lactic acid has been researched along with Absence Status in 25 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The lithium-pilocarpine model of status epilepticus is a well-known animal model of temporal lobe epilepsy." | 7.81 | Early metabolic responses to lithium/pilocarpine-induced status epilepticus in rat brain. ( Hillert, MH; Imran, I; Klein, J, 2015) |
| "To evaluate the efficacy and tolerability of intravenous (IV) levetiracetam in refractory status epilepticus of migrating partial seizures in infancy (MPSI)." | 7.75 | Intravenous levetiracetam terminates refractory status epilepticus in two patients with migrating partial seizures in infancy. ( Balestri, M; Bianchi, R; Cilio, MR; Di Capua, M; Giovannini, S; Onofri, A; Vigevano, F, 2009) |
| " Here, we present data using in vivo magnetic resonance spectroscopy (MRS) optimized for the detection of glutamate to identify changes that evolve following kainic acid (KA)-induced status epilepticus." | 7.75 | In vivo glutamate decline associated with kainic acid-induced status epilepticus. ( Crawford, EL; Hsu, O; Mayer, D; Pfefferbaum, A; Rohlfing, T; Sullivan, EV; Vinco, S; Zahr, NM, 2009) |
| "The correlation between seizure-induced hypermetabolism and subsequent neuronal damage was studied in 10-day-old (P10), 21-day-old (P21), and adult rats subjected to lithium-pilocarpine status epilepticus (SE)." | 7.70 | Correlation between hypermetabolism and neuronal damage during status epilepticus induced by lithium and pilocarpine in immature and adult rats. ( Boyet, S; Dubé, C; Fernandes, MJ; Marescaux, C; Nehlig, A, 1999) |
| "The brain uptake of phenobarbital during prolonged status epilepticus (3 h) was studied in paralyzed, ventilated sheep." | 7.67 | Brain phenobarbital uptake during prolonged status epilepticus. ( Benowitz, NL; Bronstein, J; Copeland, JR; Jacob, P; Simon, RP, 1987) |
| " Furthermore, real-time measurement of lactate and oxygen concentration dynamics concurrently with network electrical activity during status epilepticus induced by 4-aminopyridine (4-AP) demonstrated phasic changes in lactate levels that correlated with bursts of electrical activity, while tonic levels of lactate remained stable during seizures." | 4.84 | Amperometric bio-sensing of lactate and oxygen concurrently with local field potentials during status epilepticus. ( Barbosa, RM; Fernandes, E; Gerhardt, GA; Ledo, A, 2024) |
| "The lithium-pilocarpine model of status epilepticus is a well-known animal model of temporal lobe epilepsy." | 3.81 | Early metabolic responses to lithium/pilocarpine-induced status epilepticus in rat brain. ( Hillert, MH; Imran, I; Klein, J, 2015) |
| "To evaluate the efficacy and tolerability of intravenous (IV) levetiracetam in refractory status epilepticus of migrating partial seizures in infancy (MPSI)." | 3.75 | Intravenous levetiracetam terminates refractory status epilepticus in two patients with migrating partial seizures in infancy. ( Balestri, M; Bianchi, R; Cilio, MR; Di Capua, M; Giovannini, S; Onofri, A; Vigevano, F, 2009) |
| " Here, we present data using in vivo magnetic resonance spectroscopy (MRS) optimized for the detection of glutamate to identify changes that evolve following kainic acid (KA)-induced status epilepticus." | 3.75 | In vivo glutamate decline associated with kainic acid-induced status epilepticus. ( Crawford, EL; Hsu, O; Mayer, D; Pfefferbaum, A; Rohlfing, T; Sullivan, EV; Vinco, S; Zahr, NM, 2009) |
| "The correlation between seizure-induced hypermetabolism and subsequent neuronal damage was studied in 10-day-old (P10), 21-day-old (P21), and adult rats subjected to lithium-pilocarpine status epilepticus (SE)." | 3.70 | Correlation between hypermetabolism and neuronal damage during status epilepticus induced by lithium and pilocarpine in immature and adult rats. ( Boyet, S; Dubé, C; Fernandes, MJ; Marescaux, C; Nehlig, A, 1999) |
| " Infarcts in substantia nigra pars reticulata were evoked by prolonged pilocarpine-induced status epilepticus." | 3.68 | Immunohistochemical studies with antibodies to neurofilament proteins on axonal damage in experimental focal lesions in rat. ( Bellander, BM; Ingvar, M; Meller, D; Schmidt-Kastner, R, 1993) |
| "The purpose of these experiments was to determine whether flurothyl-induced status epilepticus causes progressive decline of brain high-energy phosphates and progressive increase in brain lactate in neonatal dogs who are paralyzed and oxygenated." | 3.68 | Brain energy state and lactate metabolism during status epilepticus in the neonatal dog: in vivo 31P and 1H nuclear magnetic resonance study. ( Aquila, WJ; Chen, B; Gore, JC; Petroff, OA; Young, RS, 1991) |
| "The brain uptake of phenobarbital during prolonged status epilepticus (3 h) was studied in paralyzed, ventilated sheep." | 3.67 | Brain phenobarbital uptake during prolonged status epilepticus. ( Benowitz, NL; Bronstein, J; Copeland, JR; Jacob, P; Simon, RP, 1987) |
| "Video-EEG recordings evaluated seizure duration, severity, and immunohistochemistry was used to determine neuronal loss." | 1.91 | Glycolytic lactate production supports status epilepticus in experimental animals. ( Kapur, J; Kasprzak, I; Sharma, S; Skwarzynska, D; Sun, H; Williamson, J, 2023) |
| "The effect of seizure activity on CSF lactate concentration in dogs is unknown." | 1.56 | Cerebrospinal fluid lactate concentrations in dogs with seizure disorders. ( Early, PJ; Green, L; Guevar, J; Lau, J; Lee, CS; Mariani, CL; Muñana, KR; Nye, CJ; Olby, NJ; Ruterbories, L; Tokarz, DA; Zidan, N, 2020) |
| "Status epilepticus was evoked in half of the sedentary and trained rats by a repetitive intraperitoneal injection of KA in low subconvulsive doses." | 1.46 | Effect of Training at Lactate Threshold Intensity on Maximal Time to Exhaustion, Depression and Anxiety Behaviour of Spontaneously Hypertensive Rats after Kainate-Induced Status Epilepticus. ( Andreev, GG; Georgiev, NG; Georgieva, KN; Hadjieva, MS; Shishmanova-Doseva, MS; Tchekalarova, JD; Terzieva, DD, 2017) |
| "Findings were correlated with seizure types, seizure etiology (symptomatic, cryptogenic, occasional seizure), and seizure duration." | 1.42 | Effect of epileptic seizures on the cerebrospinal fluid--A systematic retrospective analysis. ( Brettschneider, J; Fauser, S; Hoppner, AC; Jobs, C; Kerling, F; Tumani, H, 2015) |
| "Alpers syndrome is a progressive encephalopathy of early onset, characterized by rapid and severe developmental delay, intractable seizures and liver involvement in a previously healthy child." | 1.31 | Respiratory chain deficiency in Alpers syndrome. ( Chrétien, D; Cormier-Daire, V; de Lonlay, P; Gauthier-Villars, M; Jacquemin, E; Landrieu, P; Munnich, A; Rötig, A; Rustin, P, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (24.00) | 18.7374 |
| 1990's | 4 (16.00) | 18.2507 |
| 2000's | 6 (24.00) | 29.6817 |
| 2010's | 3 (12.00) | 24.3611 |
| 2020's | 6 (24.00) | 2.80 |
| Authors | Studies |
|---|---|
| Süße, M | 1 |
| Gag, K | 1 |
| Hamann, L | 1 |
| Hannich, MJ | 1 |
| von Podewils, F | 1 |
| Skwarzynska, D | 1 |
| Sun, H | 1 |
| Kasprzak, I | 1 |
| Sharma, S | 1 |
| Williamson, J | 1 |
| Kapur, J | 1 |
| Tan, THL | 1 |
| Sanfilippo, P | 1 |
| Colman, B | 1 |
| Perucca, P | 1 |
| Kwan, P | 1 |
| O'Brien, TJ | 1 |
| Monif, M | 1 |
| Fernandes, E | 1 |
| Ledo, A | 1 |
| Gerhardt, GA | 1 |
| Barbosa, RM | 1 |
| Hurth, H | 1 |
| Schlak, D | 1 |
| Ebner, FH | 1 |
| Mariani, CL | 1 |
| Nye, CJ | 1 |
| Ruterbories, L | 1 |
| Tokarz, DA | 1 |
| Green, L | 1 |
| Lau, J | 1 |
| Zidan, N | 1 |
| Early, PJ | 1 |
| Muñana, KR | 1 |
| Olby, NJ | 1 |
| Lee, CS | 1 |
| Guevar, J | 1 |
| Georgieva, KN | 1 |
| Hadjieva, MS | 1 |
| Shishmanova-Doseva, MS | 1 |
| Terzieva, DD | 1 |
| Georgiev, NG | 1 |
| Andreev, GG | 1 |
| Tchekalarova, JD | 1 |
| Tumani, H | 1 |
| Jobs, C | 1 |
| Brettschneider, J | 1 |
| Hoppner, AC | 1 |
| Kerling, F | 1 |
| Fauser, S | 1 |
| Imran, I | 1 |
| Hillert, MH | 1 |
| Klein, J | 1 |
| Cilio, MR | 1 |
| Bianchi, R | 1 |
| Balestri, M | 1 |
| Onofri, A | 1 |
| Giovannini, S | 1 |
| Di Capua, M | 1 |
| Vigevano, F | 1 |
| Zahr, NM | 1 |
| Crawford, EL | 1 |
| Hsu, O | 1 |
| Vinco, S | 1 |
| Mayer, D | 1 |
| Rohlfing, T | 1 |
| Sullivan, EV | 1 |
| Pfefferbaum, A | 1 |
| Slais, K | 1 |
| Vorisek, I | 1 |
| Zoremba, N | 1 |
| Homola, A | 1 |
| Dmytrenko, L | 1 |
| Sykova, E | 1 |
| Vespa, PM | 1 |
| Miller, C | 1 |
| McArthur, D | 1 |
| Eliseo, M | 1 |
| Etchepare, M | 1 |
| Hirt, D | 1 |
| Glenn, TC | 1 |
| Martin, N | 1 |
| Hovda, D | 1 |
| Meller, D | 1 |
| Bellander, BM | 1 |
| Schmidt-Kastner, R | 1 |
| Ingvar, M | 2 |
| Ebisu, T | 1 |
| Rooney, WD | 1 |
| Graham, SH | 1 |
| Mancuso, A | 1 |
| Weiner, MW | 1 |
| Maudsley, AA | 1 |
| Fernandes, MJ | 1 |
| Dubé, C | 1 |
| Boyet, S | 1 |
| Marescaux, C | 1 |
| Nehlig, A | 1 |
| Fornai, F | 1 |
| Bassi, L | 1 |
| Gesi, M | 1 |
| Giorgi, FS | 1 |
| Guerrini, R | 1 |
| Bonaccorsi, I | 1 |
| Alessandrì, MG | 1 |
| Gauthier-Villars, M | 1 |
| Landrieu, P | 1 |
| Cormier-Daire, V | 1 |
| Jacquemin, E | 1 |
| Chrétien, D | 1 |
| Rötig, A | 1 |
| Rustin, P | 1 |
| Munnich, A | 1 |
| de Lonlay, P | 1 |
| Young, RS | 2 |
| Petroff, OA | 2 |
| Chen, B | 1 |
| Gore, JC | 1 |
| Aquila, WJ | 1 |
| Simon, RP | 2 |
| Copeland, JR | 1 |
| Benowitz, NL | 1 |
| Jacob, P | 1 |
| Bronstein, J | 1 |
| Prichard, JW | 1 |
| Ogino, T | 1 |
| Avison, M | 1 |
| Alger, JR | 1 |
| Shulman, RG | 1 |
| Swan, JH | 1 |
| Meldrum, BS | 1 |
| Folbegrova, J | 1 |
| Siesjö, BK | 1 |
| Fripp, RR | 1 |
| Yagel, SK | 1 |
| Werner, JC | 1 |
| McGrath, G | 1 |
| Schuler, HG | 1 |
| Johansson, BB | 1 |
| Fredriksson, K | 1 |
25 other studies available for lactic acid and Absence Status
| Article | Year |
|---|---|
Time dependency of CSF cell count, lactate and blood-CSF barrier dysfunction after epileptic seizures and status epilepticus.
Topics: Cell Count; Epilepsy; Humans; Lactic Acid; Seizures; Status Epilepticus | 2022 |
Glycolytic lactate production supports status epilepticus in experimental animals.
Topics: Animals; Glucose; Glycolysis; Humans; Lactic Acid; Mice; Pyruvates; Seizures; Status Epilepticus | 2023 |
Development and validation of a peripheral cell ratio and lactate score for differentiating status epilepticus from prolonged psychogenic nonepileptic seizures.
Topics: Humans; Lactic Acid; Leukocyte Count; Psychogenic Nonepileptic Seizures; Retrospective Studies; Stat | 2023 |
Amperometric bio-sensing of lactate and oxygen concurrently with local field potentials during status epilepticus.
Topics: 4-Aminopyridine; Animals; Biosensing Techniques; Brain; Epilepsy; Humans; Lactic Acid; Oxygen; Rats; | 2024 |
Microdialysis Findings in a Patient with New Onset Refractory Non-convulsive Status Epilepticus.
Topics: Anticonvulsants; Electroencephalography; Female; Frontal Lobe; Glucose; Glutamic Acid; Humans; Immun | 2020 |
Cerebrospinal fluid lactate concentrations in dogs with seizure disorders.
Topics: Animals; Dog Diseases; Dogs; Epilepsy; Humans; Lactic Acid; Seizures; Status Epilepticus | 2020 |
Effect of Training at Lactate Threshold Intensity on Maximal Time to Exhaustion, Depression and Anxiety Behaviour of Spontaneously Hypertensive Rats after Kainate-Induced Status Epilepticus.
Topics: Animals; Anxiety; Behavior, Animal; Comorbidity; Depression; Disease Models, Animal; Essential Hyper | 2017 |
Effect of epileptic seizures on the cerebrospinal fluid--A systematic retrospective analysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Albumins; Cell Count; Cerebrospinal Fluid; Epilepsy; Fem | 2015 |
Early metabolic responses to lithium/pilocarpine-induced status epilepticus in rat brain.
Topics: Animals; Brain; Choline; Convulsants; Disease Models, Animal; Electrochemistry; Electron Transport C | 2015 |
Intravenous levetiracetam terminates refractory status epilepticus in two patients with migrating partial seizures in infancy.
Topics: Ammonia; Anticonvulsants; Blood Cell Count; Creatine; Drug Administration Schedule; Electroencephalo | 2009 |
In vivo glutamate decline associated with kainic acid-induced status epilepticus.
Topics: Analysis of Variance; Animals; Aspartic Acid; Disease Progression; Glutamic Acid; Hippocampus; Image | 2009 |
Brain metabolism and diffusion in the rat cerebral cortex during pilocarpine-induced status epilepticus.
Topics: Animals; Body Water; Brain Chemistry; Cerebral Cortex; Diffusion Magnetic Resonance Imaging; Electro | 2008 |
Nonconvulsive electrographic seizures after traumatic brain injury result in a delayed, prolonged increase in intracranial pressure and metabolic crisis.
Topics: Case-Control Studies; Electroencephalography; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy, | 2007 |
Immunohistochemical studies with antibodies to neurofilament proteins on axonal damage in experimental focal lesions in rat.
Topics: Animals; Axons; Biomarkers; Brain Injuries; Cerebral Infarction; Immunoenzyme Techniques; Lactates; | 1993 |
MR spectroscopic imaging and diffusion-weighted MRI for early detection of kainate-induced status epilepticus in the rat.
Topics: Animals; Aspartic Acid; Blood Gas Analysis; Brain; Excitatory Amino Acid Agonists; Hydrogen-Ion Conc | 1996 |
Correlation between hypermetabolism and neuronal damage during status epilepticus induced by lithium and pilocarpine in immature and adult rats.
Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Brain; Glucose; Lactic Acid; Lithium; Male; Nerv | 1999 |
Similar increases in extracellular lactic acid in the limbic system during epileptic and/or olfactory stimulation.
Topics: 2-Amino-5-phosphonovalerate; Animals; Convulsants; Denervation; Dose-Response Relationship, Drug; Ep | 2000 |
Respiratory chain deficiency in Alpers syndrome.
Topics: Atrophy; Biopsy, Needle; Cerebral Cortex; Child, Preschool; Consanguinity; Diagnosis, Differential; | 2001 |
Brain energy state and lactate metabolism during status epilepticus in the neonatal dog: in vivo 31P and 1H nuclear magnetic resonance study.
Topics: Adenine Nucleotides; Amino Acids; Animals; Animals, Newborn; Brain; Dogs; Energy Metabolism; Fluroth | 1991 |
Brain phenobarbital uptake during prolonged status epilepticus.
Topics: Animals; Bicuculline; Blood; Blood Pressure; Blood-Brain Barrier; Brain; Cerebrovascular Circulation | 1987 |
Combined 1H and 31P nuclear magnetic resonance spectroscopic studies of bicuculline-induced seizures in vivo.
Topics: Animals; Bicuculline; Blood Pressure; Electroencephalography; Female; Heart Rate; Hydrogen; Hydrogen | 1986 |
Hyperglycemia does not augment neuronal damage in experimental status epilepticus.
Topics: Animals; Brain; Glucose; Hyperglycemia; Lactates; Lactic Acid; Male; Neurons; Rats; Rats, Inbred Str | 1986 |
Metabolic alterations underlying the development of hypermetabolic necrosis in the substantia nigra in status epilepticus.
Topics: Adenosine Triphosphate; Animals; Glucose; Glycogen; Lactates; Lactic Acid; Necrosis; Periaqueductal | 1987 |
Cardiac dysfunction during status epilepticus in the neonatal pig.
Topics: Acid-Base Equilibrium; Animals; Animals, Newborn; Bicuculline; Blood Glucose; Blood Pressure; Cardia | 1985 |
Cerebral energy metabolism during bicuculline-induced status epilepticus in spontaneously hypertensive rats.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Bicuculline; Brain; Cerebrovascular Circulat | 1985 |