labetalol has been researched along with Puerperal Disorders in 9 studies
Labetalol: A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.
labetalol : A diastereoisomeric mixture of approximately equal amounts of all four possible stereoisomers ((R,S)-labetolol, (S,R)-labetolol, (S,S)-labetalol and (R,R)-labetalol). It is an adrenergic antagonist used to treat high blood pressure.
2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide : A member of the class of benzamides that is benzamide substituted by a hydroxy group at position 2 and by a 1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl group at position 5.
Puerperal Disorders: Disorders or diseases associated with PUERPERIUM, the six-to-eight-week period immediately after PARTURITION in humans.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether oral labetalol is associated with a shorter time to blood pressure control compared to oral extended release nifedipine for management of persistent postpartum hypertension." | 9.24 | Oral labetalol compared to oral nifedipine for postpartum hypertension: A randomized controlled trial. ( Greene, N; Kilpatrick, SJ; Sharma, KJ, 2017) |
| "To determine whether oral labetalol is associated with a shorter time to blood pressure control compared to oral extended release nifedipine for management of persistent postpartum hypertension." | 5.24 | Oral labetalol compared to oral nifedipine for postpartum hypertension: A randomized controlled trial. ( Greene, N; Kilpatrick, SJ; Sharma, KJ, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sharma, KJ | 2 |
| Kilpatrick, SJ | 2 |
| Lee, R | 1 |
| Carr, D | 1 |
| Greene, N | 1 |
| Santos Nores, J | 1 |
| Bravo López, JJ | 1 |
| Borrajo Prol, MP | 1 |
| Iglesias Forneiro, A | 1 |
| Newbould, S | 1 |
| Stählin, P | 1 |
| Gremmelmaier, D | 1 |
| Verdile, VP | 1 |
| Verdile, LA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Control Trial of Furosemide or Placebo With Usual Antihypertensives in the Antepartum Management of Severe Hypertension With Wide Pulse Pressure[NCT04615624] | Phase 3 | 65 participants (Actual) | Interventional | 2021-01-04 | Completed | ||
| Comparison of Oral Nifedipine to Oral Labetolol for the Management of Severe Postpartum Hypertension[NCT02168309] | 50 participants (Actual) | Interventional | 2014-06-30 | Completed | |||
| Amlodipine Versus Nifedipine ER for the Management of Postpartum Hypertension: A Randomized Controlled Noninferiority Trial[NCT04790279] | Phase 4 | 132 participants (Actual) | Interventional | 2021-04-09 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Primary outcome (NCT02168309)
Timeframe: 24 hours
| Intervention | hours (Mean) |
|---|---|
| Labetalol | 37.6 |
| Nifedipine | 38.2 |
Secondary outcome (NCT02168309)
Timeframe: 0-10 days
| Intervention | days (Mean) |
|---|---|
| Labetalol | 4.0 |
| Nifedipine | 4.3 |
1 review available for labetalol and Puerperal Disorders
| Article | Year |
|---|---|
Postpartum Hypertension: Etiology, Diagnosis, and Management.
Topics: Antihypertensive Agents; Blood Pressure; Disease Management; Female; Humans; Hydralazine; Hypertensi | 2017 |
1 trial available for labetalol and Puerperal Disorders
| Article | Year |
|---|---|
Oral labetalol compared to oral nifedipine for postpartum hypertension: A randomized controlled trial.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Labetalol; Nifedipine; | 2017 |
Oral labetalol compared to oral nifedipine for postpartum hypertension: A randomized controlled trial.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Labetalol; Nifedipine; | 2017 |
Oral labetalol compared to oral nifedipine for postpartum hypertension: A randomized controlled trial.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Labetalol; Nifedipine; | 2017 |
Oral labetalol compared to oral nifedipine for postpartum hypertension: A randomized controlled trial.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Labetalol; Nifedipine; | 2017 |
7 other studies available for labetalol and Puerperal Disorders
| Article | Year |
|---|---|
Committee Opinion No. 692 Summary: Emergent Therapy for Acute-Onset, Severe Hypertension During Pregnancy and the Postpartum Period.
Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Drug Administration Routes; E | 2017 |
Committee Opinion No. 692: Emergent Therapy for Acute-Onset, Severe Hypertension During Pregnancy and the Postpartum Period.
Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Drug Administration Routes; E | 2017 |
Pregnancy-associated spontaneous coronary artery dissection (PASCAD): An etiology for chest pain in the young peripartum patient.
Topics: Adult; Antihypertensive Agents; Aortic Dissection; Chest Pain; Coronary Aneurysm; Electrocardiograph | 2018 |
[HTA-pre-eclampsia-postpartum haemolytic-uraemic syndrome: good results can be achieved].
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Anti-Inflammatory Agents; Antihypertensive Agents; C | 2010 |
Postpartum eclampsia.
Topics: Adult; Anticonvulsants; Antihypertensive Agents; Diagnosis, Differential; Eclampsia; Female; Humans; | 2002 |
[Pregnancy and hypertension].
Topics: Adult; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Cesarean Section; Diagnosis, | 2005 |
Postpartum amaurosis.
Topics: Adult; Blindness; Emergency Service, Hospital; Female; Humans; Labetalol; Magnetic Resonance Imaging | 1991 |