kynurenine has been researched along with Suicidal Ideation in 7 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
Suicidal Ideation: A risk factor for suicide attempts and completions, it is the most common of all suicidal behavior, but only a minority of ideators engage in overt self-harm.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Quinolinic acid was increased and kynurenic acid decreased over time in suicidal patients versus healthy controls." | 1.42 | A role for inflammatory metabolites as modulators of the glutamate N-methyl-D-aspartate receptor in depression and suicidality. ( Bay-Richter, C; Brundin, L; Erhardt, S; Guillemin, GJ; Lim, CK; Linderholm, KR; Samuelsson, M; Träskman-Bendz, L, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 5 (71.43) | 2.80 |
| Authors | Studies |
|---|---|
| Almulla, AF | 1 |
| Thipakorn, Y | 1 |
| Vasupanrajit, A | 1 |
| Tunvirachaisakul, C | 1 |
| Oxenkrug, G | 1 |
| Al-Hakeim, HK | 1 |
| Maes, M | 1 |
| Badawy, AA | 2 |
| Achtyes, E | 2 |
| Keaton, SA | 1 |
| Smart, L | 1 |
| Burmeister, AR | 1 |
| Heilman, PL | 1 |
| Krzyzanowski, S | 1 |
| Nagalla, M | 1 |
| Guillemin, GJ | 4 |
| Escobar Galvis, ML | 1 |
| Lim, CK | 3 |
| Muzik, M | 1 |
| Postolache, TT | 2 |
| Leach, R | 1 |
| Brundin, L | 4 |
| Bay-Richter, C | 1 |
| Linderholm, KR | 1 |
| Samuelsson, M | 2 |
| Träskman-Bendz, L | 2 |
| Erhardt, S | 2 |
| Sellgren, CM | 1 |
| Grit, J | 1 |
| Pålsson, E | 1 |
| Landén, M | 1 |
| Lundgren, K | 1 |
| Brundin, P | 1 |
| Fuchs, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Genetic Risk Factors Predictive of the Occurrence of Maternally Diagnosed Perinatal Depression in Women[NCT05175755] | 3,000 participants (Anticipated) | Interventional | 2023-09-25 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for kynurenine and Suicidal Ideation
| Article | Year |
|---|---|
The Tryptophan Catabolite or Kynurenine Pathway in a Major Depressive Episode with Melancholia, Psychotic Features and Suicidal Behaviors: A Systematic Review and Meta-Analysis.
Topics: Albumins; Amino Acids; Depressive Disorder, Major; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kyn | 2022 |
6 other studies available for kynurenine and Suicidal Ideation
| Article | Year |
|---|---|
Kynurenine pathway and suicidal ideation in treatment-resistant depression.
Topics: Depression; Depressive Disorder, Treatment-Resistant; Humans; Kynurenine; Suicidal Ideation; Suicide | 2023 |
Inflammation and kynurenine pathway dysregulation in post-partum women with severe and suicidal depression.
Topics: Adult; Cross-Sectional Studies; Depression, Postpartum; Female; Humans; Inflammation; Kynurenine; Po | 2020 |
Kynurenine pathway dysregulation in postpartum depression.
Topics: Depression, Postpartum; Female; Humans; Inflammation; Kynurenine; Postpartum Period; Suicidal Ideati | 2021 |
Regarding letter on "Kynurenine pathway dysregulation in postpartum depression", by Achtyes et al, 2020.
Topics: Depression, Postpartum; Female; Humans; Inflammation; Kynurenine; Postpartum Period; Suicidal Ideati | 2021 |
A role for inflammatory metabolites as modulators of the glutamate N-methyl-D-aspartate receptor in depression and suicidality.
Topics: Adult; Cytokines; Depressive Disorder; Female; Humans; Inflammation; Kynurenic Acid; Kynurenine; Mal | 2015 |
An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation.
Topics: Adolescent; Adult; Aged; Alleles; Carboxy-Lyases; Case-Control Studies; Child; Female; Humans; Infla | 2016 |