labetalol has been researched along with Eclampsia in 22 studies
Labetalol: A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.
labetalol : A diastereoisomeric mixture of approximately equal amounts of all four possible stereoisomers ((R,S)-labetolol, (S,R)-labetolol, (S,S)-labetalol and (R,R)-labetalol). It is an adrenergic antagonist used to treat high blood pressure.
2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide : A member of the class of benzamides that is benzamide substituted by a hydroxy group at position 2 and by a 1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl group at position 5.
Eclampsia: Onset of HYPERREFLEXIA; SEIZURES; or COMA in a previously diagnosed pre-eclamptic patient (PRE-ECLAMPSIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of intravenous infusion of labetalol and of dihydralazine in increasing doses was compared in 12 women with severe hypertension in pregnancy." | 9.05 | Intravenous labetalol and intravenous dihydralazine in severe hypertension in pregnancy. ( Davey, DA; Dommisse, J; Garden, A, 1982) |
| "Labetalol is used to treat hypertensive crisis in women with preeclampsia." | 7.69 | Use of glucagon to treat neonatal low-output congestive heart failure after maternal labetalol therapy. ( Guillet, R; Stevens, TP, 1995) |
| "The effect of intravenous infusion of labetalol and of dihydralazine in increasing doses was compared in 12 women with severe hypertension in pregnancy." | 5.05 | Intravenous labetalol and intravenous dihydralazine in severe hypertension in pregnancy. ( Davey, DA; Dommisse, J; Garden, A, 1982) |
| "Labetalol is used to treat hypertensive crisis in women with preeclampsia." | 3.69 | Use of glucagon to treat neonatal low-output congestive heart failure after maternal labetalol therapy. ( Guillet, R; Stevens, TP, 1995) |
| "Postpartum preeclampsia/eclampsia is the presence of hypertension and proteinuria, with or without seizures, occurring up to 4 weeks after delivery." | 1.37 | Postpartum preeclampsia: emergency department presentation and management. ( Abbott, J; Bakes, K; Withers, E; Yancey, LM, 2011) |
| "Posterior reversible encephalopathy syndrome is a reversible syndrome characterized by headache, seizures, altered mentation, and loss of vision associated with white matter changes on imaging." | 1.35 | Late postpartum preeclampsia with posterior reversible encephalopathy syndrome. ( Kauntia, R; Pandit, VR; Prabhu, MM; Seshadri, S; Valsalan, R, 2009) |
| "She also had retinal hemorrhages in both eyes and a hemorrhagic infarct in the left occipital lobe that resulted in a permanent right homonymous hemianopia and a persistently depressed acuity of 20/100 OS." | 1.33 | Permanent visual deficits secondary to the HELLP syndrome. ( Ayazifar, M; Murphy, MA, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (18.18) | 18.7374 |
| 1990's | 2 (9.09) | 18.2507 |
| 2000's | 7 (31.82) | 29.6817 |
| 2010's | 9 (40.91) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Duan, L | 1 |
| Ng, A | 1 |
| Chen, W | 1 |
| Spencer, HT | 1 |
| Nguyen, J | 1 |
| Shen, AY | 1 |
| Lee, MS | 1 |
| Dong, XY | 1 |
| Bai, CB | 1 |
| Nao, JF | 1 |
| Arulkumaran, N | 1 |
| Lightstone, L | 1 |
| Vadhera, RB | 1 |
| Simon, M | 1 |
| Muthyala, T | 1 |
| Bagga, R | 1 |
| Saha, SC | 1 |
| Saha, PK | 1 |
| Gainder, S | 1 |
| Lal, V | 1 |
| Singh, P | 1 |
| Kaushik, S | 1 |
| Tagg, WG | 1 |
| Razdan, RS | 1 |
| Swain, FR | 1 |
| Gagliardi, JA | 1 |
| Chaddha, SK | 1 |
| Yancey, LM | 1 |
| Withers, E | 1 |
| Bakes, K | 1 |
| Abbott, J | 1 |
| Keating, E | 1 |
| Gonçalves, P | 1 |
| Campos, I | 1 |
| Costa, F | 1 |
| Martel, F | 1 |
| Kauntia, R | 1 |
| Valsalan, R | 1 |
| Seshadri, S | 1 |
| Pandit, VR | 1 |
| Prabhu, MM | 1 |
| Small, KR | 1 |
| Cannava, M | 1 |
| Casey, S | 1 |
| Jacques, J | 1 |
| Seal, SL | 1 |
| Ghosh, D | 1 |
| Kamilya, G | 1 |
| Mukherji, J | 1 |
| Hazra, A | 1 |
| Garain, P | 1 |
| Bennett, M | 1 |
| Newbould, S | 1 |
| Murphy, MA | 1 |
| Ayazifar, M | 1 |
| Belfort, MA | 1 |
| Clark, SL | 1 |
| Sibai, B | 1 |
| Omu, AE | 1 |
| Al-Harmi, J | 1 |
| Vedi, HL | 1 |
| Mlechkova, L | 1 |
| Sayed, AF | 1 |
| Al-Ragum, NS | 1 |
| Ram, CV | 2 |
| Garden, A | 1 |
| Davey, DA | 1 |
| Dommisse, J | 1 |
| Stevens, TP | 1 |
| Guillet, R | 1 |
| Bhorat, IE | 1 |
| Naidoo, DP | 1 |
| Rout, CC | 1 |
| Moodley, J | 1 |
| Michael, CA | 1 |
| Meese, RB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Use of Sildenafil Citrate in Management of Mild Pre-eclampsia: A Randomized Controlled Trial[NCT03262961] | Phase 2/Phase 3 | 80 participants (Anticipated) | Interventional | 2016-09-15 | Recruiting | ||
| Folic Acid Clinical Trial: Follow up of Children (FACT 4 Child)[NCT03269110] | 2,578 participants (Anticipated) | Observational | 2017-07-01 | Enrolling by invitation | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for labetalol and Eclampsia
| Article | Year |
|---|---|
Severe pre-eclampsia and hypertensive crises.
Topics: Administration, Intravenous; Administration, Oral; Antihypertensive Agents; Critical Care; Early Dia | 2013 |
Hypertensive emergencies in pregnancy.
Topics: Antihypertensive Agents; Eclampsia; Emergencies; Female; Humans; Hydralazine; Hypertension; Hyperten | 2014 |
Posterior reversible encephalopathy syndrome following a cesarean delivery: case report and literature review.
Topics: Adult; Anticonvulsants; Antihypertensive Agents; Cesarean Section; Eclampsia; Female; Humans; Hypert | 2008 |
Cerebral hemodynamics in preeclampsia: cerebral perfusion and the rationale for an alternative to magnesium sulfate.
Topics: Anticonvulsants; Antihypertensive Agents; Cerebrovascular Circulation; Eclampsia; Female; Humans; La | 2006 |
Hypertensive crisis.
Topics: Antihypertensive Agents; Brain Diseases; Cerebrovascular Disorders; Clonidine; Coronary Disease; Dia | 1984 |
Hypertensive cardiovascular emergencies.
Topics: Antihypertensive Agents; Brain Diseases; Cerebrovascular Disorders; Clonidine; Coronary Disease; Dia | 1985 |
3 trials available for labetalol and Eclampsia
| Article | Year |
|---|---|
Does route of delivery affect maternal and perinatal outcome in women with eclampsia? A randomized controlled pilot study.
Topics: Adult; Anticonvulsants; Antihypertensive Agents; Apgar Score; Cesarean Section; Critical Care; Eclam | 2012 |
Intravenous labetalol and intravenous dihydralazine in severe hypertension in pregnancy.
Topics: Adult; Blood Pressure; Dihydralazine; Eclampsia; Ethanolamines; Female; Fetus; Humans; Hydralazine; | 1982 |
Malignant ventricular arrhythmias in eclampsia: a comparison of labetalol with dihydralazine.
Topics: Adolescent; Adult; Dihydralazine; Eclampsia; Electrocardiography, Ambulatory; Female; Humans; Infusi | 1993 |
13 other studies available for labetalol and Eclampsia
| Article | Year |
|---|---|
β-Blocker Exposure in Pregnancy and Risk of Fetal Cardiac Anomalies.
Topics: Adrenergic beta-Antagonists; Age Factors; Arrhythmias, Cardiac; Atenolol; Body Mass Index; Californi | 2017 |
Clinical and radiological features of posterior reversible encephalopathy syndrome in patients with pre-eclampsia and eclampsia.
Topics: Adult; Anticonvulsants; Antihypertensive Agents; Brain; Diazepam; Eclampsia; Female; Humans; Labetal | 2017 |
Isolated oculomotor nerve palsy with complete recovery in eclampsia: A rare presentation.
Topics: Adult; Anticonvulsants; Antihypertensive Agents; Brain; Diagnostic Techniques, Ophthalmological; Ecl | 2016 |
Postpartum preeclampsia: emergency department presentation and management.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Antihypertensive Agents; Benzodiazepines; E | 2011 |
Folic acid uptake by the human syncytiotrophoblast: interference by pharmacotherapy, drugs of abuse and pathological conditions.
Topics: Amphetamine; Antihypertensive Agents; Atenolol; Biological Transport; Cell Survival; Cells, Cultured | 2009 |
Late postpartum preeclampsia with posterior reversible encephalopathy syndrome.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Amlodipine; Antihypertensive Agent | 2009 |
Tonic-clonic seizures in a postpartum patient: case report.
Topics: Adult; Analgesics; Antihypertensive Agents; Diagnosis, Differential; Eclampsia; Epilepsy, Tonic-Clon | 2010 |
Do not forget about HELLP!
Topics: Abortion, Spontaneous; Adult; Antihypertensive Agents; Eclampsia; Female; HELLP Syndrome; Humans; La | 2011 |
Postpartum eclampsia.
Topics: Adult; Anticonvulsants; Antihypertensive Agents; Diagnosis, Differential; Eclampsia; Female; Humans; | 2002 |
Permanent visual deficits secondary to the HELLP syndrome.
Topics: Adult; Blood Pressure; Brain Infarction; Drug Therapy, Combination; Eclampsia; Female; Furosemide; H | 2005 |
Magnesium sulphate therapy in women with pre-eclampsia and eclampsia in Kuwait.
Topics: Adult; Antihypertensive Agents; Calcium Channel Blockers; Drug Therapy, Combination; Eclampsia; Fema | 2008 |
Use of glucagon to treat neonatal low-output congestive heart failure after maternal labetalol therapy.
Topics: Adult; Eclampsia; Female; Glucagon; Heart Failure; Humans; Infant, Newborn; Infant, Newborn, Disease | 1995 |
The treatment of hypertension in pregnancy.
Topics: Adolescent; Adult; Anticonvulsants; Antihypertensive Agents; Bethanidine; Eclampsia; Female; Humans; | 1978 |