labetalol has been researched along with Subarachnoid Hemorrhage in 8 studies
Labetalol: A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.
labetalol : A diastereoisomeric mixture of approximately equal amounts of all four possible stereoisomers ((R,S)-labetolol, (S,R)-labetolol, (S,S)-labetalol and (R,R)-labetalol). It is an adrenergic antagonist used to treat high blood pressure.
2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide : A member of the class of benzamides that is benzamide substituted by a hydroxy group at position 2 and by a 1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl group at position 5.
Subarachnoid Hemorrhage: Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nicardipine and labetalol are two commonly used antihypertensives for treating elevated blood pressures in the setting of intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH)." | 7.79 | Effectiveness and safety of nicardipine and labetalol infusion for blood pressure management in patients with intracerebral and subarachnoid hemorrhage. ( Agarwal, S; Badjatia, N; Carpenter, AM; Claassen, J; Lantigua, H; Lee, K; Lesch, C; Li, M; Mayer, SA; Ortega-Gutierrez, S; Reccius, A; Schmidt, JM; Thomas, J, 2013) |
| "American Heart Association/American Stroke Association guidelines for management of aneurysmal subarachnoid hemorrhage (aSAH) recommend blood pressure (BP) control, utilizing labetalol or nicardipine, but do not differentiate efficacy between the two agents." | 7.78 | Retrospective evaluation of nicardipine versus labetalol for blood pressure control in aneurysmal subarachnoid hemorrhage. ( Barletta, JF; DeShane, RS; Figueroa, BE; McAllen, KJ; Woloszyn, AV, 2012) |
| "The episode of profound hypotension which occurred after initiating a labetolol infusion required maximal combined vasopressor therapy to restore the blood pressure suggesting that this patient demonstrated an extreme sensitivity to labetalol." | 7.73 | Case report: profound hypotension associated with labetalol therapy in a patient with cerebral aneurysms and subarachnoid hemorrhage. ( Baker, AJ; Choi, M; Hare, GM; Jivraj, S; Mazer, CD, 2006) |
| "Nicardipine and labetalol are two commonly used antihypertensives for treating elevated blood pressures in the setting of intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH)." | 3.79 | Effectiveness and safety of nicardipine and labetalol infusion for blood pressure management in patients with intracerebral and subarachnoid hemorrhage. ( Agarwal, S; Badjatia, N; Carpenter, AM; Claassen, J; Lantigua, H; Lee, K; Lesch, C; Li, M; Mayer, SA; Ortega-Gutierrez, S; Reccius, A; Schmidt, JM; Thomas, J, 2013) |
| "American Heart Association/American Stroke Association guidelines for management of aneurysmal subarachnoid hemorrhage (aSAH) recommend blood pressure (BP) control, utilizing labetalol or nicardipine, but do not differentiate efficacy between the two agents." | 3.78 | Retrospective evaluation of nicardipine versus labetalol for blood pressure control in aneurysmal subarachnoid hemorrhage. ( Barletta, JF; DeShane, RS; Figueroa, BE; McAllen, KJ; Woloszyn, AV, 2012) |
| "The episode of profound hypotension which occurred after initiating a labetolol infusion required maximal combined vasopressor therapy to restore the blood pressure suggesting that this patient demonstrated an extreme sensitivity to labetalol." | 3.73 | Case report: profound hypotension associated with labetalol therapy in a patient with cerebral aneurysms and subarachnoid hemorrhage. ( Baker, AJ; Choi, M; Hare, GM; Jivraj, S; Mazer, CD, 2006) |
| "In the case of hypertensive encephalopathy, the lowering of blood pressure is therapeutic as well as diagnostic." | 2.43 | [Antihypertensive management in acute cerebral stroke]. ( Ziliene, V, 2005) |
| "This was manifested clinically by a seizure which began focally and became generalised." | 1.30 | Autonomic instability and hypertension resulting in subarachnoid haemorrhage in the Guillain-Barré syndrome. ( Gande, AR; Nolan, KM; Taylor, IR, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Woloszyn, AV | 1 |
| McAllen, KJ | 1 |
| Figueroa, BE | 1 |
| DeShane, RS | 1 |
| Barletta, JF | 1 |
| Ortega-Gutierrez, S | 1 |
| Thomas, J | 1 |
| Reccius, A | 1 |
| Agarwal, S | 1 |
| Lantigua, H | 1 |
| Li, M | 1 |
| Carpenter, AM | 1 |
| Mayer, SA | 2 |
| Schmidt, JM | 1 |
| Lee, K | 1 |
| Claassen, J | 1 |
| Badjatia, N | 1 |
| Lesch, C | 1 |
| Ziliene, V | 1 |
| Jivraj, S | 1 |
| Mazer, CD | 1 |
| Baker, AJ | 1 |
| Choi, M | 1 |
| Hare, GM | 1 |
| Mocco, J | 1 |
| Rose, JC | 1 |
| Komotar, RJ | 1 |
| Patel, RV | 1 |
| Kertland, HR | 1 |
| Jahns, BE | 1 |
| Zarowitz, BJ | 1 |
| Mlynarek, ME | 1 |
| Fagan, SC | 1 |
| Gande, AR | 1 |
| Taylor, IR | 1 |
| Nolan, KM | 1 |
| Pickard, T | 1 |
2 reviews available for labetalol and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
[Antihypertensive management in acute cerebral stroke].
Topics: Acute Disease; Adult; Antihypertensive Agents; Brain Injuries; Cerebrovascular Circulation; Emergenc | 2005 |
Blood pressure management in patients with intracerebral and subarachnoid hemorrhage.
Topics: Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Blood Volume; Brain; Brain Ischemia; E | 2006 |
1 trial available for labetalol and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
Labetalol: response and safety in critically ill hemorrhagic stroke patients.
Topics: Adult; Aged; Blood Pressure; Cerebral Hemorrhage; Cerebrovascular Disorders; Critical Illness; Femal | 1993 |
5 other studies available for labetalol and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
Retrospective evaluation of nicardipine versus labetalol for blood pressure control in aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Critical Care; Female; Humans; Hypertension; L | 2012 |
Effectiveness and safety of nicardipine and labetalol infusion for blood pressure management in patients with intracerebral and subarachnoid hemorrhage.
Topics: Adult; Aged; Antihypertensive Agents; Cerebral Hemorrhage; Cohort Studies; Drug Therapy, Combination | 2013 |
Case report: profound hypotension associated with labetalol therapy in a patient with cerebral aneurysms and subarachnoid hemorrhage.
Topics: Antihypertensive Agents; Bradycardia; Cardiotonic Agents; Dopamine; Epinephrine; Female; Humans; Hyp | 2006 |
Autonomic instability and hypertension resulting in subarachnoid haemorrhage in the Guillain-Barré syndrome.
Topics: Antihypertensive Agents; Autonomic Nervous System Diseases; Diagnosis, Differential; Female; Guillai | 1999 |
Getting past the obvious in an ED case of altered mental status and ECG changes.
Topics: Antihypertensive Agents; Arrhythmias, Cardiac; Diagnosis, Differential; Electrocardiography; Emergen | 2000 |