Page last updated: 2024-10-18

kynurenine and Polycystic Kidney, Autosomal Dominant

kynurenine has been researched along with Polycystic Kidney, Autosomal Dominant in 2 studies

Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.

Polycystic Kidney, Autosomal Dominant: Kidney disorders with autosomal dominant inheritance and characterized by multiple CYSTS in both KIDNEYS with progressive deterioration of renal function.

Research Excerpts

ExcerptRelevanceReference
"There was a significant accumulation of kynurenine and kynurenic acid (KYNA) in children and adults with ADPKD as compared to healthy subjects."4.31Kynurenines in polycystic kidney disease. ( Cadnapaphornchai, MA; Chonchol, M; Christians, U; Gitomer, BY; Hopp, K; Jackson, MJ; Klawitter, J; Smith, PH, 2023)
"Further, IDO1 levels were increased in ADPKD cell lines."1.91The tryptophan-metabolizing enzyme indoleamine 2,3-dioxygenase 1 regulates polycystic kidney disease progression. ( Chonchol, MB; Clambey, ET; Dwivedi, N; Gitomer, BY; Hopp, K; Klawitter, J; Kleczko, EK; Monaghan, MT; Nemenoff, RA; Nguyen, DT, 2023)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's2 (100.00)2.80

Authors

AuthorsStudies
Klawitter, J5
Jackson, MJ1
Smith, PH1
Hopp, K4
Chonchol, M1
Gitomer, BY4
Cadnapaphornchai, MA1
Christians, U1
Nguyen, DT3
Kleczko, EK3
Dwivedi, N3
Monaghan, MT3
Chonchol, MB3
Clambey, ET3
Nemenoff, RA3

Other Studies

2 other studies available for kynurenine and Polycystic Kidney, Autosomal Dominant

ArticleYear
Kynurenines in polycystic kidney disease.
    Journal of nephrology, 2023, Volume: 36, Issue:1

    Topics: Adult; Child; Disease Progression; Glomerular Filtration Rate; Humans; Inflammation; Kidney; Kynuren

2023
The tryptophan-metabolizing enzyme indoleamine 2,3-dioxygenase 1 regulates polycystic kidney disease progression.
    JCI insight, 2023, 01-10, Volume: 8, Issue:1

    Topics: Animals; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Mice; Mice, Inbred C57BL; Mice, Knockout;

2023
The tryptophan-metabolizing enzyme indoleamine 2,3-dioxygenase 1 regulates polycystic kidney disease progression.
    JCI insight, 2023, 01-10, Volume: 8, Issue:1

    Topics: Animals; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Mice; Mice, Inbred C57BL; Mice, Knockout;

2023
The tryptophan-metabolizing enzyme indoleamine 2,3-dioxygenase 1 regulates polycystic kidney disease progression.
    JCI insight, 2023, 01-10, Volume: 8, Issue:1

    Topics: Animals; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Mice; Mice, Inbred C57BL; Mice, Knockout;

2023
The tryptophan-metabolizing enzyme indoleamine 2,3-dioxygenase 1 regulates polycystic kidney disease progression.
    JCI insight, 2023, 01-10, Volume: 8, Issue:1

    Topics: Animals; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Mice; Mice, Inbred C57BL; Mice, Knockout;

2023
The tryptophan-metabolizing enzyme indoleamine 2,3-dioxygenase 1 regulates polycystic kidney disease progression.
    JCI insight, 2023, 01-10, Volume: 8, Issue:1

    Topics: Animals; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Mice; Mice, Inbred C57BL; Mice, Knockout;

2023
The tryptophan-metabolizing enzyme indoleamine 2,3-dioxygenase 1 regulates polycystic kidney disease progression.
    JCI insight, 2023, 01-10, Volume: 8, Issue:1

    Topics: Animals; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Mice; Mice, Inbred C57BL; Mice, Knockout;

2023
The tryptophan-metabolizing enzyme indoleamine 2,3-dioxygenase 1 regulates polycystic kidney disease progression.
    JCI insight, 2023, 01-10, Volume: 8, Issue:1

    Topics: Animals; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Mice; Mice, Inbred C57BL; Mice, Knockout;

2023
The tryptophan-metabolizing enzyme indoleamine 2,3-dioxygenase 1 regulates polycystic kidney disease progression.
    JCI insight, 2023, 01-10, Volume: 8, Issue:1

    Topics: Animals; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Mice; Mice, Inbred C57BL; Mice, Knockout;

2023
The tryptophan-metabolizing enzyme indoleamine 2,3-dioxygenase 1 regulates polycystic kidney disease progression.
    JCI insight, 2023, 01-10, Volume: 8, Issue:1

    Topics: Animals; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Mice; Mice, Inbred C57BL; Mice, Knockout;

2023