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labetalol and Proteinuria

labetalol has been researched along with Proteinuria in 9 studies

Labetalol: A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.
labetalol : A diastereoisomeric mixture of approximately equal amounts of all four possible stereoisomers ((R,S)-labetolol, (S,R)-labetolol, (S,S)-labetalol and (R,R)-labetalol). It is an adrenergic antagonist used to treat high blood pressure.
2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide : A member of the class of benzamides that is benzamide substituted by a hydroxy group at position 2 and by a 1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl group at position 5.

Proteinuria: The presence of proteins in the urine, an indicator of KIDNEY DISEASES.

Research Excerpts

ExcerptRelevanceReference
"A total of 150 consecutive pregnant women without proteinuria and with physician-recorded systolic BP of 140-160 mmHg and/or diastolic BP of 90-105 mmHg on two occasions ≥6 h apart between 20 and 38 weeks of gestation were randomly allocated to receive either labetalol or methyldopa (50 patients each) plus standard care (treatment group) or only standard care (50 patients) (control group)."9.16Role of antihypertensive therapy in mild to moderate pregnancy-induced hypertension: a prospective randomized study comparing labetalol with alpha methyldopa. ( Jabeen, F; Malik, AR; Mir, S; Molvi, SN; Rana, VS, 2012)
"To determine the need for, and efficacy of, treatment with labetalol in women with mild-to-moderate pregnancy induced hypertension (PIH)."9.07A randomised placebo controlled trial of labetalol in the treatment of mild to moderate pregnancy induced hypertension. ( Broughton Pipkin, F; Pickles, CJ; Symonds, EM, 1992)
"The aim of the study was to investigate cord blood leptin concentrations and their relationship to birth weight and gender in term pregnancies complicated by pre-eclampsia."7.70Serum leptin concentration in cord blood: relationship to birth weight and gender in pregnancies complicated by pre-eclampsia. ( Hartmann, BW; Laml, T; Preyer, O; Ruecklinger, E; Soeregi, G; Wagenbichler, P, 2000)
"This study reports the results that were obtained in 56 cases of arterial hypertension in pregnancy solely by beta-blocking with Atenolol or Labetalol."7.66[Effect of 2 beta-blockers on arterial hypertension during pregnancy. Results of a prospective study on 56 pregnant hypertensive women treated with atenolol and labetalol]. ( Beauséjour, B; Blazquez, G; Faurie, C; Flouvat, B; Gérard, J; Lardoux, H; Rousset, D, 1983)
"Labetalol was well tolerated and no significant maternal toxicity was noted."6.67Does labetalol influence the development of proteinuria in pregnancy hypertension? A randomised controlled study. ( Campbell, DM; Cruickshank, DJ; MacGillivray, I; Robertson, AA, 1992)
"A total of 150 consecutive pregnant women without proteinuria and with physician-recorded systolic BP of 140-160 mmHg and/or diastolic BP of 90-105 mmHg on two occasions ≥6 h apart between 20 and 38 weeks of gestation were randomly allocated to receive either labetalol or methyldopa (50 patients each) plus standard care (treatment group) or only standard care (50 patients) (control group)."5.16Role of antihypertensive therapy in mild to moderate pregnancy-induced hypertension: a prospective randomized study comparing labetalol with alpha methyldopa. ( Jabeen, F; Malik, AR; Mir, S; Molvi, SN; Rana, VS, 2012)
"To determine the need for, and efficacy of, treatment with labetalol in women with mild-to-moderate pregnancy induced hypertension (PIH)."5.07A randomised placebo controlled trial of labetalol in the treatment of mild to moderate pregnancy induced hypertension. ( Broughton Pipkin, F; Pickles, CJ; Symonds, EM, 1992)
"The effects of a nonselective beta-adrenergic blocking drug with beta-2 agonist activity (dilevalol 200 mg) on proteinuria and renal hemodynamics were evaluated in a double-blind crossover study versus an ACE inhibitor (enalapril 5 mg) in eight patients with glomerulonephritis, moderate renal function impairment and proteinuria greater than 1 g/24 hr."5.07Renal hemodynamics and reduction of proteinuria by a vasodilating beta blocker versus an ACE inhibitor. ( Erley, CM; Harrer, U; Krämer, BK; Risler, T, 1992)
"The aim of the study was to investigate cord blood leptin concentrations and their relationship to birth weight and gender in term pregnancies complicated by pre-eclampsia."3.70Serum leptin concentration in cord blood: relationship to birth weight and gender in pregnancies complicated by pre-eclampsia. ( Hartmann, BW; Laml, T; Preyer, O; Ruecklinger, E; Soeregi, G; Wagenbichler, P, 2000)
"This study reports the results that were obtained in 56 cases of arterial hypertension in pregnancy solely by beta-blocking with Atenolol or Labetalol."3.66[Effect of 2 beta-blockers on arterial hypertension during pregnancy. Results of a prospective study on 56 pregnant hypertensive women treated with atenolol and labetalol]. ( Beauséjour, B; Blazquez, G; Faurie, C; Flouvat, B; Gérard, J; Lardoux, H; Rousset, D, 1983)
"Labetalol was well tolerated and no significant maternal toxicity was noted."2.67Does labetalol influence the development of proteinuria in pregnancy hypertension? A randomised controlled study. ( Campbell, DM; Cruickshank, DJ; MacGillivray, I; Robertson, AA, 1992)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's3 (33.33)18.2507
2000's2 (22.22)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alexander, JM1
Wilson, KL1
Kujal, P1
Chábová, VČ1
Vernerová, Z1
Walkowska, A1
Kompanowska-Jezierska, E1
Sadowski, J1
Vaňourková, Z1
Husková, Z1
Opočenský, M1
Skaroupková, P1
Schejbalová, S1
Kramer, HJ1
Rakušan, D1
Malý, J1
Netuka, I1
Vaněčková, I1
Kopkan, L1
Cervenka, L1
Molvi, SN1
Mir, S1
Rana, VS1
Jabeen, F1
Malik, AR1
Cachat, F1
Bogaru, A1
Micheli, JL1
Lepori, D1
Guignard, JP1
Gérard, J1
Blazquez, G1
Lardoux, H1
Beauséjour, B1
Faurie, C1
Rousset, D1
Flouvat, B1
Laml, T1
Hartmann, BW1
Preyer, O1
Ruecklinger, E1
Soeregi, G1
Wagenbichler, P1
Pickles, CJ1
Broughton Pipkin, F1
Symonds, EM1
Erley, CM1
Harrer, U1
Krämer, BK1
Risler, T1
Cruickshank, DJ1
Robertson, AA1
Campbell, DM1
MacGillivray, I1

Reviews

1 review available for labetalol and Proteinuria

ArticleYear
Hypertensive emergencies of pregnancy.
    Obstetrics and gynecology clinics of North America, 2013, Volume: 40, Issue:1

    Topics: Antihypertensive Agents; Calcium Channel Blockers; Creatine; Diuretics; Emergency Medicine; Female;

2013

Trials

4 trials available for labetalol and Proteinuria

ArticleYear
Role of antihypertensive therapy in mild to moderate pregnancy-induced hypertension: a prospective randomized study comparing labetalol with alpha methyldopa.
    Archives of gynecology and obstetrics, 2012, Volume: 285, Issue:6

    Topics: Adult; Antihypertensive Agents; Cesarean Section; Female; Humans; Hypertension, Pregnancy-Induced; I

2012
A randomised placebo controlled trial of labetalol in the treatment of mild to moderate pregnancy induced hypertension.
    British journal of obstetrics and gynaecology, 1992, Volume: 99, Issue:12

    Topics: Administration, Oral; Adult; Female; Gestational Age; Humans; Hypertension; Labetalol; Length of Sta

1992
Renal hemodynamics and reduction of proteinuria by a vasodilating beta blocker versus an ACE inhibitor.
    Kidney international, 1992, Volume: 41, Issue:5

    Topics: Adult; Blood Pressure; Double-Blind Method; Enalapril; Female; Glomerular Filtration Rate; Humans; L

1992
Does labetalol influence the development of proteinuria in pregnancy hypertension? A randomised controlled study.
    European journal of obstetrics, gynecology, and reproductive biology, 1992, Jun-16, Volume: 45, Issue:1

    Topics: Adult; Female; Humans; Hypertension; Labetalol; Pregnancy; Pregnancy Complications; Pregnancy Compli

1992

Other Studies

4 other studies available for labetalol and Proteinuria

ArticleYear
Similar renoprotection after renin-angiotensin-dependent and -independent antihypertensive therapy in 5/6-nephrectomized Ren-2 transgenic rats: are there blood pressure-independent effects?
    Clinical and experimental pharmacology & physiology, 2010, Volume: 37, Issue:12

    Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme

2010
Severe hypertension and massive proteinuria in a newborn with renal artery stenosis.
    Pediatric nephrology (Berlin, Germany), 2004, Volume: 19, Issue:5

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aorta, Abdominal; Blood Pressure;

2004
[Effect of 2 beta-blockers on arterial hypertension during pregnancy. Results of a prospective study on 56 pregnant hypertensive women treated with atenolol and labetalol].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 1983, Volume: 12, Issue:8

    Topics: Adolescent; Adult; Atenolol; Delivery, Obstetric; Ethanolamines; Female; Fetal Heart; Fetal Monitori

1983
Serum leptin concentration in cord blood: relationship to birth weight and gender in pregnancies complicated by pre-eclampsia.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2000, Volume: 14, Issue:6

    Topics: Adult; Antihypertensive Agents; Birth Weight; Female; Fetal Blood; Gestational Age; Humans; Hyperten

2000