Page last updated: 2024-10-30

labetalol and Brain Neoplasms

labetalol has been researched along with Brain Neoplasms in 3 studies

Labetalol: A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.
labetalol : A diastereoisomeric mixture of approximately equal amounts of all four possible stereoisomers ((R,S)-labetolol, (S,R)-labetolol, (S,S)-labetalol and (R,R)-labetalol). It is an adrenergic antagonist used to treat high blood pressure.
2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide : A member of the class of benzamides that is benzamide substituted by a hydroxy group at position 2 and by a 1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl group at position 5.

Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.

Research Excerpts

ExcerptRelevanceReference
"We compared the efficacy of the combination of enalaprilat/labetalol with that of enalaprilat/nicardipine to prevent emergence postcraniotomy hypertension."9.09A comparative study between a calcium channel blocker (Nicardipine) and a combined alpha-beta-blocker (Labetalol) for the control of emergence hypertension during craniotomy for tumor surgery. ( Broad, C; Ferri, E; Kross, RA; Leung, D; Melendez, JA; Pratila, M; Veronesi, M, 2000)
"We compared the efficacy of the combination of enalaprilat/labetalol with that of enalaprilat/nicardipine to prevent emergence postcraniotomy hypertension."5.09A comparative study between a calcium channel blocker (Nicardipine) and a combined alpha-beta-blocker (Labetalol) for the control of emergence hypertension during craniotomy for tumor surgery. ( Broad, C; Ferri, E; Kross, RA; Leung, D; Melendez, JA; Pratila, M; Veronesi, M, 2000)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Montolivo, M2
Gemma, M2
Regi, B2
Coffano, B1
Giannini, A1
Grandi, L1
Fiacchino, F2
Kross, RA1
Ferri, E1
Leung, D1
Pratila, M1
Broad, C1
Veronesi, M1
Melendez, JA1
Pastore, JC1
Bricchi, M1
Vescovi, A1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficiency of Intravenous Lidocaine to Reduce Coughing and the Hemodynamic Changes Associated to Tracheal Extubation[NCT03731429]Phase 4144 participants (Anticipated)Interventional2019-04-05Recruiting
Nicardipine Versus Esmolol for Management of Emergence Hypertension After Craniotomy[NCT01951950]Phase 140 participants (Actual)Interventional2013-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Failure of Drug to Control Systolic Blood Pressure (SBP) < 140 mmHg

(NCT01951950)
Timeframe: 1 hour postoperatively

Interventionparticipants (Number)
Nicardipine1
Esmolol11

Trials

1 trial available for labetalol and Brain Neoplasms

ArticleYear
A comparative study between a calcium channel blocker (Nicardipine) and a combined alpha-beta-blocker (Labetalol) for the control of emergence hypertension during craniotomy for tumor surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Anesth

2000
A comparative study between a calcium channel blocker (Nicardipine) and a combined alpha-beta-blocker (Labetalol) for the control of emergence hypertension during craniotomy for tumor surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Anesth

2000
A comparative study between a calcium channel blocker (Nicardipine) and a combined alpha-beta-blocker (Labetalol) for the control of emergence hypertension during craniotomy for tumor surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Anesth

2000
A comparative study between a calcium channel blocker (Nicardipine) and a combined alpha-beta-blocker (Labetalol) for the control of emergence hypertension during craniotomy for tumor surgery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Anesth

2000

Other Studies

2 other studies available for labetalol and Brain Neoplasms

ArticleYear
Labetalol as prophylaxis of cardiovascular instability after cerebral angioma surgery.
    Minerva anestesiologica, 1993, Volume: 59, Issue:12

    Topics: Brain Neoplasms; Epinephrine; Hemangioma; Humans; Hypertension; Labetalol; Norepinephrine; Postopera

1993
[Labetalol in the prophylaxis of postoperative arterial hypertension in surgery of the posterior cranial fossa].
    Minerva anestesiologica, 1992, Volume: 58, Issue:4 Suppl 1

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Cranial Fossa, Posterior; Female; Humans; Hypertension; La

1992