labetalol has been researched along with Brain Edema in 3 studies
Labetalol: A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.
labetalol : A diastereoisomeric mixture of approximately equal amounts of all four possible stereoisomers ((R,S)-labetolol, (S,R)-labetolol, (S,S)-labetalol and (R,R)-labetalol). It is an adrenergic antagonist used to treat high blood pressure.
2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide : A member of the class of benzamides that is benzamide substituted by a hydroxy group at position 2 and by a 1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl group at position 5.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of induced hypotension with isoflurane and labetalol on cerebral edema formation were compared following a cryogenic brain injury in dogs." | 9.07 | Cerebral edema formation in dogs following hypotension induced with isoflurane and labetalol. ( Bendo, AA; Capuano, C; Cottrell, JE; Kozlowski, PB; Mendeszoon, MH, 1993) |
| "The effects of induced hypotension with isoflurane and labetalol on cerebral edema formation were compared following a cryogenic brain injury in dogs." | 5.07 | Cerebral edema formation in dogs following hypotension induced with isoflurane and labetalol. ( Bendo, AA; Capuano, C; Cottrell, JE; Kozlowski, PB; Mendeszoon, MH, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jones, R | 1 |
| Redler, K | 1 |
| Witherick, J | 1 |
| Fuller, G | 1 |
| Mahajan, T | 1 |
| Wakerley, BR | 1 |
| Koch, S | 1 |
| Romano, JG | 1 |
| Forteza, AM | 1 |
| Otero, CM | 1 |
| Rabinstein, AA | 1 |
| Bendo, AA | 1 |
| Kozlowski, PB | 1 |
| Capuano, C | 1 |
| Cottrell, JE | 1 |
| Mendeszoon, MH | 1 |
2 trials available for labetalol and Brain Edema
| Article | Year |
|---|---|
Rapid blood pressure reduction in acute intracerebral hemorrhage: feasibility and safety.
Topics: Acute Disease; Aged; Antihypertensive Agents; Blood Pressure; Brain Edema; Feasibility Studies; Fema | 2008 |
Cerebral edema formation in dogs following hypotension induced with isoflurane and labetalol.
Topics: Animals; Brain; Brain Edema; Brain Injuries; Dogs; Hypotension; Isoflurane; Labetalol; Male | 1993 |
1 other study available for labetalol and Brain Edema
| Article | Year |
|---|---|
Posterior reversible encephalopathy syndrome complicating diabetic ketoacidosis; an important treatable complication.
Topics: Adolescent; Blindness, Cortical; Brain Edema; Diabetic Ketoacidosis; Electrolytes; Female; Fluid The | 2017 |