l-683590 and Asthma

l-683590 has been researched along with Asthma* in 1 studies

Other Studies

1 other study(ies) available for l-683590 and Asthma

Article	Year
Preparation and immunosuppressive activity of 32-(O)-acylated and 32-(O)-thioacylated analogues of ascomycin. Bioorganic & medicinal chemistry letters, 1999, Jan-18, Volume: 9, Issue:2 A series of 32-(O)-acylated and 32-(O)-thioacylated derivatives of the antibiotic ascomycin (1) have been synthesized. These readily accessible analogues exhibit potent immunosuppressive activity in vitro, as measured by an interleukin-2 reporter gene assay and the mixed lymphocyte reaction. Such molecules are expected to have a therapeutic potential in chronic inflammatory diseases of the airways such as asthma. Topics: Acylation; Anti-Bacterial Agents; Asthma; Immunosuppressive Agents; Inhibitory Concentration 50; Tacrolimus	1999

Article

Year

Preparation and immunosuppressive activity of 32-(O)-acylated and 32-(O)-thioacylated analogues of ascomycin.

Bioorganic & medicinal chemistry letters, 1999, Jan-18, Volume: 9, Issue:2

A series of 32-(O)-acylated and 32-(O)-thioacylated derivatives of the antibiotic ascomycin (1) have been synthesized. These readily accessible analogues exhibit potent immunosuppressive activity in vitro, as measured by an interleukin-2 reporter gene assay and the mixed lymphocyte reaction. Such molecules are expected to have a therapeutic potential in chronic inflammatory diseases of the airways such as asthma.

Topics: Acylation; Anti-Bacterial Agents; Asthma; Immunosuppressive Agents; Inhibitory Concentration 50; Tacrolimus

1999