Page last updated: 2024-10-18

kynurenine and Weight Gain

kynurenine has been researched along with Weight Gain in 8 studies

Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.

Weight Gain: Increase in BODY WEIGHT over existing weight.

Research Excerpts

ExcerptRelevanceReference
"The hyperglycemia was accompanied with decreased insulin levels, which may have been due to the repression of genes involved in insulin secretion."5.62Kynurenine-Induced Aryl Hydrocarbon Receptor Signaling in Mice Causes Body Mass Gain, Liver Steatosis, and Hyperglycemia. ( Chamberlin, MD; Coker, S; Lewis, LD; Moyer, BJ; Ness, DB; Pooler, DB; Ringelberg, CS; Rojas, IY; Tomlinson, CR; Tosteson, TD; Wilkins, OM, 2021)
" We propose urinary levels of 3-hydroxykynurenine/3-hydroxyanthranilic acid to be surrogate indicators for predicting the adverse effects of D-tryptophan from the break point of body-weight gains and urinary levels of D-tryptophan metabolites."3.80The urinary ratio of 3-hydroxykynurenine/3-hydroxyanthranilic acid is an index to predicting the adverse effects of D-tryptophan in rats. ( Fukuwatari, T; Ohno, T; Sano, M; Shibata, K, 2014)
"The hyperglycemia was accompanied with decreased insulin levels, which may have been due to the repression of genes involved in insulin secretion."1.62Kynurenine-Induced Aryl Hydrocarbon Receptor Signaling in Mice Causes Body Mass Gain, Liver Steatosis, and Hyperglycemia. ( Chamberlin, MD; Coker, S; Lewis, LD; Moyer, BJ; Ness, DB; Pooler, DB; Ringelberg, CS; Rojas, IY; Tomlinson, CR; Tosteson, TD; Wilkins, OM, 2021)
"In this study, the effects of lung inflammation, induced by the intravenous injection of complete Freund's adjuvant, and dietary Trp content on Trp metabolism and availability were investigated."1.35Dietary tryptophan helps to preserve tryptophan homeostasis in pigs suffering from lung inflammation. ( Le Floc'h, N; Melchior, D; Sève, B, 2008)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's1 (12.50)29.6817
2010's3 (37.50)24.3611
2020's3 (37.50)2.80

Authors

AuthorsStudies
Oxenkrug, G1
Summergrad, P1
Rojas, IY1
Moyer, BJ1
Ringelberg, CS1
Wilkins, OM1
Pooler, DB1
Ness, DB1
Coker, S1
Tosteson, TD1
Lewis, LD1
Chamberlin, MD1
Tomlinson, CR1
Lenski, M1
Sidibé, J1
Gholam, M1
Hennart, B1
Dubath, C1
Augsburger, M1
von Gunten, A1
Conus, P1
Allorge, D1
Thomas, A1
Eap, CB1
Gibney, SM1
Fagan, EM1
Waldron, AM1
O'Byrne, J1
Connor, TJ1
Harkin, A1
Shibata, K1
Ohno, T1
Sano, M1
Fukuwatari, T1
da Silva Dias, IC1
Carabelli, B1
Ishii, DK1
de Morais, H1
de Carvalho, MC1
Rizzo de Souza, LE1
Zanata, SM1
Brandão, ML1
Cunha, TM1
Ferraz, AC1
Cunha, JM1
Zanoveli, JM1
Le Floc'h, N1
Melchior, D1
Sève, B1
Ronen, N1
Gross, B1
Ben-Shachar, D1
Livne, E1

Other Studies

8 other studies available for kynurenine and Weight Gain

ArticleYear
Benserazide, an Inhibitor of Peripheral Kynurenine Metabolism, Attenuates Olanzapine-Induced Weight Gain, Insulin Resistance, and Dyslipidemia in C57Bl/6j Mice.
    Molecular neurobiology, 2020, Volume: 57, Issue:1

    Topics: Animals; Antipsychotic Agents; Benserazide; Dyslipidemias; Female; Insulin Resistance; Kynurenine; M

2020
Kynurenine-Induced Aryl Hydrocarbon Receptor Signaling in Mice Causes Body Mass Gain, Liver Steatosis, and Hyperglycemia.
    Obesity (Silver Spring, Md.), 2021, Volume: 29, Issue:2

    Topics: Animals; Fatty Liver; Hyperglycemia; Kynurenine; Liver; Mice; Receptors, Aryl Hydrocarbon; Signal Tr

2021
Metabolomic alteration induced by psychotropic drugs: Short-term metabolite profile as a predictor of weight gain evolution.
    Clinical and translational science, 2021, Volume: 14, Issue:6

    Topics: Adult; Aged; Biomarkers; Cohort Studies; Female; Humans; Kynurenine; Male; Metabolomics; Middle Aged

2021
Inhibition of stress-induced hepatic tryptophan 2,3-dioxygenase exhibits antidepressant activity in an animal model of depressive behaviour.
    The international journal of neuropsychopharmacology, 2014, Volume: 17, Issue:6

    Topics: Allopurinol; Animals; Antidepressive Agents; Cerebral Cortex; Chronic Disease; Corticosterone; Depre

2014
The urinary ratio of 3-hydroxykynurenine/3-hydroxyanthranilic acid is an index to predicting the adverse effects of D-tryptophan in rats.
    Journal of nutritional science and vitaminology, 2014, Volume: 60, Issue:4

    Topics: 3-Hydroxyanthranilic Acid; Amino Acid Metabolism, Inborn Errors; Animals; Diet; Hydrolases; Kynureni

2014
Indoleamine-2,3-Dioxygenase/Kynurenine Pathway as a Potential Pharmacological Target to Treat Depression Associated with Diabetes.
    Molecular neurobiology, 2016, Volume: 53, Issue:10

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Blood Glucose; Cytokines; Depression; Diabetes Mel

2016
Dietary tryptophan helps to preserve tryptophan homeostasis in pigs suffering from lung inflammation.
    Journal of animal science, 2008, Volume: 86, Issue:12

    Topics: Animals; Antioxidants; Diet; Dietary Supplements; Female; Haptoglobins; Homeostasis; Kynurenine; Mal

2008
The effects of induced kynurenine pathway on immunocytochemical changes in rat tissues following excessive L-tryptophan consumption.
    Advances in experimental medicine and biology, 1996, Volume: 398

    Topics: Animals; Brain; Female; Fenclonine; Food, Fortified; Immunohistochemistry; Kynurenine; Lung; Muscle,

1996