kynurenine has been researched along with Trypanosomiasis, African in 2 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
Trypanosomiasis, African: A disease endemic among people and animals in Central Africa. It is caused by various species of trypanosomes, particularly T. gambiense and T. rhodesiense. Its second host is the TSETSE FLY. Involvement of the central nervous system produces African sleeping sickness. Nagana is a rapidly fatal trypanosomiasis of horses and other animals.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Human African trypanosomiasis, or sleeping sickness, is caused by the protozoan parasites Trypanosoma brucei rhodesiense or Trypanosoma brucei gambiense, and is a major cause of systemic and neurological disability throughout sub-Saharan Africa." | 1.35 | Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis. ( Barrett, MP; Bradley, B; Kennedy, PG; Rodgers, J; Stone, TW, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sternberg, JM | 1 |
| Forrest, CM | 1 |
| Dalton, RN | 1 |
| Turner, C | 1 |
| Rodgers, J | 2 |
| Stone, TW | 2 |
| Kennedy, PGE | 1 |
| Barrett, MP | 1 |
| Bradley, B | 1 |
| Kennedy, PG | 1 |
2 other studies available for kynurenine and Trypanosomiasis, African
| Article | Year |
|---|---|
Kynurenine Pathway Activation in Human African Trypanosomiasis.
Topics: Adolescent; Adult; Aged; Biomarkers; Central Nervous System; Female; Humans; Inflammation; Interfero | 2017 |
Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis.
Topics: Animals; Blood-Brain Barrier; Central Nervous System Protozoal Infections; Female; Inhibitory Concen | 2009 |