l 739749 has been researched along with Cell Transformation, Neoplastic in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davide, JP; deSolms, SJ; Gibbs, JB; Giuliani, EA; Graham, SL; Kohl, NE; Oliff, A; Prendergast, GC | 1 |
| Davide, JP; Lebowitz, PF; Prendergast, GC | 1 |
| Brown, MS; Goldstein, JL; James, G | 1 |
| Davide, JP; Kohl, NE; Lebowitz, PF; Prendergast, GC; Wechsler-Reya, R | 1 |
4 other study(ies) available for l 739749 and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Farnesyltransferase inhibition causes morphological reversion of ras-transformed cells by a complex mechanism that involves regulation of the actin cytoskeleton.
Topics: Actins; Alkyl and Aryl Transferases; Animals; Blotting, Western; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cytoskeleton; Electrophoresis, Polyacrylamide Gel; Farnesyltranstransferase; Genes, ras; Kinetics; Oligopeptides; Oncogene Proteins v-raf; Oncogenes; Protein-Tyrosine Kinases; Rats; Retroviridae Proteins, Oncogenic; Transferases | 1994 |
Evidence that farnesyltransferase inhibitors suppress Ras transformation by interfering with Rho activity.
Topics: Alkyl and Aryl Transferases; Animals; Base Sequence; Cell Transformation, Neoplastic; Chlorocebus aethiops; DNA Primers; Enzyme Inhibitors; Farnesyltranstransferase; Genes, ras; GTP-Binding Proteins; Humans; Membrane Proteins; Molecular Sequence Data; Myristic Acid; Myristic Acids; Oligopeptides; Polymerase Chain Reaction; Protein Processing, Post-Translational; Rats; Recombinant Proteins; rhoA GTP-Binding Protein; rhoB GTP-Binding Protein; Transfection; Transferases | 1995 |
Resistance of K-RasBV12 proteins to farnesyltransferase inhibitors in Rat1 cells.
Topics: Alkyl and Aryl Transferases; Animals; Benzodiazepines; Cell Line; Cell Transformation, Neoplastic; Enzyme Inhibitors; Farnesyltranstransferase; Mevalonic Acid; Oligopeptides; Protein Prenylation; ras Proteins; Rats; Recombinant Fusion Proteins; Transfection; Transferases | 1996 |
Resistance of a variant ras-transformed cell line to phenotypic reversion by farnesyl transferase inhibitors.
Topics: Actins; Alkyl and Aryl Transferases; Animals; Cell Transformation, Neoplastic; Cytoskeleton; Drug Resistance; Enzyme Inhibitors; Farnesyltranstransferase; Genes, ras; GTP-Binding Proteins; Membrane Proteins; Myristates; Oligopeptides; Phenotype; Protein Processing, Post-Translational; Rats; rhoB GTP-Binding Protein; Transferases; Tumor Cells, Cultured | 1996 |