Page last updated: 2024-10-18

kynurenine and Prediabetic State

kynurenine has been researched along with Prediabetic State in 4 studies

Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.

Prediabetic State: The time period before the development of symptomatic diabetes. For example, certain risk factors can be observed in subjects who subsequently develop INSULIN RESISTANCE as in type 2 diabetes (DIABETES MELLITUS, TYPE 2).

Research Excerpts

ExcerptRelevanceReference
" In individuals with prediabetes, 3-hydroxykynurenine (OR per SD 0."8.02Associations between plasma kynurenines and cognitive function in individuals with normal glucose metabolism, prediabetes and type 2 diabetes: the Maastricht Study. ( Bakker, L; Dagnelie, PC; Eussen, SJPM; Köhler, S; Midttun, Ø; Ramakers, IHGB; Schram, MT; Stehouwer, CDA; Ueland, PM; van Boxtel, MPJ; van der Kallen, CJH; van Greevenbroek, MMJ; Verhey, FRJ; Wesselius, A, 2021)
" We assessed downstream tryptophan metabolites of the kynurenine pathway as predictors of acute myocardial infarction in patients with suspected stable angina pectoris."7.81Associations of plasma kynurenines with risk of acute myocardial infarction in patients with stable angina pectoris. ( Eussen, SJ; Mellgren, G; Meyer, K; Midttun, Ø; Nilsen, DW; Nordrehaug, JE; Nygård, O; Pedersen, ER; Strand, E; Svingen, GF; Tuseth, N; Ueland, PM; Ulvik, A, 2015)
" In individuals with prediabetes, 3-hydroxykynurenine (OR per SD 0."4.02Associations between plasma kynurenines and cognitive function in individuals with normal glucose metabolism, prediabetes and type 2 diabetes: the Maastricht Study. ( Bakker, L; Dagnelie, PC; Eussen, SJPM; Köhler, S; Midttun, Ø; Ramakers, IHGB; Schram, MT; Stehouwer, CDA; Ueland, PM; van Boxtel, MPJ; van der Kallen, CJH; van Greevenbroek, MMJ; Verhey, FRJ; Wesselius, A, 2021)
" We assessed downstream tryptophan metabolites of the kynurenine pathway as predictors of acute myocardial infarction in patients with suspected stable angina pectoris."3.81Associations of plasma kynurenines with risk of acute myocardial infarction in patients with stable angina pectoris. ( Eussen, SJ; Mellgren, G; Meyer, K; Midttun, Ø; Nilsen, DW; Nordrehaug, JE; Nygård, O; Pedersen, ER; Strand, E; Svingen, GF; Tuseth, N; Ueland, PM; Ulvik, A, 2015)
"About 350 million people worldwide have type 2 diabetes (T2D)."1.42Increased Plasma Levels of Xanthurenic and Kynurenic Acids in Type 2 Diabetes. ( Oxenkrug, GF, 2015)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Chailurkit, LO1
Chanprasertyothin, S1
Thongmung, N1
Sritara, P1
Ongphiphadhanakul, B1
Bakker, L1
Ramakers, IHGB1
van Boxtel, MPJ1
Schram, MT1
Stehouwer, CDA1
van der Kallen, CJH1
Dagnelie, PC1
van Greevenbroek, MMJ1
Wesselius, A1
Midttun, Ø2
Ueland, PM2
Verhey, FRJ1
Eussen, SJPM1
Köhler, S1
Pedersen, ER1
Tuseth, N1
Eussen, SJ1
Strand, E1
Svingen, GF1
Meyer, K1
Mellgren, G1
Ulvik, A1
Nordrehaug, JE1
Nilsen, DW1
Nygård, O1
Oxenkrug, GF1

Other Studies

4 other studies available for kynurenine and Prediabetic State

ArticleYear
Targeted metabolomics suggests a probable role of the FTO gene in the kynurenine pathway in prediabetes.
    PeerJ, 2022, Volume: 10

    Topics: Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Female; Genome-Wide Association Study; Genotype; Huma

2022
Associations between plasma kynurenines and cognitive function in individuals with normal glucose metabolism, prediabetes and type 2 diabetes: the Maastricht Study.
    Diabetologia, 2021, Volume: 64, Issue:11

    Topics: 3-Hydroxyanthranilic Acid; Aged; Biomarkers; Blood Glucose; Cognition; Cognitive Dysfunction; Cross-

2021
Associations of plasma kynurenines with risk of acute myocardial infarction in patients with stable angina pectoris.
    Arteriosclerosis, thrombosis, and vascular biology, 2015, Volume: 35, Issue:2

    Topics: Aged; Angina, Stable; Biomarkers; Coronary Angiography; Coronary Artery Disease; Diabetes Mellitus,

2015
Increased Plasma Levels of Xanthurenic and Kynurenic Acids in Type 2 Diabetes.
    Molecular neurobiology, 2015, Volume: 52, Issue:2

    Topics: 3-Hydroxyanthranilic Acid; Adult; Aged; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agen

2015