Page last updated: 2024-10-30

labetalol and Tachycardia

labetalol has been researched along with Tachycardia in 28 studies

Labetalol: A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.
labetalol : A diastereoisomeric mixture of approximately equal amounts of all four possible stereoisomers ((R,S)-labetolol, (S,R)-labetolol, (S,S)-labetalol and (R,R)-labetalol). It is an adrenergic antagonist used to treat high blood pressure.
2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide : A member of the class of benzamides that is benzamide substituted by a hydroxy group at position 2 and by a 1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl group at position 5.

Tachycardia: Abnormally rapid heartbeat, usually with a HEART RATE above 100 beats per minute for adults. Tachycardia accompanied by disturbance in the cardiac depolarization (cardiac arrhythmia) is called tachyarrhythmia.

Research Excerpts

ExcerptRelevanceReference
"We compared the efficacy of the combination of enalaprilat/labetalol with that of enalaprilat/nicardipine to prevent emergence postcraniotomy hypertension."9.09A comparative study between a calcium channel blocker (Nicardipine) and a combined alpha-beta-blocker (Labetalol) for the control of emergence hypertension during craniotomy for tumor surgery. ( Broad, C; Ferri, E; Kross, RA; Leung, D; Melendez, JA; Pratila, M; Veronesi, M, 2000)
"The antihypertensive efficacy and safety of IV labetalol were evaluated and compared with the efficacy and safety of IV hydralazine in the treatment of postoperative hypertension."9.06Comparative hemodynamic effects of labetalol and hydralazine in the treatment of postoperative hypertension. ( Dimich, I; Gabrielson, G; Kaplan, JA; Lingham, R; Singh, PP, 1989)
"Topical cocaine is sometimes used for the treatment of epistaxis, as it has both potent anesthetic and vasoconstrictive properties."7.85Acute Toxicity from Topical Cocaine for Epistaxis: Treatment with Labetalol. ( Lange, RA; Laurin, EG; Richards, JR; Tabish, N, 2017)
"On the 3rd day after a cesarean section, because of pre-eclampsia, blood pressure was still high, oral labetalol 100 mg with an 8-hour interval was given, followed by 50 mg i."7.68Hemodynamic collapse following labetalol administration in preeclampsia. ( Beier-Holgersen, R; Olsen, KS, 1992)
" doses of labetalol were evaluated in 10 normovolaemic sedated patients presenting with hypertension and tachycardia in the early period after myocardial revascularization."7.66I.v. labetalol in the treatment of hypertension following coronary-artery surgery. ( Forster, A; Morel, DR; Suter, PM, 1982)
"Twenty-five women with preeclampsia who were scheduled to undergo cesarean section under general anesthesia were randomly assigned to either a labetalol pretreatment group (n = 15) or a control group (n = 10) who did not receive any antihypertensive therapy before the induction of anesthesia."6.66The use of labetalol for attenuation of the hypertensive response to endotracheal intubation in preeclampsia. ( Chauhan, D; Mabie, WC; Ramanathan, J; Ruiz, AG; Sibai, BM, 1988)
"Fetal tachycardia was present as well."5.30Intrapartum labetalol for the treatment of maternal and fetal thyrotoxicosis. ( Bergmann, M; Bowman, ML; Smith, JF, 1998)
"We compared the efficacy of the combination of enalaprilat/labetalol with that of enalaprilat/nicardipine to prevent emergence postcraniotomy hypertension."5.09A comparative study between a calcium channel blocker (Nicardipine) and a combined alpha-beta-blocker (Labetalol) for the control of emergence hypertension during craniotomy for tumor surgery. ( Broad, C; Ferri, E; Kross, RA; Leung, D; Melendez, JA; Pratila, M; Veronesi, M, 2000)
"Labetalol, a drug with alpha- and beta-adrenergic receptor blocking effects, was used to attenuate hypertension and tachycardia associated with electroconvulsive therapy (ECT) in a series of 11 elderly patients with refractory depression and cardiovascular disease in a placebo-controlled, double-blind crossover study design."5.06Labetalol in the control of cardiovascular responses to electroconvulsive therapy in high-risk depressed medical patients. ( Cooper, R; Gladson, M; Knos, G; Markwalter, H; Morris, R; Stoudemire, A; Sung, YF, 1990)
"The antihypertensive efficacy and safety of IV labetalol were evaluated and compared with the efficacy and safety of IV hydralazine in the treatment of postoperative hypertension."5.06Comparative hemodynamic effects of labetalol and hydralazine in the treatment of postoperative hypertension. ( Dimich, I; Gabrielson, G; Kaplan, JA; Lingham, R; Singh, PP, 1989)
"The present evidence suggests similar efficacy between nifedipine, hydralazine and labetalol in the treatment of severe hypertension in pregnancy."4.98Drugs for treating severe hypertension in pregnancy: a network meta-analysis and trial sequential analysis of randomized clinical trials. ( Sequeira, RP; Sridharan, K, 2018)
"Topical cocaine is sometimes used for the treatment of epistaxis, as it has both potent anesthetic and vasoconstrictive properties."3.85Acute Toxicity from Topical Cocaine for Epistaxis: Treatment with Labetalol. ( Lange, RA; Laurin, EG; Richards, JR; Tabish, N, 2017)
"Preoperative alpha- and beta-adrenergic receptor block with phenoxybenzamine and labetalol, the intraoperative course of a 4-month-old infant with neuroblastoma and elevated catecholamines causing sweating, hypertension, and tachycardia, are presented."3.75Catecholamine-secreting neuroblastoma in a 4-month-old infant: perioperative management. ( Hernandez, MR; Seefelder, C; Shamberger, RC, 2009)
"On the 3rd day after a cesarean section, because of pre-eclampsia, blood pressure was still high, oral labetalol 100 mg with an 8-hour interval was given, followed by 50 mg i."3.68Hemodynamic collapse following labetalol administration in preeclampsia. ( Beier-Holgersen, R; Olsen, KS, 1992)
" doses of labetalol were evaluated in 10 normovolaemic sedated patients presenting with hypertension and tachycardia in the early period after myocardial revascularization."3.66I.v. labetalol in the treatment of hypertension following coronary-artery surgery. ( Forster, A; Morel, DR; Suter, PM, 1982)
"Hypertension and tachycardia are common during fiber-optic bronchoscopy (FOB), and this may lead to cardiac ischemia."2.73Benzodiazepine and opioid sedation attenuate the sympathetic response to fiberoptic bronchoscopy. Prophylactic labetalol gave no additional benefit. Results of a randomized double-blind placebo-controlled study. ( Ben-Zvi, I; Fox, BD; Kramer, MR; Krylov, Y; Leon, P; Peled, N; Shitrit, D, 2008)
"Twenty-five women with preeclampsia who were scheduled to undergo cesarean section under general anesthesia were randomly assigned to either a labetalol pretreatment group (n = 15) or a control group (n = 10) who did not receive any antihypertensive therapy before the induction of anesthesia."2.66The use of labetalol for attenuation of the hypertensive response to endotracheal intubation in preeclampsia. ( Chauhan, D; Mabie, WC; Ramanathan, J; Ruiz, AG; Sibai, BM, 1988)
"Fetal tachycardia was present as well."1.30Intrapartum labetalol for the treatment of maternal and fetal thyrotoxicosis. ( Bergmann, M; Bowman, ML; Smith, JF, 1998)
"Nicardipine was given by slow intravenous injection."1.27Baroreflex sensitivity alteration following transient hemispheric ischaemia in rats: protective effect of alphamethyldopa and guanfacine. ( Elghozi, JL; Meyer, P; Saad, MA, 1986)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199010 (35.71)18.7374
1990's8 (28.57)18.2507
2000's6 (21.43)29.6817
2010's3 (10.71)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Ou, HC1
Deng, JF1
Yang, CC1
Lin, CS1
Mao, YC1
Tsai, SH1
Ho, CH1
Sridharan, K1
Sequeira, RP1
Richards, JR2
Laurin, EG1
Tabish, N1
Lange, RA2
Arnold, TC1
Horowitz, BZ1
Hernandez, MR1
Shamberger, RC1
Seefelder, C1
Asencio Moreno, A1
Alamán Orbañanos, B1
Moro Velasco, MC1
Diamond, AL1
Callison, RC1
Shokri, J1
Cruz-Flores, S1
Kinsella, LJ1
Fox, BD1
Krylov, Y1
Leon, P1
Ben-Zvi, I1
Peled, N1
Shitrit, D1
Kramer, MR1
Domenighetti, GM1
Savary, G1
Stricker, H1
Morel, DR1
Forster, A1
Suter, PM1
Stoudemire, A2
Drop, L1
Castelli, I1
Kaufmann, M1
Bowman, ML1
Bergmann, M1
Smith, JF1
Pittman, JA1
Kross, RA1
Ferri, E1
Leung, D1
Pratila, M1
Broad, C1
Veronesi, M1
Melendez, JA1
Fagard, R1
Amery, A1
Reybrouck, T1
Lijnen, P1
Billiet, L1
Olsen, KS1
Beier-Holgersen, R1
Etzel, R1
Knos, G1
Gladson, M1
Markwalter, H1
Sung, YF1
Morris, R1
Cooper, R1
Goldsmith, TL1
Barker, DE1
Strodel, WE1
Higgins, TL1
Estafanous, FG1
Leslie, JB1
Kalayjian, RW1
McLoughlin, TM1
Plachetka, JR1
Dimich, I1
Lingham, R1
Gabrielson, G1
Singh, PP1
Kaplan, JA1
Inada, E1
Cullen, DJ1
Nemeskal, AR1
Teplick, R1
Saad, MA1
Elghozi, JL1
Meyer, P1
Harrier, HD1
Ramanathan, J1
Sibai, BM1
Mabie, WC1
Chauhan, D1
Ruiz, AG1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Safety and Efficacy of Sedation for Flexible Fiberoptic Bronchoscopy: Comparison of Propofol/Alfentanil With Propofol/Ketamine[NCT02000206]80 participants (Anticipated)Interventional2014-02-28Not yet recruiting
[NCT00394537]Phase 472 participants (Anticipated)InterventionalCompleted
Efficiency of Intravenous Lidocaine to Reduce Coughing and the Hemodynamic Changes Associated to Tracheal Extubation[NCT03731429]Phase 4144 participants (Anticipated)Interventional2019-04-05Recruiting
Nicardipine Versus Esmolol for Management of Emergence Hypertension After Craniotomy[NCT01951950]Phase 140 participants (Actual)Interventional2013-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Failure of Drug to Control Systolic Blood Pressure (SBP) < 140 mmHg

(NCT01951950)
Timeframe: 1 hour postoperatively

Interventionparticipants (Number)
Nicardipine1
Esmolol11

Reviews

1 review available for labetalol and Tachycardia

ArticleYear
Drugs for treating severe hypertension in pregnancy: a network meta-analysis and trial sequential analysis of randomized clinical trials.
    British journal of clinical pharmacology, 2018, Volume: 84, Issue:9

    Topics: Antihypertensive Agents; Dose-Response Relationship, Drug; Female; Headache; Humans; Hydralazine; Hy

2018

Trials

7 trials available for labetalol and Tachycardia

ArticleYear
Benzodiazepine and opioid sedation attenuate the sympathetic response to fiberoptic bronchoscopy. Prophylactic labetalol gave no additional benefit. Results of a randomized double-blind placebo-controlled study.
    Respiratory medicine, 2008, Volume: 102, Issue:7

    Topics: Adrenergic beta-Antagonists; Alfentanil; Analgesics, Opioid; Antihypertensive Agents; Benzodiazepine

2008
Benzodiazepine and opioid sedation attenuate the sympathetic response to fiberoptic bronchoscopy. Prophylactic labetalol gave no additional benefit. Results of a randomized double-blind placebo-controlled study.
    Respiratory medicine, 2008, Volume: 102, Issue:7

    Topics: Adrenergic beta-Antagonists; Alfentanil; Analgesics, Opioid; Antihypertensive Agents; Benzodiazepine

2008
Benzodiazepine and opioid sedation attenuate the sympathetic response to fiberoptic bronchoscopy. Prophylactic labetalol gave no additional benefit. Results of a randomized double-blind placebo-controlled study.
    Respiratory medicine, 2008, Volume: 102, Issue:7

    Topics: Adrenergic beta-Antagonists; Alfentanil; Analgesics, Opioid; Antihypertensive Agents; Benzodiazepine

2008
Benzodiazepine and opioid sedation attenuate the sympathetic response to fiberoptic bronchoscopy. Prophylactic labetalol gave no additional benefit. Results of a randomized double-blind placebo-controlled study.
    Respiratory medicine, 2008, Volume: 102, Issue:7

    Topics: Adrenergic beta-Antagonists; Alfentanil; Analgesics, Opioid; Antihypertensive Agents; Benzodiazepine

2008
A comparative study between a calcium channel blocker (Nicardipine) and a combined alpha-beta-blocker (Labetalol) for the control of emergence hypertension during craniotomy for tumor surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Anesth

2000
A comparative study between a calcium channel blocker (Nicardipine) and a combined alpha-beta-blocker (Labetalol) for the control of emergence hypertension during craniotomy for tumor surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Anesth

2000
A comparative study between a calcium channel blocker (Nicardipine) and a combined alpha-beta-blocker (Labetalol) for the control of emergence hypertension during craniotomy for tumor surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Anesth

2000
A comparative study between a calcium channel blocker (Nicardipine) and a combined alpha-beta-blocker (Labetalol) for the control of emergence hypertension during craniotomy for tumor surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Anesth

2000
Labetalol in the control of cardiovascular responses to electroconvulsive therapy in high-risk depressed medical patients.
    The Journal of clinical psychiatry, 1990, Volume: 51, Issue:12

    Topics: Aged; Arrhythmias, Cardiac; Blood Pressure; Cardiovascular Diseases; Depressive Disorder; Double-Bli

1990
Attenuation of the hemodynamic responses to endotracheal intubation with preinduction intravenous labetalol.
    Journal of clinical anesthesia, 1989, Volume: 1, Issue:3

    Topics: Adult; Female; Humans; Hypertension; Infusions, Intravenous; Intubation, Intratracheal; Labetalol; M

1989
Comparative hemodynamic effects of labetalol and hydralazine in the treatment of postoperative hypertension.
    Journal of clinical anesthesia, 1989, Volume: 1, Issue:3

    Topics: Aged; Female; Hemodynamics; Humans; Hydralazine; Hypertension; Labetalol; Male; Middle Aged; Postope

1989
Effect of labetalol or lidocaine on the hemodynamic response to intubation: a controlled randomized double-blind study.
    Journal of clinical anesthesia, 1989, Volume: 1, Issue:3

    Topics: Adult; Aged; Analysis of Variance; Blood Pressure; Double-Blind Method; Female; Heart Rate; Humans;

1989
The use of labetalol for attenuation of the hypertensive response to endotracheal intubation in preeclampsia.
    American journal of obstetrics and gynecology, 1988, Volume: 159, Issue:3

    Topics: Adolescent; Adult; Anesthesia, Obstetrical; Blood Pressure; Cesarean Section; Female; Humans; Hypert

1988

Other Studies

20 other studies available for labetalol and Tachycardia

ArticleYear
A successful experience using labetalol and hemodialysis to treat near-fatal caffeine poisoning: A case report with toxicodynamics.
    The American journal of emergency medicine, 2022, Volume: 55

    Topics: Adolescent; Caffeine; Central Nervous System Stimulants; Humans; Labetalol; Male; Renal Dialysis; Su

2022
Acute Toxicity from Topical Cocaine for Epistaxis: Treatment with Labetalol.
    The Journal of emergency medicine, 2017, Volume: 52, Issue:3

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Analgesics; Cocaine; Emergency Service, Hospit

2017
Dual cocaine and methamphetamine cardiovascular toxicity: rapid resolution with labetalol.
    The American journal of emergency medicine, 2017, Volume: 35, Issue:3

    Topics: Administration, Intravenous; Adrenergic beta-Antagonists; Amphetamine-Related Disorders; Anti-Anxiet

2017
Catecholamine-secreting neuroblastoma in a 4-month-old infant: perioperative management.
    Journal of clinical anesthesia, 2009, Volume: 21, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Catecholamines; Female; Humans; Hypertens

2009
[Anesthesia for the surgical removal of bilateral pheochromocytomas during the second trimester of pregnancy].
    Revista espanola de anestesiologia y reanimacion, 2009, Volume: 56, Issue:1

    Topics: Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Adult; Anesthesia, Epidural; Anesthesia, Gene

2009
Paroxysmal sympathetic storm.
    Neurocritical care, 2005, Volume: 2, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Analgesics, Opioid; Brain Injuries; Fever; Heart Arrest; Humans;

2005
Hyperadrenergic syndrome in severe tetanus: extreme rise in catecholamines responsive to labetalol.
    British medical journal (Clinical research ed.), 1984, May-19, Volume: 288, Issue:6429

    Topics: Adrenergic Fibers; Aged; Catecholamines; Ethanolamines; Humans; Hypertension; Labetalol; Male; Nervo

1984
I.v. labetalol in the treatment of hypertension following coronary-artery surgery.
    British journal of anaesthesia, 1982, Volume: 54, Issue:11

    Topics: Aged; Blood Pressure; Ethanolamines; Heart Rate; Humans; Hypertension; Injections, Intravenous; Labe

1982
Cardiovascular complications of ECT.
    The American journal of psychiatry, 1994, Volume: 151, Issue:5

    Topics: Cardiovascular Diseases; Depressive Disorder; Electroconvulsive Therapy; Humans; Hypertension; Labet

1994
Comparative doses and cost: esmolol versus labetalol during electroconvulsive therapy.
    Anesthesia and analgesia, 1998, Volume: 86, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Blood Pressure; Cost Savings; Drug Cost

1998
Intrapartum labetalol for the treatment of maternal and fetal thyrotoxicosis.
    Thyroid : official journal of the American Thyroid Association, 1998, Volume: 8, Issue:9

    Topics: Adolescent; Female; Fetal Diseases; Heart Rate, Fetal; Humans; Hypertension; Infant, Newborn; Infant

1998
Magnesium sulphate for pre-eclampsia and a sudden bradycardia.
    British journal of anaesthesia, 2000, Volume: 85, Issue:2

    Topics: Adolescent; Adrenergic beta-Antagonists; Bradycardia; Calcium Channel Blockers; Drug Interactions; F

2000
Response of the systemic and pulmonary circulation to alpha- and beta-receptor blockade (labetalol) at rest and during exercise in hypertensive patients.
    Circulation, 1979, Volume: 60, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Blood Circulation; Blood Pressure;

1979
Hemodynamic collapse following labetalol administration in preeclampsia.
    Acta obstetricia et gynecologica Scandinavica, 1992, Volume: 71, Issue:2

    Topics: Adult; Cesarean Section; Female; Humans; Hypotension; Labetalol; Pre-Eclampsia; Pregnancy; Premedica

1992
"Cardiovascular effects of cocaine".
    The Journal of cardiovascular nursing, 1992, Volume: 7, Issue:1

    Topics: Cocaine; Humans; Hypertension; Labetalol; Tachycardia

1992
Labetalol and ECT.
    The Journal of clinical psychiatry, 1991, Volume: 52, Issue:9

    Topics: Age Factors; Aged; Coronary Disease; Depressive Disorder; Electroconvulsive Therapy; Humans; Hyperte

1991
Prolonged labetalol infusion for management of severe hypertension and tachycardia in a critically ill trauma patient.
    DICP : the annals of pharmacotherapy, 1990, Volume: 24, Issue:3

    Topics: Adult; Blood Pressure; Critical Care; Heart Rate; Humans; Hypertension; Infusions, Intravenous; Labe

1990
Labetalol: time, experience, and adrenergic blockade.
    Journal of clinical anesthesia, 1989, Volume: 1, Issue:3

    Topics: Coronary Disease; Humans; Hypertension; Intubation, Intratracheal; Labetalol; Postoperative Complica

1989
Baroreflex sensitivity alteration following transient hemispheric ischaemia in rats: protective effect of alphamethyldopa and guanfacine.
    Clinical and experimental pharmacology & physiology, 1986, Volume: 13, Issue:7

    Topics: Animals; Blood Pressure; Enalapril; Guanfacine; Guanidines; Heart Rate; Ischemic Attack, Transient;

1986
Use of labetalol in trauma.
    Critical care medicine, 1988, Volume: 16, Issue:11

    Topics: Adolescent; Adult; Craniocerebral Trauma; Female; Hemodynamics; Humans; Hypertension; Labetalol; Mal

1988