labetalol has been researched along with Intraocular Pressure in 7 studies
Labetalol: A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.
labetalol : A diastereoisomeric mixture of approximately equal amounts of all four possible stereoisomers ((R,S)-labetolol, (S,R)-labetolol, (S,S)-labetalol and (R,R)-labetalol). It is an adrenergic antagonist used to treat high blood pressure.
2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide : A member of the class of benzamides that is benzamide substituted by a hydroxy group at position 2 and by a 1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl group at position 5.
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The beta-blocking agent Nadolol and the beta- and alpha-blocking agent Labetalol were screened for their potential efficacy on intraocular pressure (IOP) in glaucoma." | 9.05 | Nadolol and labetalol: comparative efficacy of two beta-blocking agents in glaucoma. ( Kontić, D; Krieglstein, GK, 1981) |
| "Labetalol was found to be about 3." | 5.26 | Hypotensive effect of labetalol on intraocular pressure in rabbits: in relation to its alpha- and beta-adrenergic blocking action on the cardiovascular system. ( Abiko, Y; Hosaka, A; Kogure, H, 1981) |
| "The beta-blocking agent Nadolol and the beta- and alpha-blocking agent Labetalol were screened for their potential efficacy on intraocular pressure (IOP) in glaucoma." | 5.05 | Nadolol and labetalol: comparative efficacy of two beta-blocking agents in glaucoma. ( Kontić, D; Krieglstein, GK, 1981) |
| "Labetalol was found to be about 3." | 1.26 | Hypotensive effect of labetalol on intraocular pressure in rabbits: in relation to its alpha- and beta-adrenergic blocking action on the cardiovascular system. ( Abiko, Y; Hosaka, A; Kogure, H, 1981) |
| "Labetalol has a unique and profound effect on the IOP of rabbits, in contrast to pure beta-adrenergic blockers which have little or no effect in this animal." | 1.26 | Ocular hypotensive action of labetalol. ( Leopold, IH; Murray, DL, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Krieglstein, GK | 1 |
| Kontić, D | 1 |
| Kogure, H | 2 |
| Hosaka, A | 1 |
| Abiko, Y | 2 |
| Bonomi, L | 1 |
| Perfetti, S | 1 |
| Bellucci, R | 1 |
| Massa, F | 1 |
| Noya, E | 1 |
| Murakami, K | 1 |
| Murray, DL | 2 |
| Podos, SM | 1 |
| Wei, C | 1 |
| Leopold, IH | 2 |
| Palkama, A | 1 |
| Uusitalo, H | 1 |
| Raij, K | 1 |
| Uusitalo, R | 1 |
1 trial available for labetalol and Intraocular Pressure
| Article | Year |
|---|---|
Nadolol and labetalol: comparative efficacy of two beta-blocking agents in glaucoma.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Ethanolamines; Glaucoma; Heart Rate; Humans; Intraocula | 1981 |
6 other studies available for labetalol and Intraocular Pressure
| Article | Year |
|---|---|
Hypotensive effect of labetalol on intraocular pressure in rabbits: in relation to its alpha- and beta-adrenergic blocking action on the cardiovascular system.
Topics: Animals; Blood Pressure; Ethanolamines; Heart Rate; Intraocular Pressure; Labetalol; Male; Phentolam | 1981 |
Ocular hypotensive action of labetalol in rabbit and human eyes.
Topics: Animals; Dose-Response Relationship, Drug; Ethanolamines; Female; Glaucoma, Open-Angle; Humans; Intr | 1981 |
[Ocular and hemodynamic effect of labetalol in rabbits (author's transl)].
Topics: Animals; Blood Pressure; Ethanolamines; Heart Rate; Intraocular Pressure; Labetalol; Male; Rabbits | 1980 |
Ocular effects in normal rabbits of topically applied labetalol: a combined alpha- and beta-adrenergic antagonist.
Topics: Animals; Aqueous Humor; Dose-Response Relationship, Drug; Ethanolamines; Eye; Female; Intraocular Pr | 1979 |
Ocular hypotensive action of labetalol.
Topics: Animals; Ethanolamines; Female; Intraocular Pressure; Isoproterenol; Labetalol; Norepinephrine; p-Hy | 1979 |
Comparison of the effects of adrenergic agonists and alpha-, beta 1-, beta 2-antagonists on the intraocular pressure and adenylate cyclase activity in the ciliary processes of the rabbit.
Topics: Acebutolol; Adenylyl Cyclases; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic b | 1985 |