labetalol has been researched along with Hypertension, Renal in 14 studies
Labetalol: A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.
labetalol : A diastereoisomeric mixture of approximately equal amounts of all four possible stereoisomers ((R,S)-labetolol, (S,R)-labetolol, (S,S)-labetalol and (R,R)-labetalol). It is an adrenergic antagonist used to treat high blood pressure.
2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide : A member of the class of benzamides that is benzamide substituted by a hydroxy group at position 2 and by a 1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl group at position 5.
Hypertension, Renal: Persistent high BLOOD PRESSURE due to KIDNEY DISEASES, such as those involving the renal parenchyma, the renal vasculature, or tumors that secrete RENIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| " It has also been used intravenously in phaeochromocytoma, tetanus, clonidine withdrawal, and as an adjunct to halothane to produce hypotensive anaesthesia." | 4.76 | Combined alpha- and beta-receptor inhibition in the treatment of hypertension. ( Prichard, BN, 1984) |
| "The haemodynamic reaction to an acute emotional stress was tested in nine patients with essential and eleven with renal hypertension after an intravenous bolus of labetalol (0." | 3.66 | [The effect of combined alpha and beta blockade with labetalol on the haemodynamics of stress reaction in hypertensives (author's transl)]. ( Bahlmann, J; Brod, J; Hubrich, W; Pretschner, P, 1980) |
| "Labetalol was 6-10 times less potent than phentolamine in blocking alpha-adrenoreceptors and 1." | 2.35 | A review of the animal pharmacology of labetalol, a combined alpha- and beta-adrenoceptor-blocking drug. ( Brittain, RT; Levy, GP, 1976) |
| "Amosulalol was approximately threefold more potent than labetalol and arotinolol in decreasing blood pressure (BP) in conscious SHR." | 1.29 | Characterization of the adrenoceptor antagonistic and antihypertensive activity of oral amosulalol, a combined alpha- and beta-adrenoceptor antagonist, in hypertensive rats. ( Honda, K; Inagaki, O; Nakagawa, C; Shibasaki, M; Sudoh, K, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (78.57) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Recordati, G | 1 |
| Zorzoli, F | 1 |
| Pontara, O | 1 |
| Turolo, L | 1 |
| Zanchetti, A | 1 |
| Stummvoll, HK | 1 |
| Prichard, BN | 2 |
| Zilcher, H | 1 |
| Weber, H | 1 |
| Glogar, D | 1 |
| Holzer, H | 1 |
| Pogglitsch, H | 1 |
| Katschnig, H | 1 |
| Korthals, C | 1 |
| Gulati, OP | 1 |
| Gulati, N | 1 |
| Krechnáková, A | 1 |
| Danĕková, H | 1 |
| Nandoryová, M | 1 |
| Niederland, TR | 1 |
| Bahlmann, J | 2 |
| Brod, J | 2 |
| Hubrich, W | 2 |
| Pretschner, P | 2 |
| Palla, R | 1 |
| Bionda, A | 1 |
| Carmassi, F | 1 |
| Giusti, R | 1 |
| Marchitiello, M | 1 |
| Inagaki, O | 1 |
| Sudoh, K | 1 |
| Shibasaki, M | 1 |
| Nakagawa, C | 1 |
| Honda, K | 1 |
| Rossi, GP | 1 |
| Zanin, L | 1 |
| Dessì-Fulgheri, P | 1 |
| Savastano, S | 1 |
| Cavazzana, A | 1 |
| Prayer-Galetti, T | 1 |
| Rappelli, A | 1 |
| Pessina, AC | 1 |
| Brittain, RT | 1 |
| Levy, GP | 1 |
| Cachovan, M | 1 |
| Richards, DA | 1 |
2 reviews available for labetalol and Hypertension, Renal
| Article | Year |
|---|---|
Combined alpha- and beta-receptor inhibition in the treatment of hypertension.
Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia; Antihyp | 1984 |
A review of the animal pharmacology of labetalol, a combined alpha- and beta-adrenoceptor-blocking drug.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Autonomic Fibers, Preganglionic; | 1976 |
1 trial available for labetalol and Hypertension, Renal
| Article | Year |
|---|---|
[Combined alpha and beta adrenergic receptor blockade in the treatment of renal hypertension].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Diuretics; Ethanolamines; Humans; Hyperte | 1981 |
11 other studies available for labetalol and Hypertension, Renal
| Article | Year |
|---|---|
Factors influencing acute ischaemia-induced renal hypertension in rats.
Topics: Acute Disease; Animals; Antihypertensive Agents; Biphenyl Compounds; Diuresis; Hematocrit; Hypertens | 2002 |
[Labetalol in ambulatory therapy of hypertension].
Topics: Adult; Aged; Ambulatory Care; Diabetes Mellitus, Type 1; Drug Evaluation; Dyspnea; Ethanolamines; Fe | 1981 |
[Therapy of hypertensive crises with a mono-substance with alpha- and beta-blocking properties (labetalol)].
Topics: Adult; Aged; Ethanolamines; Female; Heart Rate; Humans; Hypertension; Hypertension, Renal; Labetalol | 1981 |
Effects of labetalol in chronic two-kidney Goldblatt hypertension (2-KGH) in rats.
Topics: Animals; Blood Pressure; Chronic Disease; Ethanolamines; Heart; Heart Rate; Hypertension, Renal; Lab | 1980 |
[Labetalol in the treatment of resistant hypertension].
Topics: Ethanolamines; Female; Humans; Hypertension; Hypertension, Renal; Labetalol; Male | 1981 |
[The effect of combined alpha and beta blockade with labetalol on the haemodynamics of stress reaction in hypertensives (author's transl)].
Topics: Adult; Blood Pressure; Cardiac Output; Ethanolamines; Female; Forearm; Heart Rate; Humans; Hypertens | 1980 |
[Effect of treatment with labetalol on renal function in arterial hypertension secondary to parenchymal nephropathy and in essential arterial hypertension].
Topics: Adult; Chronic Disease; Ethanolamines; Glomerulonephritis; Humans; Hypertension; Hypertension, Renal | 1980 |
Characterization of the adrenoceptor antagonistic and antihypertensive activity of oral amosulalol, a combined alpha- and beta-adrenoceptor antagonist, in hypertensive rats.
Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Antihypert | 1994 |
A renin-secreting tumour with severe hypertension and cardiovascular disease: a diagnostic and therapeutic challenge.
Topics: Adult; Cardiovascular Diseases; Gene Expression; Humans; Hypertension, Renal; Kidney Neoplasms; Labe | 1993 |
Effect of an alpha- and beta-adrenoceptor-blocking agent (labetalol) on haemodynamics in hypertension.
Topics: Adult; Blood Pressure; Ethanolamines; Heart Rate; Hemodynamics; Humans; Hypertension; Hypertension, | 1979 |
Labetalol, an alpha- and beta-adrenoceptor-blocking agent: its use in therapeutics. A summary of the symposium.
Topics: Administration, Oral; Anesthesia; Angina Pectoris; Catecholamines; Ethanolamines; Female; Hemodynami | 1979 |