labetalol has been researched along with Proteinuria in 9 studies
Labetalol: A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.
labetalol : A diastereoisomeric mixture of approximately equal amounts of all four possible stereoisomers ((R,S)-labetolol, (S,R)-labetolol, (S,S)-labetalol and (R,R)-labetalol). It is an adrenergic antagonist used to treat high blood pressure.
2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide : A member of the class of benzamides that is benzamide substituted by a hydroxy group at position 2 and by a 1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl group at position 5.
Proteinuria: The presence of proteins in the urine, an indicator of KIDNEY DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A total of 150 consecutive pregnant women without proteinuria and with physician-recorded systolic BP of 140-160 mmHg and/or diastolic BP of 90-105 mmHg on two occasions ≥6 h apart between 20 and 38 weeks of gestation were randomly allocated to receive either labetalol or methyldopa (50 patients each) plus standard care (treatment group) or only standard care (50 patients) (control group)." | 9.16 | Role of antihypertensive therapy in mild to moderate pregnancy-induced hypertension: a prospective randomized study comparing labetalol with alpha methyldopa. ( Jabeen, F; Malik, AR; Mir, S; Molvi, SN; Rana, VS, 2012) |
| "To determine the need for, and efficacy of, treatment with labetalol in women with mild-to-moderate pregnancy induced hypertension (PIH)." | 9.07 | A randomised placebo controlled trial of labetalol in the treatment of mild to moderate pregnancy induced hypertension. ( Broughton Pipkin, F; Pickles, CJ; Symonds, EM, 1992) |
| "The aim of the study was to investigate cord blood leptin concentrations and their relationship to birth weight and gender in term pregnancies complicated by pre-eclampsia." | 7.70 | Serum leptin concentration in cord blood: relationship to birth weight and gender in pregnancies complicated by pre-eclampsia. ( Hartmann, BW; Laml, T; Preyer, O; Ruecklinger, E; Soeregi, G; Wagenbichler, P, 2000) |
| "This study reports the results that were obtained in 56 cases of arterial hypertension in pregnancy solely by beta-blocking with Atenolol or Labetalol." | 7.66 | [Effect of 2 beta-blockers on arterial hypertension during pregnancy. Results of a prospective study on 56 pregnant hypertensive women treated with atenolol and labetalol]. ( Beauséjour, B; Blazquez, G; Faurie, C; Flouvat, B; Gérard, J; Lardoux, H; Rousset, D, 1983) |
| "Labetalol was well tolerated and no significant maternal toxicity was noted." | 6.67 | Does labetalol influence the development of proteinuria in pregnancy hypertension? A randomised controlled study. ( Campbell, DM; Cruickshank, DJ; MacGillivray, I; Robertson, AA, 1992) |
| "A total of 150 consecutive pregnant women without proteinuria and with physician-recorded systolic BP of 140-160 mmHg and/or diastolic BP of 90-105 mmHg on two occasions ≥6 h apart between 20 and 38 weeks of gestation were randomly allocated to receive either labetalol or methyldopa (50 patients each) plus standard care (treatment group) or only standard care (50 patients) (control group)." | 5.16 | Role of antihypertensive therapy in mild to moderate pregnancy-induced hypertension: a prospective randomized study comparing labetalol with alpha methyldopa. ( Jabeen, F; Malik, AR; Mir, S; Molvi, SN; Rana, VS, 2012) |
| "To determine the need for, and efficacy of, treatment with labetalol in women with mild-to-moderate pregnancy induced hypertension (PIH)." | 5.07 | A randomised placebo controlled trial of labetalol in the treatment of mild to moderate pregnancy induced hypertension. ( Broughton Pipkin, F; Pickles, CJ; Symonds, EM, 1992) |
| "The effects of a nonselective beta-adrenergic blocking drug with beta-2 agonist activity (dilevalol 200 mg) on proteinuria and renal hemodynamics were evaluated in a double-blind crossover study versus an ACE inhibitor (enalapril 5 mg) in eight patients with glomerulonephritis, moderate renal function impairment and proteinuria greater than 1 g/24 hr." | 5.07 | Renal hemodynamics and reduction of proteinuria by a vasodilating beta blocker versus an ACE inhibitor. ( Erley, CM; Harrer, U; Krämer, BK; Risler, T, 1992) |
| "The aim of the study was to investigate cord blood leptin concentrations and their relationship to birth weight and gender in term pregnancies complicated by pre-eclampsia." | 3.70 | Serum leptin concentration in cord blood: relationship to birth weight and gender in pregnancies complicated by pre-eclampsia. ( Hartmann, BW; Laml, T; Preyer, O; Ruecklinger, E; Soeregi, G; Wagenbichler, P, 2000) |
| "This study reports the results that were obtained in 56 cases of arterial hypertension in pregnancy solely by beta-blocking with Atenolol or Labetalol." | 3.66 | [Effect of 2 beta-blockers on arterial hypertension during pregnancy. Results of a prospective study on 56 pregnant hypertensive women treated with atenolol and labetalol]. ( Beauséjour, B; Blazquez, G; Faurie, C; Flouvat, B; Gérard, J; Lardoux, H; Rousset, D, 1983) |
| "Labetalol was well tolerated and no significant maternal toxicity was noted." | 2.67 | Does labetalol influence the development of proteinuria in pregnancy hypertension? A randomised controlled study. ( Campbell, DM; Cruickshank, DJ; MacGillivray, I; Robertson, AA, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alexander, JM | 1 |
| Wilson, KL | 1 |
| Kujal, P | 1 |
| Chábová, VČ | 1 |
| Vernerová, Z | 1 |
| Walkowska, A | 1 |
| Kompanowska-Jezierska, E | 1 |
| Sadowski, J | 1 |
| Vaňourková, Z | 1 |
| Husková, Z | 1 |
| Opočenský, M | 1 |
| Skaroupková, P | 1 |
| Schejbalová, S | 1 |
| Kramer, HJ | 1 |
| Rakušan, D | 1 |
| Malý, J | 1 |
| Netuka, I | 1 |
| Vaněčková, I | 1 |
| Kopkan, L | 1 |
| Cervenka, L | 1 |
| Molvi, SN | 1 |
| Mir, S | 1 |
| Rana, VS | 1 |
| Jabeen, F | 1 |
| Malik, AR | 1 |
| Cachat, F | 1 |
| Bogaru, A | 1 |
| Micheli, JL | 1 |
| Lepori, D | 1 |
| Guignard, JP | 1 |
| Gérard, J | 1 |
| Blazquez, G | 1 |
| Lardoux, H | 1 |
| Beauséjour, B | 1 |
| Faurie, C | 1 |
| Rousset, D | 1 |
| Flouvat, B | 1 |
| Laml, T | 1 |
| Hartmann, BW | 1 |
| Preyer, O | 1 |
| Ruecklinger, E | 1 |
| Soeregi, G | 1 |
| Wagenbichler, P | 1 |
| Pickles, CJ | 1 |
| Broughton Pipkin, F | 1 |
| Symonds, EM | 1 |
| Erley, CM | 1 |
| Harrer, U | 1 |
| Krämer, BK | 1 |
| Risler, T | 1 |
| Cruickshank, DJ | 1 |
| Robertson, AA | 1 |
| Campbell, DM | 1 |
| MacGillivray, I | 1 |
1 review available for labetalol and Proteinuria
| Article | Year |
|---|---|
Hypertensive emergencies of pregnancy.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Creatine; Diuretics; Emergency Medicine; Female; | 2013 |
4 trials available for labetalol and Proteinuria
| Article | Year |
|---|---|
Role of antihypertensive therapy in mild to moderate pregnancy-induced hypertension: a prospective randomized study comparing labetalol with alpha methyldopa.
Topics: Adult; Antihypertensive Agents; Cesarean Section; Female; Humans; Hypertension, Pregnancy-Induced; I | 2012 |
A randomised placebo controlled trial of labetalol in the treatment of mild to moderate pregnancy induced hypertension.
Topics: Administration, Oral; Adult; Female; Gestational Age; Humans; Hypertension; Labetalol; Length of Sta | 1992 |
Renal hemodynamics and reduction of proteinuria by a vasodilating beta blocker versus an ACE inhibitor.
Topics: Adult; Blood Pressure; Double-Blind Method; Enalapril; Female; Glomerular Filtration Rate; Humans; L | 1992 |
Does labetalol influence the development of proteinuria in pregnancy hypertension? A randomised controlled study.
Topics: Adult; Female; Humans; Hypertension; Labetalol; Pregnancy; Pregnancy Complications; Pregnancy Compli | 1992 |
4 other studies available for labetalol and Proteinuria
| Article | Year |
|---|---|
Similar renoprotection after renin-angiotensin-dependent and -independent antihypertensive therapy in 5/6-nephrectomized Ren-2 transgenic rats: are there blood pressure-independent effects?
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme | 2010 |
Severe hypertension and massive proteinuria in a newborn with renal artery stenosis.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aorta, Abdominal; Blood Pressure; | 2004 |
[Effect of 2 beta-blockers on arterial hypertension during pregnancy. Results of a prospective study on 56 pregnant hypertensive women treated with atenolol and labetalol].
Topics: Adolescent; Adult; Atenolol; Delivery, Obstetric; Ethanolamines; Female; Fetal Heart; Fetal Monitori | 1983 |
Serum leptin concentration in cord blood: relationship to birth weight and gender in pregnancies complicated by pre-eclampsia.
Topics: Adult; Antihypertensive Agents; Birth Weight; Female; Fetal Blood; Gestational Age; Humans; Hyperten | 2000 |