Page last updated: 2024-10-30

labetalol and Delayed Effects, Prenatal Exposure

labetalol has been researched along with Delayed Effects, Prenatal Exposure in 7 studies

Labetalol: A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.
labetalol : A diastereoisomeric mixture of approximately equal amounts of all four possible stereoisomers ((R,S)-labetolol, (S,R)-labetolol, (S,S)-labetalol and (R,R)-labetalol). It is an adrenergic antagonist used to treat high blood pressure.
2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide : A member of the class of benzamides that is benzamide substituted by a hydroxy group at position 2 and by a 1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl group at position 5.

Research Excerpts

ExcerptRelevanceReference
"Hypotension is more common after maternal labetalol exposure, regardless of the dosage and route of administration."5.38Neonatal side effects of maternal labetalol treatment in severe preeclampsia. ( Heida, KY; Hulzebos, CV; Van Veen, TR; Zeeman, GG, 2012)
"Nine mothers were treated with labetalol and/or MgSO4 during pregnancy, three mothers with labetalol, MgSO4 and nifedipine, and 19 mothers with nifedipine only."3.79Maternal antihypertensive drugs may influence cerebral oxygen extraction in preterm infants during the first days after birth. ( Bos, AF; Kooi, EM; van den Berg, PP; Verhagen, EA, 2013)
"To determine the functional development of children born after treatment of mild-to-moderate gestational hypertension with labetalol versus methyldopa, and no antihypertensive treatment."3.76Antihypertensive treatment during pregnancy and functional development at primary school age in a historical cohort study. ( Eskes, TK; Gabreëls, FJ; Pasker-de Jong, PC; Pellegrino, A; van Gelder, MM; Zielhuis, GA, 2010)
"Two infants with features of severe beta adrenergic blockade, pericardial effusions, and myocardial hypertrophy were born to mothers receiving long term treatment with oral labetalol for hypertension in pregnancy."3.70Adverse neonatal effects of maternal labetalol treatment. ( Crooks, BN; Deshpande, SA; Hall, C; Milligan, DW; Platt, MP, 1998)
"Hypotension is more common after maternal labetalol exposure, regardless of the dosage and route of administration."1.38Neonatal side effects of maternal labetalol treatment in severe preeclampsia. ( Heida, KY; Hulzebos, CV; Van Veen, TR; Zeeman, GG, 2012)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's6 (85.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Thewissen, L1
Pistorius, L1
Baerts, W1
Naulaers, G1
Van Bel, F1
Lemmers, P1
Pasker-de Jong, PC1
Zielhuis, GA1
van Gelder, MM1
Pellegrino, A1
Gabreëls, FJ1
Eskes, TK1
Chan, WS1
Koren, G1
Barrera, M1
Rezvani, M1
Knittel-Keren, D1
Nulman, I1
Heida, KY1
Zeeman, GG1
Van Veen, TR1
Hulzebos, CV1
Daskas, N1
Crowne, E1
Shield, JP1
Verhagen, EA1
Kooi, EM1
van den Berg, PP1
Bos, AF1
Crooks, BN1
Deshpande, SA1
Hall, C1
Platt, MP1
Milligan, DW1

Other Studies

7 other studies available for labetalol and Delayed Effects, Prenatal Exposure

ArticleYear
Neonatal haemodynamic effects following foetal exposure to labetalol in hypertensive disorders of pregnancy.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2017, Volume: 30, Issue:13

    Topics: Antihypertensive Agents; Blood Pressure; Case-Control Studies; Cerebrum; Female; Gestational Age; He

2017
Antihypertensive treatment during pregnancy and functional development at primary school age in a historical cohort study.
    BJOG : an international journal of obstetrics and gynaecology, 2010, Volume: 117, Issue:9

    Topics: Antihypertensive Agents; Attention; Attention Deficit Disorder with Hyperactivity; Bed Rest; Child;

2010
Neurocognitive development of children following in-utero exposure to labetalol for maternal hypertension: a cohort study using a prospectively collected database.
    Hypertension in pregnancy, 2010, Volume: 29, Issue:3

    Topics: Adult; Analysis of Variance; Child; Child Development; Child, Preschool; Databases, Factual; Female;

2010
Neonatal side effects of maternal labetalol treatment in severe preeclampsia.
    Early human development, 2012, Volume: 88, Issue:7

    Topics: Adult; Antihypertensive Agents; Case-Control Studies; Female; Fetal Death; Humans; Infant Mortality;

2012
Is labetalol really a culprit in neonatal hypoglycaemia?
    Archives of disease in childhood. Fetal and neonatal edition, 2013, Volume: 98, Issue:2

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Female; Humans; Hypertension; Hypoglycemia; In

2013
Maternal antihypertensive drugs may influence cerebral oxygen extraction in preterm infants during the first days after birth.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2013, Volume: 26, Issue:9

    Topics: Antihypertensive Agents; Case-Control Studies; Cerebral Cortex; Cerebrovascular Circulation; Female;

2013
Adverse neonatal effects of maternal labetalol treatment.
    Archives of disease in childhood. Fetal and neonatal edition, 1998, Volume: 79, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Cardiomegaly; Dobutamine; Dopamine; Dr

1998