Page last updated: 2024-10-18

kynurenine and Postoperative Complications

kynurenine has been researched along with Postoperative Complications in 6 studies

Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.

Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.

Research Excerpts

ExcerptRelevanceReference
" As such surgery is associated with signs of inflammation and pro-inflammatory mediators activate tryptophan oxidation to neuroactive kynurenines which modulate NMDA receptor function and oxidative stress, we have measured blood concentrations of kynurenines and inflammatory markers in 28 patients undergoing coronary arterial graft surgery and, for comparison, 28 patients undergoing non-bypass thoracic surgery."3.77Kynurenine metabolism predicts cognitive function in patients following cardiac bypass and thoracic surgery. ( Darlington, LG; Forrest, CM; Higgins, MJ; Mackay, GM; Millar, K; Oxford, L; Stone, TW, 2011)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Walker, JA1
Richards, S1
Whelan, SA1
Yoo, SB1
Russell, TL1
Arinze, N1
Lotfollahzadeh, S1
Napoleon, MA1
Belghasem, M1
Lee, N1
Dember, LM1
Ravid, K1
Chitalia, VC1
Davidson, JA1
Frank, BS1
Urban, TT1
Twite, M1
Jaggers, J1
Khailova, L1
Klawitter, J1
Meloni, F1
Giuliano, S1
Solari, N1
Draghi, P1
Miserere, S1
Bardoni, AM1
Salvini, R1
Bini, F1
Fietta, AM1
Forrest, CM1
Mackay, GM1
Oxford, L1
Millar, K1
Darlington, LG1
Higgins, MJ1
Stone, TW1
Teichmann, W1
Knapp, A1
Teichmann, E1
Holmes, EW1
Russell, PM1
Kinzler, GJ1
Reckard, CR1
Flanigan, RC1
Thompson, KD1
Bermes, EW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00113737]0 participants Interventional1998-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

6 other studies available for kynurenine and Postoperative Complications

ArticleYear
Indoleamine 2,3-dioxygenase-1, a Novel Therapeutic Target for Post-Vascular Injury Thrombosis in CKD.
    Journal of the American Society of Nephrology : JASN, 2021, Volume: 32, Issue:11

    Topics: Animals; Aorta; Carotid Artery Injuries; Carotid Artery Thrombosis; Culture Media; Enzyme Induction;

2021
Serum metabolic profile of postoperative acute kidney injury following infant cardiac surgery with cardiopulmonary bypass.
    Pediatric nephrology (Berlin, Germany), 2021, Volume: 36, Issue:10

    Topics: Acute Kidney Injury; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Humans; Infant; Kynurenine

2021
Indoleamine 2,3-dioxygenase in lung allograft tolerance.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2009, Volume: 28, Issue:11

    Topics: Biomarkers; Bronchiolitis Obliterans; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorb

2009
Kynurenine metabolism predicts cognitive function in patients following cardiac bypass and thoracic surgery.
    Journal of neurochemistry, 2011, Volume: 119, Issue:1

    Topics: Adult; Aged; Biomarkers; Chromatography, High Pressure Liquid; Cognition; Coronary Artery Bypass; En

2011
[Tryptophan metabolism in breast carcinoma].
    Zentralblatt fur Chirurgie, 1976, Volume: 101, Issue:1

    Topics: Aged; Breast Neoplasms; Female; Humans; Kynurenine; Menopause; Middle Aged; Postoperative Complicati

1976
Oxidative tryptophan metabolism in renal allograft recipients: increased kynurenine synthesis is associated with inflammation and OKT3 therapy.
    Cytokine, 1992, Volume: 4, Issue:3

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Biomarkers; Creatinine; Female; Graft Rejection; Gram-Ne

1992