Compounds > kyotorphin
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kyotorphin and Pain

kyotorphin has been researched along with Pain in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (35.29)18.2507
2000's6 (35.29)29.6817
2010's5 (29.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bammert, CE; Bi, L; Bi, W; Bi, Y; Gao, X; Legalley, TD; Michael Gibson, K; Wang, JX; Xue, P; Yan, X; Zhang, Y1
Bardaji, E; Castanho, MA; Heras, M; Oliveira, M; Ribeiro, MM; Santos, SM; Santos, SS; Sousa, DSC; Tavares, I1
Abu Hammad, I; Bachar, T; Grinberg, S; Heldman, E; Linder, C; Popov, M; Stepensky, D1
Hu, Y; Jiang, H; Keep, RF; Smith, DE1
Bardaji, E; Castanho, M; Correia, A; Heras, M; Martins, I; Pinto, A; Pinto, M; Ribeiro, MM; Tavares, I1
Horváth, G; Mécs, L1
Bocheva, A; Lazarova, M1
Bocheva, A1
Bocheva, AI; Dzambazova-Maximova, EB1
Inoue, M; Nakayamada, H; Tokuyama, S; Ueda, H1
Danilova, EI; Grafova, VN; Kukushkin, ML; Zinkevich, VA1
Inoue, M; Ueda, H; Yamada, T1
Inoue, M; Ueda, H1
Inoue, M; Schiller, PW; Ueda, H; Weltrowska, G1
Hazato, T; Kaya, K; Nishimura, K; Satoh, M; Takagi, H; Ueda, H1
Satoh, M1
Takagi, H1

Reviews

2 review(s) available for kyotorphin and Pain

ArticleYear
Antinociception by endogenous ligands at peripheral level.
    Ideggyogyaszati szemle, 2011, Mar-30, Volume: 64, Issue:5-6

    Topics: Analgesics, Opioid; Animals; Annexin A1; beta-Endorphin; Cytokines; Endorphins; Excitatory Amino Acid Agents; Hemoglobins; Kynurenic Acid; Ligands; Lipid Metabolism; Melatonin; Mice; Neuropeptides; Neurotransmitter Agents; Nociceptin; Oligopeptides; Opioid Peptides; Pain; Pain Measurement; Pain Threshold; Peptide Fragments; Peripheral Nervous System; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Somatostatin

2011
[Physiological and pharmacological actions of a neuroactive dipeptide, kyotorphin, and its precursor, L-arginine, and clinical application].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1990, Volume: 96, Issue:3

    Topics: Analgesics; Animals; Arginine; Brain; Chronic Disease; Endorphins; Humans; Pain

1990

Other Studies

15 other study(ies) available for kyotorphin and Pain

ArticleYear
Anti-inflammatory, analgesic and antioxidant activities of novel kyotorphin-nitroxide hybrid molecules.
    Bioorganic & medicinal chemistry letters, 2016, Apr-15, Volume: 26, Issue:8

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Dose-Response Relationship, Drug; Edema; Endorphins; Mice; Mitochondria; Molecular Structure; Nitrogen Oxides; Pain; Pain Measurement; Structure-Activity Relationship; Xylenes

2016
Side-effects of analgesic kyotorphin derivatives: advantages over clinical opioid drugs.
    Amino acids, 2013, Volume: 45, Issue:1

    Topics: Analgesics, Opioid; Animals; Blood Pressure; Constipation; Endorphins; Ibuprofen; Locomotion; Male; Morphine; Pain; Rats; Rats, Wistar; Tramadol

2013
Delivery of analgesic peptides to the brain by nano-sized bolaamphiphilic vesicles made of monolayer membranes.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2013, Volume: 85, Issue:3 Pt A

    Topics: Analgesics; Animals; Blood-Brain Barrier; Brain; Cations; Chitosan; Cholinesterases; Delayed-Action Preparations; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Endorphins; Enkephalin, Leucine; Furans; Male; Mice; Mice, Inbred ICR; Nanoparticles; Pain; Peptides; Pyridones; Tissue Distribution

2013
Enhanced antinociceptive response to intracerebroventricular kyotorphin in Pept2 null mice.
    Journal of neurochemistry, 2009, Volume: 109, Issue:5

    Topics: Analgesics; Animals; Biological Transport; Carbon Isotopes; Dose-Response Relationship, Drug; Endorphins; Female; Hot Temperature; Injections, Intraventricular; Male; Mannitol; Mice; Mice, Knockout; Pain; Pain Measurement; Reaction Time; Symporters; Tritium

2009
Inhibition of nociceptive responses after systemic administration of amidated kyotorphin.
    British journal of pharmacology, 2011, Volume: 163, Issue:5

    Topics: Acute Disease; Administration, Oral; Analgesics; Animals; Blood-Brain Barrier; Chronic Disease; Dipeptides; Disease Models, Animal; Endorphins; Injections, Intraperitoneal; Injections, Spinal; Male; Pain; Protein Binding; Rats; Rats, Wistar; Receptors, Opioid

2011
Involvement of nitric oxide in the nociception of kyotorphin, TYR-CAV and MIF-s analogues in the rat spinal cord.
    Methods and findings in experimental and clinical pharmacology, 2003, Volume: 25, Issue:2

    Topics: Acute Disease; Analgesics; Animals; Drug Interactions; Drug Synergism; Endorphins; Injections, Spinal; Male; MSH Release-Inhibiting Hormone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pain; Pain Threshold; Rats; Rats, Wistar; Spinal Cord; Time Factors

2003
Effect of D-arginine on antinociception induced by kyotorphin, Tyr-cav, L-cav and Tyr(Cl2)-cav in rats.
    Methods and findings in experimental and clinical pharmacology, 2004, Volume: 26, Issue:5

    Topics: Analgesics; Animals; Arginine; Canavanine; Endorphins; Male; Pain; Pain Measurement; Rats; Rats, Wistar; Stereoisomerism

2004
Effects of kyotorphin and analogues on nociception and pentylenetetrazole seizures.
    Folia medica, 2004, Volume: 46, Issue:1

    Topics: Analgesics; Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Endorphins; Male; Pain; Pain Measurement; Pentylenetetrazole; Rats; Rats, Wistar; Seizures

2004
Peripheral non-opioid analgesic effects of kyotorphin in mice.
    Neuroscience letters, 1997, Oct-24, Volume: 236, Issue:1

    Topics: Afferent Pathways; Analgesics; Animals; Bradykinin Receptor Antagonists; Dose-Response Relationship, Drug; Endorphins; Male; Mice; Pain

1997
[L-Arginine effects during central spinal pain syndrome].
    Biulleten' eksperimental'noi biologii i meditsiny, 1999, Volume: 127, Issue:2

    Topics: Animals; Arginine; Dose-Response Relationship, Drug; Endorphins; GABA Modulators; Nitric Oxide; Pain; Pain Measurement; Penicillin G; Rats; Spinal Cord; Syndrome

1999
Low dose of kyotorphin (tyrosine-arginine) induces nociceptive responses through a substance P release from nociceptor endings.
    Brain research. Molecular brain research, 1999, Jun-08, Volume: 69, Issue:2

    Topics: Animals; Capsaicin; Dose-Response Relationship, Drug; Endorphins; Male; Mice; Mice, Inbred Strains; Nerve Endings; Neurokinin-1 Receptor Antagonists; Pain; Substance P

1999
In vivo signal transduction of nociceptive response by kyotorphin (tyrosine-arginine) through Galpha(i)- and inositol trisphosphate-mediated Ca(2+) influx.
    Molecular pharmacology, 2000, Volume: 57, Issue:1

    Topics: Analgesics; Animals; Calcium; Calcium Channels; Endorphins; GTP-Binding Protein alpha Subunits, Gi-Go; Histamine; Injections, Spinal; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Male; Mice; Neurokinin-1 Receptor Antagonists; Pain; Pain Measurement; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Virulence Factors, Bordetella

2000
An enzymatically stable kyotorphin analog induces pain in subattomol doses.
    Peptides, 2000, Volume: 21, Issue:5

    Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Stability; Endorphins; Male; Mice; Neurokinin-1 Receptor Antagonists; Pain

2000
[Kyotorphin like substance in human cerebrospinal fluid of patients with persistent pain].
    Masui. The Japanese journal of anesthesiology, 1991, Volume: 40, Issue:11

    Topics: Adult; Aged; Analgesics; Chronic Disease; Endorphins; Female; Humans; Male; Middle Aged; Pain

1991
[Neuropeptides and analgesic pharmacology].
    Nihon rinsho. Japanese journal of clinical medicine, 1990, Volume: 48, Issue:5

    Topics: Analgesics; Animals; Delta Sleep-Inducing Peptide; Endorphins; Injections, Intravenous; Injections, Intraventricular; Neprilysin; Neurotransmitter Agents; Pain

1990