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labetalol and Ventricular Fibrillation

labetalol has been researched along with Ventricular Fibrillation in 5 studies

Labetalol: A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.
labetalol : A diastereoisomeric mixture of approximately equal amounts of all four possible stereoisomers ((R,S)-labetolol, (S,R)-labetolol, (S,S)-labetalol and (R,R)-labetalol). It is an adrenergic antagonist used to treat high blood pressure.
2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide : A member of the class of benzamides that is benzamide substituted by a hydroxy group at position 2 and by a 1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl group at position 5.

Ventricular Fibrillation: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.

Research Excerpts

ExcerptRelevanceReference
"The antiarrhythmic and antifibrillatory actions of dilevalol, the R,R-isomer of labetalol, were evaluated in conscious dogs 4 to 6 days after anterior myocardial infarction."3.67Antifibrillatory efficacy of concomitant beta adrenergic receptor blockade with dilevalol, the R,R-isomer of labetalol, and muscarinic receptor blockade with methylscopolamine. ( Driscoll, EM; Lucchesi, BR; Lynch, JJ; MacEwen, SA; Nelson, SD, 1987)
"Patients in cardiac arrest are often taking medications affecting adrenergic activity such as the beta blocker metoprolol and the combined alpha and beta blocker, labetalol."1.38Beta-blockade causes a reduction in the frequency spectrum of VF but improves resuscitation outcome: A potential limitation of quantitative waveform measures. ( Niemann, J; Rosborough, JP; Shah, AP; Sherman, L; Youngquist, ST, 2012)
"Moxonidine has been shown to be antiarrhythmic during ischaemia in vivo."1.30Facilitation of spontaneous defibrillation by moxonidine during regional ischaemia in an isolated working rabbit heart model. ( Cobbe, SM; Hicks, MN; Kane, KA; Wolk, R, 1999)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sherman, L1
Niemann, J1
Youngquist, ST1
Shah, AP1
Rosborough, JP1
Krug, H1
Poprawski, K1
Ochotny, R1
Wolk, R1
Kane, KA1
Cobbe, SM1
Hicks, MN1
Fitzgerald, JD1
Lynch, JJ1
Nelson, SD1
MacEwen, SA1
Driscoll, EM1
Lucchesi, BR1

Reviews

1 review available for labetalol and Ventricular Fibrillation

ArticleYear
The possible role of the ancillary properties of beta adrenoceptor antagonists in the management of angina pectoris.
    Acta medica Scandinavica. Supplementum, 1985, Volume: 694

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angina Pectoris; Animals; Anxiety Disorde

1985

Other Studies

4 other studies available for labetalol and Ventricular Fibrillation

ArticleYear
Beta-blockade causes a reduction in the frequency spectrum of VF but improves resuscitation outcome: A potential limitation of quantitative waveform measures.
    Resuscitation, 2012, Volume: 83, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Cardiopulmonary Resuscitation; Confidence Intervals; Disease M

2012
[Vasospastic angina pectoris complicated by ventricular fibrillation during treatment with propranolol and labetalol].
    Kardiologia polska, 1983, Volume: 26, Issue:1

    Topics: Angina Pectoris, Variant; Coronary Disease; Coronary Vasospasm; Ethanolamines; Female; Humans; Labet

1983
Facilitation of spontaneous defibrillation by moxonidine during regional ischaemia in an isolated working rabbit heart model.
    European journal of pharmacology, 1999, Feb-12, Volume: 367, Issue:1

    Topics: Action Potentials; Animals; Antihypertensive Agents; Arrhythmias, Cardiac; Disease Models, Animal; E

1999
Antifibrillatory efficacy of concomitant beta adrenergic receptor blockade with dilevalol, the R,R-isomer of labetalol, and muscarinic receptor blockade with methylscopolamine.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Dogs; Electrocar

1987