labetalol has been researched along with Complication, Intraoperative in 13 studies
Labetalol: A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.
labetalol : A diastereoisomeric mixture of approximately equal amounts of all four possible stereoisomers ((R,S)-labetolol, (S,R)-labetolol, (S,S)-labetalol and (R,R)-labetalol). It is an adrenergic antagonist used to treat high blood pressure.
2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide : A member of the class of benzamides that is benzamide substituted by a hydroxy group at position 2 and by a 1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The number of patients with intraoperative hypertension, number of patients receiving SNP, dose of SNP administered, and number of hypertension episodes were significantly lower in patients who received labetalol pretreatment than in control patients." | 9.12 | Labetalol pretreatment reduces blood pressure instability during surgical resection of pheochromocytoma. ( Chung, PC; Hsieh, JR; Li, AH; Ng, YT; Yang, MW, 2006) |
| " esmolol and labetalol in the treatment of perioperative hypertension in ambulatory surgery." | 9.07 | A comparison of esmolol and labetalol for the treatment of perioperative hypertension in geriatric ambulatory surgical patients. ( Dimich, I; Sampson, I; Singh, PP; Sonnenklar, N, 1992) |
| " During the first 60 min of bypass, hypotension (40-45 mm Hg) was observed in spite of phenylephrine 14 mg." | 7.67 | Bronchospasm and hypotension during cardiopulmonary bypass after preoperative cimetidine and labetalol therapy. ( Durant, PA; Joucken, K, 1984) |
| "The number of patients with intraoperative hypertension, number of patients receiving SNP, dose of SNP administered, and number of hypertension episodes were significantly lower in patients who received labetalol pretreatment than in control patients." | 5.12 | Labetalol pretreatment reduces blood pressure instability during surgical resection of pheochromocytoma. ( Chung, PC; Hsieh, JR; Li, AH; Ng, YT; Yang, MW, 2006) |
| " esmolol and labetalol in the treatment of perioperative hypertension in ambulatory surgery." | 5.07 | A comparison of esmolol and labetalol for the treatment of perioperative hypertension in geriatric ambulatory surgical patients. ( Dimich, I; Sampson, I; Singh, PP; Sonnenklar, N, 1992) |
| "We report the specifics of 12 cases of severe hypertension after the intraoperative use of topical phenylephrine, submucosal epinephrine, or both." | 4.79 | Cardiopulmonary compromise after use of topical and submucosal alpha-agonists: possible added complication by the use of beta-blocker therapy. ( Carpenter, RL; Guertin, SR; Kalyanaraman, M; McGlew, MJ, 1997) |
| "To evaluate the effect on arterial blood pressure (ABP) of labetalol infusion as treatment for perioperative non nociceptive acute hypertension in dogs." | 3.96 | Retrospective evaluation of labetalol as antihypertensive agent in dogs. ( Corletto, F; De Gennaro, C; Zublena, F, 2020) |
| "An increase in blood pressure, accompanied by atrial fibrillation, agitation, incomprehensible shouts and loss of consciousness, was observed in an elderly, ASA classification group II, cardiovascularly medicated male, 12 min after performance of axillary block with mepivacaine 850 mg containing adrenaline 0." | 3.70 | An unusual toxic reaction to axillary block by mepivacaine with adrenaline. ( Koscielniak-Nielsen, ZJ, 1998) |
| " During the first 60 min of bypass, hypotension (40-45 mm Hg) was observed in spite of phenylephrine 14 mg." | 3.67 | Bronchospasm and hypotension during cardiopulmonary bypass after preoperative cimetidine and labetalol therapy. ( Durant, PA; Joucken, K, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (30.77) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Zublena, F | 1 |
| De Gennaro, C | 1 |
| Corletto, F | 1 |
| Yoon, SW | 1 |
| Choi, GJ | 1 |
| Seong, HK | 1 |
| Lee, MJ | 1 |
| Kang, H | 1 |
| Asencio Moreno, A | 1 |
| Alamán Orbañanos, B | 1 |
| Moro Velasco, MC | 1 |
| Chung, PC | 1 |
| Ng, YT | 1 |
| Hsieh, JR | 1 |
| Yang, MW | 1 |
| Li, AH | 1 |
| Calotti, F | 1 |
| Steen, D | 1 |
| Durant, PA | 1 |
| Joucken, K | 1 |
| Lüben, V | 1 |
| Rieder, W | 1 |
| Zierski, J | 1 |
| Hempelmann, G | 1 |
| Kalyanaraman, M | 1 |
| Carpenter, RL | 1 |
| McGlew, MJ | 1 |
| Guertin, SR | 1 |
| Koscielniak-Nielsen, ZJ | 1 |
| Vallejo, R | 1 |
| DeSouza, G | 1 |
| Lee, J | 1 |
| Singh, PP | 1 |
| Dimich, I | 1 |
| Sampson, I | 1 |
| Sonnenklar, N | 1 |
| Sheikh, A | 1 |
| Carrasco, MS | 1 |
| Iribarren, MJ | 1 |
| Torres, LM | 1 |
| Esteban, J | 1 |
| Cobo, I | 1 |
| De Castro, J | 1 |
| Arroyo, JL | 1 |
1 review available for labetalol and Complication, Intraoperative
| Article | Year |
|---|---|
Cardiopulmonary compromise after use of topical and submucosal alpha-agonists: possible added complication by the use of beta-blocker therapy.
Topics: Administration, Intranasal; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Child; Epinephri | 1997 |
2 trials available for labetalol and Complication, Intraoperative
| Article | Year |
|---|---|
Labetalol pretreatment reduces blood pressure instability during surgical resection of pheochromocytoma.
Topics: Adult; Antihypertensive Agents; Drug Therapy, Combination; Female; Humans; Hypertension; Infusions, | 2006 |
A comparison of esmolol and labetalol for the treatment of perioperative hypertension in geriatric ambulatory surgical patients.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Analysis of Va | 1992 |
10 other studies available for labetalol and Complication, Intraoperative
| Article | Year |
|---|---|
Retrospective evaluation of labetalol as antihypertensive agent in dogs.
Topics: Adrenalectomy; Animals; Antihypertensive Agents; Craniotomy; Dogs; Heart Rate; Hypertension; Intraop | 2020 |
Pharmacological strategies to prevent haemodynamic changes after intubation in parturient women with hypertensive disorders of pregnancy: A network meta-analysis.
Topics: Anesthesia, General; Antihypertensive Agents; Apgar Score; Blood Pressure; Blood Pressure Determinat | 2021 |
[Anesthesia for the surgical removal of bilateral pheochromocytomas during the second trimester of pregnancy].
Topics: Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Adult; Anesthesia, Epidural; Anesthesia, Gene | 2009 |
Labetalol causing intraoperative floppy-iris syndrome.
Topics: Adrenergic alpha-Antagonists; Humans; Intraoperative Complications; Iris; Iris Diseases; Labetalol; | 2007 |
Bronchospasm and hypotension during cardiopulmonary bypass after preoperative cimetidine and labetalol therapy.
Topics: Bronchial Spasm; Cardiopulmonary Bypass; Cimetidine; Drug Interactions; Humans; Hypotension; Intraop | 1984 |
[Labetalol for the management of hypertensive crises during surgery of cerebral aneurysm; a haemodynamic study (author's transl)].
Topics: Adolescent; Adult; Blood Pressure; Ethanolamines; Heart Rate; Hemodynamics; Humans; Hypertension; Hy | 1981 |
An unusual toxic reaction to axillary block by mepivacaine with adrenaline.
Topics: Absorption; Aged; Akathisia, Drug-Induced; Anesthetics, Local; Anti-Arrhythmia Agents; Antihypertens | 1998 |
Shy-Drager syndrome and severe unexplained intraoperative hypotension responsive to vasopressin.
Topics: Adrenergic beta-Antagonists; Aged; Hemodynamics; Humans; Hypotension; Intraoperative Complications; | 2002 |
Use of atracurium and labetalol in a patient with phaeochromocytoma.
Topics: Adrenal Gland Neoplasms; Adult; Atracurium; Female; Humans; Hypertension; Intraoperative Complicatio | 1986 |
[A new technic for protection in surgical stress].
Topics: Adult; Alfentanil; Ethanolamines; Female; Fentanyl; Humans; Intraoperative Complications; Labetalol; | 1985 |