labetalol has been researched along with Obstructive Lung Diseases in 10 studies
Labetalol: A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.
labetalol : A diastereoisomeric mixture of approximately equal amounts of all four possible stereoisomers ((R,S)-labetolol, (S,R)-labetolol, (S,S)-labetalol and (R,R)-labetalol). It is an adrenergic antagonist used to treat high blood pressure.
2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide : A member of the class of benzamides that is benzamide substituted by a hydroxy group at position 2 and by a 1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "1 The effects of atenolol (100 mg), a cardioselective beta-adrenoceptor blocking agent, and labetalol (300 mg), a combined alpha- and non-selective beta-adrenoceptor blocking agent given in single doses were examined in a double-blind placebo controlled study in 11 asthmatic patients with hypertension." | 9.05 | Comparison of the effects of single doses of atenolol and labetalol on airways obstruction in patients with hypertension and asthma. ( Beevers, DG; Jackson, SH, 1983) |
| "Verapamil was devoid of any such effect." | 6.66 | Evaluation of verapamil in the treatment of hypertension. ( Anavekar, SN; Doyle, AE, 1986) |
| " The effects of labetalol and hydrochlorothiazide on the hypertension and ventilatory function of patients with both hypertension and mild reversible chronic pulmonary disease were compared." | 5.05 | Comparison of the effects of labetalol and hydrochlorothiazide on the ventilatory function of hypertensive patients with mild chronic obstructive pulmonary disease. ( Chetty, KG; Light, RW; Stansbury, DW, 1983) |
| "1 The effects of atenolol (100 mg), a cardioselective beta-adrenoceptor blocking agent, and labetalol (300 mg), a combined alpha- and non-selective beta-adrenoceptor blocking agent given in single doses were examined in a double-blind placebo controlled study in 11 asthmatic patients with hypertension." | 5.05 | Comparison of the effects of single doses of atenolol and labetalol on airways obstruction in patients with hypertension and asthma. ( Beevers, DG; Jackson, SH, 1983) |
| "Labetalol, a new beta-adrenoceptor blocking drug with ancillary alpha-adrenoceptor blocking and vasodilating activity, will soon be available in the United States for the treatment of hypertension." | 3.66 | Labetalol: an alpha- and beta-adrenoceptor blocking drug. ( Frishman, WH; Michelson, EL, 1983) |
| "Treatment with labetalol, on the other hand, led to an improvement in respiratory function." | 2.66 | Respiratory effects of four adrenergic blocking agents combined with a diuretic in treating hypertension with concurrent chronic obstructive lung disease. ( Dal Negro, RW; Pomari, C; Trevisan, F; Turco, P; Zoccatelli, O, 1986) |
| "Verapamil was devoid of any such effect." | 2.66 | Evaluation of verapamil in the treatment of hypertension. ( Anavekar, SN; Doyle, AE, 1986) |
| "Propranolol was the only drug that significantly increased airways obstruction (FEV1, specific airways resistance)." | 2.65 | Labetalol, beta blockers, and acute deterioration of chronic airway obstruction. ( Adam, WR; Barter, CE; Meagher, EJ, 1982) |
| "Verapamil was devoid of any such effect." | 2.65 | A double-blind comparison of verapamil and labetalol in hypertensive patients with coexisting chronic obstructive airways disease. ( Adam, WR; Anavekar, SN; Barter, C; Doyle, AE, 1982) |
| "Labetalol is a new adrenergic antagonist with both alpha- and beta-blocking effects." | 2.65 | Effects of labetalol in hypertensive patients with chronic obstructive pulmonary disease. ( Burford, JG; Conrad, SA; George, RB; Kinasewitz, GT; Manocha, K, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adam, WR | 2 |
| Meagher, EJ | 1 |
| Barter, CE | 1 |
| Michelson, EL | 1 |
| Frishman, WH | 1 |
| Anavekar, SN | 2 |
| Barter, C | 1 |
| Doyle, AE | 2 |
| George, RB | 1 |
| Manocha, K | 1 |
| Burford, JG | 1 |
| Conrad, SA | 1 |
| Kinasewitz, GT | 1 |
| Light, RW | 1 |
| Chetty, KG | 1 |
| Stansbury, DW | 1 |
| Jackson, SH | 1 |
| Beevers, DG | 1 |
| Turco, P | 2 |
| Dal Negro, R | 1 |
| Opie, LH | 1 |
| Dal Negro, RW | 1 |
| Zoccatelli, O | 1 |
| Pomari, C | 1 |
| Trevisan, F | 1 |
7 trials available for labetalol and Obstructive Lung Diseases
| Article | Year |
|---|---|
Labetalol, beta blockers, and acute deterioration of chronic airway obstruction.
Topics: Adrenergic beta-Antagonists; Aged; Atenolol; Ethanolamines; Humans; Hypertension; Labetalol; Lung Di | 1982 |
A double-blind comparison of verapamil and labetalol in hypertensive patients with coexisting chronic obstructive airways disease.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Ethan | 1982 |
Effects of labetalol in hypertensive patients with chronic obstructive pulmonary disease.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Ethanolamines; Exercise | 1983 |
Comparison of the effects of labetalol and hydrochlorothiazide on the ventilatory function of hypertensive patients with mild chronic obstructive pulmonary disease.
Topics: Aged; Clinical Trials as Topic; Double-Blind Method; Ethanolamines; Forced Expiratory Volume; Humans | 1983 |
Comparison of the effects of single doses of atenolol and labetalol on airways obstruction in patients with hypertension and asthma.
Topics: Adult; Asthma; Atenolol; Blood Pressure; Ethanolamines; Female; Forced Expiratory Volume; Humans; Hy | 1983 |
Respiratory effects of four adrenergic blocking agents combined with a diuretic in treating hypertension with concurrent chronic obstructive lung disease.
Topics: Adrenergic beta-Antagonists; Airway Resistance; Atenolol; Chlorthalidone; Drug Therapy, Combination; | 1986 |
Evaluation of verapamil in the treatment of hypertension.
Topics: Adult; Benzothiadiazines; Clinical Trials as Topic; Diuretics; Drug Therapy, Combination; Female; He | 1986 |
3 other studies available for labetalol and Obstructive Lung Diseases
| Article | Year |
|---|---|
Labetalol: an alpha- and beta-adrenoceptor blocking drug.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Ethanolamines; Humans; Hypertension; Labe | 1983 |
[Acute and chronic respiratory effects of an alpha-beta antagonist with antihypertensive action].
Topics: Aged; Bronchial Spasm; Bronchitis; Ethanolamines; Humans; Hypertension; Labetalol; Lung Diseases, Ob | 1980 |
Mechanism of smooth muscle contraction: relevance to safety of beta-adrenergic blockade in hypertensive patients with reversible chronic obstructive airways disease.
Topics: Adrenergic beta-Antagonists; Atenolol; Bronchi; Calcium Channel Blockers; Calmodulin; Celiprolol; Cy | 1986 |