Page last updated: 2024-10-30

labetalol and Hematoma

labetalol has been researched along with Hematoma in 5 studies

Labetalol: A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.
labetalol : A diastereoisomeric mixture of approximately equal amounts of all four possible stereoisomers ((R,S)-labetolol, (S,R)-labetolol, (S,S)-labetalol and (R,R)-labetalol). It is an adrenergic antagonist used to treat high blood pressure.
2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide : A member of the class of benzamides that is benzamide substituted by a hydroxy group at position 2 and by a 1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl group at position 5.

Hematoma: A collection of blood outside the BLOOD VESSELS. Hematoma can be localized in an organ, space, or tissue.

Research Excerpts

ExcerptRelevanceReference
"Blood pressure (BP) reduction after intracerebral hemorrhage (ICH) is controversial, because of concerns that this may cause critical reductions in perihematoma perfusion and thereby precipitate tissue damage."2.79Blood pressure reduction does not reduce perihematoma oxygenation: a CT perfusion study. ( Buck, BH; Butcher, KS; Choi, V; Coutts, SB; Demchuk, AM; Dowlatshahi, D; Emery, DJ; Gould, BE; Hansen, MB; Hill, MD; Kate, MP; McCourt, R; Mouridsen, K; Østergaard, L, 2014)
"We present an unusual case of spinal cord ischemia from an acute type B intramural hematoma that was successfully treated with blood pressure elevation and drainage of cerebral spinal fluid."1.39Acute intramural hematoma of the aorta complicated by spinal cord ischemia. ( Cassiere, HA; Liang, D; Yu, PJ, 2013)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yu, PJ1
Cassiere, HA1
Liang, D1
Kate, MP1
Hansen, MB1
Mouridsen, K1
Østergaard, L1
Choi, V1
Gould, BE1
McCourt, R1
Hill, MD1
Demchuk, AM1
Coutts, SB1
Dowlatshahi, D1
Emery, DJ1
Buck, BH1
Butcher, KS1
Mondel, PK1
Udare, AS1
Anand, S1
Kulkarni, AV1
Kapadia, FN1
Modhe, JM1
Limaye, US1
Koch, S1
Romano, JG1
Forteza, AM1
Otero, CM1
Rabinstein, AA1
Tin, LN1
Mulard, C1
Talon, A1
Garnier, JM1
Lambert, A1
Stroch-Marcy, A1
Kamara, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Clinical Study of the Safety and Efficacy of Analgesia-first Minimal Sedation as an Early Antihypertensive Treatment for Spontaneous Intracerebral Hemorrhage[NCT03207100]338 participants (Actual)Interventional2017-12-06Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for labetalol and Hematoma

ArticleYear
Blood pressure reduction does not reduce perihematoma oxygenation: a CT perfusion study.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:1

    Topics: Aged; Antihypertensive Agents; Blood Pressure; Cerebral Hemorrhage; Female; Hematoma; Humans; Hydral

2014
Rapid blood pressure reduction in acute intracerebral hemorrhage: feasibility and safety.
    Neurocritical care, 2008, Volume: 8, Issue:3

    Topics: Acute Disease; Aged; Antihypertensive Agents; Blood Pressure; Brain Edema; Feasibility Studies; Fema

2008

Other Studies

3 other studies available for labetalol and Hematoma

ArticleYear
Acute intramural hematoma of the aorta complicated by spinal cord ischemia.
    Journal of cardiac surgery, 2013, Volume: 28, Issue:6

    Topics: Acute Disease; Administration, Oral; Adult; Antihypertensive Agents; Aortic Diseases; Blood Pressure

2013
Cerebral hyperperfusion syndrome after endovascular reconstruction of carotid artery in high-flow carotid-jugular fistula.
    Cardiovascular and interventional radiology, 2014, Volume: 37, Issue:5

    Topics: Adult; Angiography, Digital Subtraction; Antihypertensive Agents; Arteriovenous Fistula; Carotid Art

2014
[Subcapsular liver hematoma, a HELLP syndrome complication].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 1994, Volume: 23, Issue:3

    Topics: Adult; Cesarean Section; Combined Modality Therapy; Female; HELLP Syndrome; Hematoma; Humans; Labeta

1994