51Neuroapoptosis in newborns with respiratory acidosis at birth. ( Cañavate-Solano, C; Cuadros-Muñoz, JF; Fernández-Alba, JJ; González-Macías, C; Mayor-Reyes, M; Mesa-Suárez, P; Pérez-Ramos, S; Quintero-Prado, R; Ramos-Ramos, V; Santotoribio, JD; Soto-Pazos, E; Vilar-Sanchez, Á, 2019)
"The partial metabolic compensation for respiratory acidosis produced by ≤ 10% CO2 exposures occurred in proportion to CO2 concentrations in both strains, but metabolic compensation for 20% CO2 respiratory acidosis was depressed at 2, 6 and 24h, particularly in broiler embryos."1.42Hypercapnic thresholds for embryonic acid-base metabolic compensation and hematological regulation during CO2 challenges in layer and broiler chicken strains. ( Burggren, WW; Mueller, CA; Tazawa, H, 2015)
"While respiratory alkalosis occurred in patients with better preservation of FEV1, respiratory acidosis was observed with more severe airway obstruction, as was increased lactate in the majority of patients, independent of PaO(2) and PaCO(2) levels."1.39Acid-base patterns in acute severe asthma. ( Adrogué, HJ; Gonzalez, S; Menga, G; Raimondi, GA; Zaltsman, J, 2013)
"Hypercapnic Chronic Obstructive Pulmonary Disease (COPD) exacerbation in patients with comorbidities and multidrug therapy is complicated by mixed acid-base, hydro-electrolyte and lactate disorders."1.38Mixed acid-base disorders, hydroelectrolyte imbalance and lactate production in hypercapnic respiratory failure: the role of noninvasive ventilation. ( Conti, V; Di Nicola, M; Di Stefano, F; Paone, G; Petroianni, A; Ricci, A; Terzano, C, 2012)
"During acute respiratory acidosis at rest, the eventual change in muscle pH was consistent with passive buffering and was unaffected by amiloride or DIDS, implying no significant contribution of proton fluxes."1.29pH control in rat skeletal muscle during exercise, recovery from exercise, and acute respiratory acidosis. ( Kemp, GJ; Radda, GK; Sanderson, AL; Thompson, CH, 1994)
"During acute respiratory acidosis increments in cisternal cerebrospinal fluid (CSF) [HCO3-] approximate decrements in CSF [Cl-] with CSF [Na+] remaining unchanged; the mechanisms mediating this reciprocal anionic relationship are unclear."1.27Effects of 'DIDS', an anion transport blocker, on CSF [HCO3-] in respiratory acidosis. ( Javaheri, S; Weyne, J, 1984)
"During respiratory acidosis, this value was 0."1.27Role of acidosis in early contractile dysfunction during ischemia: evidence from pHo measurements. ( Couper, GS; Hiltbrand, B; Shine, KI; Weiss, J, 1984)
"The effects of respiratory acidosis on glycolysis in the autoperfused canine gastrocnemius-plantaris were studied using anesthetized dogs that were ventilated either with air (n = 30) or with 4% CO2-21% O2-75% N2 (n = 30)."1.27Skeletal muscle lactate release and glycolytic intermediates during hypercapnia. ( Barclay, JK; Graham, TE; Wilson, BA, 1986)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199010 (33.33)18.7374
1990's9 (30.00)18.2507
2000's4 (13.33)29.6817
2010's6 (20.00)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Santotoribio, JD1
Cañavate-Solano, C1
Quintero-Prado, R1
González-Macías, C1
Soto-Pazos, E1
Vilar-Sanchez, Á1
Mesa-Suárez, P1
Ramos-Ramos, V1
Cuadros-Muñoz, JF1
Mayor-Reyes, M1
Pérez-Ramos, S1
Fernández-Alba, JJ1
Phoophiboon, V1
Singhagowinta, P1
Boonkaya, S1
Sriprasart, T1
Raimondi, GA1
Gonzalez, S1
Zaltsman, J1
Menga, G1
Adrogué, HJ1
Burggren, WW1
Mueller, CA1
Tazawa, H1
Shartau, RB1
Baker, DW1
Brauner, CJ1
Ostergaard, L1
Kjaer, K1
Jensen, K1
Gladden, LB1
Martinussen, T1
Pedersen, PK1
Terzano, C1
Di Stefano, F1
Conti, V1
Di Nicola, M1
Paone, G1
Petroianni, A1
Ricci, A1
KATZMAN, R1
VILLEE, CA1
BEECHER, HK1
Bassuk, AG1
Joshi, A1
Burton, BK1
Larsen, MB1
Burrowes, DM1
Stack, C1
Piccioni, MA1
Leirner, AA1
Auler, JO1
Davis, EC1
Jackson, DC1
Javaheri, S1
Weyne, J1
Nattie, EE1
Edwards, WH1
Marin-Padilla, M1
Craan, AG1
Vinay, P1
Lemieux, G1
Gougoux, A1
Weiss, J1
Couper, GS1
Hiltbrand, B1
Shine, KI1
Lebedeva, VA1
Filippova, LV1
Bratus', TN1
Iartsev, VN1
Pass, LJ1
Schloerb, PR1
Chow, FT1
Graham, M1
Pearce, FJ1
Franklin, MW1
Drucker, WR1
Morimoto, Y2
Kemmotsu, O1
Kemp, GJ1
Thompson, CH1
Sanderson, AL1
Radda, GK1
Kette, F1
Weil, MH1
Gazmuri, RJ1
Bisera, J1
Rackow, EC1
Refsum, HE1
Opdahl, H1
Leraand, S1
Heino, A1
Hartikainen, J1
Merasto, ME1
Alhava, E1
Takala, J1
Kubonoya, K1
Yoneyama, Y1
Sawa, R1
Araki, T1
Power, GG1
Polkey, MI1
Hawkins, P1
Kyroussis, D1
Ellum, SG1
Sherwood, R1
Moxham, J1
Orr, JA1
Carrithers, JA1
Liu, F1
Shirer, HW1
McLellan, TM1
Corbett, RJ1
Laptook, AR1
Graham, TE1
Barclay, JK1
Wilson, BA1
Spriet, LL1
Matsos, CG1
Peters, SJ1
Heigenhauser, GJ1
Jones, NL1
Sadchikov, DV1
Kutyreva, NV1
Lugovskaia, TB1

Reviews

1 review available for lactic acid and Acidosis, Respiratory

ArticleYear
[Tissue chemoreceptors].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1982, Volume: 68, Issue:2

    Topics: Acid-Base Imbalance; Acidosis; Acidosis, Respiratory; Animals; Bicarbonates; Blood Pressure; Carbon

1982

Trials

2 trials available for lactic acid and Acidosis, Respiratory

ArticleYear
Comparison of pH-stat versus Alpha-stat during hypothermic cardiopulmonary bypass in the prevention and control of acidosis in cardiac surgery.
    Artificial organs, 2004, Volume: 28, Issue:4

    Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Aged; Body Temperature; Carbon Dioxide; Coronary Arter

2004
Inspiratory pressure support prolongs exercise induced lactataemia in severe COPD.
    Thorax, 2000, Volume: 55, Issue:7

    Topics: Acidosis, Respiratory; Aged; Dyspnea; Exercise Therapy; Forced Expiratory Volume; Humans; Hydrogen-I

2000

Other Studies

27 other studies available for lactic acid and Acidosis, Respiratory

ArticleYear
Neuroapoptosis in newborns with respiratory acidosis at birth.
    Clinical biochemistry, 2019, Volume: 74

    Topics: Acidosis, Respiratory; Adolescent; Adult; Apoptosis; Biomarkers; Blood Gas Analysis; Brain; Carbon D

2019
Salbutamol-induced lactic acidosis in status asthmaticus survivor.
    BMC pulmonary medicine, 2021, Jan-12, Volume: 21, Issue:1

    Topics: Acidosis; Acidosis, Lactic; Acidosis, Respiratory; Adrenergic beta-2 Receptor Agonists; Adult; Albut

2021
Acid-base patterns in acute severe asthma.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 2013, Volume: 50, Issue:10

    Topics: Acidosis, Respiratory; Acute Disease; Adult; Aged; Aged, 80 and over; Alkalosis, Respiratory; Asthma

2013
Hypercapnic thresholds for embryonic acid-base metabolic compensation and hematological regulation during CO2 challenges in layer and broiler chicken strains.
    Respiratory physiology & neurobiology, 2015, Aug-15, Volume: 215

    Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Analysis of Variance; Animals; Carbon Dioxide; Chick E

2015
White sturgeon (Acipenser transmontanus) acid-base regulation differs in response to different types of acidoses.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2017, Volume: 187, Issue:7

    Topics: Acid-Base Equilibrium; Acidosis, Lactic; Acidosis, Respiratory; Animals; Brain; Carbon Dioxide; Chlo

2017
Increased steady-state VO2 and larger O2 deficit with CO2 inhalation during exercise.
    Acta physiologica (Oxford, England), 2012, Volume: 204, Issue:3

    Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Administration, Inhalation; Adult; Analysis of Varianc

2012
Mixed acid-base disorders, hydroelectrolyte imbalance and lactate production in hypercapnic respiratory failure: the role of noninvasive ventilation.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Acidosis, Respiratory; Aged; Aged, 80 and over; Alkalosis, Respiratory; Blood Gas Analysis; Carbon D

2012
Effect of increased carbon dioxide concentrations on fixed acid production in vitro.
    The American journal of physiology, 1953, Volume: 172, Issue:2

    Topics: Acidosis, Respiratory; Carbon Dioxide; In Vitro Techniques; Lactic Acid

1953
Alexander disease with serial MRS and a new mutation in the glial fibrillary acidic protein gene.
    Neurology, 2003, Oct-14, Volume: 61, Issue:7

    Topics: Acidosis, Respiratory; Alexander Disease; Basal Ganglia; Choline; Creatine; Disease Progression; DNA

2003
Lactate uptake by skeletal bone in anoxic turtles, Trachemys scripta.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2007, Volume: 146, Issue:3

    Topics: Acidosis, Respiratory; Animals; Bone and Bones; Buffers; Cold Temperature; Hypoxia; Lactic Acid; Tur

2007
Effects of 'DIDS', an anion transport blocker, on CSF [HCO3-] in respiratory acidosis.
    Respiration physiology, 1984, Volume: 57, Issue:3

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfo

1984
Newborn puppy cerebral acid-base regulation in experimental asphyxia and recovery.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1984, Volume: 56, Issue:5

    Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Animals; Animals, Newborn; Bicarbonates; Blood-Brain B

1984
Metabolism and transport of L-glutamine and L-alanine by renal tubules of chickens.
    The American journal of physiology, 1983, Volume: 245, Issue:2

    Topics: Acidosis, Respiratory; Alanine; Alkalosis, Respiratory; Animals; Biological Transport; Carbon Dioxid

1983
Role of acidosis in early contractile dysfunction during ischemia: evidence from pHo measurements.
    The American journal of physiology, 1984, Volume: 247, Issue:5 Pt 2

    Topics: Acidosis; Acidosis, Respiratory; Animals; Coronary Disease; Glucose; Hydrogen-Ion Concentration; Lac

1984
Liver adenosine triphosphate (ATP) in hypoxia and hemorrhagic shock.
    The Journal of trauma, 1982, Volume: 22, Issue:9

    Topics: Acidosis, Respiratory; Adenosine Triphosphate; Animals; Arteries; Hydrogen-Ion Concentration; Hypoxi

1982
Effect of lactic and CO2 acidosis on neuronal function following glucose-oxygen deprivation in rat hippocampal slices.
    Brain research, 1994, Aug-22, Volume: 654, Issue:2

    Topics: Acidosis, Lactic; Acidosis, Respiratory; Animals; Carbon Dioxide; Female; Glucose; Hippocampus; Hydr

1994
pH control in rat skeletal muscle during exercise, recovery from exercise, and acute respiratory acidosis.
    Magnetic resonance in medicine, 1994, Volume: 31, Issue:2

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acidosis, Respiratory; Acute Disease; Adenosine Di

1994
Intramyocardial hypercarbic acidosis during cardiac arrest and resuscitation.
    Critical care medicine, 1993, Volume: 21, Issue:6

    Topics: Acidosis, Respiratory; Animals; Carbon Dioxide; Disease Models, Animal; Heart Arrest; Hemodynamics;

1993
Effect of extreme metabolic acidosis on oxygen delivery capacity of the blood--an in vitro investigation of changes in the oxyhemoglobin dissociation curve in blood with pH values of approximately 6.30.
    Critical care medicine, 1997, Volume: 25, Issue:9

    Topics: Acidosis, Lactic; Acidosis, Respiratory; Blood Gas Analysis; Female; Humans; Hydrogen-Ion Concentrat

1997
Systemic and regional pCO2 gradients as markers of intestinal ischaemia.
    Intensive care medicine, 1998, Volume: 24, Issue:6

    Topics: Acidosis, Lactic; Acidosis, Respiratory; Animals; Biomarkers; Carbon Dioxide; Disease Models, Animal

1998
Brain temperature and metabolic responses during umbilical cord occlusion in fetal sheep.
    Pflugers Archiv : European journal of physiology, 1998, Volume: 436, Issue:5

    Topics: Acidosis, Respiratory; Adenosine; Animals; Aorta; Blood Gas Analysis; Blood Glucose; Body Temperatur

1998
Failure of pulmonary acidosis to increase respiratory drive.
    Journal of applied physiology (Bethesda, Md. : 1985), 1992, Volume: 73, Issue:2

    Topics: Acidosis, Respiratory; Anesthesia; Animals; Blood Gas Analysis; Cats; Chemoreceptor Cells; Electroph

1992
The influence of a respiratory acidosis on the exercise blood lactate response.
    European journal of applied physiology and occupational physiology, 1991, Volume: 63, Issue:1

    Topics: Acidosis, Respiratory; Adult; Carbon Dioxide; Exercise; Humans; Lactates; Lactic Acid; Male; Oxygen

1991
Acid homeostasis following partial ischemia in neonatal brain measured in vivo by 31P and 1H nuclear magnetic resonance spectroscopy.
    Journal of neurochemistry, 1990, Volume: 54, Issue:4

    Topics: Acidosis, Respiratory; Acids; Animals; Animals, Newborn; Brain Ischemia; Energy Metabolism; Homeosta

1990
Skeletal muscle lactate release and glycolytic intermediates during hypercapnia.
    Journal of applied physiology (Bethesda, Md. : 1985), 1986, Volume: 60, Issue:2

    Topics: Acidosis, Respiratory; Animals; Carbon Dioxide; Dogs; Female; Glycolysis; Hypercapnia; Lactates; Lac

1986
Effects of acidosis on rat muscle metabolism and performance during heavy exercise.
    The American journal of physiology, 1985, Volume: 248, Issue:3 Pt 1

    Topics: Acidosis; Acidosis, Respiratory; Adenosine Triphosphate; Animals; Bicarbonates; Carbon Dioxide; Elec

1985
[Gas exchange and metabolic functions of the lungs in endotoxic shock].
    Vestnik khirurgii imeni I. I. Grekova, 1985, Volume: 135, Issue:10

    Topics: Acidosis, Respiratory; Animals; Dogs; Female; Hydrogen-Ion Concentration; Hypoxia; Lactates; Lactic

1985