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labetalol and Intracranial Aneurysm

labetalol has been researched along with Intracranial Aneurysm in 10 studies

Labetalol: A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.
labetalol : A diastereoisomeric mixture of approximately equal amounts of all four possible stereoisomers ((R,S)-labetolol, (S,R)-labetolol, (S,S)-labetalol and (R,R)-labetalol). It is an adrenergic antagonist used to treat high blood pressure.
2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide : A member of the class of benzamides that is benzamide substituted by a hydroxy group at position 2 and by a 1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl group at position 5.

Intracranial Aneurysm: Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (

Research Excerpts

ExcerptRelevanceReference
"The episode of profound hypotension which occurred after initiating a labetolol infusion required maximal combined vasopressor therapy to restore the blood pressure suggesting that this patient demonstrated an extreme sensitivity to labetalol."7.73Case report: profound hypotension associated with labetalol therapy in a patient with cerebral aneurysms and subarachnoid hemorrhage. ( Baker, AJ; Choi, M; Hare, GM; Jivraj, S; Mazer, CD, 2006)
"The episode of profound hypotension which occurred after initiating a labetolol infusion required maximal combined vasopressor therapy to restore the blood pressure suggesting that this patient demonstrated an extreme sensitivity to labetalol."3.73Case report: profound hypotension associated with labetalol therapy in a patient with cerebral aneurysms and subarachnoid hemorrhage. ( Baker, AJ; Choi, M; Hare, GM; Jivraj, S; Mazer, CD, 2006)
"In the case of hypertensive encephalopathy, the lowering of blood pressure is therapeutic as well as diagnostic."2.43[Antihypertensive management in acute cerebral stroke]. ( Ziliene, V, 2005)
" The lack of an adverse outcome in this patient does not prove the safety of this technique in patients with liver disease; further studies of this patient group are required."1.27Safe use of induced hypotension in a patient with cirrhotic liver disease. ( Roth, S; Run, S, 1987)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19906 (60.00)18.7374
1990's1 (10.00)18.2507
2000's3 (30.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ziliene, V1
Jivraj, S1
Mazer, CD1
Baker, AJ1
Choi, M1
Hare, GM1
Mocco, J1
Rose, JC1
Komotar, RJ1
Mayer, SA1
Lüben, V2
Hempelmann, G2
Rieder, W1
Zierski, J1
Lam, AM1
Maubec, E1
Matheron, R1
Tannières, ML1
Benhaim, JP1
Arbouet, C1
Orlowski, JP1
Shiesley, D1
Vidt, DG1
Barnett, GH1
Little, JR1
Charlot, M1
Chacornac, R1
Zannini, C1
Roth, S1
Run, S1

Reviews

3 reviews available for labetalol and Intracranial Aneurysm

ArticleYear
[Antihypertensive management in acute cerebral stroke].
    Medicina (Kaunas, Lithuania), 2005, Volume: 41, Issue:1

    Topics: Acute Disease; Adult; Antihypertensive Agents; Brain Injuries; Cerebrovascular Circulation; Emergenc

2005
Blood pressure management in patients with intracerebral and subarachnoid hemorrhage.
    Neurosurgery clinics of North America, 2006, Volume: 17 Suppl 1

    Topics: Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Blood Volume; Brain; Brain Ischemia; E

2006
The choice of controlled hypotension during repair of intracranial aneurysms: techniques and complications.
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1990, Volume: 31, Issue:6

    Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Constriction; Humans; Hypotension, Controlled

1990

Other Studies

7 other studies available for labetalol and Intracranial Aneurysm

ArticleYear
Case report: profound hypotension associated with labetalol therapy in a patient with cerebral aneurysms and subarachnoid hemorrhage.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2006, Volume: 53, Issue:7

    Topics: Antihypertensive Agents; Bradycardia; Cardiotonic Agents; Dopamine; Epinephrine; Female; Humans; Hyp

2006
Improved deep controlled hypotension in aneurysmal surgery.
    Acta neurochirurgica, 1982, Volume: 60, Issue:3-4

    Topics: Adrenergic beta-Antagonists; Drug Interactions; Ethanolamines; Ferricyanides; Hemodynamics; Humans;

1982
[Labetalol for the management of hypertensive crises during surgery of cerebral aneurysm; a haemodynamic study (author's transl)].
    Anasthesie, Intensivtherapie, Notfallmedizin, 1981, Volume: 16, Issue:4

    Topics: Adolescent; Adult; Blood Pressure; Ethanolamines; Heart Rate; Hemodynamics; Humans; Hypertension; Hy

1981
[Effect of labetalol on the hemodynamic response to sodium nitroprusside].
    Cahiers d'anesthesiologie, 1988, Volume: 36, Issue:3

    Topics: Adult; Blood Pressure; Cardiac Output; Female; Ferricyanides; Heart Rate; Hemodynamics; Humans; Hypo

1988
Labetalol to control blood pressure after cerebrovascular surgery.
    Critical care medicine, 1988, Volume: 16, Issue:8

    Topics: Adolescent; Adult; Aged; Arteriovenous Malformations; Brain; Female; Humans; Hypertension; Infusions

1988
[Labetalol and controlled arterial hypotension in the surgery of intracranial aneurysms].
    Minerva anestesiologica, 1987, Volume: 53, Issue:5

    Topics: Adult; Humans; Hypotension, Controlled; Intracranial Aneurysm; Labetalol; Middle Aged; Pulmonary Gas

1987
Safe use of induced hypotension in a patient with cirrhotic liver disease.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1987, Volume: 34, Issue:2

    Topics: Adult; Anesthesia, General; Female; Humans; Hypotension, Controlled; Intracranial Aneurysm; Labetalo

1987