lactic acid has been researched along with Abnormalities, Sex Chromosome in 2 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The majority of patients with PDHC deficiency have abnormalities in the major catalytic and regulatory subunit, E1 alpha, which is encoded on the X chromosome." | 1.29 | Cerebral dysgenesis and lactic acidemia: an MRI/MRS phenotype associated with pyruvate dehydrogenase deficiency. ( Arnold, DL; Brown, GK; Brown, RM; Legris, M; Matthews, PM; Otero, LJ; Scriver, CR; Shevell, MI, 1994) |
| "Despite regional variability of demyelination, proton magnetic resonance spectroscopy revealed a specific metabolic pattern in all patients, with only moderate reduction of N-acetylaspartate, normal or reduced choline-containing compounds, normal or enhanced myo-inositol and no detectable lactate, which differs from findings in progressive cerebral adrenoleukodystrophy which usually exhibits a severe reduction of N-acetylaspartate and marked increases of choline-containing compounds, myo-inositol, and lactate." | 1.29 | Arrested cerebral adrenoleukodystrophy: a clinical and proton magnetic resonance spectroscopy study in three patients. ( Frahm, J; Hanefeld, F; Hunneman, DH; Jost, W; Korenke, GC; Krasemann, E; Pouwels, PJ; Stoeckler, S, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shevell, MI | 1 |
| Matthews, PM | 1 |
| Scriver, CR | 1 |
| Brown, RM | 1 |
| Otero, LJ | 1 |
| Legris, M | 1 |
| Brown, GK | 1 |
| Arnold, DL | 1 |
| Korenke, GC | 1 |
| Pouwels, PJ | 1 |
| Frahm, J | 1 |
| Hunneman, DH | 1 |
| Stoeckler, S | 1 |
| Krasemann, E | 1 |
| Jost, W | 1 |
| Hanefeld, F | 1 |
2 other studies available for lactic acid and Abnormalities, Sex Chromosome
| Article | Year |
|---|---|
Cerebral dysgenesis and lactic acidemia: an MRI/MRS phenotype associated with pyruvate dehydrogenase deficiency.
Topics: Acidosis, Lactic; Agenesis of Corpus Callosum; Brain; Brain Damage, Chronic; Brain Diseases, Metabol | 1994 |
Arrested cerebral adrenoleukodystrophy: a clinical and proton magnetic resonance spectroscopy study in three patients.
Topics: Aspartic Acid; Brain; Brain Diseases, Metabolic; Child; Choline; Demyelinating Diseases; Female; Hum | 1996 |