Page last updated: 2024-10-30

labetalol and Cocaine-Related Disorders

labetalol has been researched along with Cocaine-Related Disorders in 4 studies

Labetalol: A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.
labetalol : A diastereoisomeric mixture of approximately equal amounts of all four possible stereoisomers ((R,S)-labetolol, (S,R)-labetolol, (S,S)-labetalol and (R,R)-labetalol). It is an adrenergic antagonist used to treat high blood pressure.
2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide : A member of the class of benzamides that is benzamide substituted by a hydroxy group at position 2 and by a 1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl group at position 5.

Cocaine-Related Disorders: Disorders related or resulting from use of cocaine.

Research Excerpts

ExcerptRelevanceReference
"Labetalol treatment significantly attenuated the cocaine-induced increases in heart rate and systolic blood pressure."2.69Effects of labetalol treatment on the physiological and subjective response to smoked cocaine. ( Babb, DA; Brown, S; Hatsukami, DK; Pentel, PR; Sofuoglu, M, 2000)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Richards, JR2
Lange, RA2
Arnold, TC1
Horowitz, BZ1
Hoskins, MH1
Leleiko, RM1
Ramos, JJ1
Sola, S1
Caneer, PM1
Khan, BV1
Sofuoglu, M1
Brown, S1
Babb, DA1
Pentel, PR1
Hatsukami, DK1

Trials

1 trial available for labetalol and Cocaine-Related Disorders

ArticleYear
Effects of labetalol treatment on the physiological and subjective response to smoked cocaine.
    Pharmacology, biochemistry, and behavior, 2000, Volume: 65, Issue:2

    Topics: Adrenergic Antagonists; Behavior, Addictive; Blood Pressure; Cocaine; Cocaine-Related Disorders; Cra

2000

Other Studies

3 other studies available for labetalol and Cocaine-Related Disorders

ArticleYear
Labetalol and cardiovascular consequences of cocaine use.
    Trends in cardiovascular medicine, 2016, Volume: 26, Issue:2

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Cardiovascular Diseases; Cocaine; Cocaine-Related Diso

2016
Dual cocaine and methamphetamine cardiovascular toxicity: rapid resolution with labetalol.
    The American journal of emergency medicine, 2017, Volume: 35, Issue:3

    Topics: Administration, Intravenous; Adrenergic beta-Antagonists; Amphetamine-Related Disorders; Anti-Anxiet

2017
Effects of labetalol on hemodynamic parameters and soluble biomarkers of inflammation in acute coronary syndrome in patients with active cocaine use.
    Journal of cardiovascular pharmacology and therapeutics, 2010, Volume: 15, Issue:1

    Topics: Acute Coronary Syndrome; Adrenergic alpha-Antagonists; Adult; Aged; Biomarkers; Cardiovascular Agent

2010