labetalol has been researched along with Anesthesia in 31 studies
Labetalol: A salicylamide derivative that is a non-cardioselective blocker of BETA-ADRENERGIC RECEPTORS and ALPHA-1 ADRENERGIC RECEPTORS.
labetalol : A diastereoisomeric mixture of approximately equal amounts of all four possible stereoisomers ((R,S)-labetolol, (S,R)-labetolol, (S,S)-labetalol and (R,R)-labetalol). It is an adrenergic antagonist used to treat high blood pressure.
2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide : A member of the class of benzamides that is benzamide substituted by a hydroxy group at position 2 and by a 1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl group at position 5.
Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The findings of this study suggest that deliberate hypotensive anesthesia with labetalol and isoflurane may be of benefit in scoliosis surgery by reducing blood loss, the need of blood replacement and operating time." | 7.69 | Deliberate hypotensive anesthesia with labetalol in reconstructive surgery for scoliosis. ( Chen, WC; Chung, PC; Sum, DC, 1996) |
| "Labetalol, an alpha and beta adrenergic blocking drug, was used during anesthesia for removal of a very large pheochromocytoma which was predominantly epinephrine secreting." | 7.66 | Use of labetalol during anesthesia for pheochromocytoma removal. ( de Rood, M; Lambilliotte, JP; Levarlet, M; Lignian, H; Van Stratum, M, 1983) |
| "Labetalol was used as antihypertensive agent and was given in repeated bolus (up to total dose of 2 mg/kg) intravenously before skin incision and no supplemental dosage was given later on." | 5.29 | Preliminary experience of using fixed dose of intravenous labetalol in surgical resection of pheochromocytoma. ( Chung, PC; Sum, DC, 1993) |
| " It has also been used intravenously in phaeochromocytoma, tetanus, clonidine withdrawal, and as an adjunct to halothane to produce hypotensive anaesthesia." | 4.76 | Combined alpha- and beta-receptor inhibition in the treatment of hypertension. ( Prichard, BN, 1984) |
| "Labetalol, an alpha and beta adrenergic blocking drug, was used during anesthesia for removal of a very large pheochromocytoma which was predominantly epinephrine secreting." | 3.66 | Use of labetalol during anesthesia for pheochromocytoma removal. ( de Rood, M; Lambilliotte, JP; Levarlet, M; Lignian, H; Van Stratum, M, 1983) |
| "Labetalol is a unique antihypertensive agent which is a competitive peripheral antagonist at both alpha- and beta-adrenoceptor sites." | 2.37 | Current status of labetalol, the first alpha- and beta-blocking agent. ( Kanto, JH, 1985) |
| "Labetalol was used as antihypertensive agent and was given in repeated bolus (up to total dose of 2 mg/kg) intravenously before skin incision and no supplemental dosage was given later on." | 1.29 | Preliminary experience of using fixed dose of intravenous labetalol in surgical resection of pheochromocytoma. ( Chung, PC; Sum, DC, 1993) |
| "Labetalol is a mixture of four isomers." | 1.26 | Alpha and beta adrenoceptor blocking properties of labetalol and its R,R-isomer, SCH 19927. ( Baum, T; Glennon, J; Gold, EH; Pula, KK; Sabin, CS; Sybertz, EJ; Vliet, GV, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (77.42) | 18.7374 |
| 1990's | 7 (22.58) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sybertz, EJ | 1 |
| Sabin, CS | 1 |
| Pula, KK | 1 |
| Vliet, GV | 1 |
| Glennon, J | 1 |
| Gold, EH | 1 |
| Baum, T | 1 |
| Brittain, RT | 1 |
| Drew, GM | 1 |
| Levy, GP | 2 |
| Prichard, BN | 2 |
| van Hasselt, G | 1 |
| MacKenzie, I | 1 |
| Edwards, JC | 1 |
| Nakai, T | 1 |
| Sakio, H | 1 |
| Isobe, K | 1 |
| Iwatsuki, K | 1 |
| Yamada, R | 1 |
| Okuda, C | 1 |
| Van Stratum, M | 1 |
| Levarlet, M | 1 |
| Lambilliotte, JP | 1 |
| Lignian, H | 1 |
| de Rood, M | 1 |
| Forbes, R | 1 |
| Clanachan, AS | 1 |
| Moonie, GT | 1 |
| Van Aken, H | 1 |
| Puchstein, C | 1 |
| Hidding, J | 1 |
| Pasch, T | 1 |
| Pingel, I | 1 |
| Scott, DB | 1 |
| Robertson, JI | 1 |
| Kanto, J | 1 |
| Pakkanen, A | 1 |
| Allonen, H | 1 |
| Kleimola, T | 1 |
| Mäntylä, R | 1 |
| Dage, RC | 1 |
| Hsieh, CP | 1 |
| Chung, PC | 2 |
| Sum, DC | 2 |
| Chen, WC | 1 |
| Huang, YC | 1 |
| Wu, BN | 1 |
| Lin, YT | 1 |
| Chen, SJ | 1 |
| Chiu, CC | 1 |
| Cheng, CJ | 1 |
| Chen, IJ | 1 |
| Kennedy, I | 1 |
| Cope, DH | 1 |
| Kaufman, L | 1 |
| Richards, DA | 1 |
| Noguchi, K | 1 |
| Kato, T | 1 |
| Kinjo, N | 1 |
| Moromizato, H | 1 |
| Sakanashi, M | 1 |
| Ruffolo, RR | 2 |
| Sauermelch, CF | 2 |
| Willette, RN | 2 |
| den Boer, MO | 1 |
| Sassen, LM | 1 |
| van der Giessen, WJ | 1 |
| Saxena, PR | 1 |
| Verdouw, PD | 1 |
| Lee, SC | 1 |
| Fung, ST | 1 |
| Lee, JH | 1 |
| Miranda, AF | 1 |
| Kanto, JH | 1 |
| Stone, JG | 1 |
| Foëx, P | 1 |
| Sear, JW | 1 |
| Johnson, LL | 1 |
| Khambatta, HJ | 1 |
| Triner, L | 1 |
| Shapira, Y | 1 |
| Gertel, M | 1 |
| Saarnivaara, L | 1 |
| Klemola, UM | 1 |
| Lindgren, L | 1 |
| Casthely, PA | 1 |
| Villanueva, R | 1 |
| Rabinowitz, L | 1 |
| Gandhi, P | 1 |
| Litwak, B | 1 |
| Fyman, PN | 1 |
3 reviews available for labetalol and Anesthesia
| Article | Year |
|---|---|
Combined alpha- and beta-receptor inhibition in the treatment of hypertension.
Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia; Antihyp | 1984 |
Current status of labetalol, the first alpha- and beta-blocking agent.
Topics: Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia; Biot | 1985 |
[New drugs for deliberate hypotension in anesthesia].
Topics: Anesthesia; Animals; Humans; Hydralazine; Hypotension, Controlled; Isoflurane; Labetalol | 1988 |
2 trials available for labetalol and Anesthesia
| Article | Year |
|---|---|
[Effects of labetalol and nitroglycerin during induction of anesthesia and endotracheal intubation in hypertensive patients].
Topics: Adult; Aged; Anesthesia; Blood Pressure; Female; Humans; Hypertension; Intubation, Intratracheal; La | 1989 |
Myocardial ischemia in untreated hypertensive patients: effect of a single small oral dose of a beta-adrenergic blocking agent.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Aged; Anesthesia; Atenolol; Clinical Trials as To | 1988 |
26 other studies available for labetalol and Anesthesia
| Article | Year |
|---|---|
Alpha and beta adrenoceptor blocking properties of labetalol and its R,R-isomer, SCH 19927.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia; Animals; Autonomic Fibers, Pr | 1981 |
The alpha- and beta-adrenoceptor blocking potencies of labetalol and its individual stereoisomers in anaesthetized dogs and in isolated tissues.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia; Animals; Aorta, Thoracic; Dog | 1982 |
Use of vecuronium and labetalol in patients with phaeochromocytoma.
Topics: Adrenal Gland Neoplasms; Adult; Anesthesia; Humans; Hypertension; Jaw Fractures; Labetalol; Male; Pa | 1984 |
[Effects of labetalol and phentolamine on plasma catecholamine concentrations in anesthetized dogs].
Topics: Anesthesia; Animals; Blood Pressure; Catecholamines; Dogs; Ethanolamines; Heart Rate; Labetalol; Phe | 1983 |
Use of labetalol during anesthesia for pheochromocytoma removal.
Topics: Adrenal Gland Neoplasms; Aged; Anesthesia; Epinephrine; Ethanolamines; Female; Humans; Hypertension; | 1983 |
Adrenaline induced dysrhythmias: comparison of the antidysrhythmic effect of labetalol with propranolol during normocarbia and hypercarbia in halothane anaesthetized cats.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Carbon Dioxide; Cats; Epinephrine | 1980 |
The use of labetalol in producing deliberate hypotension and its effects on intracranial pressure in dogs.
Topics: Anesthesia; Animals; Cardiac Output; Dogs; Ethanolamines; Female; Hemodynamics; Hypotension, Control | 1982 |
[Deliberate hypotension during rhinosurgery using labetalol, a combined alpha- and beta-adrenoceptor antagonist (author's transl)].
Topics: Adult; Anesthesia; Blood Pressure; Enflurane; Ethanolamines; Female; Heart Rate; Humans; Hypotension | 1982 |
The use of labetalol in anaesthesia.
Topics: Anesthesia; Blood Pressure; Ethanolamines; Halothane; Heart Rate; Humans; Hypertension; Hypotension, | 1982 |
Labetalol: the nineteen-eighties.
Topics: Adrenal Gland Neoplasms; Anesthesia; Coronary Disease; Ethanolamines; Female; Humans; Hypertension; | 1982 |
The use of labetalol as a moderate hypotensive agent in otological operations--plasma concentrations after intravenous administration.
Topics: Adult; Anesthesia; Blood Pressure; Double-Blind Method; Ear; Ethanolamines; Female; Half-Life; Human | 1980 |
Direct vasodilatation by labetalol in anaesthetized dogs.
Topics: Adrenalectomy; Anesthesia; Animals; Clonidine; Diazoxide; Dogs; Ethanolamines; Female; Hemodynamics; | 1980 |
Preliminary experience of using fixed dose of intravenous labetalol in surgical resection of pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Adult; Aged; Anesthesia; Blood Pressure; Heart Rate; Humans; Injections, In | 1993 |
Deliberate hypotensive anesthesia with labetalol in reconstructive surgery for scoliosis.
Topics: Adolescent; Adult; Anesthesia; Antihypertensive Agents; Humans; Hypotension, Controlled; Labetalol; | 1996 |
Eugenodilol: a third-generation beta-adrenoceptor blocker, derived from eugenol, with alpha-adrenoceptor blocking and beta2-adrenoceptor agonist-associated vasorelaxant activities.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anesthesia; Animals; Aorta, Thoracic; Bradyca | 1999 |
Combined alpha- and beta-adrenoceptor blocking drug AH 5158: further studies on alpha-adrenoceptor blockade in anaesthetized animals.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia; Animals; Blood Pressure; Cats | 1975 |
Use of labetalol during halothane anaesthesia.
Topics: Adolescent; Adult; Aged; Anesthesia; Blood Pressure; Child; Ethanolamines; Halothane; Humans; Hypote | 1979 |
Use of labetalol during hypotensive anaesthesia and in the management of phaeochromocytoma.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Anesthesia; Ethanolamines; Female; Heart Rate; Humans; H | 1979 |
Labetalol, an alpha- and beta-adrenoceptor-blocking agent: its use in therapeutics. A summary of the symposium.
Topics: Administration, Oral; Anesthesia; Angina Pectoris; Catecholamines; Ethanolamines; Female; Hemodynami | 1979 |
Comparative effects of arotinolol, labetalol and propranolol on regional myocardial dysfunction induced by flow-limiting coronary stenosis in anesthetized dogs.
Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Blood Pressure; Cardiomyopathies; Coronary Vessels | 1990 |
Hemodynamic differences between carvedilol and labetalol in the cutaneous circulation.
Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Blood Pressure; Carbazoles; Carvedilol; Heart Rate | 1990 |
Effects of dilevalol in the anesthetized pig with a partially occluded coronary artery.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia; Animals; Chloralose; Coronary | 1990 |
Local cutaneous hemodynamic effects of carvedilol and labetalol in the anesthetized rat.
Topics: Anesthesia; Animals; Blood Pressure; Carbazoles; Carvedilol; Heart Rate; Labetalol; Male; Microcircu | 1990 |
Experience with hypotensive anaesthesia in a peripheral general hospital.
Topics: Adolescent; Adult; Anesthesia; Child; Female; Halothane; Hospitals, General; Humans; Hypotension; La | 1989 |
Labetalol as a hypotensive agent for middle ear microsurgery.
Topics: Acid-Base Equilibrium; Adult; Anesthesia; Blood Pressure; Ear, Middle; Female; Hemostasis; Humans; H | 1987 |
Intrapulmonary shunting during deliberate hypotension with nifedipine, diltiazem and labetalol in dogs.
Topics: Anesthesia; Animals; Benzazepines; Blood Pressure; Diltiazem; Dogs; Ethanolamines; Heart Rate; Hypot | 1985 |