l-706000 and Obesity

l-706000 has been researched along with Obesity* in 1 studies

Other Studies

1 other study(ies) available for l-706000 and Obesity

Article	Year
Discovery of a piperazine urea based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist. Bioorganic & medicinal chemistry letters, 2011, Apr-15, Volume: 21, Issue:8 We report the discovery of piperazine urea based compound 1, a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist. Compound 1 shows anti-obesity efficacy without potentiating erectile activity in the rodent models. Topics: Administration, Oral; Animals; Biological Availability; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Eating; Haplorhini; Mice; Obesity; Piperazines; Rats; Rats, Sprague-Dawley; Receptor, Melanocortin, Type 4; Structure-Activity Relationship; Urea	2011

Article

Year

Discovery of a piperazine urea based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist.

Bioorganic & medicinal chemistry letters, 2011, Apr-15, Volume: 21, Issue:8

We report the discovery of piperazine urea based compound 1, a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist. Compound 1 shows anti-obesity efficacy without potentiating erectile activity in the rodent models.

Topics: Administration, Oral; Animals; Biological Availability; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Eating; Haplorhini; Mice; Obesity; Piperazines; Rats; Rats, Sprague-Dawley; Receptor, Melanocortin, Type 4; Structure-Activity Relationship; Urea

2011