Page last updated: 2024-10-17

lactic acid and Acid-Base Imbalance

lactic acid has been researched along with Acid-Base Imbalance in 86 studies

Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.

Acid-Base Imbalance: Disturbances in the ACID-BASE EQUILIBRIUM of the body.

Research Excerpts

ExcerptRelevanceReference
"Metformin-associated lactic acidosis (MALA) is a rare adverse effect that has significant morbidity and mortality."9.05Osmolar-gap in the setting of metformin-associated lactic acidosis: Case report and a literature review highlighting an apparently unusual association. ( Alamin, M; Elshafei, MN; Mohamed, MFH, 2020)
"To determine the utility of biochemical parameters such as lactic acid (LA), C-reactive protein (CRP), microalbuminuria (MAU), and base deficit (BD) as early markers of complications in the immediate postoperative evolution of elective open gastrointestinal surgeries."7.72Utility of base deficit, lactic acid, microalbuminuria, and C-reactive protein in the early detection of complications in the immediate postoperative evolution. ( Bianchi, RA; Natal, ML; Romero, MC; Silva, NA, 2004)
"The possibility of detecting past hypoxia during the first 2 h after birth by means of blood analyses of hypoxanthine, lactate, base deficit, and pH was investigated in six infants with a 1 min Apgar score of less than or equal to 4."7.66Hypoxanthine as a test of perinatal hypoxia as compared to lactate, base deficit, and pH. ( Bratteby, LE; Swanström, S, 1982)
"Metformin-associated lactic acidosis (MALA) is a rare adverse effect that has significant morbidity and mortality."5.05Osmolar-gap in the setting of metformin-associated lactic acidosis: Case report and a literature review highlighting an apparently unusual association. ( Alamin, M; Elshafei, MN; Mohamed, MFH, 2020)
"Patients with pancreatitis, pneumonia and the general group all shared three common predictive features as core variables, arterial base excess, lactic acid and platelets."3.79Disease-based modeling to predict fluid response in intensive care units. ( Celi, LA; Cismondi, F; Fialho, AS; Finkelstein, SN; Reti, SR; Sousa, JM; Vieira, SM, 2013)
" His blood gas analysis showed a metabolic acidosis caused by renal failure and lactic acidosis combined with a hypochloraemic alkalosis."3.73[A mixed acid-base disorder revealing a cystic dystrophy of aberrant pancreatic tissue]. ( Bedock, B; Dumaine, A; Gauclère, V; Legrand, E; Proust, P; Rozière, A; Tayssir, A, 2006)
"To determine the utility of biochemical parameters such as lactic acid (LA), C-reactive protein (CRP), microalbuminuria (MAU), and base deficit (BD) as early markers of complications in the immediate postoperative evolution of elective open gastrointestinal surgeries."3.72Utility of base deficit, lactic acid, microalbuminuria, and C-reactive protein in the early detection of complications in the immediate postoperative evolution. ( Bianchi, RA; Natal, ML; Romero, MC; Silva, NA, 2004)
" To study this problem, acute isocapnic metabolic acidosis was induced by HCl or lactic acid infusions in rats, and recovery from acidosis was accomplished by NaHCO3 infusion."3.68Brain pH in acute isocapnic metabolic acidosis and hypoxia: a 31P-nuclear magnetic resonance study. ( Adler, S; Ho, C; Simplaceanu, V, 1990)
"The possibility of detecting past hypoxia during the first 2 h after birth by means of blood analyses of hypoxanthine, lactate, base deficit, and pH was investigated in six infants with a 1 min Apgar score of less than or equal to 4."3.66Hypoxanthine as a test of perinatal hypoxia as compared to lactate, base deficit, and pH. ( Bratteby, LE; Swanström, S, 1982)
"Metabolic acidosis was induced in each horse twice, with a minimum 15-day interval after recovery from the first induction: the first time no treatment was administered (control group) and the second time horses were treated with an intravenous infusion of L84 solution, 100 ml/kg bwt for 5 h, beginning 3 h after the end of HCl infusion."2.84Intravenous administration of a polyionic solution containing 84 mEq/l of lactate resolves experimentally induced hyperchloraemic acidosis in horses. ( Dearo, AC; Fernandes, TM; Flaiban, KK; Lisbôa, JA; Pereira, PF; Romão, FT, 2017)
"The development of fetal hypoxia is related to two essential phenomena: anaerobic glycolysis with lactate production and glycogenolysis to meet energy needs."2.42[Acid base balance in the fetus during labor: pathophysiology and exploration methods]. ( Berkane, N; Bréart, G; Mathieu, E; Uzan, S; Verstraete, L, 2003)
"Severe hyperlactatemia was also more common in CDI patients; during the cardiac procedure, 4 h and 12 h after surgery (p = 0."1.62Prognostic role of perioperative acid-base disturbances on the risk of Clostridioides difficile infection in patients undergoing cardiac surgery. ( Drwiła, R; Hymczak, H; Kapelak, B; Kędziora, A; Plicner, D; Rzucidło-Hymczak, A, 2021)
"The authors evaluated 1,075 trauma patients (mean age, 39 ± 18 yr, with 90% blunt and 10% penetrating injuries and a mortality of 13%)."1.46Comparison of the Prognostic Significance of Initial Blood Lactate and Base Deficit in Trauma Patients. ( Baumgarten, R; Duranteau, J; Gauss, T; Hamada, S; Harrois, A; Langeron, O; Le Manach, Y; Mantz, J; Paugam-Burtz, C; Raux, M; Riou, B; Vigue, B, 2017)
"Gastric necrosis was identified in 12 dogs at the time of surgery and in 4 dogs at necropsy."1.39Evaluation of plasma lactate concentration and base excess at the time of hospital admission as predictors of gastric necrosis and outcome and correlation between those variables in dogs with gastric dilatation-volvulus: 78 cases (2004-2009). ( Beer, KA; Drobatz, KJ; Syring, RS, 2013)
"Elderly trauma patients have worse outcomes than their younger counterparts."1.37Mortality risk stratification in elderly trauma patients based on initial arterial lactate and base deficit levels. ( Bricker, SD; Manasrah, R; Nemtsev, D; Neville, AL; Putnam, BA, 2011)
"Early recognition and treatment of hemorrhagic shock after trauma limits multi-organ failure and mortality."1.35The utility of base deficit and arterial lactate in differentiating major from minor injury in trauma patients with normal vital signs. ( Anderson, T; Paladino, L; Sinert, R; Wallace, D; Yadav, K; Zehtabchi, S, 2008)
"Alcohol and drug use are common in trauma, but do not impair the predictive accuracy of admission lactate and BD in trauma outcome."1.33Lactate and base deficit in trauma: does alcohol or drug use impair their predictive accuracy? ( Dunne, JR; Napolitano, LM; Scalea, TM; Tracy, JK, 2005)
"Prospective, observational study of trauma patients in a Level 1 trauma center."1.32Ethanol and illicit drugs do not affect the diagnostic utility of base deficit and lactate in differentiating minor from major injury in trauma patients. ( Baron, BJ; Lucchesi, M; Sinert, R; Yadav, K; Zehtabchi, S, 2004)
"In a porcine endotoxin shock model, the mixed nonpeptide endothelin receptor antagonist bosentan was administered 2 h after onset of endotoxemia (n = 8)."1.30Cardiopulmonary dysfunction during porcine endotoxin shock is effectively counteracted by the endothelin receptor antagonist bosentan. ( Alving, K; Oldner, A; Rudehill, A; Sollevi, A; Wanecek, M; Weitzberg, E, 1997)

Research

Studies (86)

TimeframeStudies, this research(%)All Research%
pre-199012 (13.95)18.7374
1990's9 (10.47)18.2507
2000's31 (36.05)29.6817
2010's28 (32.56)24.3611
2020's6 (6.98)2.80

Authors

AuthorsStudies
Schork, A1
Moll, K1
Haap, M1
Riessen, R1
Wagner, R1
Trefz, FM1
Lausch, CK1
Rieger, A1
Giertzuch, S1
Lorch, A1
Constable, PD1
Elshafei, MN1
Alamin, M1
Mohamed, MFH1
Davis, JW2
Sue, LP1
Dirks, RC2
Kaups, KL2
Kwok, AM1
Wolfe, MM1
Lilienstein, JT1
Bilello, JF1
Rzucidło-Hymczak, A1
Hymczak, H1
Kędziora, A1
Kapelak, B1
Drwiła, R1
Plicner, D1
Gucyetmez, B2
Tuzuner, F1
Atalan, HK2
Sezerman, U1
Gucyetmez, K1
Telci, L1
Bordes, BM1
Walia, H1
Sebastian, R1
Martin, D1
Tumin, D1
Tobias, JD1
Tran, P1
Drangsholt, E1
Vangstad, M1
Zakharov, S1
Hovda, KE1
Jacobsen, D1
Sakamoto, A1
Naito, H1
Chow, CM1
Agrafiotis, M1
Sileli, M1
Ampatzidou, F1
Keklikoglou, I1
Panousis, P1
Fialho, AS1
Celi, LA1
Cismondi, F1
Vieira, SM1
Reti, SR1
Sousa, JM1
Finkelstein, SN1
Andrewartha, SJ1
Tazawa, H1
Burggren, WW1
Tharwat, M1
Ali, A1
Al-Sobayil, F1
Derar, R1
Al-Hawas, A1
Gustafson, ML1
Hollosi, S1
Chumbe, JT1
Samanta, D1
Modak, A1
Bethea, A1
Folkert, IW1
Sims, CA1
Pascual, JL1
Allen, SR1
Kim, PK1
Schwab, CW1
Holena, DN1
Romão, FT1
Pereira, PF1
Flaiban, KK1
Dearo, AC1
Fernandes, TM1
Lisbôa, JA1
Szrama, J1
Smuszkiewicz, P1
Story, DA1
Caruso, DM1
Matthews, MR1
Raux, M1
Le Manach, Y1
Gauss, T1
Baumgarten, R1
Hamada, S1
Harrois, A1
Riou, B1
Duranteau, J1
Langeron, O1
Mantz, J1
Paugam-Burtz, C1
Vigue, B1
Hebisz, R1
Hebisz, P1
Zatoń, M1
Michalik, K1
Honore, PM1
Joannes-Boyau, O1
Boer, W1
Maciel, AT2
Park, M2
Callaway, DW1
Shapiro, NI1
Donnino, MW1
Baker, C1
Rosen, CL1
Noritomi, DT1
Pontes de Azevedo, LC1
Taniguchi, LU1
da Cruz Neto, LM1
Khosravani, H1
Shahpori, R1
Stelfox, HT1
Kirkpatrick, AW2
Laupland, KB1
Nadeem, M1
Clarke, A1
Dempsey, EM1
Strehlow, MC1
O'Connor, ED1
Fraser, JF1
Effros, RM1
Casaburi, R1
Porszasz, J1
Rehan, VK1
Kogan, A1
Preisman, S1
Bar, A1
Sternik, L1
Lavee, J1
Malachy, A1
Spiegelstein, D1
Berkenstadt, H1
Raanani, E1
Neville, AL1
Nemtsev, D1
Manasrah, R1
Bricker, SD1
Putnam, BA1
Hajjar, LA1
Nakamura, RE1
de Almeida, JP1
Fukushima, JT1
Hoff, PM1
Vincent, JL1
Auler, JO1
Galas, FR1
Mann, C1
Latal, B1
Padden, B1
Scheer, I1
Goebel, G1
Bernet, V1
Ouellet, JF1
Roberts, DJ1
Tiruta, C1
Mercado, M1
Trottier, V1
Dixon, E1
Feliciano, DV1
Ball, CG1
Deetjen, P1
Lichtwarck-Aschoff, M1
Beer, KA1
Syring, RS1
Drobatz, KJ1
Uzan, S1
Berkane, N1
Verstraete, L1
Mathieu, E1
Bréart, G1
Husain, FA1
Martin, MJ1
Mullenix, PS1
Steele, SR1
Elliott, DC1
Tan, HK1
Uchino, S1
Bellomo, R1
Balogh, Z1
McKinley, BA1
Cocanour, CS1
Kozar, RA1
Cox, CS1
Moore, FA1
Bianchi, RA1
Silva, NA1
Natal, ML1
Romero, MC1
Kaplan, LJ1
Kellum, JA2
Zehtabchi, S4
Baron, BJ1
Sinert, R4
Yadav, K2
Lucchesi, M2
Dunne, JR1
Tracy, JK1
Scalea, TM1
Napolitano, LM1
Singhal, R1
Coghill, JE1
Guy, A1
Bradbury, AW1
Adam, DJ1
Scriven, JM1
Dumaine, A1
Tayssir, A1
Gauclère, V1
Proust, P1
Legrand, E1
Rozière, A1
Bedock, B1
Page, B1
Vieillard-Baron, A1
Chergui, K1
Peyrouset, O1
Rabiller, A1
Beauchet, A1
Aegerter, P1
Jardin, F1
Leverve, XM1
Roerick, O1
Seitz, T1
Mauser-Weber, P1
Palmaers, T1
Weyand, M1
Cesnjevar, R1
Berger, NJ1
McNaughton, LR1
Keatley, S1
Wilkerson, DP1
Jones, AM1
Dubin, A1
Menises, MM1
Masevicius, FD1
Moseinco, MC1
Kutscherauer, DO1
Ventrice, E1
Laffaire, E1
Estenssoro, E1
Schaffartzik, W1
Soghoian, S2
Liu, Y1
Carmody, K1
Shah, L1
Kumar, M1
Watanabe, I1
Mayumi, T1
Arishima, T1
Takahashi, H1
Shikano, T1
Nakao, A1
Nagino, M1
Nimura, Y1
Takezawa, J1
Yoshimura, N1
Oshima, Y1
Yoshida, M1
Murakami, H1
Matsuhisa, H1
Yamaguchi, M1
Paladino, L1
Wallace, D1
Anderson, T1
Danilenko, MV1
Glants, RM1
Krivoruchko, RA1
Kaniuk, II1
Mindiuk, MV1
Goodkin, DA1
Krishna, GG1
Narins, RG1
Taitelman, U1
Roy, A1
Raikhlin-Eisenkraft, B1
Hoffer, E1
Aravena, G1
Reinbach, R1
Gonzalez Rios, F1
Katsuta, Y1
Lebedeva, VA1
Filippova, LV1
Bratus', TN1
Iartsev, VN1
Hughes, EF1
Turner, SC1
Brooks, GA1
Swanström, S1
Bratteby, LE1
Hart, GR1
Anderson, RJ1
Crumpler, CP1
Shulkin, A1
Reed, G1
Knochel, JP1
Nimmo, GR1
Mackenzie, SJ1
Walker, S1
Nicol, M1
Grant, IS1
Himpe, D1
Fernández, E1
Román, ID1
Cava, F1
Galán, AI1
Esteller, A1
Muñoz, ME1
Jiménez, R1
Wanecek, M1
Oldner, A1
Rudehill, A1
Sollevi, A1
Alving, K1
Weitzberg, E1
Kincaid, EH1
Miller, PR1
Meredith, JW1
Rahman, N1
Chang, MC1
Porter, JM1
Dunham, CM1
Watson, LA1
Cooper, C1
Bakker, J1
Schieveld, SJ1
Brinkert, W1
Powner, DJ1
Apor, P1
Nordström, L1
Hannon, JP1
Wade, CE1
Bossone, CA1
Hunt, MM1
Coppes, RI1
Loveday, JA1
Coraim, FI1
Haumer, H1
Trubel, W1
Simon, P1
Adler, S1
Simplaceanu, V1
Ho, C1
Vesey, CJ1
Krapez, JR1
Varley, JG1
Cole, PV1
Mochizuki, S1
Taniguchi, M1
Seki, S1
Ishiki, M1
Ozeki, T1
Usui, T1
Nagano, M1
Liu, YH1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of a Transfusion Therapy Using Whole Blood Versus Fractionated Blood Products in the Management of Coagulopathy in Patients Admitted to Hospital for Acute Traumatic Hemorrhage[NCT04431999]Phase 3200 participants (Anticipated)Interventional2021-12-04Recruiting
Fluid Resuscitation Optimization in Surgical Trauma Patients (FROST)[NCT02742974]196 participants (Anticipated)Interventional2015-12-31Recruiting
A Multi-center, Multinational, Randomized, Double-blind, Controlled, Dose Comparison Study to Evaluate Safety and Efficacy of MP4OX Plus Standard Treatment, in Severely Injured Trauma Subjects With Lactic Acidosis Due to Hemorrhagic Shock[NCT01973504]Phase 20 participants (Actual)Interventional2013-12-31Withdrawn (stopped due to Sangart ceased operations)
Sodium Bicarbonate to Treat Severe Acidosis in the Critically Ill : A Multiple Center Randomized Clinical Trial (BICAR-ICU)[NCT02476253]Phase 3400 participants (Anticipated)Interventional2015-05-05Recruiting
Strong Ion Gap as Prognostic Indicator for Adult Patients Admitted With Shock to the Intensive Care Units[NCT02652364]112 participants (Actual)Observational2015-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

11 reviews available for lactic acid and Acid-Base Imbalance

ArticleYear
Osmolar-gap in the setting of metformin-associated lactic acidosis: Case report and a literature review highlighting an apparently unusual association.
    Medicine, 2020, Oct-09, Volume: 99, Issue:41

    Topics: Acid-Base Imbalance; Acidosis, Lactic; Acute Kidney Injury; Diabetes Mellitus, Type 2; Humans; Hypog

2020
Monitoring End Points of Burn Resuscitation.
    Critical care clinics, 2016, Volume: 32, Issue:4

    Topics: Acid-Base Imbalance; Biomarkers; Blood Gas Analysis; Burns; Echocardiography; Endpoint Determination

2016
Early identification of shock in critically ill patients.
    Emergency medicine clinics of North America, 2010, Volume: 28, Issue:1

    Topics: Acid-Base Imbalance; Blood Gas Monitoring, Transcutaneous; Emergency Service, Hospital; Humans; Hypo

2010
[Practical diagnostics of acid-base disorders. Part II: Complex metabolic disturbances].
    Der Anaesthesist, 2012, Volume: 61, Issue:12

    Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Algorithms; Animals; Chlorides; Humans; Lactic Acid; Ser

2012
[Acid base balance in the fetus during labor: pathophysiology and exploration methods].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 2003, Volume: 32, Issue:1 Suppl

    Topics: Acid-Base Imbalance; Female; Fetal Distress; Fetal Hypoxia; Fetal Monitoring; Heart Rate, Fetal; Hum

2003
[Base excess. Parameter with exceptional clinical significance].
    Der Anaesthesist, 2007, Volume: 56, Issue:5

    Topics: Acid-Base Imbalance; Alkalies; Blood Gas Analysis; Critical Illness; Erythrocytes; Humans; Infusions

2007
[Tissue chemoreceptors].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1982, Volume: 68, Issue:2

    Topics: Acid-Base Imbalance; Acidosis; Acidosis, Respiratory; Animals; Bicarbonates; Blood Pressure; Carbon

1982
[Serum lactate level as a indicator of tissue hypoxia in severely ill patients].
    Nederlands tijdschrift voor geneeskunde, 2000, Apr-15, Volume: 144, Issue:16

    Topics: Acid-Base Imbalance; Acidosis, Lactic; Cell Hypoxia; Fluid Therapy; Humans; Lactic Acid; Severity of

2000
Maintaining acid-base balance in organ donors.
    Progress in transplantation (Aliso Viejo, Calif.), 2000, Volume: 10, Issue:2

    Topics: Acid-Base Imbalance; Blood Gas Analysis; Humans; Hydrogen-Ion Concentration; Lactic Acid; Respiratio

2000
[Threshold parameters in clinical practice].
    Orvosi hetilap, 2000, Oct-29, Volume: 141, Issue:44

    Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Acidosis, Lactic; Anaerobic Threshold; Diagnosis, Differ

2000
Lactate measurements in scalp and cord arterial blood.
    Current opinion in obstetrics & gynecology, 2001, Volume: 13, Issue:2

    Topics: Acid-Base Imbalance; Biomarkers; Female; Fetal Blood; Fetal Diseases; Fetal Hypoxia; Humans; Hypoxia

2001

Trials

4 trials available for lactic acid and Acid-Base Imbalance

ArticleYear
Influence of stimulation by electroejaculation on myocardial function, acid-base and electrolyte status, and hematobiochemical profiles in male dromedary camels.
    Theriogenology, 2014, Oct-01, Volume: 82, Issue:6

    Topics: Acid-Base Imbalance; Animals; Camelus; Ejaculation; Electric Stimulation; Heart Rate; Hydrogen-Ion C

2014
Intravenous administration of a polyionic solution containing 84 mEq/l of lactate resolves experimentally induced hyperchloraemic acidosis in horses.
    Equine veterinary journal, 2017, Volume: 49, Issue:1

    Topics: Acid-Base Imbalance; Acidosis; Animals; Cross-Over Studies; Electrolytes; Female; Horse Diseases; Ho

2017
The acid-base effects of continuous hemofiltration with lactate or bicarbonate buffered replacement fluids.
    The International journal of artificial organs, 2003, Volume: 26, Issue:6

    Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Acute Kidney Injury; Adult; Aged; Bicarbonates; Buffers;

2003
Sodium bicarbonate ingestion alters the slow but not the fast phase of VO2 kinetics.
    Medicine and science in sports and exercise, 2006, Volume: 38, Issue:11

    Topics: Acid-Base Imbalance; Adult; Exercise Test; Humans; Hydrogen-Ion Concentration; Kinetics; Lactic Acid

2006

Other Studies

71 other studies available for lactic acid and Acid-Base Imbalance

ArticleYear
Course of lactate, pH and base excess for prediction of mortality in medical intensive care patients.
    PloS one, 2021, Volume: 16, Issue:12

    Topics: Acid-Base Imbalance; Aged; Aged, 80 and over; Female; Hospital Mortality; Humans; Hydrogen-Ion Conce

2021
Acid-base imbalances and the association of blood-gas variables, electrolytes, and biochemical analytes with outcome in hospitalized calves undergoing abdominal surgery.
    Journal of veterinary internal medicine, 2023, Volume: 37, Issue:2

    Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Animals; Cattle; Cattle Diseases; Electrolytes; Emergenc

2023
Admission base deficit is superior to lactate in identifying shock and resuscitative needs in trauma patients.
    American journal of surgery, 2020, Volume: 220, Issue:6

    Topics: Acid-Base Imbalance; Biomarkers; Blood Transfusion; Female; Humans; Injury Severity Score; Lactic Ac

2020
Prognostic role of perioperative acid-base disturbances on the risk of Clostridioides difficile infection in patients undergoing cardiac surgery.
    PloS one, 2021, Volume: 16, Issue:3

    Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Age Factors; Aged; Blood Gas Analysis; Cardiac Surgical

2021
Base-excess chloride; the best approach to evaluate the effect of chloride on the acid-base status: A retrospective study.
    PloS one, 2021, Volume: 16, Issue:4

    Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Aged; APACHE; Chlorides; Critical Illness; Female; Human

2021
Correlation of Lactic Acid and Base Deficit Values Obtained From Arterial and Peripheral Venous Samples in a Pediatric Population During Intraoperative Care.
    Journal of intensive care medicine, 2017, Volume: 32, Issue:10

    Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Adolescent; Child; Child, Preschool; Cross-Sectional Stu

2017
Base deficit is superior to lactate in trauma.
    American journal of surgery, 2018, Volume: 215, Issue:4

    Topics: Acid-Base Imbalance; Biomarkers; Blood Component Transfusion; Blood Gas Analysis; California; Female

2018
The Hypothesis of Circulus Hypoxicus and Its Clinical Relevance in Patients With Methanol Poisoning - An Observational Study of 35 Patients.
    Basic & clinical pharmacology & toxicology, 2018, Volume: 123, Issue:6

    Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Acidosis; Adolescent; Adult; Aged; Blood Gas Analysis; F

2018
Hyperventilation as a strategy for improved repeated sprint performance.
    Journal of strength and conditioning research, 2014, Volume: 28, Issue:4

    Topics: Acid-Base Imbalance; Adaptation, Physiological; Bicycling; Blood Gas Analysis; Ergometry; Exercise T

2014
The base excess gap is not a valid tool for the quantification of unmeasured ions in cardiac surgical patients: a retrospective observational study.
    European journal of anaesthesiology, 2013, Volume: 30, Issue:11

    Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Aged; Carbon Dioxide; Cardiac Surgical Procedures; Criti

2013
Disease-based modeling to predict fluid response in intensive care units.
    Methods of information in medicine, 2013, Volume: 52, Issue:6

    Topics: Acid-Base Imbalance; Adult; Aged; Aged, 80 and over; Blood Pressure; Cohort Studies; Computer Simula

2013
Acute regulation of hematocrit and acid-base balance in chicken embryos in response to severe intrinsic hypercapnic hypoxia.
    Respiratory physiology & neurobiology, 2014, May-01, Volume: 195

    Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Animals; Chick Embryo; Erythrocyte Indices; Erythrocytes

2014
The effect of ethanol on lactate and base deficit as predictors of morbidity and mortality in trauma.
    The American journal of emergency medicine, 2015, Volume: 33, Issue:5

    Topics: Acid-Base Imbalance; Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Ethanol; Female; Hospit

2015
Initial venous lactate levels in patients with isolated penetrating extremity trauma: a retrospective cohort study.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2015, Volume: 41, Issue:2

    Topics: Acid-Base Imbalance; Adult; Aged; Female; Humans; Lactic Acid; Male; Middle Aged; Retrospective Stud

2015
Non-lactate strong ion difference: a clearer picture.
    Journal of anesthesia, 2016, Volume: 30, Issue:3

    Topics: Acid-Base Imbalance; Adult; Aged; Aged, 80 and over; APACHE; Chlorides; Critical Care; Critical Illn

2016
An acid-base disorders analysis with the use of the Stewart approach in patients with sepsis treated in an intensive care unit.
    Anaesthesiology intensive therapy, 2016, Volume: 48, Issue:3

    Topics: Acid-Base Imbalance; Acidosis; Adult; Aged; Algorithms; Alkalosis; Blood Gas Analysis; Critical Care

2016
Stewart Acid-Base: A Simplified Bedside Approach.
    Anesthesia and analgesia, 2016, Volume: 123, Issue:2

    Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Biomarkers; Chlorides; Fluid Therapy; Humans; Hydrogen-I

2016
Comparison of the Prognostic Significance of Initial Blood Lactate and Base Deficit in Trauma Patients.
    Anesthesiology, 2017, Volume: 126, Issue:3

    Topics: Academic Medical Centers; Acid-Base Imbalance; Adult; Biomarkers; Cohort Studies; Female; France; Ho

2017
Peak oxygen uptake in a sprint interval testing protocol vs. maximal oxygen uptake in an incremental testing protocol and their relationship with cross-country mountain biking performance.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2017, Volume: 42, Issue:4

    Topics: Acid-Base Imbalance; Adult; Altitude; Athletes; Athletic Performance; Bicycling; Exercise Test; Exer

2017
Strong ion gap and outcome after cardiac arrest: another nail in the coffin of traditional acid-base quantification.
    Intensive care medicine, 2009, Volume: 35, Issue:2

    Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Acidosis; Analysis of Variance; Biomechanical Phenomena;

2009
Differences in acid-base behavior between intensive care unit survivors and nonsurvivors using both a physicochemical and a standard base excess approach: a prospective, observational study.
    Journal of critical care, 2009, Volume: 24, Issue:4

    Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Acidosis; Adult; Aged; Chlorides; Female; Humans; Hydrog

2009
Serum lactate and base deficit as predictors of mortality in normotensive elderly blunt trauma patients.
    The Journal of trauma, 2009, Volume: 66, Issue:4

    Topics: Acid-Base Imbalance; Aged; Aged, 80 and over; Area Under Curve; Comorbidity; Female; Hospital Mortal

2009
Effect of PaCO2 variation on standard base excess value in critically ill patients.
    Journal of critical care, 2009, Volume: 24, Issue:4

    Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Adult; Aged; Carbon Dioxide; Critical Illness; Female; H

2009
Occurrence and adverse effect on outcome of hyperlactatemia in the critically ill.
    Critical care (London, England), 2009, Volume: 13, Issue:3

    Topics: Acid-Base Imbalance; Alberta; Critical Illness; Female; Hospital Mortality; Humans; Incidence; Inten

2009
Day 1 serum lactate values in preterm infants less than 32 weeks gestation.
    European journal of pediatrics, 2010, Volume: 169, Issue:6

    Topics: Acid-Base Imbalance; Biomarkers; Humans; Infant, Newborn; Infant, Premature; Infant, Very Low Birth

2010
Hyperlactatemia in critical illness and cardiac surgery.
    Critical care (London, England), 2010, Volume: 14, Issue:3

    Topics: Acid-Base Imbalance; Cardiac Surgical Procedures; Critical Illness; Humans; Intensive Care Units; La

2010
Assessment of exhaled breath condensate pH.
    American journal of respiratory and critical care medicine, 2011, Apr-01, Volume: 183, Issue:7

    Topics: Acid-Base Imbalance; Breath Tests; Exhalation; Female; Humans; Hydrogen-Ion Concentration; Lactic Ac

2011
The impact of hyperlactatemia on postoperative outcome after adult cardiac surgery.
    Journal of anesthesia, 2012, Volume: 26, Issue:2

    Topics: Acid-Base Imbalance; Cardiac Surgical Procedures; Female; Hospitalization; Humans; Intensive Care Un

2012
Mortality risk stratification in elderly trauma patients based on initial arterial lactate and base deficit levels.
    The American surgeon, 2011, Volume: 77, Issue:10

    Topics: Acid-Base Imbalance; Aged; Aged, 80 and over; Area Under Curve; Biomarkers; California; Female; Hosp

2011
Lactate and base deficit are predictors of mortality in critically ill patients with cancer.
    Clinics (Sao Paulo, Brazil), 2011, Volume: 66, Issue:12

    Topics: Acid-Base Imbalance; Critical Illness; Female; Hospital Mortality; Humans; Lactic Acid; Male; Middle

2011
Acid-base parameters for predicting magnetic resonance imaging measures of neurologic outcome after perinatal hypoxia-ischemia: is the strong ion gap superior to base excess and lactate?
    American journal of perinatology, 2012, Volume: 29, Issue:5

    Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Brain; Cohort Studies; Female; Humans; Hypothermia, Indu

2012
Admission base deficit and lactate levels in Canadian patients with blunt trauma: are they useful markers of mortality?
    The journal of trauma and acute care surgery, 2012, Volume: 72, Issue:6

    Topics: Acid-Base Imbalance; Adult; Aged; Alberta; Analysis of Variance; Biomarkers; Blood Gas Analysis; Coh

2012
Evaluation of plasma lactate concentration and base excess at the time of hospital admission as predictors of gastric necrosis and outcome and correlation between those variables in dogs with gastric dilatation-volvulus: 78 cases (2004-2009).
    Journal of the American Veterinary Medical Association, 2013, Jan-01, Volume: 242, Issue:1

    Topics: Acid-Base Imbalance; Animals; Dog Diseases; Dogs; Female; Gastric Dilatation; Lactic Acid; Male; Nec

2013
Serum lactate and base deficit as predictors of mortality and morbidity.
    American journal of surgery, 2003, Volume: 185, Issue:5

    Topics: Abdomen; Acid-Base Imbalance; Analysis of Variance; APACHE; Critical Illness; Humans; Hydrogen-Ion C

2003
Serum lactate and base deficit as predictors of mortality and morbidity.
    American journal of surgery, 2003, Volume: 185, Issue:5

    Topics: Abdomen; Acid-Base Imbalance; Analysis of Variance; APACHE; Critical Illness; Humans; Hydrogen-Ion C

2003
Serum lactate and base deficit as predictors of mortality and morbidity.
    American journal of surgery, 2003, Volume: 185, Issue:5

    Topics: Abdomen; Acid-Base Imbalance; Analysis of Variance; APACHE; Critical Illness; Humans; Hydrogen-Ion C

2003
Serum lactate and base deficit as predictors of mortality and morbidity.
    American journal of surgery, 2003, Volume: 185, Issue:5

    Topics: Abdomen; Acid-Base Imbalance; Analysis of Variance; APACHE; Critical Illness; Humans; Hydrogen-Ion C

2003
Serum lactate and base deficit as predictors of mortality and morbidity.
    American journal of surgery, 2003, Volume: 185, Issue:5

    Topics: Abdomen; Acid-Base Imbalance; Analysis of Variance; APACHE; Critical Illness; Humans; Hydrogen-Ion C

2003
Serum lactate and base deficit as predictors of mortality and morbidity.
    American journal of surgery, 2003, Volume: 185, Issue:5

    Topics: Abdomen; Acid-Base Imbalance; Analysis of Variance; APACHE; Critical Illness; Humans; Hydrogen-Ion C

2003
Serum lactate and base deficit as predictors of mortality and morbidity.
    American journal of surgery, 2003, Volume: 185, Issue:5

    Topics: Abdomen; Acid-Base Imbalance; Analysis of Variance; APACHE; Critical Illness; Humans; Hydrogen-Ion C

2003
Serum lactate and base deficit as predictors of mortality and morbidity.
    American journal of surgery, 2003, Volume: 185, Issue:5

    Topics: Abdomen; Acid-Base Imbalance; Analysis of Variance; APACHE; Critical Illness; Humans; Hydrogen-Ion C

2003
Serum lactate and base deficit as predictors of mortality and morbidity.
    American journal of surgery, 2003, Volume: 185, Issue:5

    Topics: Abdomen; Acid-Base Imbalance; Analysis of Variance; APACHE; Critical Illness; Humans; Hydrogen-Ion C

2003
Patients with impending abdominal compartment syndrome do not respond to early volume loading.
    American journal of surgery, 2003, Volume: 186, Issue:6

    Topics: Abdomen; Acid-Base Imbalance; Adult; Blood Transfusion; Compartment Syndromes; Crystalloid Solutions

2003
Utility of base deficit, lactic acid, microalbuminuria, and C-reactive protein in the early detection of complications in the immediate postoperative evolution.
    Clinical biochemistry, 2004, Volume: 37, Issue:5

    Topics: Acid-Base Imbalance; Adult; Aged; Albuminuria; Argentina; Biomarkers; C-Reactive Protein; Creatinine

2004
Initial pH, base deficit, lactate, anion gap, strong ion difference, and strong ion gap predict outcome from major vascular injury.
    Critical care medicine, 2004, Volume: 32, Issue:5

    Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Adult; Age Distribution; Analysis of Variance; Biomechan

2004
Ethanol and illicit drugs do not affect the diagnostic utility of base deficit and lactate in differentiating minor from major injury in trauma patients.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2004, Volume: 11, Issue:10

    Topics: Acid-Base Imbalance; Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Emergency Medicin

2004
Lactate and base deficit in trauma: does alcohol or drug use impair their predictive accuracy?
    The Journal of trauma, 2005, Volume: 58, Issue:5

    Topics: Acid-Base Imbalance; Adult; Age Distribution; Alcohol Drinking; Biomarkers; Cocaine-Related Disorder

2005
Serum lactate and base deficit as predictors of mortality after ruptured abdominal aortic aneurysm repair.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2005, Volume: 30, Issue:3

    Topics: Acid-Base Imbalance; Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal; Aortic Rupture; Blood Vess

2005
[A mixed acid-base disorder revealing a cystic dystrophy of aberrant pancreatic tissue].
    Annales francaises d'anesthesie et de reanimation, 2006, Volume: 25, Issue:2

    Topics: Acid-Base Imbalance; Acidosis; Acute Kidney Injury; Adult; Alkalosis; Blood Chemical Analysis; Blood

2006
Early veno-venous haemodiafiltration for sepsis-related multiple organ failure.
    Critical care (London, England), 2005, Volume: 9, Issue:6

    Topics: Acid-Base Imbalance; Acute Kidney Injury; Electrolytes; Female; Hemofiltration; Humans; Lactic Acid;

2005
Lactate in the intensive care unit: pyromaniac, sentinel or fireman?
    Critical care (London, England), 2005, Volume: 9, Issue:6

    Topics: Acid-Base Imbalance; Biomarkers; Critical Care; Energy Metabolism; Humans; Lactic Acid; Oxygen Consu

2005
Low-flow perfusion via the innominate artery during aortic arch operations provides only limited somatic circulatory support.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2006, Volume: 29, Issue:4

    Topics: Acid-Base Imbalance; Animals; Animals, Newborn; Aorta, Thoracic; Body Temperature; Brachiocephalic T

2006
Comparison of three different methods of evaluation of metabolic acid-base disorders.
    Critical care medicine, 2007, Volume: 35, Issue:5

    Topics: Acid-Base Imbalance; Aged; Albumins; Anions; Area Under Curve; Bicarbonates; Female; Humans; Hydroge

2007
Identifying traumatic brain injury in patients with isolated head trauma: are arterial lactate and base deficit as helpful as in polytrauma?
    Emergency medicine journal : EMJ, 2007, Volume: 24, Issue:5

    Topics: Acid-Base Imbalance; Adult; Biomarkers; Brain Injuries; Cohort Studies; Female; Humans; Lactic Acid;

2007
Hyperlactemia can predict the prognosis of liver resection.
    Shock (Augusta, Ga.), 2007, Volume: 28, Issue:1

    Topics: Acid-Base Imbalance; Aged; Bilirubin; Female; Hepatectomy; Humans; Lactic Acid; Male; Middle Aged; P

2007
Continuous hemodiafiltration during cardiopulmonary bypass in infants.
    Asian cardiovascular & thoracic annals, 2007, Volume: 15, Issue:5

    Topics: Acid-Base Imbalance; Calcium; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Heart Defects, Co

2007
Utility of Stewart's strong ion difference as a predictor of major injury after trauma in the ED.
    The American journal of emergency medicine, 2007, Volume: 25, Issue:8

    Topics: Acid-Base Imbalance; Acidosis; Adolescent; Adult; Aged; Aged, 80 and over; Bicarbonates; Emergency S

2007
The utility of base deficit and arterial lactate in differentiating major from minor injury in trauma patients with normal vital signs.
    Resuscitation, 2008, Volume: 77, Issue:3

    Topics: Acid-Base Imbalance; Adolescent; Adult; Aged; Aged, 80 and over; Bicarbonates; Female; Humans; Injur

2008
[Correction of acid-base imbalance by administering various transfusion media to patients after heart surgery].
    Sovetskaia meditsina, 1983, Issue:1

    Topics: Acid-Base Imbalance; Adolescent; Adult; Bicarbonates; Female; Humans; Infusions, Parenteral; Lactate

1983
The role of the anion gap in detecting and managing mixed metabolic acid-base disorders.
    Clinics in endocrinology and metabolism, 1984, Volume: 13, Issue:2

    Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Acidosis; Alkalosis; Alkalosis, Respiratory; Anti-Bacter

1984
The effect of monoacetin and calcium chloride on acid-base balance and survival in experimental sodium fluoroacetate poisoning.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1983, Volume: 6

    Topics: Acid-Base Imbalance; Animals; Antidotes; Blood Pressure; Calcium; Calcium Chloride; Cats; Fluoroacet

1983
[Surgery-linked alterations in the level of lactate and of the acid-base equilibrium at the post-operative stage].
    Cellular and molecular biology, 1983, Volume: 29, Issue:4

    Topics: Acid-Base Imbalance; Adolescent; Adult; Aged; Female; Humans; Lactates; Lactic Acid; Male; Middle Ag

1983
[Acid-base disturbance in patients with compensated liver cirrhosis and chronic hepatitis (author's transl)].
    Nihon Ika Daigaku zasshi, 1981, Volume: 48, Issue:6

    Topics: Acid-Base Imbalance; Adult; Carbon Dioxide; Chronic Disease; Female; Hepatitis; Humans; Lactates; La

1981
Effects of glycogen depletion and pedaling speed on "anaerobic threshold".
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1982, Volume: 52, Issue:6

    Topics: 3-Hydroxybutyric Acid; Acid-Base Imbalance; Adult; Anaerobiosis; Analysis of Variance; Blood Glucose

1982
Hypoxanthine as a test of perinatal hypoxia as compared to lactate, base deficit, and pH.
    Pediatric research, 1982, Volume: 16, Issue:2

    Topics: Acid-Base Imbalance; Asphyxia Neonatorum; Humans; Hydrogen-Ion Concentration; Hypoxanthine; Hypoxant

1982
Epidemic classical heat stroke: clinical characteristics and course of 28 patients.
    Medicine, 1982, Volume: 61, Issue:3

    Topics: Acid-Base Imbalance; Age Factors; Aged; Climate; Disease Outbreaks; Female; Heat Exhaustion; Humans;

1982
Acid-base responses to high-volume haemofiltration in the critically ill.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1993, Volume: 8, Issue:9

    Topics: Acid-Base Imbalance; Acute Kidney Injury; Aged; Aged, 80 and over; Critical Illness; Female; Hemofil

1993
Anion gap, lactate, and acid-base status after cardiac surgery.
    Critical care medicine, 1993, Volume: 21, Issue:5

    Topics: Acid-Base Imbalance; Coronary Artery Bypass; Humans; Intraoperative Complications; Lactates; Lactic

1993
Acid-base disturbances in the rabbit during experimental hepatic parasitosis.
    Parasitology research, 1996, Volume: 82, Issue:6

    Topics: Acid-Base Imbalance; Animals; Bicarbonates; Blood Gas Monitoring, Transcutaneous; Coccidiosis; Disea

1996
Cardiopulmonary dysfunction during porcine endotoxin shock is effectively counteracted by the endothelin receptor antagonist bosentan.
    Shock (Augusta, Ga.), 1997, Volume: 7, Issue:5

    Topics: Acid-Base Imbalance; Animals; Bosentan; Cardiovascular Diseases; Endothelin Receptor Antagonists; En

1997
Elevated arterial base deficit in trauma patients: a marker of impaired oxygen utilization.
    Journal of the American College of Surgeons, 1998, Volume: 187, Issue:4

    Topics: Acid-Base Imbalance; Adult; Aged; Cell Respiration; Female; Hemodynamics; Humans; Lactic Acid; Linea

1998
Elevated arterial base deficit.
    Journal of the American College of Surgeons, 1999, Volume: 188, Issue:3

    Topics: Acid-Base Imbalance; Arteries; Humans; Lactic Acid; Oxygen Consumption; Time Factors; Wounds and Inj

1999
Base deficit level indicating major injury is increased with ethanol.
    The Journal of emergency medicine, 2000, Volume: 18, Issue:2

    Topics: Abdominal Injuries; Acid-Base Imbalance; Alcohol Drinking; Cohort Studies; Comorbidity; Ethanol; Eva

2000
Blood gas and acid-base status of conscious pigs subjected to fixed-volume hemorrhage and resuscitated with hypertonic saline dextran.
    Circulatory shock, 1990, Volume: 32, Issue:1

    Topics: Acid-Base Imbalance; Animals; Bicarbonates; Blood; Carbon Dioxide; Dextrans; Hemorrhage; Hydrogen-Io

1990
Regulation of acid-base state with hemofiltration in circulatory shock in patients after open heart surgery.
    Contributions to nephrology, 1991, Volume: 93

    Topics: Acid-Base Imbalance; Ammonia; Bicarbonates; Cardiac Surgical Procedures; Glutamine; Hemofiltration;

1991
Brain pH in acute isocapnic metabolic acidosis and hypoxia: a 31P-nuclear magnetic resonance study.
    The American journal of physiology, 1990, Volume: 258, Issue:1 Pt 2

    Topics: Acid-Base Imbalance; Acidosis; Animals; Brain; Hydrochloric Acid; Hydrogen; Hydrogen-Ion Concentrati

1990
The antidotal action of thiosulfate following acute nitroprusside infusion in dogs.
    Anesthesiology, 1985, Volume: 62, Issue:4

    Topics: Acid-Base Imbalance; Animals; Antidotes; Dogs; Erythrocytes; Ferricyanides; Hydrogen Cyanide; Infusi

1985
Acid-base changes in ischemic myocardium and intervention with hypothermia or bicarbonate.
    Japanese circulation journal, 1988, Volume: 52, Issue:7

    Topics: Acid-Base Imbalance; Animals; Bicarbonates; Calcium; Carbon Dioxide; Coronary Circulation; Coronary

1988
[Significance of lactate, pyruvate and anion gap in the diagnosis of complicated acid-base disturbances in chronic cor pulmonale].
    Zhonghua jie he he hu xi xi ji bing za zhi = Chinese journal of tuberculosis and respiratory diseases, 1986, Volume: 9, Issue:6

    Topics: Acid-Base Equilibrium; Acid-Base Imbalance; Adult; Female; Humans; Lactates; Lactic Acid; Male; Midd

1986