labetalol has been researched along with HELLP Syndrome in 8 studies
Labetalol: A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.
labetalol : A diastereoisomeric mixture of approximately equal amounts of all four possible stereoisomers ((R,S)-labetolol, (S,R)-labetolol, (S,S)-labetalol and (R,R)-labetalol). It is an adrenergic antagonist used to treat high blood pressure.
2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide : A member of the class of benzamides that is benzamide substituted by a hydroxy group at position 2 and by a 1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl group at position 5.
HELLP Syndrome: A syndrome of HEMOLYSIS, elevated liver ENZYMES, and low blood platelets count (THROMBOCYTOPENIA). HELLP syndrome is observed in pregnant women with PRE-ECLAMPSIA or ECLAMPSIA who also exhibit LIVER damage and abnormalities in BLOOD COAGULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "She also had retinal hemorrhages in both eyes and a hemorrhagic infarct in the left occipital lobe that resulted in a permanent right homonymous hemianopia and a persistently depressed acuity of 20/100 OS." | 1.33 | Permanent visual deficits secondary to the HELLP syndrome. ( Ayazifar, M; Murphy, MA, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arulkumaran, N | 1 |
| Lightstone, L | 1 |
| Gogia, V | 1 |
| Sharma, S | 1 |
| Deka, D | 1 |
| Dadhwal, V | 1 |
| Venkatesh, P | 1 |
| Hamaoui, A | 1 |
| Mercado, R | 1 |
| Ciantar, E | 1 |
| Walker, JJ | 1 |
| Bennett, M | 1 |
| Murphy, MA | 1 |
| Ayazifar, M | 1 |
| Tin, LN | 1 |
| Mulard, C | 1 |
| Talon, A | 1 |
| Garnier, JM | 1 |
| Lambert, A | 1 |
| Stroch-Marcy, A | 1 |
| Kamara, S | 1 |
| Chu, YL | 1 |
| Lin, SY | 1 |
| Lee, PC | 1 |
| Wang, YP | 1 |
| Lee, LH | 1 |
| Liu, CC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Use of Sildenafil Citrate in Management of Mild Pre-eclampsia: A Randomized Controlled Trial[NCT03262961] | Phase 2/Phase 3 | 80 participants (Anticipated) | Interventional | 2016-09-15 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for labetalol and HELLP Syndrome
| Article | Year |
|---|---|
Severe pre-eclampsia and hypertensive crises.
Topics: Administration, Intravenous; Administration, Oral; Antihypertensive Agents; Critical Care; Early Dia | 2013 |
Pre-eclampsia, severe pre-eclampsia and hemolysis, elevated liver enzymes and low platelets syndrome: what is new?
Topics: Anticoagulants; Antihypertensive Agents; Female; HELLP Syndrome; Heparin; Humans; Hypertension, Preg | 2011 |
6 other studies available for labetalol and HELLP Syndrome
| Article | Year |
|---|---|
Bilateral retinal detachment: a clue to diagnosis of HELLP syndrome.
Topics: Administration, Oral; Anticonvulsants; Antihypertensive Agents; Betamethasone; Drug Combinations; Fe | 2014 |
Association of preeclampsia and myasthenia: a case report.
Topics: Antihypertensive Agents; Cesarean Section; Cholinesterase Inhibitors; Female; HELLP Syndrome; Humans | 2009 |
Do not forget about HELLP!
Topics: Abortion, Spontaneous; Adult; Antihypertensive Agents; Eclampsia; Female; HELLP Syndrome; Humans; La | 2011 |
Permanent visual deficits secondary to the HELLP syndrome.
Topics: Adult; Blood Pressure; Brain Infarction; Drug Therapy, Combination; Eclampsia; Female; Furosemide; H | 2005 |
[Subcapsular liver hematoma, a HELLP syndrome complication].
Topics: Adult; Cesarean Section; Combined Modality Therapy; Female; HELLP Syndrome; Hematoma; Humans; Labeta | 1994 |
The role of labetalol and propofol in the management of HELLP syndrome--a case report.
Topics: Adult; Anesthetics, Intravenous; Antihypertensive Agents; Female; HELLP Syndrome; Humans; Labetalol; | 1996 |