Page last updated: 2024-10-30

labetalol and Infant, Newborn, Diseases

labetalol has been researched along with Infant, Newborn, Diseases in 8 studies

Labetalol: A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.
labetalol : A diastereoisomeric mixture of approximately equal amounts of all four possible stereoisomers ((R,S)-labetolol, (S,R)-labetolol, (S,S)-labetalol and (R,R)-labetalol). It is an adrenergic antagonist used to treat high blood pressure.
2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide : A member of the class of benzamides that is benzamide substituted by a hydroxy group at position 2 and by a 1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl group at position 5.

Infant, Newborn, Diseases: Diseases of newborn infants present at birth (congenital) or developing within the first month of birth. It does not include hereditary diseases not manifesting at birth or within the first 30 days of life nor does it include inborn errors of metabolism. Both HEREDITARY DISEASES and METABOLISM, INBORN ERRORS are available as general concepts.

Research Excerpts

ExcerptRelevanceReference
"This study aimed to evaluate the maternal and fetal results in women undergoing antihypertensive therapy (low aspirin or labetalol) with mild to severe chronic hypertension relative to women without medicines."9.34Treatment of pregnancy-induced hypertension compared with labetalol, low dose aspirin and placebo. ( Wang, F; Xiang, X; Zhao, N; Zhou, Z, 2020)
"Labetalol and methyldopa are the two antihypertensive drugs most frequently used to control blood pressure for hypertensive disorders of pregnancy."7.80Association between labetalol use for hypertension in pregnancy and adverse infant outcomes. ( Guo, Y; Krewski, D; Mattison, D; Nerenberg, K; Walker, MC; Wen, SW; Xie, RH, 2014)
"Labetalol is used to treat hypertensive crisis in women with preeclampsia."7.69Use of glucagon to treat neonatal low-output congestive heart failure after maternal labetalol therapy. ( Guillet, R; Stevens, TP, 1995)
"Hypotension is more common after maternal labetalol exposure, regardless of the dosage and route of administration."5.38Neonatal side effects of maternal labetalol treatment in severe preeclampsia. ( Heida, KY; Hulzebos, CV; Van Veen, TR; Zeeman, GG, 2012)
"This study aimed to evaluate the maternal and fetal results in women undergoing antihypertensive therapy (low aspirin or labetalol) with mild to severe chronic hypertension relative to women without medicines."5.34Treatment of pregnancy-induced hypertension compared with labetalol, low dose aspirin and placebo. ( Wang, F; Xiang, X; Zhao, N; Zhou, Z, 2020)
"Our findings suggest that neonates born to mothers exposed to β blockers in late pregnancy, including labetalol, are at elevated risk for neonatal hypoglycemia and bradycardia."3.83Late Pregnancy β Blocker Exposure and Risks of Neonatal Hypoglycemia and Bradycardia. ( Bateman, BT; Desai, RJ; Fischer, MA; Hernandez-Diaz, S; Huybrechts, KF; Maeda, A; Mogun, H; Patorno, E; Seely, EW, 2016)
"Labetalol and methyldopa are the two antihypertensive drugs most frequently used to control blood pressure for hypertensive disorders of pregnancy."3.80Association between labetalol use for hypertension in pregnancy and adverse infant outcomes. ( Guo, Y; Krewski, D; Mattison, D; Nerenberg, K; Walker, MC; Wen, SW; Xie, RH, 2014)
"Labetalol is used to treat hypertensive crisis in women with preeclampsia."3.69Use of glucagon to treat neonatal low-output congestive heart failure after maternal labetalol therapy. ( Guillet, R; Stevens, TP, 1995)
"Neonatal hypertension is increasingly recognized as dramatic improvements in neonatal intensive care, advancements in our understanding of neonatal physiology, and implementation of new therapies have led to improved survival of premature infants."2.61Neonatal hypertension: cases, causes, and clinical approach. ( Flynn, JT; Starr, MC, 2019)
"Hypotension is more common after maternal labetalol exposure, regardless of the dosage and route of administration."1.38Neonatal side effects of maternal labetalol treatment in severe preeclampsia. ( Heida, KY; Hulzebos, CV; Van Veen, TR; Zeeman, GG, 2012)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's1 (12.50)18.2507
2000's0 (0.00)29.6817
2010's4 (50.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Dublin, S1
Idu, A1
Avalos, LA1
Cheetham, TC1
Easterling, TR1
Chen, L1
Holt, VL1
Nance, N1
Bider-Canfield, Z1
Neugebauer, RS1
Reynolds, K1
Badon, SE1
Shortreed, SM1
Xiang, X1
Wang, F1
Zhao, N1
Zhou, Z1
Starr, MC1
Flynn, JT1
Xie, RH1
Guo, Y1
Krewski, D1
Mattison, D1
Walker, MC1
Nerenberg, K1
Wen, SW1
Bateman, BT1
Patorno, E1
Desai, RJ1
Seely, EW1
Mogun, H1
Maeda, A1
Fischer, MA1
Hernandez-Diaz, S1
Huybrechts, KF1
Heida, KY1
Zeeman, GG1
Van Veen, TR1
Hulzebos, CV1
Woods, DL1
Malan, AF1
Stevens, TP1
Guillet, R1

Reviews

1 review available for labetalol and Infant, Newborn, Diseases

ArticleYear
Neonatal hypertension: cases, causes, and clinical approach.
    Pediatric nephrology (Berlin, Germany), 2019, Volume: 34, Issue:5

    Topics: Administration, Intravenous; Antihypertensive Agents; Birth Weight; Blood Pressure; Blood Pressure D

2019

Trials

1 trial available for labetalol and Infant, Newborn, Diseases

ArticleYear
Treatment of pregnancy-induced hypertension compared with labetalol, low dose aspirin and placebo.
    Cellular and molecular biology (Noisy-le-Grand, France), 2020, Dec-31, Volume: 66, Issue:8

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Blood Pressure; Do

2020

Other Studies

6 other studies available for labetalol and Infant, Newborn, Diseases

ArticleYear
Maternal and neonatal outcomes of antihypertensive treatment in pregnancy: A retrospective cohort study.
    PloS one, 2022, Volume: 17, Issue:5

    Topics: Antihypertensive Agents; Birth Weight; Female; Humans; Hypertension, Pregnancy-Induced; Infant; Infa

2022
Association between labetalol use for hypertension in pregnancy and adverse infant outcomes.
    European journal of obstetrics, gynecology, and reproductive biology, 2014, Volume: 175

    Topics: Adult; Antihypertensive Agents; Female; Humans; Hypertension, Pregnancy-Induced; Infant, Newborn; In

2014
Late Pregnancy β Blocker Exposure and Risks of Neonatal Hypoglycemia and Bradycardia.
    Pediatrics, 2016, Volume: 138, Issue:3

    Topics: Adrenergic beta-Antagonists; Atenolol; Bradycardia; Cohort Studies; Female; Humans; Hypertension; Hy

2016
Neonatal side effects of maternal labetalol treatment in severe preeclampsia.
    Early human development, 2012, Volume: 88, Issue:7

    Topics: Adult; Antihypertensive Agents; Case-Control Studies; Female; Fetal Death; Humans; Infant Mortality;

2012
Side effects of labetalol in newborn infants.
    British journal of obstetrics and gynaecology, 1983, Volume: 90, Issue:9

    Topics: Ethanolamines; Female; Humans; Hypertension; Infant, Newborn; Infant, Newborn, Diseases; Labetalol;

1983
Use of glucagon to treat neonatal low-output congestive heart failure after maternal labetalol therapy.
    The Journal of pediatrics, 1995, Volume: 127, Issue:1

    Topics: Adult; Eclampsia; Female; Glucagon; Heart Failure; Humans; Infant, Newborn; Infant, Newborn, Disease

1995