kynurenine has been researched along with Pre-Eclampsia in 11 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
Pre-Eclampsia: A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study examined the diagnostic ability of tryptophan catabolites (TRYCATs) and insulin resistance (IR) parameters in women with PE." | 8.31 | Maternal Tryptophan Catabolites and Insulin Resistance Parameters in Preeclampsia. ( Al-Hakeim, HK; Jasim, ZA; Stanek, A; Zolghadri, S, 2023) |
| "The prevalence of preeclampsia was significantly higher among women with plasma kynurenic acid concentrations greater than the 95th percentile than among those with concentrations in the 25th-75th percentile (11." | 5.38 | Maternal tryptophan and kynurenine pathway metabolites and risk of preeclampsia. ( Bjørke-Monsen, AL; Gjessing, HK; Magnus, P; Midttun, O; Nilsen, RM; Nygård, O; Pedersen, ER; Ueland, PM; Ulvik, A; Vollset, SE, 2012) |
| " The present study examined the diagnostic ability of tryptophan catabolites (TRYCATs) and insulin resistance (IR) parameters in women with PE." | 4.31 | Maternal Tryptophan Catabolites and Insulin Resistance Parameters in Preeclampsia. ( Al-Hakeim, HK; Jasim, ZA; Stanek, A; Zolghadri, S, 2023) |
| "The prevalence of preeclampsia was significantly higher among women with plasma kynurenic acid concentrations greater than the 95th percentile than among those with concentrations in the 25th-75th percentile (11." | 1.38 | Maternal tryptophan and kynurenine pathway metabolites and risk of preeclampsia. ( Bjørke-Monsen, AL; Gjessing, HK; Magnus, P; Midttun, O; Nilsen, RM; Nygård, O; Pedersen, ER; Ueland, PM; Ulvik, A; Vollset, SE, 2012) |
| "In 13 cases of early-onset severe preeclampsia and 14 cases of late-onset severe preeclampsia, the placentas were sampled at the surface of the maternal placenta." | 1.37 | [Metabolic footprint in conditioned culture medium of placental explants: a comparison between early-onset and late-onset severe preeclampsia]. ( Chen, SL; Huang, FF; Liu, DY; Luo, XM; Wang, CH, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 7 (63.64) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, YJ | 1 |
| Zhou, C | 1 |
| Wei, YY | 1 |
| Li, HH | 1 |
| Lei, W | 1 |
| Boeldt, DS | 1 |
| Wang, K | 1 |
| Zheng, J | 1 |
| Dupont, V | 1 |
| Berg, AH | 1 |
| Yamashita, M | 1 |
| Huang, C | 1 |
| Covarrubias, AE | 1 |
| Ali, S | 1 |
| Stotland, A | 1 |
| Van Eyk, JE | 1 |
| Jim, B | 2 |
| Thadhani, R | 1 |
| Karumanchi, SA | 1 |
| Marsden, PA | 1 |
| Gupta, S | 1 |
| Petras, L | 1 |
| Tufail, MU | 1 |
| Rodriguez Salazar, JD | 1 |
| Jasim, ZA | 1 |
| Al-Hakeim, HK | 1 |
| Zolghadri, S | 1 |
| Stanek, A | 1 |
| Broekhuizen, M | 1 |
| Klein, T | 1 |
| Hitzerd, E | 1 |
| de Rijke, YB | 1 |
| Schoenmakers, S | 1 |
| Sedlmayr, P | 1 |
| Danser, AHJ | 1 |
| Merkus, D | 1 |
| Reiss, IKM | 1 |
| Worton, SA | 2 |
| Pritchard, HAT | 1 |
| Greenwood, SL | 2 |
| Alakrawi, M | 1 |
| Heazell, AEP | 1 |
| Wareing, M | 2 |
| Greenstein, A | 1 |
| Myers, JE | 1 |
| Heazell, AE | 1 |
| Myers, J | 1 |
| Liu, DY | 1 |
| Chen, SL | 1 |
| Wang, CH | 1 |
| Luo, XM | 1 |
| Huang, FF | 1 |
| Nilsen, RM | 1 |
| Bjørke-Monsen, AL | 1 |
| Midttun, O | 1 |
| Nygård, O | 1 |
| Pedersen, ER | 1 |
| Ulvik, A | 1 |
| Magnus, P | 1 |
| Gjessing, HK | 1 |
| Vollset, SE | 1 |
| Ueland, PM | 1 |
| Gorbacheva, LN | 1 |
2 reviews available for kynurenine and Pre-Eclampsia
| Article | Year |
|---|---|
Hypertension in Pregnancy: What We Now Know.
Topics: Animals; Female; Fetus; Humans; Hypertension; Kynurenine; Mice; Pre-Eclampsia; Pregnancy | 2023 |
The kynurenine pathway; A new target for treating maternal features of preeclampsia?
Topics: Apoptosis; Cell Differentiation; Drug Development; Female; Humans; Immunomodulation; Kynurenine; Met | 2019 |
9 other studies available for kynurenine and Pre-Eclampsia
| Article | Year |
|---|---|
Differential Distribution of Tryptophan-Metabolites in Fetal and Maternal Circulations During Normotensive and Preeclamptic Pregnancies.
Topics: Female; Fetus; Human Umbilical Vein Endothelial Cells; Humans; Kynurenine; Pre-Eclampsia; Pregnancy; | 2022 |
Impaired renal reserve contributes to preeclampsia via the kynurenine and soluble fms-like tyrosine kinase 1 pathway.
Topics: Animals; Female; Humans; Hypertension; Ischemia; Kidney; Kynurenine; Mice; Nephrectomy; Placenta; Pl | 2022 |
The curious case of tryptophan in pregnancy.
Topics: Animals; Female; Humans; Kynurenine; Mice; Placenta; Placenta Growth Factor; Pre-Eclampsia; Pregnanc | 2022 |
Maternal Tryptophan Catabolites and Insulin Resistance Parameters in Preeclampsia.
Topics: Case-Control Studies; Female; Humans; Insulin Resistance; Kynurenic Acid; Kynurenine; Pre-Eclampsia; | 2023 |
l-Tryptophan-Induced Vasodilation Is Enhanced in Preeclampsia: Studies on Its Uptake and Metabolism in the Human Placenta.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Arteries; Carrier Protein | 2020 |
Kynurenine Relaxes Arteries of Normotensive Women and Those With Preeclampsia.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenylyl Cyclase Inhibitors; Adu | 2021 |
[Metabolic footprint in conditioned culture medium of placental explants: a comparison between early-onset and late-onset severe preeclampsia].
Topics: Chorionic Villi; Culture Media, Conditioned; Female; Humans; In Vitro Techniques; Kynurenine; Ornith | 2011 |
Maternal tryptophan and kynurenine pathway metabolites and risk of preeclampsia.
Topics: Adult; Female; Humans; Kynurenine; Norway; Overweight; Pre-Eclampsia; Pregnancy; Prevalence; Risk; T | 2012 |
[Tryptophan metabolism via the kynurenine and serotonin pathways in pregnancy nephropathy].
Topics: Female; Humans; Kidney Diseases; Kynurenine; Postpartum Period; Pre-Eclampsia; Pregnancy; Pregnancy | 1978 |