Page last updated: 2024-09-05

l 778,123 and Benign Neoplasms

l 778,123 has been researched along with Benign Neoplasms in 6 studies

Research

Studies (6)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	6 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Adjei, AA; Dy, GK; Haluska, P	1
Helbig, G; Hołowiecki, J	1
Abbruzzese, A; Budillon, A; Caponigro, F; Caraglia, M; Marra, M; Tagliaferri, P	1
Bernhard, E; Hahn, SM; Jones, HA; McKenna, WG	1
Britten, CD; Deutsch, P; Lee, Y; Lobell, RB; Mazina, KE; McCreery, H; Patnaik, A; Pezzuli, S; Rowinsky, EK; Soignet, S; Spriggs, D; Yao, SL	1
Bell, IM	1

Reviews

5 review(s) available for l 778,123 and Benign Neoplasms

Article	Year
Farnesyl transferase inhibitors as anticancer agents. European journal of cancer (Oxford, England : 1990), 2002, Volume: 38, Issue:13 Topics: Alkyl and Aryl Transferases; Antineoplastic Agents; Benzodiazepines; Cell Division; Clinical Trials as Topic; Combined Modality Therapy; Enzyme Inhibitors; Farnesyltranstransferase; Genes, ras; Humans; Imidazoles; Neoplasms; Piperidines; Pyridines; Quinolones; Tumor Cells, Cultured	2002
[Ras signaling pathway as a target for farnesyltransferase inhibitors--a new, promising prospects in the treatment for malignant disorders]. Wiadomosci lekarskie (Warsaw, Poland : 1960), 2004, Volume: 57, Issue:9-10 Topics: Alkyl and Aryl Transferases; Antineoplastic Agents; Farnesyltranstransferase; Genes, ras; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Imidazoles; Neoplasms; Piperidines; Point Mutation; Pyridines; Quinolones; Signal Transduction	2004
Isoprenylation of intracellular proteins as a new target for the therapy of human neoplasms: preclinical and clinical implications. Current drug targets, 2005, Volume: 6, Issue:3 Topics: Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Benzodiazepines; Farnesyltranstransferase; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Mevalonic Acid; Neoplasms; Phosphatidylinositol 3-Kinases; Piperidines; Protein Prenylation; Protein Processing, Post-Translational; Pyridines; Quinolones; ras Proteins	2005
Ras inhibitors and radiation therapy. Seminars in radiation oncology, 2001, Volume: 11, Issue:4 Topics: Alkyl and Aryl Transferases; Enzyme Inhibitors; Humans; Imidazoles; Neoplasm Recurrence, Local; Neoplasms; Proto-Oncogene Proteins p21(ras); Radiation Tolerance; ras Proteins; Signal Transduction	2001
Inhibitors of farnesyltransferase: a rational approach to cancer chemotherapy? Journal of medicinal chemistry, 2004, Apr-08, Volume: 47, Issue:8 Topics: Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Drug Design; Farnesyltranstransferase; Genes, ras; Humans; Neoplasms	2004

Trials

1 trial(s) available for l 778,123 and Benign Neoplasms

Article	Year
A phase I and pharmacological study of the farnesyl protein transferase inhibitor L-778,123 in patients with solid malignancies. Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:12 Topics: Adult; Alkyl and Aryl Transferases; Area Under Curve; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Imidazoles; Male; Metabolic Clearance Rate; Neoplasms; Neutropenia; Thrombocytopenia	2001

Article

Year

A phase I and pharmacological study of the farnesyl protein transferase inhibitor L-778,123 in patients with solid malignancies.

Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:12

Topics: Adult; Alkyl and Aryl Transferases; Area Under Curve; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Imidazoles; Male; Metabolic Clearance Rate; Neoplasms; Neutropenia; Thrombocytopenia

2001