Page last updated: 2024-10-18

kynurenine and Pre-Eclampsia

kynurenine has been researched along with Pre-Eclampsia in 11 studies

Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.

Pre-Eclampsia: A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.

Research Excerpts

ExcerptRelevanceReference
" The present study examined the diagnostic ability of tryptophan catabolites (TRYCATs) and insulin resistance (IR) parameters in women with PE."8.31Maternal Tryptophan Catabolites and Insulin Resistance Parameters in Preeclampsia. ( Al-Hakeim, HK; Jasim, ZA; Stanek, A; Zolghadri, S, 2023)
"The prevalence of preeclampsia was significantly higher among women with plasma kynurenic acid concentrations greater than the 95th percentile than among those with concentrations in the 25th-75th percentile (11."5.38Maternal tryptophan and kynurenine pathway metabolites and risk of preeclampsia. ( Bjørke-Monsen, AL; Gjessing, HK; Magnus, P; Midttun, O; Nilsen, RM; Nygård, O; Pedersen, ER; Ueland, PM; Ulvik, A; Vollset, SE, 2012)
" The present study examined the diagnostic ability of tryptophan catabolites (TRYCATs) and insulin resistance (IR) parameters in women with PE."4.31Maternal Tryptophan Catabolites and Insulin Resistance Parameters in Preeclampsia. ( Al-Hakeim, HK; Jasim, ZA; Stanek, A; Zolghadri, S, 2023)
"The prevalence of preeclampsia was significantly higher among women with plasma kynurenic acid concentrations greater than the 95th percentile than among those with concentrations in the 25th-75th percentile (11."1.38Maternal tryptophan and kynurenine pathway metabolites and risk of preeclampsia. ( Bjørke-Monsen, AL; Gjessing, HK; Magnus, P; Midttun, O; Nilsen, RM; Nygård, O; Pedersen, ER; Ueland, PM; Ulvik, A; Vollset, SE, 2012)
"In 13 cases of early-onset severe preeclampsia and 14 cases of late-onset severe preeclampsia, the placentas were sampled at the surface of the maternal placenta."1.37[Metabolic footprint in conditioned culture medium of placental explants: a comparison between early-onset and late-onset severe preeclampsia]. ( Chen, SL; Huang, FF; Liu, DY; Luo, XM; Wang, CH, 2011)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (27.27)24.3611
2020's7 (63.64)2.80

Authors

AuthorsStudies
Zhao, YJ1
Zhou, C1
Wei, YY1
Li, HH1
Lei, W1
Boeldt, DS1
Wang, K1
Zheng, J1
Dupont, V1
Berg, AH1
Yamashita, M1
Huang, C1
Covarrubias, AE1
Ali, S1
Stotland, A1
Van Eyk, JE1
Jim, B2
Thadhani, R1
Karumanchi, SA1
Marsden, PA1
Gupta, S1
Petras, L1
Tufail, MU1
Rodriguez Salazar, JD1
Jasim, ZA1
Al-Hakeim, HK1
Zolghadri, S1
Stanek, A1
Broekhuizen, M1
Klein, T1
Hitzerd, E1
de Rijke, YB1
Schoenmakers, S1
Sedlmayr, P1
Danser, AHJ1
Merkus, D1
Reiss, IKM1
Worton, SA2
Pritchard, HAT1
Greenwood, SL2
Alakrawi, M1
Heazell, AEP1
Wareing, M2
Greenstein, A1
Myers, JE1
Heazell, AE1
Myers, J1
Liu, DY1
Chen, SL1
Wang, CH1
Luo, XM1
Huang, FF1
Nilsen, RM1
Bjørke-Monsen, AL1
Midttun, O1
Nygård, O1
Pedersen, ER1
Ulvik, A1
Magnus, P1
Gjessing, HK1
Vollset, SE1
Ueland, PM1
Gorbacheva, LN1

Reviews

2 reviews available for kynurenine and Pre-Eclampsia

ArticleYear
Hypertension in Pregnancy: What We Now Know.
    Current opinion in nephrology and hypertension, 2023, Mar-01, Volume: 32, Issue:2

    Topics: Animals; Female; Fetus; Humans; Hypertension; Kynurenine; Mice; Pre-Eclampsia; Pregnancy

2023
The kynurenine pathway; A new target for treating maternal features of preeclampsia?
    Placenta, 2019, 09-01, Volume: 84

    Topics: Apoptosis; Cell Differentiation; Drug Development; Female; Humans; Immunomodulation; Kynurenine; Met

2019

Other Studies

9 other studies available for kynurenine and Pre-Eclampsia

ArticleYear
Differential Distribution of Tryptophan-Metabolites in Fetal and Maternal Circulations During Normotensive and Preeclamptic Pregnancies.
    Reproductive sciences (Thousand Oaks, Calif.), 2022, Volume: 29, Issue:4

    Topics: Female; Fetus; Human Umbilical Vein Endothelial Cells; Humans; Kynurenine; Pre-Eclampsia; Pregnancy;

2022
Impaired renal reserve contributes to preeclampsia via the kynurenine and soluble fms-like tyrosine kinase 1 pathway.
    The Journal of clinical investigation, 2022, 10-17, Volume: 132, Issue:20

    Topics: Animals; Female; Humans; Hypertension; Ischemia; Kidney; Kynurenine; Mice; Nephrectomy; Placenta; Pl

2022
The curious case of tryptophan in pregnancy.
    The Journal of clinical investigation, 2022, 10-17, Volume: 132, Issue:20

    Topics: Animals; Female; Humans; Kynurenine; Mice; Placenta; Placenta Growth Factor; Pre-Eclampsia; Pregnanc

2022
Maternal Tryptophan Catabolites and Insulin Resistance Parameters in Preeclampsia.
    Biomolecules, 2023, 09-26, Volume: 13, Issue:10

    Topics: Case-Control Studies; Female; Humans; Insulin Resistance; Kynurenic Acid; Kynurenine; Pre-Eclampsia;

2023
l-Tryptophan-Induced Vasodilation Is Enhanced in Preeclampsia: Studies on Its Uptake and Metabolism in the Human Placenta.
    Hypertension (Dallas, Tex. : 1979), 2020, Volume: 76, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Arteries; Carrier Protein

2020
Kynurenine Relaxes Arteries of Normotensive Women and Those With Preeclampsia.
    Circulation research, 2021, 05-28, Volume: 128, Issue:11

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenylyl Cyclase Inhibitors; Adu

2021
[Metabolic footprint in conditioned culture medium of placental explants: a comparison between early-onset and late-onset severe preeclampsia].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2011, Volume: 31, Issue:9

    Topics: Chorionic Villi; Culture Media, Conditioned; Female; Humans; In Vitro Techniques; Kynurenine; Ornith

2011
Maternal tryptophan and kynurenine pathway metabolites and risk of preeclampsia.
    Obstetrics and gynecology, 2012, Volume: 119, Issue:6

    Topics: Adult; Female; Humans; Kynurenine; Norway; Overweight; Pre-Eclampsia; Pregnancy; Prevalence; Risk; T

2012
[Tryptophan metabolism via the kynurenine and serotonin pathways in pregnancy nephropathy].
    Akusherstvo i ginekologiia, 1978, Issue:11

    Topics: Female; Humans; Kidney Diseases; Kynurenine; Postpartum Period; Pre-Eclampsia; Pregnancy; Pregnancy

1978