labdane and Ovarian-Neoplasms

labdane has been researched along with Ovarian-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for labdane and Ovarian-Neoplasms

Article	Year
Five new labdane diterpenes from Aster oharai. Journal of natural products, 2002, Volume: 65, Issue:8 Five new labdane diterpenes (1-5) together with seven known diterpenes have been isolated from a methanol extract of the aerial parts of Aster oharai. Five new structures were determined as 7alpha-hydroperoxylabda-8(17),14-dien-13(R)-ol-4-O-acetyl-alpha-L-6-deoxyidopyranoside (1), 7alpha-hydroperoxylabda-8,14-dien-13(R)-ol-4-O-acetyl-alpha-L-6-deoxyidopyranoside (2), labda-7,14-dien-13(R)-ol-4-O-acetyl-alpha-L-rhamnopyranoside (3), labda-7,14-dien-13(R)-ol-3-O-acetyl-alpha-L-rhamnopyranoside (4), and labda-7,14-dien-13(R)-ol-2-O-acetyl-alpha-L-rhamnopyranoside (5), on the basis of spectroscopic methods. Compound 1 showed moderate cytotoxicity against four cultured human tumor cell lines with ED(50) values ranging from 1.1 to 7.7 microg/mL. Topics: Asteraceae; beta-Glucosidase; Chromatography, Thin Layer; Colorectal Neoplasms; Diterpenes; Electron Spin Resonance Spectroscopy; Female; Humans; Hydrolysis; Korea; Lung Neoplasms; Molecular Conformation; Molecular Structure; Nervous System Neoplasms; Nuclear Magnetic Resonance, Biomolecular; Ovarian Neoplasms; Plants, Medicinal; Skin Neoplasms; Stereoisomerism; Tumor Cells, Cultured	2002

Article

Year

Five new labdane diterpenes from Aster oharai.

Journal of natural products, 2002, Volume: 65, Issue:8

Five new labdane diterpenes (1-5) together with seven known diterpenes have been isolated from a methanol extract of the aerial parts of Aster oharai. Five new structures were determined as 7alpha-hydroperoxylabda-8(17),14-dien-13(R)-ol-4-O-acetyl-alpha-L-6-deoxyidopyranoside (1), 7alpha-hydroperoxylabda-8,14-dien-13(R)-ol-4-O-acetyl-alpha-L-6-deoxyidopyranoside (2), labda-7,14-dien-13(R)-ol-4-O-acetyl-alpha-L-rhamnopyranoside (3), labda-7,14-dien-13(R)-ol-3-O-acetyl-alpha-L-rhamnopyranoside (4), and labda-7,14-dien-13(R)-ol-2-O-acetyl-alpha-L-rhamnopyranoside (5), on the basis of spectroscopic methods. Compound 1 showed moderate cytotoxicity against four cultured human tumor cell lines with ED(50) values ranging from 1.1 to 7.7 microg/mL.

Topics: Asteraceae; beta-Glucosidase; Chromatography, Thin Layer; Colorectal Neoplasms; Diterpenes; Electron Spin Resonance Spectroscopy; Female; Humans; Hydrolysis; Korea; Lung Neoplasms; Molecular Conformation; Molecular Structure; Nervous System Neoplasms; Nuclear Magnetic Resonance, Biomolecular; Ovarian Neoplasms; Plants, Medicinal; Skin Neoplasms; Stereoisomerism; Tumor Cells, Cultured

2002