Page last updated: 2024-10-30

labetalol and Hypotension, Postural

labetalol has been researched along with Hypotension, Postural in 8 studies

Labetalol: A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.
labetalol : A diastereoisomeric mixture of approximately equal amounts of all four possible stereoisomers ((R,S)-labetolol, (S,R)-labetolol, (S,S)-labetalol and (R,R)-labetalol). It is an adrenergic antagonist used to treat high blood pressure.
2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide : A member of the class of benzamides that is benzamide substituted by a hydroxy group at position 2 and by a 1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl group at position 5.

Research Excerpts

ExcerptRelevanceReference
"In 12 patients with resistant hypertension labetalol was added to existing therapy."7.66Labetalol in resistant hypertension. ( Hedstrand, H, 1982)
"In 12 patients with resistant hypertension labetalol was added to existing therapy."3.66Labetalol in resistant hypertension. ( Hedstrand, H, 1982)
" Dosage ranged from 100 to 2400 mg per day (mean 654 mg per day) and treatment was continued for between 6 and 18 months (mean 7."1.27Side-effects with long-term labetalol: an open study of 251 patients in a single centre. ( Tcherdakoff, P, 1983)
"Postural hypotension is a common side effect observed in the treatment of hypertension with various drugs."1.27Evaluation of the risk for drug-induced postural hypotension in an experimental model: investigations with carvedilol, prazosin, labetalol, and guanethidine. ( Bartsch, W; Böhm, E; Hooper, RG; Sponer, G; Strein, K, 1987)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19908 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tcherdakoff, P1
Hedstrand, H1
Dollery, CT1
Louis, WJ1
Brignell, MJ1
McNeil, JJ1
Christophidis, N1
Vajda, FJ1
Frick, MH1
Pörsti, P1
Bartsch, W1
Sponer, G1
Strein, K1
Böhm, E1
Hooper, RG1

Trials

1 trial available for labetalol and Hypotension, Postural

ArticleYear
Combined alpha- and beta-adrenoceptor blockade with labetalol in hypertension.
    British medical journal, 1976, May-01, Volume: 1, Issue:6017

    Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Depression, Chemical; Ethanolamines; Female;

1976

Other Studies

7 other studies available for labetalol and Hypotension, Postural

ArticleYear
Side-effects with long-term labetalol: an open study of 251 patients in a single centre.
    Pharmatherapeutica, 1983, Volume: 3, Issue:5

    Topics: Adult; Aged; Asthma; Ethanolamines; Female; Humans; Hypertension; Hypotension, Orthostatic; Labetalo

1983
Labetalol in resistant hypertension.
    Acta medica Scandinavica. Supplementum, 1982, Volume: 665

    Topics: Adult; Antihypertensive Agents; Drug Resistance; Drug Therapy, Combination; Ethanolamines; Female; H

1982
Closing remarks: current status of labetalol.
    British journal of clinical pharmacology, 1976, Volume: 3, Issue:4 Suppl 3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Ethanol

1976
Labetalol in hypertension.
    Lancet (London, England), 1977, May-28, Volume: 1, Issue:8022

    Topics: Adolescent; Adrenergic alpha-Antagonists; Antihypertensive Agents; Drug Evaluation; Ethanolamines; F

1977
Labetalol in hypertension.
    Lancet (London, England), 1978, Feb-25, Volume: 1, Issue:8061

    Topics: Dose-Response Relationship, Drug; Ethanolamines; Female; Humans; Hypertension; Hypotension, Orthosta

1978
Labetalol for hypertension.
    Drug and therapeutics bulletin, 1978, Nov-10, Volume: 16, Issue:23

    Topics: Ethanolamines; Humans; Hypertension; Hypotension, Orthostatic; Labetalol

1978
Evaluation of the risk for drug-induced postural hypotension in an experimental model: investigations with carvedilol, prazosin, labetalol, and guanethidine.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 11

    Topics: Animals; Blood Pressure; Carbazoles; Carvedilol; Disease Models, Animal; Guanethidine; Hypotension,

1987