labetalol has been researched along with Angor Pectoris in 34 studies
Labetalol: A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.
labetalol : A diastereoisomeric mixture of approximately equal amounts of all four possible stereoisomers ((R,S)-labetolol, (S,R)-labetolol, (S,S)-labetalol and (R,R)-labetalol). It is an adrenergic antagonist used to treat high blood pressure.
2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide : A member of the class of benzamides that is benzamide substituted by a hydroxy group at position 2 and by a 1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present review shows that labetalol has many advantageous properties in the treatment of patients suffering from angina pectoris with or without hypertension." | 10.16 | Labetalol in the treatment of angina pectoris. ( Kanto, JH, 1987) |
| " A multi-center, double-blind, parallel group study compared the safety and efficacy of labetalol to propranolol in the treatment of patients with both exertional angina and mild to moderate systemic hypertension." | 9.06 | Labetalol compared with propranolol in patients with both angina pectoris and systemic hypertension: a double-blind study. ( Charlap, S; Frishman, WH; Shapiro, W, 1989) |
| "Labetalol, a combined alpha- and beta-receptor antagonist, was compared with nifedipine in a placebo-controlled, randomized double-blind cross over study (four week treatment periods) of 11 normotensive patients with stable exertional angina pectoris." | 9.06 | Labetalol in the treatment of stable exertional angina pectoris: a comparison with nifedipine. ( Crake, T; Fox, K; Mulcahy, D; Wright, C, 1988) |
| "Labetalol (Trandate; Allen & Hanbury) was administered to 17 hypertensive patients with angina pectoris, which had persisted despite blood pressure control on treatment including beta-blocking agents." | 9.05 | Beneficial effect of labetalol in hypertensive patients with angina pectoris. ( Lubbe, WF; White, DA, 1983) |
| "The effects of a combined alpha and beta receptor antagonist, labetalol, were investigated in 10 patients with chronic stable angina pectoris." | 9.05 | Effects of combined alpha and beta adrenoceptor blockade in patients with angina pectoris. A double blind study comparing labetalol with placebo. ( Fox, KM; Mockus, L; Quyyumi, AA; Shackell, M; Sutton, GC; Wright, C, 1985) |
| "The efficacy of labetalol, an alpha and beta receptor antagonist, was evaluated in 12 normotensive patients with stable angina pectoris in a single blind dose ranging study." | 9.05 | Oral labetalol in the management of stable angina pectoris in normotensive patients. ( Akhras, F; Jackson, G; Upward, JW, 1985) |
| " Eight hypertensive patients with angina pectoris had placebo added to their existing medications for 8 weeks, then incremental doses of active labetalol with simultaneous stepwise reduction in other medicines until blood pressure was satisfactorily controlled; after that only labetalol and thiazide (8 weeks) and finally labetalol-placebo together with previous beta-adrenoreceptor antagonists and thiazide for 4 weeks were administered." | 9.04 | Labetalol in hypertensive patients with angina pectoris: beneficial effect of combined alpha- and beta-adrenoreceptor blockade. ( Lubbe, WF; White, DA, 1978) |
| "The systemic and coronary hemodynamic effects of combined alpha- and beta-adrenergic blockade produced by labetalol were assessed in 12 normotensive patients with angina pectoris and an ischemic electrocardiographic response to exercise stress." | 7.67 | Systemic and coronary hemodynamic effects of combined alpha- and beta-adrenergic blockade (labetalol) in normotensive patients with stable angina pectoris and positive exercise stress test responses. ( Feldman, RL; Hill, JA; Prida, XE, 1987) |
| "The systemic and coronary hemodynamic effects of combined alpha- and beta-adrenergic blockade produced by oral labetalol were assessed in 12 normotensive patients with angina pectoris and an ischemic electrocardiographic response to exercise stress." | 7.67 | Systemic and coronary hemodynamic effects of combined oral alpha- and beta-adrenergic blockade (labetalol) in normotensive patients with stable angina pectoris and positive exercise stress tests. ( Feldman, RL; Hill, JA; Prida, XE, 1988) |
| "1 In nine hypertensive subjects with angina pectoris, labetalol diminished the incidence of chest pain occurring spontaneously or induced by exercise." | 7.66 | Open evaluation of labetalol in the treatment of angina pectoris occurring in hypertensive patients. ( Besterman, EM; Spencer, M, 1979) |
| "Labetalol and atenolol were equivalent in control of blood pressure at rest, exercise tolerance and use of nitroglycerin; however, heart rates at rest and during exercise were higher with labetalol (p less than 0." | 6.66 | Double-blind trial comparing labetalol with atenolol in the treatment of systemic hypertension with angina pectoris. ( Jee, LD; Opie, LH, 1985) |
| "Thus labetalol would appear to be an effective antianginal agent." | 6.37 | Labetalol in normotensive patients with angina pectoris. ( Fox, K; Quyyumi, AA, 1988) |
| "The present review shows that labetalol has many advantageous properties in the treatment of patients suffering from angina pectoris with or without hypertension." | 6.16 | Labetalol in the treatment of angina pectoris. ( Kanto, JH, 1987) |
| "This is the first reported large clinical trial of the antianginal and acute ischemic effectiveness and safety of dilevalol (the R, R-isomer of labetalol) in patients with chronic stable angina pectoris." | 5.06 | The efficacy and safety of dilevalol in patients with chronic stable angina pectoris. ( Bennett, WT; Bittar, N; Glasser, SP; Kinhal, V; Koehn, DK, 1989) |
| " A multi-center, double-blind, parallel group study compared the safety and efficacy of labetalol to propranolol in the treatment of patients with both exertional angina and mild to moderate systemic hypertension." | 5.06 | Labetalol compared with propranolol in patients with both angina pectoris and systemic hypertension: a double-blind study. ( Charlap, S; Frishman, WH; Shapiro, W, 1989) |
| "Labetalol, a combined alpha- and beta-receptor antagonist, was compared with nifedipine in a placebo-controlled, randomized double-blind cross over study (four week treatment periods) of 11 normotensive patients with stable exertional angina pectoris." | 5.06 | Labetalol in the treatment of stable exertional angina pectoris: a comparison with nifedipine. ( Crake, T; Fox, K; Mulcahy, D; Wright, C, 1988) |
| "Labetalol (Trandate; Allen & Hanbury) was administered to 17 hypertensive patients with angina pectoris, which had persisted despite blood pressure control on treatment including beta-blocking agents." | 5.05 | Beneficial effect of labetalol in hypertensive patients with angina pectoris. ( Lubbe, WF; White, DA, 1983) |
| "The bicycle exercise tolerance was studied in ten patients with angina pectoris after one week's treatment with an alpha-beta-blocker (labetalol 300 mg b." | 5.05 | Relation between ST-depression and chest pain in patients with coronary heart disease receiving no treatment and after beta-blockade and combined alpha-beta-blockade. ( Bjurö, T; Hagman, M; Nyberg, G; Smith, U, 1981) |
| "The effects of a combined alpha and beta receptor antagonist, labetalol, were investigated in 10 patients with chronic stable angina pectoris." | 5.05 | Effects of combined alpha and beta adrenoceptor blockade in patients with angina pectoris. A double blind study comparing labetalol with placebo. ( Fox, KM; Mockus, L; Quyyumi, AA; Shackell, M; Sutton, GC; Wright, C, 1985) |
| "The efficacy of labetalol, an alpha and beta receptor antagonist, was evaluated in 12 normotensive patients with stable angina pectoris in a single blind dose ranging study." | 5.05 | Oral labetalol in the management of stable angina pectoris in normotensive patients. ( Akhras, F; Jackson, G; Upward, JW, 1985) |
| " Eight hypertensive patients with angina pectoris had placebo added to their existing medications for 8 weeks, then incremental doses of active labetalol with simultaneous stepwise reduction in other medicines until blood pressure was satisfactorily controlled; after that only labetalol and thiazide (8 weeks) and finally labetalol-placebo together with previous beta-adrenoreceptor antagonists and thiazide for 4 weeks were administered." | 5.04 | Labetalol in hypertensive patients with angina pectoris: beneficial effect of combined alpha- and beta-adrenoreceptor blockade. ( Lubbe, WF; White, DA, 1978) |
| "The systemic and coronary hemodynamic effects of combined alpha- and beta-adrenergic blockade produced by labetalol were assessed in 12 normotensive patients with angina pectoris and an ischemic electrocardiographic response to exercise stress." | 3.67 | Systemic and coronary hemodynamic effects of combined alpha- and beta-adrenergic blockade (labetalol) in normotensive patients with stable angina pectoris and positive exercise stress test responses. ( Feldman, RL; Hill, JA; Prida, XE, 1987) |
| "The systemic and coronary hemodynamic effects of combined alpha- and beta-adrenergic blockade produced by oral labetalol were assessed in 12 normotensive patients with angina pectoris and an ischemic electrocardiographic response to exercise stress." | 3.67 | Systemic and coronary hemodynamic effects of combined oral alpha- and beta-adrenergic blockade (labetalol) in normotensive patients with stable angina pectoris and positive exercise stress tests. ( Feldman, RL; Hill, JA; Prida, XE, 1988) |
| "1 In nine hypertensive subjects with angina pectoris, labetalol diminished the incidence of chest pain occurring spontaneously or induced by exercise." | 3.66 | Open evaluation of labetalol in the treatment of angina pectoris occurring in hypertensive patients. ( Besterman, EM; Spencer, M, 1979) |
| "Labetalol and atenolol were equivalent in control of blood pressure at rest, exercise tolerance and use of nitroglycerin; however, heart rates at rest and during exercise were higher with labetalol (p less than 0." | 2.66 | Double-blind trial comparing labetalol with atenolol in the treatment of systemic hypertension with angina pectoris. ( Jee, LD; Opie, LH, 1985) |
| "Thus labetalol would appear to be an effective antianginal agent." | 2.37 | Labetalol in normotensive patients with angina pectoris. ( Fox, K; Quyyumi, AA, 1988) |
| " The dosage and choice of drugs are based on pharmaco-kinetic and dynamic data in animals and man." | 2.36 | Clinical pharmacology of beta-adrenoceptor antagonism in angina pectoris: an overview. ( Oh, VM, 1980) |
| "Atenolol and nadolol have been ascertained to be effective long acting antianginal drugs." | 1.27 | [Comparative study of the action of a series of new beta-adrenergic receptor blockaders in patients with effort angina]. ( Desiatnichenko, VM; Romakov, AIu; Sagirov, AM; Sobol', IuS; Sumarokov, AB, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (88.24) | 18.7374 |
| 1990's | 2 (5.88) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (5.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stankowski, RV | 1 |
| Kloner, RA | 1 |
| Rezkalla, SH | 1 |
| Richards, JR | 1 |
| Lange, RA | 2 |
| Oh, VM | 1 |
| Frishman, WH | 2 |
| Strom, JA | 1 |
| Kirschner, M | 2 |
| Poland, M | 1 |
| Klein, N | 1 |
| Halprin, S | 2 |
| LeJemtel, TH | 1 |
| Kram, M | 1 |
| Sonnenblick, EH | 1 |
| Romakov, AIu | 1 |
| Sagirov, AM | 1 |
| Desiatnichenko, VM | 1 |
| Sobol', IuS | 1 |
| Sumarokov, AB | 1 |
| Johns, VJ | 1 |
| Taylor, SH | 1 |
| Mulac, KD | 1 |
| Lubbe, WF | 3 |
| White, DA | 2 |
| Nyberg, G | 1 |
| Bjurö, T | 1 |
| Hagman, M | 1 |
| Smith, U | 1 |
| Opie, LH | 3 |
| White, D | 1 |
| Lee, J | 1 |
| Frishman, W | 1 |
| Strom, J | 1 |
| Boehrer, JD | 1 |
| Moliterno, DJ | 1 |
| Willard, JE | 1 |
| Hillis, LD | 1 |
| Cherchi, A | 1 |
| Fonzo, R | 1 |
| Lai, C | 1 |
| Mercuro, G | 1 |
| Besterman, EM | 1 |
| Spencer, M | 1 |
| Prichard, BN | 1 |
| Richards, DA | 1 |
| Bowles, MJ | 1 |
| Smith, L | 1 |
| Glover, DR | 1 |
| Glasser, SP | 1 |
| Bittar, N | 1 |
| Kinhal, V | 1 |
| Bennett, WT | 1 |
| Koehn, DK | 1 |
| Shapiro, W | 1 |
| Charlap, S | 1 |
| Fitzgerald, JD | 1 |
| Kanto, JH | 1 |
| Prida, XE | 2 |
| Hill, JA | 2 |
| Feldman, RL | 2 |
| Zaĭtseva, VI | 1 |
| Sharaeva, ML | 2 |
| Crake, T | 1 |
| Mulcahy, D | 1 |
| Wright, C | 2 |
| Fox, K | 2 |
| Bory, M | 1 |
| Joly, P | 1 |
| Bonnet, JL | 1 |
| Djiane, P | 1 |
| Serradimigni, A | 1 |
| Quyyumi, AA | 2 |
| Mockus, L | 1 |
| Shackell, M | 1 |
| Sutton, GC | 1 |
| Fox, KM | 1 |
| Upward, JW | 1 |
| Akhras, F | 1 |
| Jackson, G | 1 |
| Jee, LD | 1 |
| Broustet, JP | 1 |
| Cherrier, JF | 1 |
| Pic, A | 1 |
7 reviews available for labetalol and Angor Pectoris
| Article | Year |
|---|---|
Clinical pharmacology of beta-adrenoceptor antagonism in angina pectoris: an overview.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Airway Obstruction; Angina Pectoris; Anti | 1980 |
Beta-blocking drugs for arrhythmias, hypertension, and ischemic heart disease.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Animals; Arrhythmias, Cardiac; Atenolol; Blood Pressur | 1984 |
Alpha- and beta-blockade in angina pectoris.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angina Pectoris; Blood Platelets; Carbohy | 1984 |
The possible role of the ancillary properties of beta adrenoceptor antagonists in the management of angina pectoris.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angina Pectoris; Animals; Anxiety Disorde | 1985 |
Labetalol in the treatment of angina pectoris.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angina Pectoris; Clinical Trials as Topic | 1987 |
Labetalol in normotensive patients with angina pectoris.
Topics: Angina Pectoris; Humans; Labetalol | 1988 |
Role of vasodilation in the antihypertensive and antianginal effects of labetalol: implications for therapy of combined hypertension and angina.
Topics: Angina Pectoris; Antihypertensive Agents; Humans; Hypertension; Labetalol; Vasodilation | 1988 |
11 trials available for labetalol and Angor Pectoris
| Article | Year |
|---|---|
Beneficial effect of labetalol in hypertensive patients with angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Ethanolamines; Female; Heart Rate; Humans; Hypertensio | 1983 |
Relation between ST-depression and chest pain in patients with coronary heart disease receiving no treatment and after beta-blockade and combined alpha-beta-blockade.
Topics: Aged; Angina Pectoris; Blood Pressure; Coronary Disease; Electrocardiography; Ethanolamines; Exercis | 1981 |
Labetalol in hypertensive patients with angina pectoris: beneficial effect of combined alpha- and beta-adrenoreceptor blockade.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Clinical Tr | 1978 |
Randomised, double-blind, three-way cross-over study of dilevalol 200 and 400 mg and atenolol 100 mg once-daily in patients with chronic stable angina pectoris.
Topics: Administration, Oral; Adult; Aged; Analysis of Variance; Angina Pectoris; Atenolol; Blood Pressure; | 1990 |
The efficacy and safety of dilevalol in patients with chronic stable angina pectoris.
Topics: Adrenergic beta-Antagonists; Adult; Angina Pectoris; Chronic Disease; Coronary Disease; Double-Blind | 1989 |
Labetalol compared with propranolol in patients with both angina pectoris and systemic hypertension: a double-blind study.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Exercis | 1989 |
Labetalol in the treatment of angina pectoris.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angina Pectoris; Clinical Trials as Topic | 1987 |
Labetalol in the treatment of stable exertional angina pectoris: a comparison with nifedipine.
Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Double-Blind Method; Exercise Test; Female; | 1988 |
Effects of combined alpha and beta adrenoceptor blockade in patients with angina pectoris. A double blind study comparing labetalol with placebo.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Electro | 1985 |
Oral labetalol in the management of stable angina pectoris in normotensive patients.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, | 1985 |
Double-blind trial comparing labetalol with atenolol in the treatment of systemic hypertension with angina pectoris.
Topics: Adult; Angina Pectoris; Atenolol; Clinical Trials as Topic; Double-Blind Method; Ethanolamines; Fema | 1985 |
17 other studies available for labetalol and Angor Pectoris
| Article | Year |
|---|---|
Letter to the editor response.
Topics: Angina Pectoris; Cocaine; Female; Humans; Labetalol; Male | 2016 |
Labetalol and cardiovascular consequences of cocaine use.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Cardiovascular Diseases; Cocaine; Cocaine-Related Diso | 2016 |
Labetalol therapy in patients with systemic hypertension and angina pectoris: effects of combined alpha and beta adrenoceptor blockade.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Angina Pectoris; Echocardiography; | 1981 |
[Comparative study of the action of a series of new beta-adrenergic receptor blockaders in patients with effort angina].
Topics: Adrenergic beta-Antagonists; Adult; Angina Pectoris; Atenolol; Echocardiography; Exercise Test; Hemo | 1983 |
The value of combined alpha- and beta-adrenoceptor blockade in angina pectoris.
Topics: Angina Pectoris; Ethanolamines; Hemodynamics; Humans; Labetalol | 1983 |
Alternatives to beta-blockade in therapy of hypertension with angina pectoris: role of nifedipine or of labetalol.
Topics: Angina Pectoris; Blood Pressure; Drug Therapy, Combination; Ethanolamines; Exercise Test; Hemodynami | 1982 |
Clinical pharmacology of the new beta-adrenergic blocking drugs. Part II. Effects of oral labetalol in patients with both angina pectoris and hypertension: a preliminary experience.
Topics: Administration, Oral; Angina Pectoris; Blood Pressure; Ethanolamines; Exercise Test; Heart Rate; Hum | 1980 |
Influence of labetalol on cocaine-induced coronary vasoconstriction in humans.
Topics: Adult; Aged; Analysis of Variance; Angina Pectoris; Cocaine; Female; Humans; Labetalol; Male; Middle | 1993 |
[Influence of labetalol on the exercise tolerance test in patients with angina pectoris].
Topics: Adult; Angina Pectoris; Blood Pressure; Double-Blind Method; Ethanolamines; Exercise Test; Heart Rat | 1978 |
Open evaluation of labetalol in the treatment of angina pectoris occurring in hypertensive patients.
Topics: Angina Pectoris; Blood Pressure; Electrocardiography; Ethanolamines; Eye Manifestations; Female; Hea | 1979 |
Labetalol, an alpha- and beta-adrenoceptor-blocking agent: its use in therapeutics. A summary of the symposium.
Topics: Administration, Oral; Anesthesia; Angina Pectoris; Catecholamines; Ethanolamines; Female; Hemodynami | 1979 |
Systemic and coronary hemodynamic effects of combined alpha- and beta-adrenergic blockade (labetalol) in normotensive patients with stable angina pectoris and positive exercise stress test responses.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angina Pectoris; Coronary Circulation; El | 1987 |
[Comparative characteristics of the hemodynamic and antianginal actions of obzidan and albetol in patients with stenocardia].
Topics: Adrenergic beta-Antagonists; Adult; Angina Pectoris; Drug Evaluation; Exercise Test; Hemodynamics; H | 1988 |
[Ergometrine test in 1200 consecutive patients presenting with normal coronary vessels].
Topics: Adult; Aged; Angina Pectoris; Autonomic Nerve Block; Coronary Angiography; Coronary Vasospasm; Elect | 1987 |
Systemic and coronary hemodynamic effects of combined oral alpha- and beta-adrenergic blockade (labetalol) in normotensive patients with stable angina pectoris and positive exercise stress tests.
Topics: Administration, Oral; Adult; Aged; Angina Pectoris; Blood Pressure; Coronary Circulation; Coronary D | 1988 |
[Anti-angina and hemodynamic action of labetalol in angina patients].
Topics: Adult; Angina Pectoris; Hemodynamics; Humans; Labetalol; Male; Middle Aged | 1987 |
[Trial of labetalol in effort angina pectoris].
Topics: Angina Pectoris; Blood Pressure; Electrocardiography; Ethanolamines; Exercise Test; Heart Rate; Huma | 1985 |