kynurenine has been researched along with Spasm in 5 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
Spasm: An involuntary contraction of a muscle or group of muscles. Spasms may involve SKELETAL MUSCLE or SMOOTH MUSCLE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These results highlight the importance of tryptophan-kynurenine metabolism in infantile spasms and provide evidence for new-targeted therapies such as indoleamine 2,3-dioxygenase 1 inhibition or microbiota manipulation to promote kynurenic acid production as a strategy to reduce spasms in infantile spasms." | 8.12 | Seizure modulation by the gut microbiota and tryptophan-kynurenine metabolism in an animal model of infantile spasms. ( Barrett, KT; Choudhary, A; Mayengbam, S; Mu, C; Rho, JM; Scantlebury, MH; Shearer, J, 2022) |
| "There was a statistically significant decrease of CSF kynurenic acid in patients with epileptic spasms compared to OND (p<0." | 8.12 | Decreased cerebrospinal fluid kynurenic acid in epileptic spasms: A biomarker of response to corticosteroids. ( Antony, J; Ardern-Holmes, S; Bandodkar, S; Dale, RC; Gill, D; Guillemin, GJ; Guller, A; Gupta, S; Han, VX; Heng, B; Innes, EA; Jones, HF; Kothur, K; Menezes, MP; Mohammad, S; Patel, S; Pires, AS; Tantsis, E; Troedson, C; Tsang, E; Webster, R; Wienholt, L; Yan, J, 2022) |
| "These results highlight the importance of tryptophan-kynurenine metabolism in infantile spasms and provide evidence for new-targeted therapies such as indoleamine 2,3-dioxygenase 1 inhibition or microbiota manipulation to promote kynurenic acid production as a strategy to reduce spasms in infantile spasms." | 4.12 | Seizure modulation by the gut microbiota and tryptophan-kynurenine metabolism in an animal model of infantile spasms. ( Barrett, KT; Choudhary, A; Mayengbam, S; Mu, C; Rho, JM; Scantlebury, MH; Shearer, J, 2022) |
| "There was a statistically significant decrease of CSF kynurenic acid in patients with epileptic spasms compared to OND (p<0." | 4.12 | Decreased cerebrospinal fluid kynurenic acid in epileptic spasms: A biomarker of response to corticosteroids. ( Antony, J; Ardern-Holmes, S; Bandodkar, S; Dale, RC; Gill, D; Guillemin, GJ; Guller, A; Gupta, S; Han, VX; Heng, B; Innes, EA; Jones, HF; Kothur, K; Menezes, MP; Mohammad, S; Patel, S; Pires, AS; Tantsis, E; Troedson, C; Tsang, E; Webster, R; Wienholt, L; Yan, J, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mu, C | 1 |
| Choudhary, A | 1 |
| Mayengbam, S | 1 |
| Barrett, KT | 1 |
| Rho, JM | 1 |
| Shearer, J | 1 |
| Scantlebury, MH | 1 |
| Yan, J | 1 |
| Kothur, K | 1 |
| Innes, EA | 1 |
| Han, VX | 1 |
| Jones, HF | 1 |
| Patel, S | 1 |
| Tsang, E | 1 |
| Webster, R | 1 |
| Gupta, S | 1 |
| Troedson, C | 1 |
| Menezes, MP | 1 |
| Antony, J | 1 |
| Ardern-Holmes, S | 1 |
| Tantsis, E | 1 |
| Mohammad, S | 1 |
| Wienholt, L | 1 |
| Pires, AS | 1 |
| Heng, B | 1 |
| Guillemin, GJ | 1 |
| Guller, A | 1 |
| Gill, D | 1 |
| Bandodkar, S | 1 |
| Dale, RC | 1 |
| CAREDDU, P | 1 |
| Raine, DN | 1 |
| Yokoyama, Y | 1 |
| Tada, K | 1 |
| Yoshida, T | 1 |
| Nakagawa, H | 1 |
| Arakawa, T | 1 |
5 other studies available for kynurenine and Spasm
| Article | Year |
|---|---|
Seizure modulation by the gut microbiota and tryptophan-kynurenine metabolism in an animal model of infantile spasms.
Topics: Animals; Disease Models, Animal; Gastrointestinal Microbiome; Humans; Kynurenine; Rats; Seizures; Sp | 2022 |
Decreased cerebrospinal fluid kynurenic acid in epileptic spasms: A biomarker of response to corticosteroids.
Topics: 3-Hydroxyanthranilic Acid; Adrenal Cortex Hormones; Animals; Biomarkers; Chromatography, Liquid; Epi | 2022 |
[CHANGES IN TRYPTOPHAN METABOLISM IN THE WINKING-NODDING SPASM IN INFANTS].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Blinking; Blood Chemical Analysis; Chromatogra | 1963 |
Effect of treatment on tryptophan metabolism in childhood epilepsy.
Topics: Adrenocorticotropic Hormone; Adult; Anticonvulsants; Central Nervous System Diseases; Child; Child, | 1969 |
Liver kynureninase activity of an infant with infantile spasm.
Topics: Aspartate Aminotransferases; Cerebral Palsy; Child; Child, Preschool; Erythrocytes; Female; Humans; | 1968 |