labetalol has been researched along with Intermittent Claudication in 5 studies
Labetalol: A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.
labetalol : A diastereoisomeric mixture of approximately equal amounts of all four possible stereoisomers ((R,S)-labetolol, (S,R)-labetolol, (S,S)-labetalol and (R,R)-labetalol). It is an adrenergic antagonist used to treat high blood pressure.
2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide : A member of the class of benzamides that is benzamide substituted by a hydroxy group at position 2 and by a 1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl group at position 5.
Intermittent Claudication: A symptom complex characterized by pain and weakness in SKELETAL MUSCLE group associated with exercise, such as leg pain and weakness brought on by walking. Such muscle limpness disappears after a brief rest and is often relates to arterial STENOSIS; muscle ISCHEMIA; and accumulation of LACTATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a six month placebo-controlled cross-over trial twenty patients with hypertension and peripheral arterial disease were randomised to captopril 25 mg twice daily, atenolol 100 mg once daily, labetalol 200 mg twice daily, or pindolol 10 mg twice daily for one month." | 9.06 | Placebo-controlled comparison of captopril, atenolol, labetalol, and pindolol in hypertension complicated by intermittent claudication. ( Breckenridge, A; McLoughlin, GA; Roberts, DH; Tsao, Y, 1987) |
| " Heart rate was lowest during propranolol dosing and blood pressure was lowest during labetalol dosing irrespective of the labetalol dose used." | 6.66 | Chronic effects of labetalol, pindolol, and propranolol on calf blood flow in intermittent claudication. ( Lepäntalo, M, 1985) |
| "In a six month placebo-controlled cross-over trial twenty patients with hypertension and peripheral arterial disease were randomised to captopril 25 mg twice daily, atenolol 100 mg once daily, labetalol 200 mg twice daily, or pindolol 10 mg twice daily for one month." | 5.06 | Placebo-controlled comparison of captopril, atenolol, labetalol, and pindolol in hypertension complicated by intermittent claudication. ( Breckenridge, A; McLoughlin, GA; Roberts, DH; Tsao, Y, 1987) |
| "Recognition of algodystrophy is important to avoid further vascular surgery which will exacerbate the symptoms." | 1.27 | Algodystrophy after aortic bifurcation surgery. ( Churcher, MD, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Churcher, MD | 1 |
| Lepäntalo, M | 3 |
| Roberts, DH | 1 |
| Tsao, Y | 1 |
| McLoughlin, GA | 1 |
| Breckenridge, A | 1 |
| Lindström, BL | 1 |
| Tötterman, KJ | 1 |
3 trials available for labetalol and Intermittent Claudication
| Article | Year |
|---|---|
Beta blockade and intermittent claudication.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Clinical Trials as Topic; Coronary Disease; Female; Gait; | 1985 |
Placebo-controlled comparison of captopril, atenolol, labetalol, and pindolol in hypertension complicated by intermittent claudication.
Topics: Atenolol; Blood Pressure; Captopril; Clinical Trials as Topic; Double-Blind Method; Exercise Test; F | 1987 |
Chronic effects of labetalol, pindolol, and propranolol on calf blood flow in intermittent claudication.
Topics: Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Ethanolamines; Heart Rate; Huma | 1985 |
2 other studies available for labetalol and Intermittent Claudication
| Article | Year |
|---|---|
Algodystrophy after aortic bifurcation surgery.
Topics: Aged; Aorta; Aortography; Autonomic Nerve Block; Female; Humans; Intermittent Claudication; Labetalo | 1984 |
Adrenoceptor blocking drugs and cold feet in intermittent claudication.
Topics: Aged; Foot; Humans; Hypertension; Intermittent Claudication; Labetalol; Male; Middle Aged; Propranol | 1986 |